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Sequential Analysis
Design Methods and Applications
Volume 14, 1995 - Issue 3
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Original Articles

Toxicity in sequential dose-response experiments

Nancy Flournoy Department of Mathematics and Statistics, The American University, Washington, DC 20016-8050
,
Stephen D. Durham Department of Statistics, The University of South Carolina, Columbia, SC 29208
&
William F. Rosenberger Department of Mathematics and Statistics, The University of Maryland, 5401 Wilkens Avenue, Baltimore, MD 21228-5398
Pages 217-227 | Published online: 29 Mar 2007

Citations (10)

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Read on this site (2)

Mario Stylianou. (2009) Derivation of Exact Distributions Following an Up-and-Down Design. Communications in Statistics - Theory and Methods 38:16-17, pages 3190-3197.
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E. E. Kpamegan & N. Flournoy. (2008) Up-and-Down Designs for Selecting the Dose with Maximum Success Probability. Sequential Analysis 27:1, pages 78-96.
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Articles from other publishers (8)

Oleksandr Sverdlov, Weng Kee Wong & Yevgen Ryeznik. (2014) Adaptive clinical trial designs for phase I cancer studies. Statistics Surveys 8:none.
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Misrak Gezmu & Nancy Flournoy. (2006) Group up-and-down designs for dose-finding. Journal of Statistical Planning and Inference 136:6, pages 1749-1764.
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William F. Rosenberger & Linda M. Haines. (2002) Competing designs for phase I clinical trials: a review. Statistics in Medicine 21:18, pages 2757-2770.
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Mario Stylianou & Nancy Flournoy. (2002) Dose Finding Using the Biased Coin Up-and-Down Design and Isotonic Regression. Biometrics 58:1, pages 171-177.
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Euloge E. Kpamegan & Nancy Flournoy. 2001. Optimum Design 2000. Optimum Design 2000 211 224 .
Janis Hardwick & Quentin F. Stout. 2001. Optimum Design 2000. Optimum Design 2000 195 210 .
S.D. Durham, N. Flournoy & W. Li. (2008) A sequential design for maximizing the probability of a favourable response. Canadian Journal of Statistics 26:3, pages 479-495.
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William F. Rosenberger. (1996) New directions in adaptive designs. Statistical Science 11:2.
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