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Blood Pressure Volume 26, 2017 - Issue 6
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Original Article

Results of a randomized controlled pilot trial of intravascular renal denervation for management of treatment-resistant hypertension

Lotte JacobsStudies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; View further author information
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Alexandre PersuDivision of Cardiology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium; ;Pole of Cardiovascular Research, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium; View further author information
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Qi-Fang HuangStudies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; View further author information
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Jean-Philippe LengeléDivision of Cardiology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium; ;Department of Nephrology, Grand Hôpital de Charleroi, Gilly, Belgium; View further author information
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Lutgarde ThijsStudies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; View further author information
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Frank HammerDivision of Radiology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium; View further author information
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Wen-Yi YangStudies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; View further author information
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Zhen-Yu ZhangStudies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; View further author information
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Jean RenkinDivision of Cardiology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium; ;Pole of Cardiovascular Research, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium; View further author information
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Peter SinnaeveDivision of Cardiology, University Hospitals Leuven, Leuven, Belgium; View further author information
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Fang-Fei WeiStudies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; View further author information
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Agnès PasquetDivision of Cardiology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium; ORCID Iconhttp://orcid.org/0000-0002-3778-6604View further author information
ORCID Icon,
Fadl Elmula M. Fadl ElmulaDepartment of Cardiology, Oslo University Hospital Ullevål, Oslo, Norway; View further author information
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Marc CarlierDepartment of Cardiology, Grand Hôpital de Charleroi, Gilly, Belgium; View further author information
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Arif ElvanDepartment of Cardiology, Isala Hospital, Zwolle, The Netherlands; View further author information
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Cora WunderDepartment of Forensic Toxicology, Institute of Legal Medicine, University of Frankfurt, Frankfurt, Germany; View further author information
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Sverre E. KjeldsenDepartment of Cardiology, Oslo University Hospital Ullevål, Oslo, Norway; View further author information
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Stefan W. ToennesDepartment of Forensic Toxicology, Institute of Legal Medicine, University of Frankfurt, Frankfurt, Germany; View further author information
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Stefan JanssensDivision of Cardiology, Department Internal Medicine, University Hospitals Leuven, Leuven, Belgium; View further author information
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Peter VerhammeDivision of Cardiology, Department Internal Medicine, University Hospitals Leuven, Leuven, Belgium; ;Centre for Molecular and Vascular Biology, Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; View further author information
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Jan A. StaessenStudies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; ;R&D Group VitaK, Maastricht University, Maastricht, The NetherlandsCorrespondence[email protected], [email protected]
ORCID Iconhttp://orcid.org/0000-0002-3026-1637View further author information
ORCID Icon & The European Network Coordinating Research on Renal Denervation show all
Pages 321-331 | Received 07 Apr 2017, Accepted 13 Apr 2017, Published online: 10 May 2017

Citations (20)

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Read on this site (3)

Tove Aminda Hanssen, Anna Subbotina, Atena Miroslawska, Marit Dahl Solbu & Terje Kristian Steigen. (2022) Quality of life following renal sympathetic denervation in treatment-resistant hypertensive patients: a two-year follow-up study. Scandinavian Cardiovascular Journal 56:1, pages 174-179.
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Alexandre Persu, Frédéric Maes, Stefan W. Toennes, Sabrina Ritscher, Coralie Georges, Pierre Wallemacq, Nicole Haratani, Helen Parise, Tim A. Fischell, Lucas Lauder & Felix Mahfoud. (2022) Impact of drug adherence on blood pressure response to alcohol-mediated renal denervation. Blood Pressure 31:1, pages 109-117.
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Cora Wunder, Alexandre Persu, Jean-Philippe Lengelé, Coralie MG Georges, Jean Renkin, Agnès Pasquet, Marc Carlier, Zhen-Yu Zhang & Jan A. Staessen. (2019) Adherence to antihypertensive drug treatment in patients with apparently treatment-resistant hypertension in the INSPiRED pilot study. Blood Pressure 28:3, pages 168-172.
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Articles from other publishers (17)

Hata Mujadzic, Neil D Mehta, Sean J Battle & Donald J DiPette. (2023) Editorial commentary: Renal denervation for hypertension: A new meta-analysis promotes further discussion. Trends in Cardiovascular Medicine 33:8, pages 499-501.
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Gabrielle Bourque, Julius Vladimir Ilin, Marcel Ruzicka, Gregory L Hundemer, Risa Shorr & Swapnil Hiremath. (2023) Nonadherence Is Common in Patients With Apparent Resistant Hypertension: A Systematic Review and Meta-analysis. American Journal of Hypertension 36:7, pages 394-403.
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Anna Pisano, Luigi Francesco Iannone, Antonio Leo, Emilio Russo, Giuseppe Coppolino & Davide Bolignano. (2021) Renal denervation for resistant hypertension. Cochrane Database of Systematic Reviews 2021:11.
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Jonathan Silverwatch, Kristen E. Marti, Mi T. Phan, Hinali Amin, Yuani M. Roman, Vinay Pasupuleti, Maciej Banach, Joshuan J. Barboza & Adrian V. Hernandez. (2021) Renal Denervation for Uncontrolled and Resistant Hypertension: Systematic Review and Network Meta-Analysis of Randomized Trials. Journal of Clinical Medicine 10:4, pages 782.
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Lucas Lauder, Michel Azizi, Ajay J. Kirtane, Michael Böhm & Felix Mahfoud. (2020) Device-based therapies for arterial hypertension. Nature Reviews Cardiology 17:10, pages 614-628.
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David Richter, Miloš Táborský, Marián Fedorco, David Vindiš, Jan Václavík, Eva Kociánová, Marie Lazárová, Jiří Ostřanský, Martin Sluka, Radomír Nykl, Miloš Špaček & Rostislav Stříbrný. (2019) Renal denervation in the treatment of resistant hypertension: a new dawn?. Intervenční a akutní kardiologie 18:3, pages 143-148.
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Zhen-Yu ZhangWen-Yi YangAnna F. DominiczakJi-Guang WangYing WuBader AlmustafaSiew Mooi ChingYan LiVarahabhatla VamsiMichael BursztynQiuyan DaiShaowen LiuJan A. Staessen. (2019) Diagnosis and Management of Resistant Hypertension. Hypertension 74:5, pages 1064-1067.
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Vasilios Papademetriou, Konstantinos Stavropoulos, Kostas Imprialos, Michael Doumas, Roland E. Schmieder, Atul Pathak & Costas Tsioufis. (2019) New data, new studies, new hopes for renal denervation in patients with uncontrolled hypertension. International Journal of Cardiology Hypertension 3, pages 100022.
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Melvin D Lobo, Andrew S P Sharp, Vikas Kapil, Justin Davies, Mark A de Belder, Trevor Cleveland, Clare Bent, Neil Chapman, Indranil Dasgupta, Terry Levy, Anthony Mathur, Matthew Matson, Manish Saxena & Francesco P Cappuccio. (2019) Joint UK societies’ 2019 consensus statement on renal denervation. Heart 105:19, pages 1456-1463.
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Xiaocheng Cheng, Dongying Zhang, Suxin Luo & Shu Qin. (2019) Effect of Catheter-Based Renal Denervation on Uncontrolled Hypertension: A Systematic Review and Meta-analysis. Mayo Clinic Proceedings 94:9, pages 1695-1706.
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Jan Kvasnička, Lukáš Lambert, Petr Waldauf, Tomáš Zelinka, Ondřej Petrák, Branislav Štrauch, Robert Holaj, Tomáš Indra, Zuzana Krátká, Judita Klímová, Jan Václavík, Eva Kociánová, Igor Nykl, Otakar Jiravský, Gabriela Rappová, Miloš Táborský, Marian Branny, Jiří Widimský & Ján Rosa. (2019) (Prediction of long-term renal denervation efficacy). Cor et Vasa 61:4, pages e378-e384.
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Michael A. Weber, Felix Mahfoud, Roland E. Schmieder, David E. Kandzari, Konstantinos P. Tsioufis, Raymond R. Townsend, Kazuomi Kario, Michael Böhm, Andrew S.P. Sharp, Justin E. Davies, John W. Osborn, Greg D. Fink, David E. Euler, Debbie L. Cohen, Markus P. Schlaich & Murray D. Esler. (2019) Renal Denervation for Treating Hypertension. JACC: Cardiovascular Interventions 12:12, pages 1095-1105.
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Pradyumna Agasthi, Justin Shipman, Reza Arsanjani, Moses Ashukem, Marlene. E. Girardo, Charan Yerasi, Nithin. R. Venepally, Floyd David Fortuin & Farouk Mookadam. (2019) Renal Denervation for Resistant Hypertension in the contemporary era: A Systematic Review and Meta-analysis. Scientific Reports 9:1.
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Marshall J Heradien, Pieter van der Bijl & Paul A Brink. (2019) Renal Denervation in High-risk Patients with Hypertension. Heart International 13:2, pages 12.
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Reetu R. SinghKate M. Denton. (2018) Renal Denervation. Hypertension 72:3, pages 528-536.
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Fang-Fei Wei, Zhen-Yu Zhang, Qi-Fang Huang & Jan A. Staessen. (2018) Diagnosis and management of resistant hypertension: state of the art. Nature Reviews Nephrology 14:7, pages 428-441.
Crossref
Wen-Yi Yang, Blerim Mujaj, Ljupcho Efremov, Zhen-Yu Zhang, Lutgarde Thijs, Fang-Fei Wei, Qi-Fang Huang, Aernout Luttun, Peter Verhamme, Tim S Nawrot, José Boggia & Jan A Staessen. (2018) ECG Voltage in Relation to Peripheral and Central Ambulatory Blood Pressure. American Journal of Hypertension 31:2, pages 178-187.
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