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Vijay K. Singh, Meera Srivastava & Thomas M Seed. (2023) Protein biomarkers for radiation injury and testing of medical countermeasure efficacy: promises, pitfalls, and future directions. Expert Review of Proteomics 20:10, pages 221-246.
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Vijay K. Singh & Thomas M Seed. (2023) Development of gamma-tocotrienol as a radiation medical countermeasure for the acute radiation syndrome: current status and future perspectives. Expert Opinion on Investigational Drugs 32:1, pages 25-35.
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Rupak Pathak, Sumit K. Shah & Martin Hauer-Jensen. (2019) Therapeutic potential of natural plant products and their metabolites in preventing radiation enteropathy resulting from abdominal or pelvic irradiation. International Journal of Radiation Biology 95:4, pages 493-505.
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Vladimir N. Bykov, Igor S. Drachev, Sergey Yu. Kraev, Mikhail A. Maydin, Ekaterina A. Gubareva, Sergey E. Pigarev, Vladimir N. Anisimov, Irina A. Baldueva, Elena I. Fedoros & Andrey V. Panchenko. (2018) Radioprotective and radiomitigative effects of BP-C2, a novel lignin-derived polyphenolic composition with ammonium molybdate, in two mouse strains exposed to total body irradiation. International Journal of Radiation Biology 94:2, pages 114-123.
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Vijay K Singh, Victoria L Newman, Patricia LP Romaine, Stephen Y Wise & Thomas M Seed. (2014) Radiation countermeasure agents: an update (2011 – 2014). Expert Opinion on Therapeutic Patents 24:11, pages 1229-1255.
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Vijay K. Singh, Elizabeth J. Ducey, Darren S. Brown & Mark H. Whitnall. (2012) A review of radiation countermeasure work ongoing at the Armed Forces Radiobiology Research Institute. International Journal of Radiation Biology 88:4, pages 296-310.
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Francis Dumont, Antoine Le Roux & Pierre Bischoff. (2010) Radiation countermeasure agents: an update. Expert Opinion on Therapeutic Patents 20:1, pages 73-101.
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Stephen A. Shrum, Ujwani Nukala, Shivangi Shrimali, Edith Nathalie Pineda, Kimberly J. Krager, Shraddha Thakkar, Darin E. Jones, Rupak Pathak, Philip J. Breen, Nukhet Aykin-Burns & Cesar M. Compadre. (2023) Tocotrienols Provide Radioprotection to Multiple Organ Systems through Complementary Mechanisms of Antioxidant and Signaling Effects. Antioxidants 12:11, pages 1987.
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Gregory P. Holmes-Hampton, Vidya P. Kumar, Shukla Biswas, Sasha Stone, Neel K. Sharma, Betre Legesse, Justin Vercellino, Chandan Guha, Gary Eichenbaum & Sanchita P. Ghosh. (2023) PEGylated thrombopoietin mimetic, JNJ‑26366821 a novel prophylactic radiation countermeasure for acute radiation injury. Scientific Reports 13:1.
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Vidya P. Kumar, Shukla Biswas, Gregory P. Holmes-Hampton, Torsten Goesch, William Fahl & Sanchita P. Ghosh. (2023) PrC-210 Protects against Radiation-Induced Hematopoietic and Intestinal Injury in Mice and Reduces Oxidative Stress. Antioxidants 12:7, pages 1417.
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Neetha Nanoth Vellichirammal, Sahil Sethi, Nagavardhini Avuthu, Stephen Y. Wise, Alana D. Carpenter, Oluseyi O. Fatanmi, Chittibabu Guda & Vijay K. Singh. (2023) Transcriptome profile changes in the jejunum of nonhuman primates exposed to supralethal dose of total- or partial-body radiation. BMC Genomics 24:1.
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Inés Lledó, Blanca Ibáñez, Ana Melero, Alegría Montoro, Juan F. Merino-Torres, Nadia San Onofre & Jose M. Soriano. (2023) Vitamins and Radioprotective Effect: A Review. Antioxidants 12:3, pages 611.
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Saniya Arfin & Dhruv Kumar. 2023. Nutraceuticals. Nutraceuticals
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Sook Chin Chew & Suk Kuan Teng. 2023. Bioactive Phytochemicals from Vegetable Oil and Oilseed Processing By-products. Bioactive Phytochemicals from Vegetable Oil and Oilseed Processing By-products
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Tarun K. Garg, Sarita Garg, Isabelle R. Miousse, Stephen Y. Wise, Alana D. Carpenter, Oluseyi O. Fatanmi, Frits van Rhee, Vijay K. Singh & Martin Hauer-Jensen. (2022) Gamma-Tocotrienol Modulates Total-Body Irradiation-Induced Hematopoietic Injury in a Nonhuman Primate Model. International Journal of Molecular Sciences 23:24, pages 16170.
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Dharmendra Kumar Soni, Vidya P. Kumar, Shukla Biswas, Gregory P. Holmes-Hampton, Sharmistha Bhattacharyya, Lawrence J. Thomas, Roopa Biswas & Sanchita P. Ghosh. (2022) CDX-301 prevents radiation-induced dysregulation of miRNA expression and biogenesis. Molecular Therapy - Nucleic Acids 30, pages 569-584.
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Karson S. Putt, Yuhong Du, Haian Fu & Zhong-Yin Zhang. (2022) High-throughput screening strategies for space-based radiation countermeasure discovery. Life Sciences in Space Research 35, pages 88-104.
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Vidya P. Kumar, Shukla Biswas, Gregory P. Holmes-Hampton, Michal Sheleg, Sasha Stone, Betre Legesse, Racheli Ofir & Sanchita P. Ghosh. (2022) Pre-Administration of PLX-R18 Cells Protects Mice from Radiation-Induced Hematopoietic Failure and Lethality. Genes 13:10, pages 1756.
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Sarita Garg, Tarun K. Garg, Isabelle R. Miousse, Stephen Y. Wise, Oluseyi O. Fatanmi, Alena V. Savenka, Alexei G. Basnakian, Vijay K. Singh & Martin Hauer-Jensen. (2022) Effects of Gamma-Tocotrienol on Partial-Body Irradiation-Induced Intestinal Injury in a Nonhuman Primate Model. Antioxidants 11:10, pages 1895.
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Neetha Nanoth Vellichirammal, Sahil Sethi, Sanjit Pandey, Jatinder Singh, Stephen Y. Wise, Alana D. Carpenter, Oluseyi O. Fatanmi, Chittibabu Guda & Vijay K. Singh. (2022) Lung transcriptome of nonhuman primates exposed to total- and partial-body irradiation. Molecular Therapy - Nucleic Acids 29, pages 584-598.
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Mohamed. Khattab, Zeinab Sayed, Rawan. Altaf, Noha Yasen, Ahmed Al Aiashy, Hajar Alfeqy, Galal khedr, Shurouk. Atef, Doaa Ezzat & Mohamed Nafady. (2022) The prophylactic roles of dietary antioxidants for medical radiology workers: A mini-review. Natural Resources for Human Health 2:4, pages 391-407.
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Karolina Tremmel-Bede, Marietta Szentmiklóssy, Anna-Maija Lampi, Vieno Piironen, Peter R. Shewry, Gyula Vida, Sándor Tömösközi, Ildikó Karsai, László Láng, Zoltán Bedő & Marianna Rakszegi. (2022) Variation in the Content and Composition of Tocols in a Wheat Population. Foods 11:9, pages 1343.
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Sarita Garg, Tarun K. Garg, Stephen Y. Wise, Oluseyi O. Fatanmi, Isabelle R. Miousse, Alena V. Savenka, Alexei G. Basnakian, Vijay K. Singh & Martin Hauer-Jensen. (2022) Effects of Gamma-Tocotrienol on Intestinal Injury in a GI-Specific Acute Radiation Syndrome Model in Nonhuman Primate. International Journal of Molecular Sciences 23:9, pages 4643.
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Vidya P. Kumar, Gregory P. Holmes-Hampton, Shukla Biswas, Sasha Stone, Neel Kamal Sharma, Bernadette Hritzo, Mary Guilfoyle, Gary Eichenbaum, Chandan Guha & Sanchita P. Ghosh. (2022) Mitigation of total body irradiation-induced mortality and hematopoietic injury of mice by a thrombopoietin mimetic (JNJ-26366821). Scientific Reports 12:1.
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Elliot Rosen, Oluseyi O. Fatanmi, Stephen Y. Wise, V. Ashutosh Rao & Vijay K. Singh. (2022) Gamma-tocotrienol, a radiation countermeasure, reverses proteomic changes in serum following total-body gamma irradiation in mice. Scientific Reports 12:1.
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H. Jervoise N. Andreyev, Jennifer Matthews, Carolyn Adams, Lone Gothard, Claire Lucy, Holly Tovey, Sue Boyle, Selvakumar Anbalagan, Annette Musallam, John Yarnold, David Abraham, Judith Bliss, Bahja Ahmed Abdi, Alexandra Taylor & Martin Hauer-Jensen. (2022) Randomised single centre double-blind placebo controlled phase II trial of Tocovid SupraBio in combination with pentoxifylline in patients suffering long-term gastrointestinal adverse effects of radiotherapy for pelvic cancer: The PPALM study. Radiotherapy and Oncology 168, pages 130-137.
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Veera Ranjani Rajagopalan, Sudha Manickam & Raveendran Muthurajan. (2022) A Comparative Metabolomic Analysis Reveals the Nutritional and Therapeutic Potential of Grains of the Traditional Rice Variety Mappillai Samba. Plants 11:4, pages 543.
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Grazyna Nowak & Judit Megyesi. (2021) γ-Tocotrienol Protects against Mitochondrial Dysfunction, Energy Deficits, Morphological Damage, and Decreases in Renal Functions after Renal Ischemia. International Journal of Molecular Sciences 22:23, pages 12674.
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Ashley S. Nemec-Bakk, Vijayalakshmi Sridharan, Reid D. Landes, Preeti Singh, Maohua Cao, John W. Seawright, Xingui Liu, Guangrong Zheng, Paari Dominic, Rupak Pathak & Marjan Boerma. (2021) Mitigation of late cardiovascular effects of oxygen ion radiation by γ-tocotrienol in a mouse model. Life Sciences in Space Research 31, pages 43-50.
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Ahmad Farouk Musa. 2021. Vitamin E in Health and Disease - Interactions, Diseases and Health Aspects. Vitamin E in Health and Disease - Interactions, Diseases and Health Aspects.
Balazs J. Bene, William F. Blakely, David M. Burmeister, Lynnette Cary, Suyog J. Chhetri, Catherine M. Davis, Sanchita P. Ghosh, Gregory P. Holmes-Hampton, Sergey Iordanskiy, John F. Kalinich, Juliann G. Kiang, Vidya P. Kumar, R. Joel Lowy, Alexandra Miller, Mohammad Naeem, David A. Schauer, Lien Senchak, Vijay K. Singh, Aure J. Stewart, Elih M. Velazquez & Mang Xiao. (2021) Celebrating 60 Years of Accomplishments of the Armed Forces Radiobiology Research Institute1. Radiation Research 196:2.
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Kimberly J. Jurgensen, William K. J. Skinner, Bryan Oronsky, Nacer D. Abrouk, Andrew E. Graff, Reid D. Landes, William E. Culp, Thomas A. SummersJrJr & Lynnette H. Cary. (2021) RRx-001 Radioprotection: Enhancement of Survival and Hematopoietic Recovery in Gamma-Irradiated Mice. Frontiers in Pharmacology 12.
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Sang-gyu Lee, Teja Muralidhar Kalidindi, Hanzhi Lou, Kishore Gangangari, Blesida Punzalan, Ariana Bitton, Casey J. Lee, Hebert A. Vargas, Soobin Park, Lisa Bodei, Michael G. Kharas, Vijay K. Singh, Naga Vara Kishore Pillarsetty & Steven M. Larson. (2021) γ-Tocotrienol–Loaded Liposomes for Radioprotection from Hematopoietic Side Effects Caused by Radiotherapeutic Drugs. Journal of Nuclear Medicine 62:4, pages 584-590.
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Sook Chin Chew & Suk Kuan Teng. 2020. Bioactive Phytochemicals from Vegetable Oil and Oilseed Processing By-products. Bioactive Phytochemicals from Vegetable Oil and Oilseed Processing By-products
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Vidya P. Kumar, Sasha Stone, Shukla Biswas, Neel Sharma & Sanchita P. Ghosh. (2020) Gamma Tocotrienol Protects Mice From Targeted Thoracic Radiation Injury. Frontiers in Pharmacology 11.
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Elena Obrador, Rosario Salvador, Juan I. Villaescusa, José M. Soriano, José M. Estrela & Alegría Montoro. (2020) Radioprotection and Radiomitigation: From the Bench to Clinical Practice. Biomedicines 8:11, pages 461.
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Bin Shen, Pingping Zhou, Xue Jiao, Zhen Yao, Lidan Ye & Hongwei Yu. (2020) Fermentative production of Vitamin E tocotrienols in Saccharomyces cerevisiae under cold-shock-triggered temperature control. Nature Communications 11:1.
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Elliot Rosen, Oluseyi O. Fatanmi, Stephen Y. Wise, V. Ashutosh Rao & Vijay K. Singh. (2020) Tocol Prophylaxis for Total-body Irradiation: A Proteomic Analysis in Murine Model. Health Physics 119:1, pages 12-20.
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Xingui Liu, Zhengya Gao, Qiang Fu, Lin Song, Peiyi Zhang, Xuan Zhang, Howard Hendrickson, Peter A. Crooks, Daohong Zhou & Guangrong Zheng. (2020) Deuteration of the farnesyl terminal methyl groups of δ-tocotrienol and its effects on the metabolic stability and ability of inducing G-CSF production. Bioorganic & Medicinal Chemistry 28:11, pages 115498.
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Nabarun Chakraborty, Aarti Gautam, Gregory P. Holmes-Hampton, Vidya P. Kumar, Shukla Biswas, Raina Kumar, Dana Hamad, George Dimitrov, Ayodele O. Olabisi, Rasha Hammamieh & Sanchita P. Ghosh. (2020) microRNA and Metabolite Signatures Linked to Early Consequences of Lethal Radiation. Scientific Reports 10:1.
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Xingui Liu, Saikat Poddar, Lin Song, Howard Hendrickson, Xuan Zhang, Yaxia Yuan, Daohong Zhou & Guangrong Zheng. (2020) Synthesis and Liver Microsomal Metabolic Stability Studies of a Fluorine‐Substituted δ‐Tocotrienol Derivative. ChemMedChem 15:6, pages 506-516.
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Merriline Satyamitra, Lynnette Cary, Dylan Dunn, Gregory P. Holmes-Hampton, Lawrence J. Thomas & Sanchita P. Ghosh. (2020) CDX-301: a novel medical countermeasure for hematopoietic acute radiation syndrome in mice. Scientific Reports 10:1.
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Xiaona Zhang, Pingbo Li, Peng Yun, Lingqiang Wang, Guanjun Gao, Qinglu Zhang, Lijun Luo, Chunyu Zhang & Yuqing He. (2019)
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Rahul Checker, Debojyoti Pal, Raghavendra S. Patwardhan, Bhakti Basu, Deepak Sharma & Santosh K. Sandur. (2019) Modulation of Caspase-3 activity using a redox active vitamin K3 analogue, plumbagin, as a novel strategy for radioprotection. Free Radical Biology and Medicine 143, pages 560-572.
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Rupak Pathak, Vidya Prasanna Kumar, Martin Hauer-Jensen & Sanchita Purohit Ghosh. (2019) Enhanced Survival in Mice Exposed to Ionizing Radiation by Combination of Gamma-Tocotrienol and Simvastatin. Military Medicine 184:Supplement_1, pages 644-651.
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Nukhet Aykin-Burns, Rupak Pathak, Marjan Boerma, Thomas Kim & Martin Hauer-Jensen. (2019) Utilization of Vitamin E Analogs to Protect Normal Tissues While Enhancing Antitumor Effects. Seminars in Radiation Oncology 29:1, pages 55-61.
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Vidya P. KumarShukla BiswasNeel K. SharmaSasha StoneChristine M. FamGeorge N. CoxSanchita P. Ghosh. (2018) PEGylated IL‐11 (BBT‐059): A Novel Radiation Countermeasure for Hematopoietic Acute Radiation Syndrome. Health Physics 115:1, pages 65-76.
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Merriline Satyamitra, Vidya P. Kumar, Shukla Biswas, Lynnette Cary, Leonora Dickson, Srinivasan Venkataraman & Sanchita P. Ghosh. (2017) Impact of Abbreviated Filgrastim Schedule on Survival and Hematopoietic Recovery after Irradiation in Four Mouse Strains with Different Radiosensitivity. Radiation Research 187:6, pages 659.
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Zhong-Tang Li, Li-Mei Wang, Li-Rong Yi, Chao Jia, Fan Bai, Ren-Jun Peng, Zu-Yin Yu, Guo-Lin Xiong, Shuang Xing, Ya-Jun Shan, Ri-Fang Yang, Jun-Xing Dong & Yu-Wen Cong. (2017) Succinate ester derivative of δ-tocopherol enhances the protective effects against 60Co γ-ray-induced hematopoietic injury through granulocyte colony-stimulating factor induction in mice. Scientific Reports 7:1.
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Grace Ledet, Shukla Biswas, Vidya Kumar, Richard Graves, Demaurian Mitchner, Taylor Parker, Levon Bostanian, Sanchita Ghosh & Tarun Mandal. (2016) Development of Orally Administered γ-Tocotrienol (GT3) Nanoemulsion for Radioprotection. International Journal of Molecular Sciences 18:1, pages 28.
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Vijay K. Singh, Stephen Y. Wise, Jessica R. Scott, Patricia L.P. Romaine, Victoria L. Newman & Oluseyi O. Fatanmi. (2014) Radioprotective efficacy of delta-tocotrienol, a vitamin E isoform, is mediated through granulocyte colony-stimulating factor. Life Sciences 98:2, pages 113-122.
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Cesar M. Compadre, Awantika Singh, Shraddha Thakkar, Guangrong Zheng, Philip J. Breen, Sanchita Ghosh, Mahmoud Kiaei, Marjan Boerma, Kottayil I. Varughese & Martin Hauer-Jensen. (2014) Molecular Dynamics Guided Design of Tocoflexol: A New Radioprotectant Tocotrienol with Enhanced Bioavailability. Drug Development Research 75:1, pages 10-22.
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Shubhankar Suman, Kamal Datta, Kushal Chakraborty, Shilpa S. Kulkarni, Kathryn Doiron, Albert J. FornaceJr.Jr., K. Sree Kumar, Martin Hauer-Jensen & Sanchita P. Ghosh. (2013) Gamma tocotrienol, a potent radioprotector, preferentially upregulates expression of anti-apoptotic genes to promote intestinal cell survival. Food and Chemical Toxicology 60, pages 488-496.
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Kentaro Matsuzuka, Eiichi Kimura, Kiyotaka Nakagawa, Kazumasa Murata, Toshiyuki Kimura & Teruo Miyazawa. (2013) Investigation of tocotrienol biosynthesis in rice (Oryza sativa L.). Food Chemistry 140:1-2, pages 91-98.
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Shilpa Kulkarni, Kushal Chakraborty, K. Sree Kumar, Tzu-Cheg Kao, Martin Hauer-Jensen & Sanchita P. Ghosh. (2013) Synergistic Radioprotection by Gamma-Tocotrienol and Pentoxifylline: Role of cAMP Signaling. ISRN Radiology 2013, pages 1-11.
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Shilpa Kulkarni, Pankaj K. Singh, Sanchita P. Ghosh, Ana Posarac & Vijay K. Singh. (2013) Granulocyte colony-stimulating factor antibody abrogates radioprotective efficacy of gamma-tocotrienol, a promising radiation countermeasure. Cytokine 62:2, pages 278-285.
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Sugata Ray, Shilpa S. Kulkarni, Kushal Chakraborty, Roli Pessu, Martin Hauer-Jensen, K. Sree Kumar & Sanchita P. Ghosh. (2013) Mobilization of progenitor cells into peripheral blood by gamma-tocotrienol: A promising radiation countermeasure. International Immunopharmacology 15:3, pages 557-564.
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Pankaj K Singh, Stephen Y Wise, Elizabeth J Ducey, Oluseyi O Fatanmi, Thomas B Elliott & Vijay K Singh. (2012) α-Tocopherol Succinate Protects Mice against Radiation-Induced Gastrointestinal Injury. Radiation Research 177:2, pages 133-145.
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Chandan Wilankar, Deepak Sharma, Rahul Checker, Nazir M. Khan, Raghavendra Patwardhan, Anand Patil, Santosh Kumar Sandur & T.P.A. Devasagayam. (2011) Role of immunoregulatory transcription factors in differential immunomodulatory effects of tocotrienols. Free Radical Biology and Medicine 51:1, pages 129-143.
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Merriline Satyamitra, Eric Lombardini, John Graves, Conor Mullaney, Patrick Ney, Jeffrey Hunter, Krista Johnson, Paul Tamburini, Yi Wang, Jeremy P. Springhorn & Venkataraman Srinivasan. (2011) A TPO Receptor Agonist, ALXN4100TPO, Mitigates Radiation-Induced Lethality and Stimulates Hematopoiesis in CD2F1 Mice. Radiation Research 175:6, pages 746.
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Maaike Berbee, Qiang Fu, Marjan Boerma, Rupak Pathak, Daohong Zhou, K. Sree Kumar & Martin Hauer-Jensen. (2011) Reduction of Radiation-Induced Vascular Nitrosative Stress by the Vitamin E Analog γ-Tocotrienol: Evidence of a Role for Tetrahydrobiopterin. International Journal of Radiation Oncology*Biology*Physics 79:3, pages 884-891.
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Aaron P Brown, Eun Joo Chung, Mary Ellen Urick, William P ShieldIIIIII, Anastasia L Sowers, Angela Thetford, Uma T Shankavaram, James B Mitchell & Deborah E Citrin. (2010) Evaluation of the fullerene compound DF-1 as a radiation protector. Radiation Oncology 5:1.
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Vijay K. Singh, Darren S. Brown & Tzu-Cheg Kao. (2009) Tocopherol succinate: A promising radiation countermeasure. International Immunopharmacology 9:12, pages 1423-1430.
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