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Inhalation Toxicology
International Forum for Respiratory Research
Volume 15, 2003 - Issue 7
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Research Article

The Fate of Antioxidant Enzymes in Bronchoalveolar Lavage Fluid Over 7 Days in Mice with Acute Lung Injury

Alfred M. Sciuto Pharmacology Division, Neurotoxicology Branch, U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, USA
,
Matthew B. Cascio Pharmacology Division, Neurotoxicology Branch, U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, USA
,
Theodore S. Moran Pharmacology Division, Neurotoxicology Branch, U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, USA
&
Jeffry S. Forster Pharmacology Division, Neurotoxicology Branch, U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, USA
Pages 675-685 | Published online: 01 Oct 2008

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Stephen T. Hobson, Richard A. Richieri & Missag H. Parseghian. (2021) Phosgene: toxicology, animal models, and medical countermeasures. Toxicology Mechanisms and Methods 31:4, pages 293-307.
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Stephen T. Hobson, Robert P. Casillas, Richard A. Richieri, Robert N. Nishimura, Richard H. Weisbart, Rick Tuttle, Glenn T. Reynolds & Missag H. Parseghian. (2019) Development of an acute, short-term exposure model for phosgene. Toxicology Mechanisms and Methods 29:8, pages 604-615.
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Jennifer L. Plahovinsak, Mark R. Perry, Katherine A. Knostman, Robert Segal & Michael C. Babin. (2015) Characterization of a nose-only inhaled phosgene acute lung injury mouse model . Inhalation Toxicology 27:14, pages 832-840.
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Michael W. Perkins, Zdenka Pierre, Peter Rezk, Jian Song, Seema Marshall, Samuel Oguntayo, Venee Morthole, Alfred M. Sciuto, Bhupendra P. Doctor & Madhusoodana P. Nambiar. (2011) Endotracheal aerosolization of atropine sulfate protects against soman-induced acute respiratory toxicity in guinea pigs. Inhalation Toxicology 23:4, pages 182-195.
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Jürgen Pauluhn. (2011) Acute nose-only inhalation exposure of rats to di- and triphosgene relative to phosgene. Inhalation Toxicology 23:2, pages 65-73.
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Christopher Grainge & Paul Rice. (2010) Management of phosgene-induced acute lung injury. Clinical Toxicology 48:6, pages 497-508.
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Karen E Iles, Weifeng Song, David W Miller, Dale A Dickinson & Sadis Matalon. (2009) Reactive species and pulmonary edema. Expert Review of Respiratory Medicine 3:5, pages 487-496.
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Hong-li Chen, Chun-xu Hai, Xin Liang, Xiao-di Zhang, Riu Liu & Xu-jun Qin. (2009) Correlation Between sPLA2-llA and Phosgene-Induced Rat Acute Lung Injury. Inhalation Toxicology 21:4, pages 374-380.
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Xiao-di Zhang, Chun-xu Hai, Feng-lei Cai, Xin Liang, Rui Liu, Hong-li Chen, Xu-jun Qin & An-ji Feng. (2008) Time Course for Expression of VEGF and Its Receptor and Regulator Levels of Contraction and Relaxation in Increased Vascular Permeability of Lung Induced by Phosgene. Inhalation Toxicology 20:9, pages 805-812.
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J. Pauluhn, A. Carson, D. L. Costa, T. Gordon, U. Kodavanti, J. A. Last, M. A. Matthay, K. E. Pinkerton & A. M. Sciuto. (2007) Workshop Summary: Phosgene-Induced Pulmonary Toxicity Revisited: Appraisal of Early and Late Markers of Pulmonary Injury From Animal Models With Emphasis on Human Significance. Inhalation Toxicology 19:10, pages 789-810.
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Jürgen Pauluhn. (2006) Acute Nose-Only Exposure of Rats to Phosgene. Part II. Concentration × Time Dependence of Changes in Bronchoalveolar Lavage During a Follow-Up Period of 3 Months. Inhalation Toxicology 18:9, pages 595-607.
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Jürgen Pauluhn. (2006) Acute Nose-Only Exposure of Rats to Phosgene. Part I: Concentration × Time Dependence of LC50s, Nonlethal-Threshold Concentrations, and Analysis of Breathing Patterns. Inhalation Toxicology 18:6, pages 423-435.
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Alfred M. Sciuto & Holcombe H. Hurt. (2004) Therapeutic Treatments of Phosgene-Induced Lung Injury. Inhalation Toxicology 16:8, pages 565-580.
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Articles from other publishers (17)

Qianying Lu, Siyu Huang, Xiangyan Meng, Jianfeng Zhang, Sifan Yu, Junfeng Li, Mingyu Shi, Haojun Fan & Yanmei Zhao. (2021) Mechanism of Phosgene-Induced Acute Lung Injury and Treatment Strategy. International Journal of Molecular Sciences 22:20, pages 10933.
Crossref
Alfred M. Sciuto & Urmila P. Kodavanti. 2020. Handbook of Toxicology of Chemical Warfare Agents. Handbook of Toxicology of Chemical Warfare Agents 515 544 .
Wesley W. Holmes, Brian M. Keyser, Danielle C. Paradiso, Radharaman Ray, Devon K. Andres, Betty J. Benton, Cristin C. Rothwell, Heidi M. Hoard-Fruchey, James F. Dillman, Alfred M. Sciuto & Dana R. Anderson. (2016) Conceptual approaches for treatment of phosgene inhalation-induced lung injury. Toxicology Letters 244, pages 8-20.
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. 2002. The MAK-Collection for Occupational Health and Safety. The MAK-Collection for Occupational Health and Safety 1 58 .
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 21 .
George D. Leikauf, Vincent J. Concel, Kiflai Bein, Pengyuan Liu, Annerose Berndt, Timothy M. Martin, Koustav Ganguly, An Soo Jang, Kelly A. Brant, Richard A. DopicoJr.Jr., Swapna Upadhyay, Clinton Cario, Y. P. Peter Di, Louis J. Vuga, Emrah Kostem, Eleazar Eskin, Ming You, Naftali Kaminski, Daniel R. Prows, Daren L. Knoell & James P. Fabisiak. (2013) Functional Genomic Assessment of Phosgene-Induced Acute Lung Injury in Mice. American Journal of Respiratory Cell and Molecular Biology 49:3, pages 368-383.
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Wenli Li, Fangfang Liu, Chen Wang, Hubert Truebel & Juergen Pauluhn. (2013) Novel Insights Into Phosgene-Induced Acute Lung Injury in Rats: Role of Dysregulated Cardiopulmonary Reflexes and Nitric Oxide in Lung Edema Pathogenesis. Toxicological Sciences 131:2, pages 612-628.
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Hong‐li Chen, Hua Bai, Miao‐miao Xi, Riu Liu, Xu‐jun Qin, Xin Liang, Wei Zhang, Xiao‐di Zhang, Wen‐li Li & Chun‐xu Hai. (2011) Ethyl pyruvate protects rats from phosgene‐induced pulmonary edema by inhibiting cyclooxygenase2 and inducible nitric oxide synthase expression. Journal of Applied Toxicology 33:1, pages 71-77.
Crossref
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 19 .
. 2002. The MAK-Collection for Occupational Health and Safety. The MAK-Collection for Occupational Health and Safety 1 318 .
George D. Leikauf & Daniel R. Prows. 2003. Patty's Toxicology. Patty's Toxicology 949 1032 .
Robert L. Maynard & Robert P. Chilcott. 2009. General, Applied and Systems Toxicology. General, Applied and Systems Toxicology.
Peter Kovacic & Ratnasamy Somanathan. 2009. Reviews of Environmental Contamination and Toxicology Vol 201. Reviews of Environmental Contamination and Toxicology Vol 201 41 69 .
Danielle B. Peterson, Tara Sander, Sushma Kaul, Bassam T. Wakim, Brian Halligan, Simon Twigger, Kirkwood A. PritchardJr.Jr., Keith T. Oldham & Jing‐Song Ou. (2008) Comparative proteomic analysis of PAI‐1 and TNF‐alpha‐derived endothelial microparticles. PROTEOMICS 8:12, pages 2430-2446.
Crossref
Jennifer Sekowski & James Dillman Iii. 2007. Chemical Warfare Agents. Chemical Warfare Agents.
William Smith & Harry Salem. 2006. Toxicologic Biomarkers. Toxicologic Biomarkers 259 272 .
Alfred Sciuto. 2005. Inhalation Toxicology, Second Edition. Inhalation Toxicology, Second Edition 457 483 .

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