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Original Article

Effect of Hyperthermia at 42 and 45°C on Repair of Radiation-induced DNA Strand Breaks in CHO Cells

Pages 603-614 | Received 09 Jul 1981, Accepted 25 Jan 1982, Published online: 03 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (26)

J. R. Dynlacht, M. Xu, R. K. Pandita, E. A. Wetzel & J. L. Roti Roti. (2004) Effects of heat shock on the Mre11/Rad50/Nbs1 complex in irradiated or unirradiated cells. International Journal of Hyperthermia 20:2, pages 144-156.
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E. P. Armour & G. P. Raaphorst. (2004) Long duration mild temperature hyperthermia and brachytherapy. International Journal of Hyperthermia 20:2, pages 175-189.
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J. DAHM-DAPHI, I. BRAMMER and E. DIKOMEY. (1997) Heat effects on the repair of DNA double-strand breaks in CHO cells. International Journal of Radiation Biology 72:2, pages 171-179.
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G. P. Raaphorst, D. P. Yang, A. Bussey & C. E. Ng. (1995) Cell killing, DNA polymerase inactivation and radiosensitization to low dose rate irradiation by mild hyperthermia in four human cell lines. International Journal of Hyperthermia 11:6, pages 841-854.
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E. Dikomey & H. Jung. (1995) Correlation between Thermal Radiosensitization and Slowly Rejoined DNA Strand Breaks in CHO Cells. International Journal of Radiation Biology 68:3, pages 227-233.
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R.L. Warters. (1993) Persistence of Radiation-induced Double-strand Breaks in the DNA of Heated CHO Cells. International Journal of Radiation Biology 64:6, pages 669-676.
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E. Dikomey & H. Jung. (1993) Correlation between Thermal Radiosensitization and Heat-induced Loss of DNA Polymerase β Activity in CHO Cells. International Journal of Radiation Biology 63:2, pages 215-221.
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E. Dikomey & J. Franzke. (1992) Effect of Heat on Induction and Repair of DNA Strand Breaks in X-irradiated CHO Cells. International Journal of Radiation Biology 61:2, pages 221-233.
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Raymond L. Warters & JoAnn Axtell. (1992) Repair of DNA Strand Breaks at Hyperthermic Temperatures in Chinese Hamster Ovary Cells. International Journal of Radiation Biology 61:1, pages 43-48.
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Jacob C. Lindegaard, Cai Grau & Jens Overgaard. (1991) Effect of Step-down Heating on the Interaction between Heat and Radiation in a C3H Mammary Carcinoma in Vivo. International Journal of Radiation Biology 60:4, pages 707-721.
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Robin L. Anderson, Esther Shiu, George A. Fisher & George M. Hahn. (1988) DNA Damage Does Not Appear to be a Trigger for Thermotolerance in Mammalian Cells. International Journal of Radiation Biology 54:2, pages 285-298.
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Raymond L. Warters, Lucy M. Brizgys & Bradley W. Lyons. (1987) Alterations in the Nuclear Matrix Protein Mass Correlate with Heat-induced Inhibition of DNA Single-strand-break Repair. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 52:2, pages 299-313.
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R.L. Warters, B.W. Lyons & J. Axtell-Bartlett. (1987) Inhibition of Repair of Radiation-induced DNA Damage by Thermal Shock in Chinese Hamster Ovary Cells. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 51:3, pages 505-517.
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Therese M. Coquerelle, Karl F. Weibezahn & Christine Lücke-Huhle. (1987) Rejoining of Double Strand Breaks in Normal Human and Ataxia-telangiectasia Fibroblasts after Exposure to 60Co γ-rays, 241Am α-particles or Bleomycin. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 51:2, pages 209-218.
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Ekkehard Dikomey & Jochen Franzke. (1986) Three Classes of DNA Strand Breaks Induced by X-irradiation and Internal β-rays. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 50:5, pages 893-908.
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H.H. Kampinga, J.B.M. Jorritsma, P. Burgman & A.W.T. Konings. (1986) Differences in Heat-induced Cell Killing as Determined in Three Mammalian Cell Lines Do Not Correspond with the Extent of Heat Radiosensitization. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 50:4, pages 675-684.
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J. B. M. Jorritsma, H. H. Kampinga, A. H. J. Scaf & A. W. T. Konings. (1985) Strand break repair, DNA polymerase activity and heat radiosensitization in thermotolerant cells. International Journal of Hyperthermia 1:2, pages 131-145.
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R.P. Virsik-Peuckert & D. Harder. (1985) Temperature and the Formation of Radiation-induced Chromosome Aberrations. II. The Temperature Dependence of Lesion Repair and Lesion Interaction. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 49:4, pages 673-681.
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C.Z. Chen & D.E. Watt. (1985) Biophysical Mechanism of Radiation Damage to Mammalian Cells by X- and γ-rays. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 49:1, pages 131-142.
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H.H. Kampinga, J.B.M. Jorritsma & A.W.T. Konings. (1985) Heat-induced Alterations in DNA Polymerase Activity of HeLa Cells and of Isolated Nuclei. Relation to Cell Survival. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 47:1, pages 29-40.
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Maurizio Tamba, Giustina Simone & Milton B. Yatvin. (1984) Effect of Hyperthermia and γ-radiation on Escherichia Coli K1060 d-lactate Dehydrogenase. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 46:6, pages 771-778.
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M.V.M. Lafleur, E.J. Pluijmackers-westmijze & H. Loman. (1983) Heat-sensitive Radiation Damage in Single-stranded DNA Irradiated in a Bacterial Extract. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 44:5, pages 483-488.
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Sabine Graubmann & Ekkehard Dikomey. (1983) Induction and Repair of DNA Strand Breaks in CHO-cells Irradiated in Various Phases of the Cycle. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 43:5, pages 475-483.
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G.P. Raaphorst. (1992) Recovery of sublethal radiation damage and its inhibition by hyperthermia in normal and transformed mouse cells. International Journal of Radiation Oncology*Biology*Physics 22:5, pages 1035-1041.
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H P Leenhouts & K H Chadwick. (1990) The influence of dose rate on the dose-effect relationship. Journal of Radiological Protection 10:2, pages 95-102.
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Raymond L. Warters & Lucy M. Brizgys. (2005) Apurinic site induction in the DNA of cells heated at hyperthermic temperatures. Journal of Cellular Physiology 133:1, pages 144-150.
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K. H. Chadwick & H. P. Leenhouts. 1986. Radiation Carcinogenesis and DNA Alterations. Radiation Carcinogenesis and DNA Alterations 277 291 .
Raymond L. Warters, Lucy M. Brizgys & Joann Axtell‐Bartlett. (2005) DNA damage production in CHO cells at elevated temperatures. Journal of Cellular Physiology 124:3, pages 481-486.
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Fred W. Hetzel & Joseph A. Dunn. (1984) Hyperthermia and radiation in cancer therapy: A review. Radiation Physics and Chemistry (1977) 24:3-4, pages 337-345.
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