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Inhalation Toxicology
International Forum for Respiratory Research
Volume 15, 2003 - Issue 12
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Research Article

Lung Hyperpermeability, Clara-Cell Secretory Protein (CC16), and Susceptibility to Ozone of Five Inbred Strains of Mice

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Pages 1209-1230 | Published online: 01 Oct 2008

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William O. Ward, Allen D. Ledbetter, Mette C. Schladweiler & Urmila P. Kodavanti. (2015) Lung transcriptional profiling: insights into the mechanisms of ozone-induced pulmonary injury in Wistar Kyoto rats. Inhalation Toxicology 27:sup1, pages 80-92.
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Urmila P. Kodavanti, Allen D. Ledbetter, Ronald F. Thomas, Judy E. Richards, William O. Ward, Mette C. Schladweiler & Daniel L. Costa. (2015) Variability in ozone-induced pulmonary injury and inflammation in healthy and cardiovascular-compromised rat models. Inhalation Toxicology 27:sup1, pages 39-53.
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Bénédicte Jacquemin, Timo Lanki, Tarja Yli-Tuomi, Marko Vallius, Gerard Hoek, Joachim Heinrich, Kirsi Timonen & Juha Pekkanen. (2009) Source category-specific PM2.5 and urinary levels of Clara cell protein CC16. The ULTRA study. Inhalation Toxicology 21:13, pages 1068-1076.
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Amy P. Wong, Armand Keating & Thomas K. Waddell. (2009) Airway regeneration: the role of the Clara cell secretory protein and the cells that express it. Cytotherapy 11:6, pages 676-687.
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Alfred Bernard. (2008) Critical review of Clara cell protein: sound science?. Biomarkers 13:3, pages 237-243.
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Malinda Wilson, Jonathan H. Widdicombe, Kishorchandra Gohil, Kenneth C. Burtis, Abraham Z. Reznick, Carroll E. Cross & Jason P. Eiserich. (2005) Are Drosophila a Useful Model for Understanding the Toxicity of Inhaled Oxidative Pollutants: A Review. Inhalation Toxicology 17:13, pages 765-774.
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Karine Berthoin, Fabrice Broeckaert, Marjorie Robin, Vincent Haufroid, Claire De Burbure & Alfred Bernard. (2004) Serum pneumoproteins and biomarkers of exposure to urban air pollution: a cross-sectional comparison of policemen and foresters. Biomarkers 9:4-5, pages 341-352.
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Sarah J.D. Nauwelaerts, Nina Van Goethem, Koen De Cremer, Natalia Bustos Sierra, Jordy Vercauteren, Christophe Stroobants, Alfred Bernard, Tim Nawrot, Nancy H.C. Roosens & Sigrid C.J. De Keersmaecker. (2023) Noninvasive integrative approach applied to children in the context of recent air pollution exposure demonstrates association between fractional exhaled nitric oxide (FeNO) and urinary CC16. Environmental Research 216, pages 114441.
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Paul G. Reinhart, Lori White, Jee Young Kim, Lindsay Wichers Stanek, Mary Ross, Barbara Buckley & James A. Murray. 2001. Patty's Industrial Hygiene. Patty's Industrial Hygiene 1 48 .
Gurpreet Kaur Aulakh, Jessica Andrea Brocos Duda, Claudia Marcela Guerrero Soler, Elisabeth Snead & Jaswant Singh. (2020) Characterization of low‐dose ozone‐induced murine acute lung injury. Physiological Reports 8:11.
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Robb W. Glenny, Melissa Krueger, Christian Bauer & Reinhard R. Beichel. (2020) The fractal geometry of bronchial trees differs by strain in mice. Journal of Applied Physiology 128:2, pages 362-367.
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Kaili Ye, Daikun He, Yiru Shao, Ning Xu, Chaoyuan Jin, Lin Zhang & Jie Shen. (2019) Exogenous mesenchymal stem cells affect the function of endogenous lung stem cells (club cells) in phosgene-induced lung injury. Biochemical and Biophysical Research Communications 514:3, pages 586-592.
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Hans Petersen, Shuguang Leng, Steven A. Belinsky, Bruce E. Miller, Ruth Tal-Singer, Caroline A. Owen, Bartolome Celli & Yohannes Tesfaigzi. (2015) Low plasma CC16 levels in smokers are associated with a higher risk for chronic bronchitis. European Respiratory Journal 46:5, pages 1501-1503.
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Túlio Henrique Versiani de Oliveira, Keila Karine Duarte Campos, Nícia Pedreira Soares, Karina Braga Pena, Wanderson Geraldo Lima & Frank Silva Bezerra. (2015) Influence of Sexual Dimorphism on Pulmonary Inflammatory Response in Adult Mice Exposed to Chloroform. International Journal of Toxicology 34:3, pages 250-257.
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Annette C. Rohr. (2013) The health significance of gas- and particle-phase terpene oxidation products: A review. Environment International 60, pages 145-162.
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Vasanthi R. Sunil, Kinal N. Vayas, Christopher B. Massa, Andrew J. Gow, Jeffrey D. Laskin & Debra L. Laskin. (2013) Ozone-Induced Injury and Oxidative Stress in Bronchiolar Epithelium Are Associated with Altered Pulmonary Mechanics. Toxicological Sciences 133:2, pages 309-319.
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Maria Paola Cecchini, Flavia Merigo, Mirko Cristofoletti, Francesco Osculati & Andrea Sbarbati. (2009) Immunohistochemical localization of Clara cell secretory proteins (CC10-CC26) and Annexin-1 protein in rat major salivary glands. Journal of Anatomy 214:5, pages 752-758.
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Radosław Świercz, Tadeusz Hałatek, Wojciech Wąsowicz, Barbara Kur, Zofia Grzelińska & Wanda Majcherek. (2008) Pulmonary Irritation After Inhalation Exposure to Benzalkonium Chloride in Rats. International Journal of Occupational Medicine and Environmental Health 21:2.
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Fulvio Braido, Anna M. Riccio, Laura Guerra, Cinzia Gamalero, Alberto Zolezzi, Francesco Tarantini, Barbara De Giovanni, Chiara Folli, Desideria Descalzi & Giorgio Walter Canonica. (2007) Clara cell 16 protein in COPD sputum: A marker of small airways damage?. Respiratory Medicine 101:10, pages 2119-2124.
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John M. Bishai, Wayne Mitzner, Clarke G. Tankersley & Elizabeth M. Wagner. (2007) PEEP-induced changes in epithelial permeability in inbred mouse strains. Respiratory Physiology & Neurobiology 156:3, pages 340-344.
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John T. Coppens, Laura S. Van Winkle, Kent Pinkerton & Charles G. Plopper. (2007) Distribution of Clara cell secretory protein expression in the tracheobronchial airways of rhesus monkeys. American Journal of Physiology-Lung Cellular and Molecular Physiology 292:5, pages L1155-L1162.
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Ingeborg M. Kooter, Jeroen L. A. Pennings, Paul H. B. Fokkens, Daan L. A. C. Leseman, A. John F. Boere, Miriam E. Gerlofs-Nijland, Flemming R. Cassee, Johanna A. C. Schalk, Tom J. H. Orzechowski, Mirjam M. Schaap, Timo M. Breit, Jan A. M. A. Dormans, Conny T. M. van Oostrom, Annemieke de Vries & Harry van Steeg. (2007) Ozone induces clear cellular and molecular responses in the mouse lung independently of the transcription-coupled repair status. Journal of Applied Physiology 102:3, pages 1185-1192.
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Barbara Magi, Elena Bargagli, Luca Bini & Paola Rottoli. (2006) Proteome analysis of bronchoalveolar lavage in lung diseases. PROTEOMICS 6:23, pages 6354-6369.
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Ragnberth Helleday, Bo Segerstedt, Bertil Forsberg, Ian Mudway, Gunnar Nordberg, Alfred Bernard & Anders Blomberg. (2006) Exploring the Time Dependence of Serum Clara Cell Protein as a Biomarker of Pulmonary Injury in Humans. Chest 130:3, pages 672-675.
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E. Van Miert, X. Dumont & A. Bernard. (2005) CC16 as a marker of lung epithelial hyperpermeability in an acute model of rats exposed to mainstream cigarette smoke. Toxicology Letters 159:2, pages 115-123.
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Alfred Bernard, Sylviane Carbonnelle, Marc Nickmilder & Claire de Burbure. (2005) Non-invasive biomarkers of pulmonary damage and inflammation: Application to children exposed to ozone and trichloramine. Toxicology and Applied Pharmacology 206:2, pages 185-190.
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