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Biofouling
The Journal of Bioadhesion and Biofilm Research
Volume 33, 2017 - Issue 10
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Original Articles

KR-12-a5 is a non-cytotoxic agent with potent antimicrobial effects against oral pathogens

Karina Sampaio CaiaffaSão Paulo State University (UNESP), Department of Restorative Dentistry, School of Dentistry, Araçatuba, BrazilORCID Iconhttp://orcid.org/0000-0002-8159-727X
ORCID Icon,
Loiane MassunariSão Paulo State University (UNESP), Department of Restorative Dentistry, School of Dentistry, Araçatuba, BrazilORCID Iconhttp://orcid.org/0000-0001-5626-7087
ORCID Icon,
Marcelle DanelonSão Paulo State University (UNESP), Department of Pediatric Dentistry and Public Health, School of Dentistry, Araçatuba, BrazilORCID Iconhttp://orcid.org/0000-0003-2091-649X
ORCID Icon,
Gabriel Flores AbunaUniversity of Campinas (UNICAMP), Department of Restorative Dentistry, School of Dentistry, Piracicaba, BrazilORCID Iconhttp://orcid.org/0000-0002-9812-4882
ORCID Icon,
Telma Blanca Lombardo BedranSão Paulo State University (UNESP), Department of Physiology and Pathology, School of Dentistry, Araraquara, BrazilORCID Iconhttp://orcid.org/0000-0002-3579-6147
ORCID Icon,
Norival Alves Santos-FilhoSão Paulo State University (UNESP), Department of Biochemistry and Chemical Technology, Institute of Chemistry, Araraquara, BrazilORCID Iconhttp://orcid.org/0000-0002-0344-6900
ORCID Icon,
Denise Madalena Palomari SpolidorioSão Paulo State University (UNESP), Department of Physiology and Pathology, School of Dentistry, Araraquara, BrazilORCID Iconhttp://orcid.org/0000-0003-2376-1024
ORCID Icon,
Natalia Leal VizotoUniversity of Campinas (UNICAMP), Department of Oral Diagnosis, School of Dentistry, Piracicaba, BrazilORCID Iconhttp://orcid.org/0000-0002-9307-3502
ORCID Icon,
Eduardo Maffud CilliSão Paulo State University (UNESP), Department of Biochemistry and Chemical Technology, Institute of Chemistry, Araraquara, BrazilORCID Iconhttp://orcid.org/0000-0002-4767-0904
ORCID Icon &
Cristiane DuqueSão Paulo State University (UNESP), Department of Pediatric Dentistry and Public Health, School of Dentistry, Araçatuba, BrazilCorrespondence[email protected]
[email protected]
ORCID Iconhttp://orcid.org/0000-0002-2575-279X
ORCID Icon show all
Pages 807-818 | Received 13 Nov 2016, Accepted 17 Aug 2017, Published online: 12 Oct 2017

Citations (18)

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Vanessa Rodrigues Dos Santos, Karina Sampaio Caiaffa, Warlley Campos de Oliveira, Jesse Augusto Pereira, Gabriel Flores Abuna, Carlos Roberto Polaquini, Luís Octávio Regasini, Aimée Maria Guiotti & Cristiane Duque. (2021) Cytotoxicity and effects of curcumin and cinnamaldehyde hybrids on biofilms of oral pathogens . Biofouling 37:6, pages 591-605.
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Articles from other publishers (17)

Gina P. Rodríguez-Castaño, Frank Rosenau, Ludger Ständker & Carolina Firacative. (2023) Antimicrobial Peptides: Avant-Garde Antifungal Agents to Fight against Medically Important Candida Species. Pharmaceutics 15:3, pages 789.
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Raiyyan Aftab, Vikash H. Dodhia, Christopher Jeanes & Ryckie G. Wade. (2023) Bacterial sensitivity to chlorhexidine and povidone-iodine antiseptics over time: a systematic review and meta-analysis of human-derived data. Scientific Reports 13:1.
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Cristiane DUQUE, Amanda Caselato Andolfatto SOUZA, Kelly Limi AIDA, Jesse Augusto PEREIRA, Karina Sampaio CAIAFFA, Vanessa Rodrigues dos SANTOS, Leopoldo COSME-SILVA & Anuradha PRAKKI. (2023) Synergistic antimicrobial potential of EGCG and fosfomycin against biofilms associated with endodontic infections. Journal of Applied Oral Science 31.
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Gabriela Pacheco de Almeida Braga, Karina Sampaio Caiaffa, Jesse Augusto Pereira, Vanessa Rodrigues dos Santos, Amanda Caselato Andolfatto Souza, Lucas da Silva Ribeiro, Emerson Rodrigues Camargo, Anuradha Prakki & Cristiane Duque. (2022) Microbiological Properties and Cytotoxicity of PNVCL Hydrogels Containing Flavonoids as Intracanal Medication for Endodontic Therapy. Journal of Functional Biomaterials 13:4, pages 305.
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Arwa M. Abd-Elaziz, Hala M. Aly, Nashwa M. Saleh, Sawsan A. Fouad, Abla A. Ismail & Amr Fouda. (2021) Synthesis and characterization of the novel pyrimidine’s derivatives, as a promising tool for antimicrobial agent and in-vitro cytotoxicity. Journal of the Iranian Chemical Society 19:6, pages 2279-2296.
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John Yun Niu, Iris Xiaoxue Yin, William Ka Kei Wu, Quan-Li Li, May Lei Mei & Chun Hung Chu. (2021) Efficacy of the dual-action GA-KR12 peptide for remineralising initial enamel caries: an in vitro study. Clinical Oral Investigations 26:3, pages 2441-2451.
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Jesse Augusto Pereira, Carlos Roberto Polaquini, VanessaRodrigues dos Santos, Karina Sampaio Caiaffa, Rafaela Laruzo Rabelo, Reinaldo dos Santos Theodoro, Letícia Helena Theodoro, Luis Octavio Regasini & Cristiane Duque. (2021) Antibiofilm and cytotoxic effect of 3,3′-dihydroxycurcumin (DHC) as photosensitizer agent in antimicrobial photodynamic therapy for endodontic purposes. Photodiagnosis and Photodynamic Therapy 36, pages 102534.
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Karina Sampaio Caiaffa, Vanessa Rodrigues dos Santos, Gabriel Flores Abuna, Norival Alves Santos-Filho, Eduardo Maffud Cilli, Vivien Thiemy Sakai, Luciano Tavares Angelo Cintra & Cristiane Duque. (2021) Cytocompatibility and Synergy of EGCG and Cationic Peptides Against Bacteria Related to Endodontic Infections, in Planktonic and Biofilm Conditions. Probiotics and Antimicrobial Proteins 13:6, pages 1808-1819.
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I.M. Assane, N.A. Santos‐Filho, E.L. Sousa, M.C.O. Arruda Brasil, E.M. Cilli & F. Pilarski. (2021) Cytotoxicity and antimicrobial activity of synthetic peptides alone or in combination with conventional antimicrobials against fish pathogenic bacteria. Journal of Applied Microbiology 131:4, pages 1762-1774.
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John Yun Niu, Iris Xiaoxue Yin, William Ka Kei Wu, Quan-Li Li, May Lei Mei & Chun Hung Chu. (2021) Remineralising dentine caries using an artificial antimicrobial peptide: An in vitro study. Journal of Dentistry 111, pages 103736.
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John Yun Niu, Iris Xiaoxue Yin, William Ka Kei Wu, Quan-Li Li, May Lei Mei & Chun Hung Chu. (2021) A novel dual-action antimicrobial peptide for caries management. Journal of Dentistry 111, pages 103729.
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Kylen E. Ridyard & Joerg Overhage. (2021) The Potential of Human Peptide LL-37 as an Antimicrobial and Anti-Biofilm Agent. Antibiotics 10:6, pages 650.
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Jayaram Lakshmaiah Narayana, Biswajit Mishra, Tamara Lushnikova, Radha M. Golla & Guangshun Wang. (2019) Modulation of antimicrobial potency of human cathelicidin peptides against the ESKAPE pathogens and in vivo efficacy in a murine catheter-associated biofilm model. Biochimica et Biophysica Acta (BBA) - Biomembranes 1861:9, pages 1592-1602.
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Yassir Lekbach, Zhong Li, Dake Xu, Soumya El Abed, Yuqiao Dong, Dan Liu, Tingyue Gu, Saad Ibnsouda Koraichi, Ke Yang & Fuhui Wang. (2019) Salvia officinalis extract mitigates the microbiologically influenced corrosion of 304L stainless steel by Pseudomonas aeruginosa biofilm. Bioelectrochemistry 128, pages 193-203.
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Karina S. Caiaffa, Fernanda G. Basso, Norival A. Santos-Filho, Carlos Alberto de Souza-Costa, Vivien T. Sakai, Eduardo M. Cilli & Cristiane Duque. (2019) Effect of analogues of cationic peptides on dentin mineralization markers in odontoblast-like cells. Archives of Oral Biology 103, pages 19-25.
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Guangshun Wang, Jayaram Lakshmaiah Narayana, Biswajit Mishra, Yingxia Zhang, Fangyu Wang, Chunfeng Wang, D. Zarena, Tamara Lushnikova & Xiuqing Wang. 2019. Antimicrobial Peptides. Antimicrobial Peptides 215 240 .
Thais de Cássia Negrini, Hyun Koo & Rodrigo Alex Arthur. 2019. Oral Mucosal Immunity and Microbiome. Oral Mucosal Immunity and Microbiome 119 141 .

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