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Renal Failure Volume 29, 2007 - Issue 4
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Laboratory Study

Effects of Ficus thonningii (Blume) [Morarceae] Stem-Bark Ethanolic Extract on Blood Glucose, Cardiovascular and Kidney Functions of Rats, and on Kidney Cell Lines of the Proximal (LLC-PK1) and Distal Tubules (MDBK)

C.T. Musabayane Discipline of Human Physiology, Faculty of Health Sciences, University of KwaZulu-Natal, Durban, South AfricaCorrespondence[email protected] [email protected]
,
M. Gondwe Discipline of Human Physiology, Faculty of Health Sciences, University of KwaZulu-Natal, Durban, South Africa
,
D.R. Kamadyaapa Discipline of Human Physiology, Faculty of Health Sciences, University of KwaZulu-Natal, Durban, South Africa
,
A.A. Chuturgoon Discipline of Medical Biochemistry, Faculty of Health Sciences, University of KwaZulu-Natal, Durban, South Africa
&
J.A.O. Ojewole Discipline of Pharmacology, Faculty of Health Sciences, University of KwaZulu-Natal, Durban, South Africa
Pages 389-397 | Published online: 07 Jul 2009

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C.T. Musabayane, M.A. Tufts & R.F. Mapanga. (2010) Synergistic antihyperglycemic effects between plant-derived oleanolic acid and insulin in streptozotocin-induced diabetic rats. Renal Failure 32:7, pages 832-839.
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R. F. Mapanga & C. T. Musabayane. (2010) The Renal Effects of Blood Glucose-Lowering Plant-Derived Extracts in Diabetes Mellitus—an Overview. Renal Failure 32:1, pages 132-138.
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R. F. Mapanga, M. A. Tufts, F. O. Shode & C. T. Musabayane. (2009) Renal Effects of Plant-Derived Oleanolic Acid in Streptozotocin-Induced Diabetic Rats. Renal Failure 31:6, pages 481-491.
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Jamilu B. Danjuma, Ibrahim B. Abubakar, Jude Nwaogu, Aliyu MuhamamdIbrahim MalamiAbubakar Abdulhamid. (2022) Ethnomedicinal study and in vitro validation of medicinal plants used for treating Jaundice in Zuru emirate of Kebbi State, Nigeria. Annals of Science and Technology 7:2, pages 29-40.
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T Wulandari, T Wiyoko, M Hakiki, Z R Habibie & T W Agrita. (2022) Persea Americana Mill Extraction as Antibacteria. IOP Conference Series: Earth and Environmental Science 1030:1, pages 012004.
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Aanchal Bansal & Chinmayee Priyadarsini. 2022. Natural Drugs from Plants. Natural Drugs from Plants.
Olufunke Florence Ajeigbe, Ganiyu Oboh & Ayokunle Olubode Ademosun. (2021) Ficus plants in the Co-management of Hypertension and Erectile dysfunction. Phytomedicine Plus 1:3, pages 100096.
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A. O. Ojetunde. (2021) ANTIDIABETIC EFFECTS OF MEDICINAL PLANTS. Eastern Ukrainian Medical Journal 9:1, pages 1-17.
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Sadegh Shabab, Zahra Gholamnezhad & Maryam Mahmoudabady. (2021) Protective effects of medicinal plant against diabetes induced cardiac disorder: A review. Journal of Ethnopharmacology 265, pages 113328.
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Trevor T. Nyakudya, Thulani Tshabalala, Rachael Dangarembizi, Kennedy H. Erlwanger & Ashwell R. Ndhlala. (2020) The Potential Therapeutic Value of Medicinal Plants in the Management of Metabolic Disorders. Molecules 25:11, pages 2669.
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Coker Morenike, Akanji Veronica, Benjamin O. Emikpe, Victor O. Oyebanji & Theophilus A. Jarikre. (2019) Investigations on the antimicrobial and wound healing activity of Ficus thonningii Blume extracts. Comparative Clinical Pathology 28:4, pages 1113-1118.
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Yinxian Shi, Aye Mya Mon, Yao Fu, Yu Zhang, Chen Wang, Xuefei Yang & Yuhua Wang. (2018) The genus Ficus (Moraceae) used in diet: Its plant diversity, distribution, traditional uses and ethnopharmacological importance. Journal of Ethnopharmacology 226, pages 185-196.
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Ponnuvel Deepa, Kandhasamy Sowndhararajan, Songmun Kim & Se Jin Park. (2018) A role of Ficus species in the management of diabetes mellitus: A review. Journal of Ethnopharmacology 215, pages 210-232.
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Happiness P. Sibiya, Musa V. Mabandla & Cephas T. Musabayane. (2016) The Effects of Transdermally Delivered Oleanolic Acid on Malaria Parasites and Blood Glucose Homeostasis in P. berghei-Infected Male Sprague-Dawley Rats. PLOS ONE 11:12, pages e0167132.
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Hlengiwe Pretty Madlala, Fanie Retief Van Heerden, Kanigula Mubagwa & Cephas Tagumirwa Musabayane. (2015) Changes in Renal Function and Oxidative Status Associated with the Hypotensive Effects of Oleanolic Acid and Related Synthetic Derivatives in Experimental Animals. PLOS ONE 10:6, pages e0128192.
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Oyinlola O Olaokun, Lyndy J McGaw, Maurice D Awouafack, Jacobus N Eloff & Vinny Naidoo. (2014) The potential role of GLUT4 transporters and insulin receptors in the hypoglycaemic activity of Ficus lutea acetone leaf extract. BMC Complementary and Alternative Medicine 14:1.
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Udoamaka F. Ezuruike & Jose M. Prieto. (2014) The use of plants in the traditional management of diabetes in Nigeria: Pharmacological and toxicological considerations. Journal of Ethnopharmacology 155:2, pages 857-924.
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Silindile I. Hadebe, Phikelelani S. Ngubane, Metse R. Serumula & Cephas T. Musabayane. (2014) Transdermal Delivery of Insulin by Amidated Pectin Hydrogel Matrix Patch in Streptozotocin-Induced Diabetic Rats: Effects on Some Selected Metabolic Parameters. PLoS ONE 9:7, pages e101461.
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Oyinlola O Olaokun, Lyndy J McGaw, Jacobus N Eloff & Vinny Naidoo. (2013) Evaluation of the inhibition of carbohydrate hydrolysing enzymes, antioxidant activity and polyphenolic content of extracts of ten African Ficus species (Moraceae) used traditionally to treat diabetes. BMC Complementary and Alternative Medicine 13:1.
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M. Gondwe, D.R. Kamadyaapa, M. Tufts, A.A. Chuturgoon & C.T. Musabayane. (2008) Sclerocarya birrea [(A. Rich.) Hochst.] [Anacardiaceae] stem-bark ethanolic extract (SBE) modulates blood glucose, glomerular filtration rate (GFR) and mean arterial blood pressure (MAP) of STZ-induced diabetic rats. Phytomedicine 15:9, pages 699-709.
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