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Journal of Dermatological Treatment Volume 32, 2021 - Issue 7
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Hair and pigment

A comparative study between oral tranexamic acid versus oral tranexamic acid and Q-switched Nd-YAG laser in melasma treatment: a clinical and dermoscopic evaluation

Naglaa Agamiaa Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Alexandria, EgyptCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-0200-3390
ORCID Icon,
Zoe Apallab State Hospital for Dermatologic and Venereologic Diseases, Thessalonik, Greece
,
Walaa Salemc Hospital Administration, High Institute of Public Health. Alexandria University, Alexandria, Egypt
&
Wafaa Abdallaha Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Alexandria, Egypt
Pages 819-826 | Received 06 Jul 2019, Accepted 26 Oct 2019, Published online: 07 Jan 2020

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Nicoleta Neagu, Claudio Conforti, Marina Agozzino, Giovanni Francesco Marangi, Silviu Horia Morariu, Giovanni Pellacani, Paolo Persichetti, Domenico Piccolo, Francesco Segreto, Iris Zalaudek & Caterina Dianzani. (2022) Melasma treatment: a systematic review. Journal of Dermatological Treatment 33:4, pages 1816-1837.
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Wenyi Ma, Qian Gao, Jinghua Liu, Xiaojing Zhong, Tongtong Xu, Qinyao Wu, Zilin Cheng, Nana Luo & Pingsheng Hao. (2023) Efficacy and safety of laser‐related therapy for melasma: A systematic review and network meta‐analysis. Journal of Cosmetic Dermatology 22:11, pages 2910-2924.
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Nisal Punchihewa & Michelle Rodrigues. (2023) A comprehensive review of dermoscopy in melasma. Clinical and Experimental Dermatology.
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Chai Nien Foo, Hemaniswarri Dewi Dewadas, Boon Keat Chin, Tean Chun Teoh, Hong Keat Ong & Yang Mooi Lim. (2023) Acceptability, feasibility and preliminary effectiveness of Picopulse for the treatment of melasma among Malaysian women: A pilot quasi‐experimental. JEADV Clinical Practice.
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So Yeon Lee, Hye Ran Kim, Jin Seo Park, Jin Cheol Kim, Chun Wook Park, Hye One Kim & Bo Young Chung. (2023) The Efficacy and Safety of a Low-Fluence 1064 nm Picosecond ND-YAG Laser Compared with Those of a Low-Fluence Photoacoustic Therapy Pulsed (PTP) Mode 1064 nm Q-Switched ND-YAG Laser for Treatment of Melasma: A Prospective Split-Face Study. Dermatologic Therapy 2023, pages 1-10.
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Arika Latashia Adelia, Sri Adila Nurainiwati, Probo Yudha Pratama Putra & Aulia Sita Hapsari. (2023) Efficacy, effectiveness, and safety of combination laser and tranexamic acid treatment for melasma: A meta-analysis. Chinese Journal of Plastic and Reconstructive Surgery.
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Rongxin Ren, Shiwei Bao, Wenjiang Qian & Hongyi Zhao. (2023) Efficacy and Safety of Picosecond Laser in the Treatment of Melasma: A Network Meta-analysis. Dermatologic Surgery 49:5S, pages S49-S55.
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Ying Li, Wei‐Na Shao, Qing‐Qing Fang, Wan‐yi Zhao, Shi‐qin Wang, Li‐Hong Wu, Yan‐Yan Hu, Xiao‐feng Wang, Ya‐Nan Xue, Li Chen & Wei‐Qiang Tan. (2022) A combination treatment of drug‐laser‐photon for melasma: A retrospective study of clinical cases. Journal of Cosmetic Dermatology 22:3, pages 822-830.
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D. Patricia Apt, P. Daniela Calderon & B. Geraldine Kohn. (2023) Enfrentamiento del paciente con melasma: actualizaciones en tratamiento. Revista Médica Clínica Las Condes 34:2, pages 116-121.
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Nomakhosi Mpofana, Buyisile Chibi, Tronel Visser, Michael Paulse, Avenal Jane Finlayson, Shanaz Ghuman, Nceba Gqaleni, Ahmed A. Hussein & Ncoza Cordelia Dlova. (2023) Treatment of Melasma on Darker Skin Types: A Scoping Review. Cosmetics 10:1, pages 25.
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Rashmi Sarkar, Evangeline B. Handog, Anupam Das, Anuva Bansal, Ma. Juliet Macarayo, Vinay Keshavmurthy, Vignesh Narayan, Soumya Jagadeesan, Eugenio Pipo, Grace Monica Ibaviosa, Indrashis Podder & Shivani Bansal. (2023) Topical and Systemic Therapies in Melasma: A Systematic Review. Indian Dermatology Online Journal 14:6, pages 769-781.
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I.V. Seraya & S.V. Murakov. (2023) Hardware treatment methods of melasma. Klinicheskaya dermatologiya i venerologiya 22:5, pages 610.
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Jessica Cervantes, Nicole Patzelt, Sara Al-Janahi, Dae Hyun Kim & Hye Jin Chung. (2023) Efficacy and Safety of Low Fluence Nd:YAG Laser Treatment in Melasma: A Meta-Analysis and Systematic Review. Dermatologic Surgery 49:1, pages 36-41.
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Kamal Alhallak, Adel Abdulhafid, Salem Tomi & Dima OmranKamal Alhallak, Adel Abdulhafid, Salem Tomi & Dima Omran. 2023. The Ultimate Guide for Laser and IPL in the Aesthetic Field. The Ultimate Guide for Laser and IPL in the Aesthetic Field 181 224 .
Kazuhisa Maeda. (2022) Mechanism of Action of Topical Tranexamic Acid in the Treatment of Melasma and Sun-Induced Skin Hyperpigmentation. Cosmetics 9:5, pages 108.
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Zuzanna Piętowska, Danuta Nowicka & Jacek C. Szepietowski. (2022) Understanding Melasma-How Can Pharmacology and Cosmetology Procedures and Prevention Help to Achieve Optimal Treatment Results? A Narrative Review. International Journal of Environmental Research and Public Health 19:19, pages 12084.
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Yeon Seok Lee, Yu Jin Lee, Jung Min Lee, Tae Young Han, June Hyunkyung Lee & Jae Eun Choi. (2022) The Low-Fluence Q-Switched Nd:YAG Laser Treatment for Melasma: A Systematic Review. Medicina 58:7, pages 936.
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Soha Abdalla Hawwam, Mayada Ismail & Yasmina Ahmed El-Attar. (2022) Split-face comparative study between intradermal tranexamic acid injection alone versus intradermal tranexamic acid injection combined with Q-switched Nd:YAG laser in melasma treatment: dermoscopic and clinical evaluation. Lasers in Medical Science 37:4, pages 2193-2201.
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Abdelaal M. Elkamshoushi, Doaa Romisy & Salma S. Omar. (2021) Oral tranexamic acid, hydroquinone 4% and low‐fluence 1064 nm Q‐switched Nd:YAG laser for mixed melasma: Clinical and dermoscopic evaluation. Journal of Cosmetic Dermatology 21:2, pages 657-668.
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Loren Krueger, Autumn Saizan, Jennifer A. Stein & Nada Elbuluk. (2021) Dermoscopy of acquired pigmentary disorders: a comprehensive review. International Journal of Dermatology 61:1, pages 7-19.
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P.B. Lima, J.A.F. Dias, A.C.C. Esposito, L.D.B. Miot & H.A. Miot. (2020) French maritime pine bark extract (pycnogenol) in association with triple combination cream for the treatment of facial melasma in women: a double‐blind, randomized, placebo‐controlled trial. Journal of the European Academy of Dermatology and Venereology 35:2, pages 502-508.
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Yu.I. Vashkevich & V.V. Krumkachou. (2021) Analysis of the use of tranexamic acid for the treatment of melasma. Klinicheskaya dermatologiya i venerologiya 20:1, pages 157.
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Natasha Masub, Julie K. Nguyen, Evan Austin & Jared Jagdeo. (2020) The Vascular Component of Melasma: A Systematic Review of Laboratory, Diagnostic, and Therapeutic Evidence. Dermatologic Surgery 46:12, pages 1642-1650.
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Xiao Meng & Chen-Chen Xu. (2020) Progress and prospect of non-invasive detection techniques in the therapeutic evaluation of melasma. Chinese Medical Journal 133:17, pages 2104-2106.
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Rania Abdel Hay, Faisal Nouredin Mohammed, Khadiga S. Sayed, Nada Adel Abd El Fattah & Sarah Ibrahim. (2020) Dermoscopy as a useful tool for evaluating melasma and assessing the response to 1064‐nm Q‐switched Nd: YAG laser . Dermatologic Therapy 33:4.
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