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Drying Technology
An International Journal
Volume 24, 2006 - Issue 6
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Original Articles

Spray Freeze Drying in a Fluidized Bed at Normal and Low Pressure

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Pages 711-719 | Published online: 06 Feb 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (17)

Fan Zhang, Yanhua Li, Qing Xu, Ruifeng Liu, Zhilong Wang & Chi Ma. (2023) Nondestructive monitoring of freeze drying and spray freeze drying endpoint by temperature-pressure method. Drying Technology 0:0, pages 1-9.
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Mostafa Rostamnezhad, Hossein Jafari, Farzad Moradikhah, Sara Bahrainian, Homa Faghihi, Reza Khalvati, Reza Bafkary & Alireza Vatanara. (2022) Spray freeze-drying for inhalation application: process and formulation variables. Pharmaceutical Development and Technology 27:3, pages 251-267.
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M. N. Lavanya, R. Preethi, J. A. Moses & C. Anandharamakrishnan. (2021) Production of bromelain aerosols using spray-freeze-drying technique for pulmonary supplementation. Drying Technology 39:3, pages 358-370.
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Lin Cao, Qinglian Xu, Yage Xing, Xunlian Guo, Wenxiu Li & Yimin Cai. (2020) Effect of skimmed milk powder concentrations on the biological characteristics of microencapsulated Saccharomyces cerevisiae by vacuum-spray-freeze-drying. Drying Technology 38:4, pages 476-494.
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Fan Zhang, Xiaoyu Ma, Xiusheng Wu, Qing Xu, Wei Tian & Zhanyong Li. (2020) Inert particles as process aid in spray-freeze drying. Drying Technology 38:1-2, pages 71-79.
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E. Flores-Andrade, E. Bonilla, G. Luna-Solano, U. R. Marín, M. T. González-Arnao & M. P. Rascón. (2019) Effect of the microstructure on the stability of red onion microcapsules. Drying Technology 37:2, pages 223-231.
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E. Flores-Andrade, L. A. Pascual-Pineda, M. X. Quintanilla-Carvajal, G. F. Gutiérrez-López, C. I. Beristain & E. Azuara. (2018) Fractal surface analysis and thermodynamic properties of moisture sorption of calcium–sucrose powders. Drying Technology 36:9, pages 1128-1141.
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Xu Duan, Xiaotong Yang, Guangyue Ren, Yuqi Pang, Lili Liu & Yunhong Liu. (2016) Technical aspects in freeze-drying of foods. Drying Technology 34:11, pages 1271-1285.
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Qing Xu, Zhanyong Li, Jin Wang & Ruifang Wang. (2012) Characteristics of Single Droplet Impact on Cold Plate Surfaces. Drying Technology 30:15, pages 1756-1762.
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Tamás Antal, Adam Figiel, Benedek Kerekes & László Sikolya. (2011) Effect of Drying Methods on the Quality of the Essential Oil of Spearmint Leaves (Mentha spicata L.). Drying Technology 29:15, pages 1836-1844.
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C. Anandharamakrishnan, J. Gimbun, A. G. F. Stapley & C. D. Rielly. (2009) Application of Computational Fluid Dynamics (CFD) Simulations to Spray-Freezing Operations. Drying Technology 28:1, pages 94-102.
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Samuel Rogers, Winston Duo Wu, Jonathan Saunders & Xiao Dong Chen. (2008) Characteristics of Milk Powders Produced by Spray Freeze Drying. Drying Technology 26:4, pages 404-412.
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ArunS. Mujumdar & Wu Zhonghua. (2007) Thermal Drying Technologies—Cost-Effective Innovation Aided by Mathematical Modeling Approach. Drying Technology 26:1, pages 145-153.
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I. C. Claussen, T. S. Ustad, I. Str⊘mmen & P. M. Walde. (2007) Atmospheric Freeze Drying—A Review. Drying Technology 25:6, pages 947-957.
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Ioan Cristian Trelea, Stéphanie Passot, Fernanda Fonseca & Michèle Marin. (2007) An Interactive Tool for the Optimization of Freeze-Drying Cycles Based on Quality Criteria. Drying Technology 25:5, pages 741-751.
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Articles from other publishers (29)

Bernhard Luy, Matthias Plitzko & Howard Stamato. 2023. Principles and Practices of Lyophilization in Product Development and Manufacturing. Principles and Practices of Lyophilization in Product Development and Manufacturing 243 268 .
Alberto Baldelli, Hale Oguzlu, Diana Yumeng Liang, Alison Subiantoro, Meng Wai Woo & Anubhav Pratap-Singh. (2022) Spray freeze drying of dairy products: Effect of formulation on dispersibility. Journal of Food Engineering 335, pages 111191.
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Yingjie Chen, Shen Yan, Shengyu Zhang, Quanyi Yin, Xiao Dong Chen & Winston Duo Wu. (2022) Micro-fluidic Spray Freeze Dried Ciprofloxacin Hydrochloride-Embedded Dry Powder for Inhalation. AAPS PharmSciTech 23:6.
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Yuheng Shang, Bofeng Bai, Yu Hou, Xin Zhong & Lidong Sun. (2022) Alteration of freezing paradigms of an impact water droplet on different cold surfaces. International Journal of Heat and Mass Transfer 183, pages 122177.
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Chinmayee Sarode, Yashraj Jagtap & Parag Gogate. 2022. Optimization of Pharmaceutical Processes. Optimization of Pharmaceutical Processes 193 229 .
Merve B. Adali, Antonello A. Barresi, Gianluca Boccardo & Roberto Pisano. (2020) Spray Freeze-Drying as a Solution to Continuous Manufacturing of Pharmaceutical Products in Bulk. Processes 8:6, pages 709.
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Bernhard Luy & Howard Stamato. 2020. Drying Technologies for Biotechnology and Pharmaceutical Applications. Drying Technologies for Biotechnology and Pharmaceutical Applications 217 237 .
Israel B. Sebastião, Bakul Bhatnagar, Serguei Tchessalov, Satoshi Ohtake, Matthias Plitzko, Bernhard Luy & Alina Alexeenko. (2019) Bulk Dynamic Spray Freeze-Drying Part 1: Modeling of Droplet Cooling and Phase Change. Journal of Pharmaceutical Sciences 108:6, pages 2063-2074.
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Alvin Ly, Nicholas B. Carrigy, Hui Wang, Melissa Harrison, Dominic Sauvageau, Andrew R. Martin, Reinhard Vehring & Warren H. Finlay. (2019) Atmospheric Spray Freeze Drying of Sugar Solution With Phage D29. Frontiers in Microbiology 10.
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C. Anandharamakrishnan. 2019. Caffeinated and Cocoa Based Beverages. Caffeinated and Cocoa Based Beverages 337 366 .
. 2018. Ice Templating and Freeze‐Drying for Porous Materials and Their Applications. Ice Templating and Freeze‐Drying for Porous Materials and Their Applications 63 102 .
S. Padma Ishwarya, C. Anandharamakrishnan & A.G.F. Stapley. 2017. Handbook of Drying for Dairy Products. Handbook of Drying for Dairy Products 123 148 .
Stefan Wanning, Richard Süverkrüp & Alf Lamprecht. (2017) Jet-vortex spray freeze drying for the production of inhalable lyophilisate powders. European Journal of Pharmaceutical Sciences 96, pages 1-7.
Crossref
Marine Camblin, Benjamin Berger, Manuel Haschke, Stephan Krähenbühl, Jörg Huwyler & Maxim Puchkov. (2016) CombiCap: A novel drug formulation for the basel phenotyping cocktail. International Journal of Pharmaceutics 512:1, pages 253-261.
Crossref
R. Rajam & C. Anandharamakrishnan. (2015) Spray freeze drying method for microencapsulation of Lactobacillus plantarum. Journal of Food Engineering 166, pages 95-103.
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Zi Zhang, Da-Wen Sun, Zhiwei Zhu & Lina Cheng. (2015) Enhancement of Crystallization Processes by Power Ultrasound: Current State-of-the-Art and Research Advances. Comprehensive Reviews in Food Science and Food Safety 14:4, pages 303-316.
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Stefan Wanning, Richard Süverkrüp & Alf Lamprecht. (2015) Pharmaceutical spray freeze drying. International Journal of Pharmaceutics 488:1-2, pages 136-153.
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S. Padma Ishwarya, C. Anandharamakrishnan & Andrew G.F. Stapley. (2015) Spray-freeze-drying: A novel process for the drying of foods and bioproducts. Trends in Food Science & Technology 41:2, pages 161-181.
Crossref
Robert H. Walters, Bakul Bhatnagar, Serguei Tchessalov, Ken-Ichi Izutsu, Kouhei Tsumoto & Satoshi Ohtake. (2014) Next Generation Drying Technologies for Pharmaceutical Applications. Journal of Pharmaceutical Sciences 103:9, pages 2673-2695.
Crossref
Jatindra SahuChung Law, Wan Daud & Arun Mujumdar. 2014. Introduction to Advanced Food Process Engineering. Introduction to Advanced Food Process Engineering 31 78 .
Roberto Pisano, Davide Fissore & Antonello A. Barresi. 2014. Modern Drying Technology. Modern Drying Technology 131 161 .
Roberto Pisano, Davide Fissore & Antonello A. Barresi. 2014. Modern Drying Technology. Modern Drying Technology 131 161 .
Xu Duan, Ling Ding, Guang-yue Ren, Li-li Liu & Qiu-zhen Kong. (2013) The drying strategy of atmospheric freeze drying apple cubes based on glass transition. Food and Bioproducts Processing 91:4, pages 534-538.
Crossref
Garima Sharma, Wunlapa Mueannoom, Asma B.M. Buanz, Kevin M.G. Taylor & Simon Gaisford. (2013) In vitro characterisation of terbutaline sulphate particles prepared by thermal ink-jet spray freeze drying. International Journal of Pharmaceutics 447:1-2, pages 165-170.
Crossref
Wunlapa Mueannoom, Amon Srisongphan, Kevin M.G. Taylor, Stephan Hauschild & Simon Gaisford. (2012) Thermal ink-jet spray freeze-drying for preparation of excipient-free salbutamol sulphate for inhalation. European Journal of Pharmaceutics and Biopharmaceutics 80:1, pages 149-155.
Crossref
Ahmad M. Abdul‐Fattah & Vu L. Truong. 2010. Formulation and Process Development Strategies for Manufacturing Biopharmaceuticals. Formulation and Process Development Strategies for Manufacturing Biopharmaceuticals 705 738 .
Arun S. Mujumdar, Li-Xin Huang & Xiao Dong Chen. (2010) An overview of the recent advances in spray-drying. Dairy Science & Technology 90:2-3, pages 211-224.
Crossref
Chinnaswamy Anandharamakrishnan, Chris D. Rielly & Andrew G. F. Stapley. (2010) Spray-freeze-drying of whey proteins at sub-atmospheric pressures. Dairy Science & Technology 90:2-3, pages 321-334.
Crossref
Tadeusz Kudra & Arun Mujumdar. 2009. Advanced Drying Technologies, Second Edition. Advanced Drying Technologies, Second Edition 337 341 .

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