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Inhalation Toxicology
International Forum for Respiratory Research
Volume 16, 2004 - Issue 8
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Research Article

Asthmalike Symptoms Following Intratracheal Exposure of Guinea Pigs to Sulfur Mustard Aerosol: Therapeutic Efficacy of Exogenous Lung Surfactant Curosurf and Salbutamol

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Pages 537-548 | Published online: 19 Oct 2008

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Shlomit Dachir, Ishai Rabinovitz, Guy Yaacov, Hila Gutman, Liat Cohen, Vered Horwitz, Maayan Cohen & Tamar Kadar. (2019) Whole body exposure of rats to sulfur mustard vapor. Drug and Chemical Toxicology 42:3, pages 231-242.
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Leila Etemad, Mohammad Moshiri & Mahdi Balali-Mood. (2019) Advances in treatment of acute sulfur mustard poisoning – a critical review. Critical Reviews in Toxicology 49:3, pages 191-214.
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Mohammad Reza Khazdair, Mohammad Hossein Boskabady & Vahideh Ghorani. (2015) Respiratory effects of sulfur mustard exposure, similarities and differences with asthma and COPD. Inhalation Toxicology 27:14, pages 731-744.
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Hassan Ghasemi, Parviz Owlia, Mohammad Reza Jalali-Nadoushan, Shahryar Pourfarzam, Ghasem Azimi, Mohammad-Ebrahim Yarmohammadi, Jalaleddin Shams, Faramarz Fallahi, Sakine Moaiedmohseni, Athar Moin, Roya Yaraee, Mohammad Reza Vaez-Mahdavi, Soghrat Faghihzadeh, Zuhair Mohammad Hassan, Mohammad-Reza Soroush, Mohammad-Mehdi Naghizadeh, Susan K. Ardestani & Tooba Ghazanfari. (2013) A clinicopathological approach to sulfur mustard-induced organ complications: a major review. Cutaneous and Ocular Toxicology 32:4, pages 304-324.
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Feng Ru Tang & Weng Keong Loke. (2012) Sulfur mustard and respiratory diseases. Critical Reviews in Toxicology 42:8, pages 688-702.
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Mohammad Hossein Boskabady, Sediqa Amery, Nassim Vahedi & Mohammad Reza Khakzad. (2011) The effect of vitamin E on tracheal responsiveness and lung inflammation in sulfur mustard exposed guinea pigs. Inhalation Toxicology 23:3, pages 157-165.
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Waylon M. Weber, Dean A. Kracko, Mericka R. Lehman, Clinton M. Irvin, Lee F. Blair, Richard K. White, Janet M. Benson, Gary R. Grotendorst, Yung-Sung Cheng & Jacob D. McDonald. (2010) Inhalation exposure systems for the development of rodent models of sulfur mustard-induced pulmonary injury. Toxicology Mechanisms and Methods 20:1, pages 14-24.
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Magnus M. Che, Michele Conti, Megan Boylan, Alfred M. Sciuto, Richard K. Gordon & Madhusoodana P. Nambiar. (2008) Blood and Bronchoalveolar Lavage Fluid Acetylcholinesterase Levels Following Microinstillation Inhalation Exposure to Sarin in Guinea Pigs. Inhalation Toxicology 20:9, pages 821-828.
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M. P. Nambiar, R. K. Gordon, T. S. Moran, S. M. Richards & A. M. Sciuto. (2007) A Simple Method for Accurate Endotracheal Placement of an Intubation Tube in Guinea Pigs to Assess Lung Injury Following Chemical Exposure. Toxicology Mechanisms and Methods 17:7, pages 385-392.
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Judith Emmler, Maria Iris Hermanns, Dirk Steinritz, Helmut Kreppel, Charles James Kirkpatrick, Wilhelm Bloch, Ladislaus Szinicz & Kai Kehe. (2007) Assessment of Alterations in Barrier Functionality and Induction of Proinflammatory and Cytotoxic Effects After Sulfur Mustard Exposure of an In Vitro Coculture Model of the Human Alveolo-Capillary Barrier. Inhalation Toxicology 19:8, pages 657-665.
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Mostafa Ghanei & Ali Amini Harandi. (2007) Long Term Consequences from Exposure to Sulfur Mustard: A Review. Inhalation Toxicology 19:5, pages 451-456.
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Madhusoodana P. Nambiar, Benjamin S. Wright, Peter E. Rezk, Kelvin B. Smith, Richard K. Gordon, Theodore S. Moran, Shannon M. Richards & Alfred M. Sciuto. (2006) Development of a Microinstillation Model of Inhalation Exposure to Assess Lung Injury Following Exposure to Toxic Chemicals and Nerve Agents in Guinea Pigs. Toxicology Mechanisms and Methods 16:6, pages 295-306.
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Herman P. M. Helden$suffix/text()$suffix/text(), Dory Meent$suffix/text()$suffix/text(), John P. Oostdijk, Marloes J. A. Joosen, Joep H. M. Esch$suffix/text()$suffix/text(), Arnold H. Hammer & Robert V. Diemel. (2004) Protection of Rats Against Perfluoroisobutene (PFIB)-Induced Pulmonary Edema by Curosurf and N-Acetylcysteine. Inhalation Toxicology 16:8, pages 549-564.
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Vahid Pourbarkhordar, Mahdi Balali-Mood, Leila Etemad & Mohammad Moshiri. 2024. Encyclopedia of Toxicology. Encyclopedia of Toxicology 209 223 .
Somaye Sadeghi, Mahtab Tapak, Tooba Ghazanfari & Nariman Mosaffa. (2020) A review of Sulfur Mustard-induced pulmonary immunopathology: An Alveolar Macrophage Approach. Toxicology Letters 333, pages 115-129.
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Rama Malaviya, Jeffrey D. Laskin & Debra L. Laskin. (2020) Long-term Respiratory Effects of Mustard Vesicants. Toxicology Letters 319, pages 168-174.
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Zhu Xiaoji, Meng Xiao, Xu Rui, Chu Haibo, Zhao Chao, Lian Chengjin, Wang Tao, Guo Wenjun & Zhang Shengming. (2014) Mechanism underlying acute lung injury due to sulfur mustard exposure in rats. Toxicology and Industrial Health 32:8, pages 1345-1357.
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Barry Weinberger, Rama Malaviya, Vasanthi R. Sunil, Alessandro Venosa, Diane E. Heck, Jeffrey D. Laskin & Debra L. Laskin. (2016) Mustard vesicant-induced lung injury: Advances in therapy. Toxicology and Applied Pharmacology 305, pages 1-11.
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Mostafa Ghanei & Ali Amini Harandi. 2016. Mustard Lung. Mustard Lung 107 138 .
Mostafa Ghanei & Amin Saburi. 2015. Basic and Clinical Toxicology of Mustard Compounds. Basic and Clinical Toxicology of Mustard Compounds 171 212 .
Ramin Zojaji & Morteza Mazloum Farsi Baf. 2015. Basic and Clinical Toxicology of Mustard Compounds. Basic and Clinical Toxicology of Mustard Compounds 135 170 .
Brian M. Keyser, Devon K. Andres, Wesley W. Holmes, Danielle Paradiso, Ashley Appell, Valerie A. Letukas, Betty Benton, Offie E. Clark, Xiugong Gao, Prabhati Ray, Dana R. Anderson & Radharaman Ray. (2014) Mustard Gas Inhalation Injury. International Journal of Toxicology 33:4, pages 271-281.
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Vasanthi R. Sunil, Kinal Patel-Vayas, Jianliang Shen, Andrew J. Gow, Jeffrey D. Laskin & Debra L. Laskin. (2011) Role of TNFR1 in lung injury and altered lung function induced by the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide. Toxicology and Applied Pharmacology 250:3, pages 245-255.
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Barry Weinberger, Jeffrey D. Laskin, Vasanthi R. Sunil, Patrick J. Sinko, Diane E. Heck & Debra L. Laskin. (2011) Sulfur mustard-induced pulmonary injury: Therapeutic approaches to mitigating toxicity. Pulmonary Pharmacology & Therapeutics 24:1, pages 92-99.
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Vasanthi R. Sunil, Kinal J. Patel, Jianliang Shen, David Reimer, Andrew J. Gow, Jeffrey D. Laskin & Debra L. Laskin. (2011) Functional and inflammatory alterations in the lung following exposure of rats to nitrogen mustard. Toxicology and Applied Pharmacology 250:1, pages 10-18.
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Kamyar Ghabili, Paul S. Agutter, Mostafa Ghanei, Khalil Ansarin & Mohammadali M. Shoja. (2010) Mustard gas toxicity: the acute and chronic pathological effects. Journal of Applied Toxicology 30:7, pages 627-643.
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Nahum Allon, Adina Amir, Eliau Manisterski, Ishay Rabinovitz, Shlomit Dachir & Tamar Kadar. (2009) Inhalation exposure to sulfur mustard in the guinea pig model: Clinical, biochemical and histopathological characterization of respiratory injuries. Toxicology and Applied Pharmacology 241:2, pages 154-162.
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Veit J. Erpenbeck, Norbert Krug & Jens M. Hohlfeld. (2008) Therapeutic use of surfactant components in allergic asthma. Naunyn-Schmiedeberg's Archives of Pharmacology 379:3, pages 217-224.
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Claudia Karacsonyi, Naga Shanmugam & Elliott Kagan. (2009) A clinically relevant in vitro model for evaluating the effects of aerosolized vesicants. Toxicology Letters 185:1, pages 38-44.
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R. Vijayaraghavan, Anshoo Gautam & Manoj Sharma. 2009. Handbook of Toxicology of Chemical Warfare Agents. Handbook of Toxicology of Chemical Warfare Agents 897 918 .
Peter Kovacic & Ratnasamy Somanathan. 2009. Reviews of Environmental Contamination and Toxicology Vol 201. Reviews of Environmental Contamination and Toxicology Vol 201 41 69 .
Madhusoodana P. Nambiar, Richard K. Gordon, Peter E. Rezk, Alexander M. Katos, Nikolai A. Wajda, Theodore S. Moran, Keith E. Steele, Bhupendra P. Doctor & Alfred M. Sciuto. (2007) Medical countermeasure against respiratory toxicity and acute lung injury following inhalation exposure to chemical warfare nerve agent VX. Toxicology and Applied Pharmacology 219:2-3, pages 142-150.
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