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Annals of Medicine Volume 40, 2008 - Issue 6
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Review Article

Prolyl 4-hydroxylases, key enzymes in the synthesis of collagens and regulation of the response to hypoxia, and their roles as treatment targets

Dr Johanna Myllyharju Oulu Centre for cell-Matrix, Biocenter, Oulu, Finland; Department of Medical Biochemistry and Molecular Biology, University of Oulu, Oulu, Finland
Pages 402-417 | Received 29 Jan 2008, Published online: 08 Jul 2009

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Marialucia Gallorini & Simone Carradori. (2021) Understanding collagen interactions and their targeted regulation by novel drugs. Expert Opinion on Drug Discovery 16:11, pages 1239-1260.
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Kerstin Lippl, Anna Boleininger, Michael A McDonough, Martine I Abboud, Hanna Tarhonskaya, Rasheduzzaman Chowdhury, Christoph Loenarz & Christopher J Schofield. (2018) Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal Trichoplax adhaerens. Hypoxia 6, pages 57-71.
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Peter Ratcliffe, Peppi Koivunen, Johanna Myllyharju, Jiannis Ragoussis, Judith VMG Bovée, Ines Batinic-Haberle, Claire Vinatier, Valérie Trichet, Florence Robriquet, Lisa Oliver & Betty Gardie. (2017) Update on hypoxia-inducible factors and hydroxylases in oxygen regulatory pathways: from physiology to therapeutics. Hypoxia 5, pages 11-20.
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Vesa Anttila, Henri Haapanen, Fredrik Yannopoulos, Johanna Herajärvi, Tuomas Anttila & Tatu Juvonen. (2016) Review of remote ischemic preconditioning: from laboratory studies to clinical trials. Scandinavian Cardiovascular Journal 50:5-6, pages 355-361.
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Connie Wu, Jessica So, Brandi N. Davis-Dusenbery, Hank H. Qi, Donald B. Bloch, Yang Shi, Giorgio Lagna & Akiko Hata. (2011) Hypoxia Potentiates MicroRNA-Mediated Gene Silencing through Posttranslational Modification of Argonaute2. Molecular and Cellular Biology 31:23, pages 4760-4774.
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Hossein Heli, Siamak Mirtorabi & Khashayar Karimian. (2011) Advances in iron chelation: an update. Expert Opinion on Therapeutic Patents 21:6, pages 819-856.
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Kelly L. Gorres & Ronald T. Raines. (2010) Prolyl 4-hydroxylase. Critical Reviews in Biochemistry and Molecular Biology 45:2, pages 106-124.
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