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Research Articles

GdmCl-induced unfolding studies of human carbonic anhydrase IX: a combined spectroscopic and MD simulation approach

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Pages 1295-1306 | Received 17 Mar 2016, Accepted 13 Apr 2016, Published online: 20 May 2016

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Ahmad Abu Turab Naqvi, Deeba Shamim Jairajpuri, Afzal Hussain, Gulam Mustafa Hasan, Mohamed F. Alajmi & Md. Imtaiyaz Hassan. (2021) Impact of glioblastoma multiforme associated mutations on the structure and function of MAP/microtubule affinity regulating kinase 4. Journal of Biomolecular Structure and Dynamics 39:5, pages 1781-1794.
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Amresh Prakash, Vijay Kumar, Atanu Banerjee, Andrew M. Lynn & Rajendra Prasad. (2021) Structural heterogeneity in RNA recognition motif 2 (RRM2) of TAR DNA-binding protein 43 (TDP-43): clue to amyotrophic lateral sclerosis. Journal of Biomolecular Structure and Dynamics 39:1, pages 357-367.
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Ruhar Singh, Naveen Kumar Meena, Trishala Das, Ravi Datta Sharma, Amresh Prakash & Andrew M. Lynn. (2020) Delineating the conformational dynamics of intermediate structures on the unfolding pathway of β-lactoglobulin in aqueous urea and dimethyl sulfoxide. Journal of Biomolecular Structure and Dynamics 38:17, pages 5027-5036.
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Preeti Pandey, Naveen Kumar Meena, Amresh Prakash, Vijay Kumar, Andrew M. Lynn & Faizan Ahmad. (2020) Characterization of heterogeneous intermediate ensembles on the guanidinium chloride-induced unfolding pathway of β-lactoglobulin. Journal of Biomolecular Structure and Dynamics 38:4, pages 1042-1053.
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Amresh Prakash, Vijay Kumar, Naveen Kumar Meena, Md. Imtaiyaz Hassan & Andrew M. Lynn. (2019) Comparative analysis of thermal unfolding simulations of RNA recognition motifs (RRMs) of TAR DNA-binding protein 43 (TDP-43). Journal of Biomolecular Structure and Dynamics 37:1, pages 178-194.
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Sunayana Begum Syed, Mohd Shahbaaz, Sabab Hassan Khan, Saurabha Srivastava, Asimul Islam, Faizan Ahmad & Md. Imtaiyaz Hassan. (2019) Estimation of pH effect on the structure and stability of kinase domain of human integrin-linked kinase. Journal of Biomolecular Structure and Dynamics 37:1, pages 156-165.
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Amresh Prakash, Vijay Kumar, Preeti Pandey, Deepak R. Bharti, Poonam Vishwakarma, Ruhar Singh, Md. Imtaiyaz Hassan & Andrew M. Lynn. (2018) Solvent sensitivity of protein aggregation in Cu, Zn superoxide dismutase: a molecular dynamics simulation study. Journal of Biomolecular Structure and Dynamics 36:10, pages 2605-2617.
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Amresh Prakash, Gunjan Dixit, Naveen Kumar Meena, Ruhar Singh, Poonam Vishwakarma, Smriti Mishra & Andrew M. Lynn. (2018) Elucidation of stable intermediates in urea-induced unfolding pathway of human carbonic anhydrase IX. Journal of Biomolecular Structure and Dynamics 36:9, pages 2391-2406.
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Md Imtaiyaz Hassan, Mohd. Umair, Yash Mathur, Taj Mohammad, Afreen Khan, Md Nayab Sulaimani, Afsar Alam & Asimul Islam. 2023. Protein Folding Dynamics and Stability. Protein Folding Dynamics and Stability 221 249 .
Divya Rai, Satyajit Khatua & Srabani Taraphder. (2022) Structure and Dynamics of the Isozymes II and IX of Human Carbonic Anhydrase. ACS Omega 7:35, pages 31149-31166.
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Taj Mohammad, Mohd. Amir, Kartikay Prasad, Sagar Batra, Vijay Kumar, Afzal Hussain, Md. Tabish Rehman, Mohamed F. AlAjmi & Md. Imtaiyaz Hassan. (2020) Impact of amino acid substitution in the kinase domain of Bruton tyrosine kinase and its association with X-linked agammaglobulinemia. International Journal of Biological Macromolecules 164, pages 2399-2408.
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Preeti Gupta, Faez Iqbal Khan, Dilkash Ambreen, Dakun Lai, Mohamed F. Alajmi, Afzal Hussain, Asimul Islam, Faizan Ahmad & Md. Imtaiyaz Hassan. (2020) Investigation of guanidinium chloride-induced unfolding pathway of sphingosine kinase 1. International Journal of Biological Macromolecules 147, pages 177-186.
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Ahmad Abu Turab Naqvi, Mohamed F. Alajmi, Tabish Rehman, Afzal Hussain & Imtaiyaz Hassan. (2019) Effects of Pro1266Leu mutation on structure and function of glycoprotein Ib binding domain of von Willebrand factor. Journal of Cellular Biochemistry 120:10, pages 17847-17857.
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Mongre, Mishra, Prakash, Jung, Lee, Kumari, Hong & Lee. (2019) Novel Carbazole-Piperazine Hybrid Small Molecule Induces Apoptosis by Targeting BCL-2 and Inhibits Tumor Progression in Lung Adenocarcinoma in Vitro and Xenograft Mice Model. Cancers 11:9, pages 1245.
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Anindya Biswas, Semanti Ghosh, Debabrata Sinha, Anindya Dutta, Soham Seal, Angshuman Bagchi & Subrata Sau. (2019) Dimerization ability, denaturation mechanism, and the stability of a staphylococcal phage repressor and its two domains. International Journal of Biological Macromolecules 124, pages 903-914.
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Rui-Rui Wang, Ying Ma, Shan Du, Wei-Ya Li, Ying-Zhan Sun, Hui Zhou & Run-Ling Wang. (2019) Exploring the reason for increased activity of SHP2 caused by D61Y mutation through molecular dynamics. Computational Biology and Chemistry 78, pages 133-143.
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Sunayana Begum Syed, Faez Iqbal Khan, Sabab Hasan Khan, Saurabha Srivastava, Gulam Mustafa Hasan, Kevin A. Lobb, Asimul Islam, Md. Imtaiyaz Hassan & Faizan Ahmad. (2018) Unravelling the unfolding mechanism of human integrin linked kinase by GdmCl-induced denaturation. International Journal of Biological Macromolecules 117, pages 1252-1263.
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Amresh Prakash, Vijay Kumar, Naveen Kumar Meena & Andrew M. Lynn. (2018) Elucidation of the structural stability and dynamics of heterogeneous intermediate ensembles in unfolding pathway of the N-terminal domain of TDP-43. RSC Advances 8:35, pages 19835-19845.
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Aarfa Queen, Parvez Khan, Danish Idrees, Amir Azam & Md. Imtaiyaz Hassan. (2018) Biological evaluation of p-toluene sulphonylhydrazone as carbonic anhydrase IX inhibitors: An approach to fight hypoxia-induced tumors. International Journal of Biological Macromolecules 106, pages 840-850.
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Danish Idrees, Safikur Rahman, Mohd. Shahbaaz, Md. Anzarul Haque, Asimul Islam, Faizan Ahmad & Md. Imtaiyaz Hassan. (2017) Estimation of thermodynamic stability of human carbonic anhydrase IX from urea-induced denaturation and MD simulation studies. International Journal of Biological Macromolecules 105, pages 183-189.
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