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Journal of Investigative Surgery Volume 22, 2009 - Issue 4
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ORIGINAL RESEARCH

The Effects of Cyclooxygenase (COX)-2 Inhibition on Ischemia-Reperfusion Injury in Liver Transplantation

Kiyohiro Oshima Intensive Care Unit, Gunma University Hospital, Showa-machi, Maebashi, Gunma, Japan
, MD,
Yoshihiro Yabata Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Showa-machi, Maebashi, Gunma, Japan
, MD,
Daisuke Yoshinari Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Showa-machi, Maebashi, Gunma, Japan
, MD &
Izumi Takeyoshi Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Showa-machi, Maebashi, Gunma, Japan
, MD
Pages 239-245 | Published online: 09 Sep 2009

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Orhan Cimen, Hüseyin Eken, Ferda Keskin Cimen, Asli Ozbek Bilgin, Kamil Pehlivanoglu, Eray Kurnaz, Mine Gülaboglu, Bahadir Suleyman & Halis Suleyman. (2019) Benidipine can prevent liver ischemia reperfusion injury in rats: a biochemical and histopathological evaluation. Biotechnology & Biotechnological Equipment 33:1, pages 1645-1652.
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Yu Jin Jeon, Hyoung Seok Kim, Kyung-Sik Song, Ho Jae Han, Soo Hyun Park, Woochul Chang & Min Young Lee. (2015) Protective effect of dieckol against chemical hypoxia-induced cytotoxicity in primary cultured mouse hepatocytes. Drug and Chemical Toxicology 38:2, pages 180-187.
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Rutong Ren, Tian Wang, Na Jiang, Tongshen Liu, Yuan Du, Chong Li, Leiming Zhang & Fenghua Fu. (2010) Protective effects of Danshensu on liver injury induced by omethoate in rats. Toxicology Mechanisms and Methods 20:8, pages 510-514.
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Articles from other publishers (12)

Heena Khan, Kunal Sharma, Amit Kumar, Amarjot Kaur & Thakur Gurjeet Singh. (2022) Therapeutic implications of cyclooxygenase (COX) inhibitors in ischemic injury. Inflammation Research 71:3, pages 277-292.
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María de Luján Alvarez & Florencia Lorenzetti. (2021) Role of eicosanoids in liver repair, regeneration and cancer. Biochemical Pharmacology 192, pages 114732.
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Seham A. Abdel-Gaber, Mohamed A. Ibrahim, Entesar F. Amin, Salwa A. Ibrahim, Rehab K. Mohammed & Aly M. Abdelrahman. (2015) Effect of selective versus non-selective cyclooxygenase inhibitors on ischemia–reperfusion-induced hepatic injury in rats. Life Sciences 134, pages 42-48.
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Kenya Yamanaka, Philipp Houben, Helge Bruns, Daniel Schultze, Etsuro Hatano & Peter Schemmer. (2015) A Systematic Review of Pharmacological Treatment Options Used to Reduce Ischemia Reperfusion Injury in Rat Liver Transplantation. PLOS ONE 10:4, pages e0122214.
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Mohamed A. Ibrahim, Seham A. Abdel-Gaber, Entesar F. Amin, Salwa A. Ibrahim, Rehab K. Mohammed & Aly M. Abdelrahman. (2014) Molecular mechanisms contributing to the protective effect of levosimendan in liver ischemia-reperfusion injury. European Journal of Pharmacology 741, pages 64-73.
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Yu Jin Jeon, Kyung Sik Song, Ho Jae Han, Soo Hyun Park, Woochul Chang & Min Young Lee. (2013) Rosmarinic acid inhibits chemical hypoxia-induced cytotoxicity in primary cultured rat hepatocytes. Archives of Pharmacal Research 37:7, pages 907-915.
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Sergio Duarte, Hiroyuki Kato, Naohisa Kuriyama, Kathryn Suko, Tomo-o Ishikawa, Ronald W. Busuttil, Harvey R. Herschman & Ana J. Coito. (2014) Hepatic Ischemia and Reperfusion Injury in the Absence of Myeloid Cell-Derived COX-2 in Mice. PLoS ONE 9:5, pages e96913.
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René H. Tolba, Ngwi Fet, Kei Yonezawa, Kojiro Taura, Akio Nakajima, Koichiro Hata, Yusuke Okamura, Hiroshi Uchinami, Uwe Klinge, Thomas Minor, Yoshio Yamaoka & Yuzo Yamamoto. (2014) Role of Preferential Cyclooxygenase-2 Inhibition by Meloxicam in Ischemia/Reperfusion Injury of the Rat Liver. European Surgical Research 53:1-4, pages 11-24.
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Min Young Lee. (2013) Protection of Primary Cultured Mouse Hepatocytes from Chemical Hypoxia-induced Injury by Hydrogen Sulfide. Journal of Life Science 23:11, pages 1342-1350.
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Nevena Barudzic, Drenka Turjacanin-Pantelic, Vladimir Zivkovic, Dragica Selakovic, Ivan Srejovic, Jovana Jakovljevic, Dragan M. Djuric & Vladimir Lj. Jakovljevic. (2013) The effects of cyclooxygenase and nitric oxide synthase inhibition on oxidative stress in isolated rat heart. Molecular and Cellular Biochemistry 381:1-2, pages 301-311.
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Naoko Kamo, Bibo Ke, Amir A. Ghaffari, Xiu-da Shen, Ronald W. Busuttil, Genhong Cheng & Jerzy W. Kupiec-Weglinski. (2013) ASC/caspase-1/IL-1β signaling triggers inflammatory responses by promoting HMGB1 induction in liver ischemia/reperfusion injury. Hepatology 58:1, pages 351-362.
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Katrien Vekemans, Diethard Monbaliu, Erika Balligand, Veerle Heedfeld, Ina Jochmans, Jacques Pirenne & Jos van Pelt. (2012) Improving the function of liver grafts exposed to warm ischemia by the leuven drug protocol: Exploring the molecular basis by microarray. Liver Transplantation 18:2, pages 206-218.
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