Advanced search
Publication Cover
Journal of Biomolecular Structure and Dynamics Volume 40, 2022 - Issue 20
Journal homepage
213
Views
2
CrossRef citations to date
0
Altmetric
Research Articles

Computational study of novel inhibitory molecule, 1-(4-((2S,3S)-3-amino-2-hydroxy-4-phenylbutyl)piperazin-1-yl)-3-phenylurea, with high potential to competitively block ATP binding to the RNA dependent RNA polymerase of SARS-CoV-2 virus

Prem Prakash Sharmaa Laboratory for Translational Chemistry and Drug Discovery, Department of Chemistry, Hansraj College, University of Delhi, Delhi, India
,
Sumit Kumarb Department of Chemistry, Miranda House, University of Delhi, Delhi, India
,
Sukrit Srivastavaa Laboratory for Translational Chemistry and Drug Discovery, Department of Chemistry, Hansraj College, University of Delhi, Delhi, India;c Infection Biology Group, Indian Foundation for Fundamental Research, Rae Bareli, IndiaORCID Iconhttps://orcid.org/0000-0003-0295-0272
ORCID Icon,
Mitul Srivastavad Translational Health Science and Technology Institute (THSTI), Haryana, India
,
Babban Jeee Department of Health Research, Ministry of Health and Family Welfare Government of India, New Delhi, IndiaORCID Iconhttps://orcid.org/0000-0002-2530-1489
ORCID Icon,
Nikolay Yu. Gorobetsf Department of Organic and Bioorganic Chemistry, State Scientific Institution ‘Institute for Single Crystals’ of National Academy of Science of Ukraine, Kharkiv, Ukraine
,
Dhruv Kumarg Amity Institute of Molecular Medicine & Stem Cell Research (AIMMSCR), Amity University Uttar Pradesh, Noida, India
,
Mukesh Kumarh Department of Biology, College of Arts and Sciences, Georgia State University, Atlanta, GA, USAORCID Iconhttps://orcid.org/0000-0003-0970-4875
ORCID Icon,
Shailendra Asthanad Translational Health Science and Technology Institute (THSTI), Haryana, India
,
Peng Zhangi Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, PR China
,
Poonamb Department of Chemistry, Miranda House, University of Delhi, Delhi, India
,
Martin Zoltnerj Drug Discovery and Evaluation Unit, Department of Parasitology, Faculty of Science, Charles University, BIOCEV, Vestec, Czech RepublicCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0002-0214-285X
ORCID Icon &
Brijesh Rathia Laboratory for Translational Chemistry and Drug Discovery, Department of Chemistry, Hansraj College, University of Delhi, Delhi, IndiaCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0003-2133-8847
ORCID Icon show all
Pages 10162-10180 | Received 05 Jan 2021, Accepted 03 Jun 2021, Published online: 21 Jun 2021

Citations (2)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Archana Chinnamadhu, Jaganathan Ramakrishnan, Suganya Suresh, Prakash Ramadurai & Kumaradhas Poomani. (2023) Dynamics and binding affinity of nucleoside and non-nucleoside inhibitors with RdRp of SARS-CoV-2: a molecular screening, docking, and molecular dynamics simulation study. Journal of Biomolecular Structure and Dynamics 41:20, pages 10396-10410.
Read now

Articles from other publishers (1)

Anjani, Sumit Kumar, Brijesh Rathi & Poonam. (2023) Recent updates on the biological efficacy of approved drugs and potent synthetic compounds against SARS-CoV-2. RSC Advances 13:6, pages 3677-3687.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.