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Articles

Structural conversion of the transformer protein RfaH: new insights derived from protein structure prediction and molecular dynamics simulations

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Pages 2173-2179 | Received 27 Oct 2014, Accepted 29 Nov 2014, Published online: 12 Jan 2015

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Philipp K Zuber, Tina Daviter, Ramona Heißmann, Ulrike Persau, Kristian Schweimer & Stefan H Knauer. (2022) Structural and thermodynamic analyses of the β-to-α transformation in RfaH reveal principles of fold-switching proteins. eLife 11.
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Pablo Galaz‐Davison, Diego U. Ferreiro & César A. Ramírez‐Sarmiento. (2022) Coevolution‐derived native and non‐native contacts determine the emergence of a novel fold in a universally conserved family of transcription factors. Protein Science 31:6.
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Yiqiao Wang, Luyuan Zhao, Xuejie Zhou, Jian Zhang, Jun Jiang & Hao Dong. (2022) Global Fold Switching of the RafH Protein: Diverse Structures with a Conserved Pathway. The Journal of Physical Chemistry B 126:16, pages 2979-2989.
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Irina Artsimovitch & César A. Ramírez-Sarmiento. (2022) Metamorphic proteins under a computational microscope: Lessons from a fold-switching RfaH protein. Computational and Structural Biotechnology Journal 20, pages 5824-5837.
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Bahman Seifi, Adekunle Aina & Stefan Wallin. (2020) Structural fluctuations and mechanical stabilities of the metamorphic protein RfaH . Proteins: Structure, Function, and Bioinformatics 89:3, pages 289-300.
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Bing Wang & Irina Artsimovitch. (2021) NusG, an Ancient Yet Rapidly Evolving Transcription Factor. Frontiers in Microbiology 11.
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Pablo Galaz-Davison, José Alejandro Molina, Steve Silletti, Elizabeth A. Komives, Stefan H. Knauer, Irina Artsimovitch & César A. Ramírez-Sarmiento. (2020) Differential Local Stability Governs the Metamorphic Fold Switch of Bacterial Virulence Factor RfaH. Biophysical Journal 118:1, pages 96-104.
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Nathan A. Bernhardt & Ulrich H. E. Hansmann. (2018) Multifunnel Landscape of the Fold-Switching Protein RfaH-CTD. The Journal of Physical Chemistry B 122:5, pages 1600-1607.
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Da Shi, Dmitri Svetlov, Ruben Abagyan & Irina Artsimovitch. (2017) Flipping states: a few key residues decide the winning conformation of the only universally conserved transcription factor. Nucleic Acids Research 45:15, pages 8835-8843.
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Rajesh K. Pathak, Mamta Baunthiyal, Rohit Shukla, Dinesh Pandey, Gohar Taj & Anil Kumar. (2017) In Silico Identification of Mimicking Molecules as Defense Inducers Triggering Jasmonic Acid Mediated Immunity against Alternaria Blight Disease in Brassica Species. Frontiers in Plant Science 8.
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Jeevan B. GC, Bernard S. Gerstman & Prem P. Chapagain. (2015) The Role of the Interdomain Interactions on RfaH Dynamics and Conformational Transformation. The Journal of Physical Chemistry B 119:40, pages 12750-12759.
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