Advanced search
Publication Cover
Journal of Biomolecular Structure and Dynamics Volume 41, 2023 - Issue 18
Journal homepage
531
Views
10
CrossRef citations to date
0
Altmetric
Research Articles

Design, synthesis and molecular docking and ADME studies of novel hydrazone derivatives for AChE inhibitory, BBB permeability and antioxidant effects

Derya Osmaniyea Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey;b Central Research Laboratory (MERLAB), Faculty of Pharmacy, Anadolu University, Eskişehir, TurkeyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-0499-436X
ORCID Icon,
Iqrar Ahmadc Division of Computer Aided Drug Design, Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Maharashtra, IndiaORCID Iconhttps://orcid.org/0000-0002-7697-9572
ORCID Icon,
Begüm Nurpelin Sağlıka Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey;b Central Research Laboratory (MERLAB), Faculty of Pharmacy, Anadolu University, Eskişehir, TurkeyORCID Iconhttps://orcid.org/0000-0002-0151-6266
ORCID Icon,
Serkan Leventa Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey;b Central Research Laboratory (MERLAB), Faculty of Pharmacy, Anadolu University, Eskişehir, TurkeyORCID Iconhttps://orcid.org/0000-0003-3692-163X
ORCID Icon,
Harun M. Patelc Division of Computer Aided Drug Design, Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Maharashtra, IndiaORCID Iconhttps://orcid.org/0000-0003-0920-1266
ORCID Icon,
Yusuf Ozkaya Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey;b Central Research Laboratory (MERLAB), Faculty of Pharmacy, Anadolu University, Eskişehir, TurkeyORCID Iconhttps://orcid.org/0000-0001-8815-153X
ORCID Icon &
Zafer Asım Kaplancıklıa Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, TurkeyORCID Iconhttps://orcid.org/0000-0003-2252-0923
ORCID Icon show all
Pages 9022-9038 | Received 02 Aug 2022, Accepted 19 Oct 2022, Published online: 03 Nov 2022

Citations (10)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (6)

Anindita Ash Prome, Tanjin Barketullah Robin, Nadim Ahmed, Nurul Amin Rani, Iqrar Ahmad, Harun Patel, Md. Nazmul Islam Bappy & Kazi Md. Ali Zinnah. (2023) A reverse docking approach to explore the anticancer potency of natural compounds by interfering metastasis and angiogenesis. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-16.
Read now
Ferdaus Mohd Altaf Hossain, Md. Nazmul Islam Bappy, Tanjin Barketullah Robin, Iqrar Ahmad, Harun Patel, Nusrat Jahan, Md Gulam Rabbany Rabbi, Anindita Roy, Wasima Chowdhury, Nadim Ahmed, Anindita Ash Prome, Nurul Amin Rani, Parvez Khan & Kazi Md. Ali Zinnah. (2023) A review on computational studies and bioinformatics analysis of potential drugs against monkeypox virus. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-17.
Read now
Youness El Bakri, Subramani Karthikeyan, Chin-Hung Lai, Etify A. Bakhite, Iqrar Ahmad, Abdu E. Abdel-Rahman, Suzan Abuelhassan, Islam S. Marae, Shaaban K. Mohamed & Joel T. Mague. (2023) New tetrahydroisoquinoline-4-carbonitrile derivatives as potent agents against cyclin-dependent kinases, crystal structures, and computational studies. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-19.
Read now
Youness El Bakri, Basharat Ahmad, Kandasamy Saravanan, Iqrar Ahmad, Etify A. Bakhite, Osama Younis, Safiyyah A. H. Al-Waleedy, Omaima F. Ibrahim, Ayman Nafady, Joel T. Mague & Shaaban K. Mohamed. (2023) Insight into crystal structures and identification of potential styrylthieno[2,3-b]pyridine-2-carboxamidederivatives against COVID-19 Mpro through structure-guided modeling and simulation approach. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-19.
Read now
Ajayrajsinh R. Zala, Dinesh Kumar, Uvais Razakhan, Dhanji P. Rajani, Iqrar Ahmad, Harun Patel & Premlata Kumari. (2023) Molecular modeling and biological investigation of novel s-triazine linked benzothiazole and coumarin hybrids as antimicrobial and antimycobacterial agents. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-12.
Read now
Nouha Bouali, Iqrar Ahmad, Harun Patel, Elham Bader Alhejaili, Walid Sabri Hamadou, Riadh Badraoui, Ramzi Hadj Lajimi, Mousa Alreshidi, Arif Jamal Siddiqui, Mohd Adnan, Mohammad A. Abdulhakeem, Abdulrahman S. Bazaid, Mitesh Patel, Mohd Saeed, Mejdi Snoussi & Emira Noumi. (2023) GC–MS screening of the phytochemical composition of Ziziphus honey: ADME properties and in vitro/in silico study of its antimicrobial activity. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-13.
Read now

Articles from other publishers (4)

Kajalben B. Patel, Dhanji Rajani, Iqrar Ahmad, Harun Patel, Hitesh D. Patel & Premlata Kumari. (2023) Chrysin based pyrimidine-piperazine hybrids: design, synthesis, in vitro antimicrobial and in silico E. coli topoisomerase II DNA gyrase efficacy. Molecular Diversity.
Crossref
Parth P. Patel, Navin B. Patel, Manesh S. Tople, Vatsal M. Patel, Iqrar Ahmed & Harun Patel. (2023) Microwave produced 8-methyl-1,2,4,8-tetraazaspiro[4.5]dec-2-en-3-amine derivatives: their in vitro and in silico analysis. Molecular Diversity.
Crossref
M. Li, X. -Y. Qiu, Z. -X. Zheng & Y. -J. Wu. (2023) SYNTHESIS, CHARACTERIZATION AND X-RAY CRYSTAL STRUCTURE OF N′-(3,5-DIFLUORO-2- HYDROXYBENZYLIDENE)-4-METHYLBENZOHYDRAZIDE AND ITS OXIDOVANADIUM(V) COMPLEX WITH ANTIBACTERIAL ACTIVITY. Journal of Structural Chemistry 64:2, pages 314-323.
Crossref
Ercan ÇINAR, Mehmet BOĞA, Giray TOPAL & Reşit ÇAKMAK. (2022) SOME NOVEL SCHIFF BASE DERIVATIVES AS PROMISING CHOLINESTERASE INHIBITORS WITH ANTIOXIDANT ACTIVITY AGAINST ALZHEIMER’S DISEASE: SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION. Middle East Journal of Science 8:2, pages 138-146.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.