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CRANIO®
The Journal of Craniomandibular & Sleep Practice
Volume 39, 2021 - Issue 2
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Rehabilitative Medicine

Evaluation of the efficacy of a new low-level laser therapy home protocol in the treatment of temporomandibular joint disorder-related pain: A randomized, double-blind, placebo-controlled clinical trial

Alessandro Del Vecchioa COU Oral Pathology and Medicine, Department of Oral and Maxillo Facial Sciences Sapienza, University of Rome, Rome, ItalyCorrespondence[email protected]
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, DDS, PhD,
Miriam Floravantia COU Oral Pathology and Medicine, Department of Oral and Maxillo Facial Sciences Sapienza, University of Rome, Rome, ItalyView further author information
, DDS,
Armando Boccassinib Department of TMJ Dysfunction, Department of Oral and Maxillo Facial Sciences Sapienza, University of Rome, Rome, ItalyView further author information
, DDS,
Gianfranco Gaimaria COU Oral Pathology and Medicine, Department of Oral and Maxillo Facial Sciences Sapienza, University of Rome, Rome, ItalyView further author information
, DDS,
Annarita Vestric Department of Public Health and Infectious Diseases, Policlinic Umberto I Rome, Rome, ItalyView further author information
, MD,
Carlo Di Paolob Department of TMJ Dysfunction, Department of Oral and Maxillo Facial Sciences Sapienza, University of Rome, Rome, ItalyView further author information
, MD &
Umberto Romeoa COU Oral Pathology and Medicine, Department of Oral and Maxillo Facial Sciences Sapienza, University of Rome, Rome, ItalyView further author information
, DDS show all
Pages 141-150 | Published online: 19 Apr 2019

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Martina Ferrillo, Ludovica Nucci, Amerigo Giudice, Dario Calafiore, Nicola Marotta, Giuseppe Minervini, Fabrizia d’Apuzzo, Antonio Ammendolia, Letizia Perillo & Alessandro de Sire. (2022) Efficacy of conservative approaches on pain relief in patients with temporomandibular joint disorders: a systematic review with network meta-analysis. CRANIO® 0:0, pages 1-17.
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Roberta Bertolli da Silveira, Izabela Ferreira, André Luis Botelho & Andréa Cândido Dos Reis. (2022) Effect of photobiomodulation treatment on pain control in patients with temporomandibular dysfunction disorder: systematic review. CRANIO® 0:0, pages 1-11.
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Articles from other publishers (18)

Magdalena Gębska, Bartosz Dalewski, Łukasz Pałka, Paweł Kiczmer & Łukasz Kołodziej. (2023) Effect of physiotherapeutic procedures on the bioelectric activity of the masseter muscle and the range of motion of the temporomandibular joints in the female population with chronic pain: a randomized controlled trial. BMC Oral Health 23:1.
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Rabie Abufoul, Lilach Gavish & Marwan Haddad. (2023) Photobiomodulation self‐treatment at home after rotator cuff arthroscopic repair accelerates improvement in pain, functionality, and quality of life: A double‐blind, sham‐controlled, randomized clinical trial. Lasers in Surgery and Medicine 55:7, pages 662-673.
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Yan Zhang, Yingqiu Qian, Kangxin Huo, Jingxin Liu, Xi Huang & Jie Bao. (2023) Efficacy of laser therapy for temporomandibular disorders: A systematic review and meta-analysis. Complementary Therapies in Medicine 74, pages 102945.
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Amira A. M. M. Attia & Sally S. Awad. (2023) Hyaluronic Acid and Platelet-Rich Plasma Mixture Versus Hyaluronic Acid and Corticosteroid in the Treatment of Temporomandibular Joint Internal Derangement: A Comparative Randomized Study. Journal of Maxillofacial and Oral Surgery.
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Noha H. El‐Shaheed, Aisha Z. H. Mostafa & Marwa A. Aboelez. (2023) Efficacy of stabilisation splint and low‐level laser therapy for patients with chronic closed lock from non‐reducible displaced temporo‐mandibular joint discs: A parallel randomised clinical trial. Journal of Oral Rehabilitation 50:3, pages 177-193.
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Liliana Argueta-Figueroa, Luis Angel Flores-Mejía, Beatriz Xóchitl Ávila-Curiel, Blanca Irma Flores-Ferreyra & Rafael Torres-Rosas. (2022) Nonpharmacological Interventions for Pain in Patients with Temporomandibular Joint Disorders: A Systematic Review. European Journal of Dentistry 16:03, pages 500-513.
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Amir Haze, Lilach Gavish, Ofer Elishoov, Dorit Shorka, Tamir Tsohar, Yechiel N. Gellman & Meir Liebergall. (2021) Treatment of diabetic foot ulcers in a frail population with severe co-morbidities using at-home photobiomodulation laser therapy: a double-blind, randomized, sham-controlled pilot clinical study. Lasers in Medical Science 37:2, pages 919-928.
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Hui Ren, Jingying Liu, Yang Liu, Caiyun Yu, Guangjie Bao & Hong Kang. (2021) Comparative effectiveness of low‐level laser therapy with different wavelengths and transcutaneous electric nerve stimulation in the treatment of pain caused by temporomandibular disorders: A systematic review and network meta‐analysis. Journal of Oral Rehabilitation 49:2, pages 138-149.
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Alessandro Del Vecchio, Gianluca Tenore, Daniele Pergolini, Federica Rocchetti, Gaspare Palaia & Umberto Romeo. (2022) The Role of the Laser Photobiomodulation (PBM) in the Management of Patients at Risk or Affected by MRONJ. Oral 2:1, pages 7-15.
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Nuonuo Cong, Ning Wang, Shengyuan Huang, Taiqi Cheng & Xing Yan. (2021) Diagnostic significance of magnetic resonance imaging in distinguishing temporomandibular disorders: a retrospective chart review. BMC Oral Health 21:1.
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Keunhyo Lee & Seungchul Chon. (2021) Assessments of Muscle Thickness and Tonicity of the Masseter and Sternocleidomastoid Muscles and Maximum Mouth Opening in Patients with Temporomandibular Disorder. Healthcare 9:12, pages 1640.
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Gaspare Palaia, Federico Renzi, Daniele Pergolini, Alessandro Del Vecchio, Paolo Visca, Gianluca Tenore & Umberto Romeo. (2021) Histological Ex Vivo Evaluation of the Suitability of a 976 nm Diode Laser in Oral Soft Tissue Biopsies. International Journal of Dentistry 2021, pages 1-6.
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Farid Abbasi, Ali Moaddabi, Ghazal Beithardan, Mohammad Asnaashari, SeyedeFateme Rezaei & Amirhossein Moaddabi. (2021) Comparing the Effects of Low-Level Laser Therapy with Ibuprofen in Improving Myofascial Pain Dysfunction Syndrome. Dental Hypotheses 12:3, pages 124.
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Greice de Brito BitencourtLara Jansiski MottaDaniela de Fátima Teixeira da SilvaKarina Helga Leal TurcioRavana Angelini SfalcinAdrielle Mendes de Paula GomesRaquel Agnelli Mesquita-FerrariKristianne Porta Santos FernandesAldo Brugnera JúniorSandra Kalil Bussadori. (2021) Evaluation of the Preventive Effect of Photobiomodulation on Orofacial Discomfort in Dental Procedures: A Randomized-Controlled, Crossover Study and Clinical Trial. Photobiomodulation, Photomedicine, and Laser Surgery 39:1, pages 38-45.
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Emanuela Serritella, Giordano Scialanca, Paola Di Giacomo & Carlo Di Paolo. (2020) Local Vibratory Stimulation for Temporomandibular Disorder Myofascial Pain Treatment: A Randomised, Double-Blind, Placebo-Controlled Preliminary Study. Pain Research and Management 2020, pages 1-7.
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Abdalwhab Zwiri, Manal Ahmad Alrawashdeh, Mohammad Khan, Wan Muhamad Amir W. Ahmad, Nur Karyatee Kassim, Jawaad Ahmed Asif, Khoo Suan Phaik, Adam Husein & Zuryati Ab-Ghani. (2020) Effectiveness of the Laser Application in Temporomandibular Joint Disorder: A Systematic Review of 1172 Patients. Pain Research and Management 2020, pages 1-10.
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Luís MonteiroRaquel FerreiraTiago ResendeJosé Júlio PachecoFilomena Salazar. (2020) Effectiveness of Photobiomodulation in Temporomandibular Disorder-Related Pain Using a 635 nm Diode Laser: A Randomized, Blinded, and Placebo-Controlled Clinical Trial. Photobiomodulation, Photomedicine, and Laser Surgery 38:5, pages 280-288.
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Bruno Macedo De Sousa, Nansi López-Valverde, Antonio López-Valverde, Francisco Caramelo, Javier Flores Fraile, Julio Herrero Payo & María João Rodrigues. (2020) Different Treatments in Patients with Temporomandibular Joint Disorders: A Comparative Randomized Study. Medicina 56:3, pages 113.
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