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Drying Technology
An International Journal
Volume 31, 2013 - Issue 13-14: Drying of Proteins and Enzymes
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Original Articles

Designing a Multicomponent Spray-Dried Formulation Platform for Pulmonary Delivery of Biomacromolecules: The Effect of Polymers on the Formation of an Amorphous Matrix for Glassy State Stabilization of Biomacromolecules

Tomás Sou Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia
,
Michelle P. McIntosh Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia
,
Lisa M. Kaminskas Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia
,
Richard J. Prankerd Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia
&
David A. V. Morton Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, AustraliaCorrespondence[email protected]
Pages 1451-1458 | Published online: 26 Sep 2013

Citations (20)

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Laura Deruyver, Clément Rigaut, Alejandro Gomez-Perez, Pierre Lambert, Benoit Haut & Jonathan Goole. (2023) In vitro Evaluation of Paliperidone Palmitate Loaded Cubosomes Effective for Nasal-to-Brain Delivery. International Journal of Nanomedicine 18, pages 1085-1106.
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Alberto Baldelli, Aylin Cidem, Yigong Guo, Hui Xin Ong, Anika Singh, Daniela Traini & Anubhav Pratap-Singh. (2023) Spray freeze drying for protein encapsulation: Impact of the formulation to morphology and stability. Drying Technology 41:1, pages 137-150.
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Ji-Hyun Kang, Min-Seok Yang, Dong-Wook Kim & Chun-Woong Park. (2022) In vivo pharmacokinetic and pharmacodynamic study of co-spray-dried inhalable pirfenidone microparticles in rats. Drug Delivery 29:1, pages 3384-3396.
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Articles from other publishers (17)

Katharina Tatjana Kopp, Lien Saerens, Jody Voorspoels & Guy Van den Mooter. (2023) Solidification and oral delivery of biologics to the colon- A review. European Journal of Pharmaceutical Sciences 190, pages 106523.
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Moustafa M. Abdelaziz, Amr Hefnawy, Asem Anter, Menna M. Abdellatif, Mahmoud A.F. Khalil & Islam A. Khalil. (2022) Respirable spray dried vancomycin coated magnetic nanoparticles for localized lung delivery. International Journal of Pharmaceutics 611, pages 121318.
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Shaimaa Makled, Nabila Boraie & Noha Nafee. (2020) Nanoparticle-mediated macrophage targeting—a new inhalation therapy tackling tuberculosis. Drug Delivery and Translational Research 11:3, pages 1037-1055.
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Nasser Alhajj, Niall J. O'Reilly & Helen Cathcart. (2021) Designing enhanced spray dried particles for inhalation: A review of the impact of excipients and processing parameters on particle properties. Powder Technology 384, pages 313-331.
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Tomás Sou & Christel A.S. Bergström. (2021) Contemporary Formulation Development for Inhaled Pharmaceuticals. Journal of Pharmaceutical Sciences 110:1, pages 66-86.
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Hadeer M. Abdelaziz, Ahmed O. Elzoghby, Maged W. Helmy, Elsayeda-Zeinab A. Abdelfattah, Jia-You Fang, Magda W. Samaha & May S. Freag. (2020) Inhalable Lactoferrin/Chondroitin-Functionalized Monoolein Nanocomposites for Localized Lung Cancer Targeting. ACS Biomaterials Science & Engineering 6:2, pages 1030-1042.
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Mohammad A.M. Momin, Bhamini Rangnekar, Ian Larson, Shubhra Sinha & Shyamal C. Das. (2019) Dry powder formulation combining bedaquiline with pyrazinamide for latent and drug-resistant tuberculosis. Advanced Powder Technology 30:11, pages 2473-2482.
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Mohammad A. M. Momin, Bhamini Rangnekar, Shubhra Sinha, Chen-Yi Cheung, Gregory M. Cook & Shyamal C. Das. (2019) Inhalable Dry Powder of Bedaquiline for Pulmonary Tuberculosis: In Vitro Physicochemical Characterization, Antimicrobial Activity and Safety Studies. Pharmaceutics 11:10, pages 502.
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Daniel A. LeClair, Lillian Li, Nausheen Rahman, Emily D. Cranston, Zhou Xing & Michael R. Thompson. (2019) Stabilization of HSV-2 viral vaccine candidate by spray drying. International Journal of Pharmaceutics 569, pages 118615.
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Mayada M Elgohary, Maged W Helmy, Sana M Mortada & Ahmed O Elzoghby. (2018) Dual-targeted nano-in-nano albumin carriers enhance the efficacy of combined chemo/herbal therapy of lung cancer. Nanomedicine 13:17, pages 2221-2224.
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Dalia M. Kabary, Maged W. Helmy, Elsayeda-Zeinab A. Abdelfattah, Jia-You Fang, Kadria A. Elkhodairy & Ahmed O. Elzoghby. (2018) Inhalable multi-compartmental phospholipid enveloped lipid core nanocomposites for localized mTOR inhibitor/herbal combined therapy of lung carcinoma. European Journal of Pharmaceutics and Biopharmaceutics 130, pages 152-164.
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Mohammad A.M. Momin, Ian G. Tucker, Colin S. Doyle, John A. Denman, Shubhra Sinha & Shyamal C. Das. (2018) Co-spray drying of hygroscopic kanamycin with the hydrophobic drug rifampicin to improve the aerosolization of kanamycin powder for treating respiratory infections. International Journal of Pharmaceutics 541:1-2, pages 26-36.
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L. S. Usmanova, M. A. Ziganshin, I. T. Rakipov, N. M. Lyadov, A. E. Klimovitskii, T. A. Mukhametzyanov & A. V. Gerasimov. (2018) Microspherical Particles of Solid Dispersion of Polyvinylpyrrolidone K29-32 for Inhalation Administration. BioMed Research International 2018, pages 1-12.
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Lan Chen, Tomoyuki Okuda, Xiang-Yun Lu & Hak-Kim Chan. (2016) Amorphous powders for inhalation drug delivery. Advanced Drug Delivery Reviews 100, pages 102-115.
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Satu Lakio, David A.V. Morton, Anna P. Ralph & Pete Lambert. (2015) Optimizing aerosolization of a high-dose L-arginine powder for pulmonary delivery. Asian Journal of Pharmaceutical Sciences 10:6, pages 528-540.
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Rania A.H. Ishak & Rihab Osman. (2015) Lecithin/TPGS-based spray-dried self-microemulsifying drug delivery systems: In vitro pulmonary deposition and cytotoxicity. International Journal of Pharmaceutics 485:1-2, pages 249-260.
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En-Yu Xu, Jing Guo, Ying Xu, Hao-Ying Li & Peter C. Seville. (2014) Influence of excipients on spray-dried powders for inhalation. Powder Technology 256, pages 217-223.
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