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Original Article

DNA Double-strand Breaks Generated by the Repair of X-ray Damage in Chinese Hamster Cells

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Pages 671-676 | Received 29 Oct 1981, Accepted 02 Feb 1982, Published online: 03 Jul 2009

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Read on this site (12)

M. Belli, F. Cera, R. Cherubini, F. Ianzini, G. Moschini, O. Sapora, G. Simone, M.A. Tabocchini & P. Tiveron. (1994) DNA Double-strand Breaks Induced by Low Energy Protons in V79 Cells. International Journal of Radiation Biology 65:5, pages 529-536.
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M.D. Story, K.C. Garrett, P.J. Tofilon & R.E. Meyn. (1993) Influence of Irradiation Conditions on the Measurement of DNA Double-strand Breaks by Pulsed-field Gel Electrophoresis. International Journal of Radiation Biology 63:3, pages 297-304.
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G. Iliakis, R. Mehta & M. Jackson. (1992) Level of DNA Double-strand Break Rejoining in Chinese Hamster xrs-5 Cells is Dose-dependent: Implications for the Mechanism of Radiosensitivity. International Journal of Radiation Biology 61:3, pages 315-321.
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Therese M. Coquerelle, Karl F. Weibezahn & Christine Lücke-Huhle. (1987) Rejoining of Double Strand Breaks in Normal Human and Ataxia-telangiectasia Fibroblasts after Exposure to 60Co γ-rays, 241Am α-particles or Bleomycin. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 51:2, pages 209-218.
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Ian R. Radford. (1985) Effect of Radiomodifying Agents on the Ratios of X-ray-induced Lesions in Cellular DNA: Use in Lethal Lesion Determination. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 49:4, pages 621-637.
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Ian R. Radford & George S. Hodgson. (1985) 125I-induced DNA Double Strand Breaks: Use in Calibration of the Neutral Filter Elution Technique and Comparison with X-ray Induced Breaks. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 48:4, pages 555-566.
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P.E. Bryant. (1985) Enzymatic Restriction of Mammalian Cell DNA: Evidence for Double-strand Breaks as Potentially Lethal Lesions. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 48:1, pages 55-60.
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P.E. Bryant. (1984) Enzymatic Restriction of Mammalian Cell DNA Using Pvu II and Bam H1: Evidence for the Double-strand Break Origin of Chromosomal Aberrations. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 46:1, pages 57-65.
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P.E. Bryant. (1983) 9-β-D-Arabinofuranosyladenine Increases the Frequency of X-ray Induced Chromosome Abnormalities in Mammalian Cells. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 43:4, pages 459-464.
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Articles from other publishers (39)

Yasumasa Saisho & Atsushi Ito. (2012) Mathematical models of the generation of radiation-induced DNA double-strand breaks. Journal of Mathematical Biology 67:3, pages 717-736.
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. 2013. DNA Repair and Cancer. DNA Repair and Cancer 19 25 .
Karin Magnander & Kecke Elmroth. (2012) Biological consequences of formation and repair of complex DNA damage. Cancer Letters 327:1-2, pages 90-96.
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Jorge Serment-Guerrero, Matilde Breña-Valle, Magdalena Aguilar-Moreno & Miguel Balcázar. (2012) Evidence of DNA double strand breaks formation in Escherichia coli bacteria exposed to alpha particles of different LET assessed by the SOS response. Applied Radiation and Isotopes 71, pages 66-70.
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Evelyne Sage & Lynn Harrison. (2011) Clustered DNA lesion repair in eukaryotes: Relevance to mutagenesis and cell survival. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 711:1-2, pages 123-133.
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Akinari Yokoya, Kentaro Fujii, Naoya Shikazono & Masatoshi Ukai. 2010. Charged Particle and Photon Interactions with Matter. Charged Particle and Photon Interactions with Matter 543 574 .
Steven A. Roberts, Natasha Strande, Martin D. Burkhalter, Christina Strom, Jody M. Havener, Paul Hasty & Dale A. Ramsden. (2010) Ku is a 5′-dRP/AP lyase that excises nucleotide damage near broken ends. Nature 464:7292, pages 1214-1217.
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Naoya SHIKAZONO, Miho NOGUCHI, Kentaro FUJII, Ayumi URUSHIBARA & Akinari YOKOYA. (2009) The Yield, Processing, and Biological Consequences of Clustered DNA Damage Induced by Ionizing Radiation. Journal of Radiation Research 50:1, pages 27-36.
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B. Paap, D. M. Wilson & B. M. Sutherland. (2008) Human abasic endonuclease action on multilesion abasic clusters: implications for radiation-induced biological damage. Nucleic Acids Research 36:8, pages 2717-2727.
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Megumi HADA & Alexandros G. GEORGAKILAS. (2008) Formation of Clustered DNA Damage after High-LET Irradiation: A Review. Journal of Radiation Research 49:3, pages 203-210.
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Andreyan N. Osipov. 2007. Multiple Stressors: A Challenge for the Future. Multiple Stressors: A Challenge for the Future 429 438 .
Ning Yang, M. Ahmad Chaudhry & Susan S. Wallace. (2006) Base excision repair by hNTH1 and hOGG1: A two edged sword in the processing of DNA damage in γ-irradiated human cells. DNA Repair 5:1, pages 43-51.
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Sei C. Sak, Patricia Harnden, Colin F. Johnston, Alan B. Paul & Anne E. Kiltie. (2005) APE1 and XRCC1 Protein Expression Levels Predict Cancer-Specific Survival Following Radical Radiotherapy in Bladder Cancer. Clinical Cancer Research 11:17, pages 6205-6211.
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V. A. Semenenko & R. D. Stewart. (2005) Monte Carlo Simulation of Base and Nucleotide Excision Repair of Clustered DNA Damage Sites. II. Comparisons of Model Predictions to Measured Data. Radiation Research 164:2, pages 194-201.
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Ning Yang, Heather Galick & Susan S. Wallace. (2004) Attempted base excision repair of ionizing radiation damage in human lymphoblastoid cells produces lethal and mutagenic double strand breaks. DNA Repair 3:10, pages 1323-1334.
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Paula V Bennett, Nela S Cintron, Laurent Gros, Jacques Laval & Betsy M Sutherland. (2004) Are endogenous clustered dna damages induced in human cells?. Free Radical Biology and Medicine 37:4, pages 488-499.
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John M. Akudugu, Jacobus P. Slabbert, Wynand P. Roos & Lothar Böhm. (2003) Micronucleus Response of Human Glioblastoma and Neuroblastoma Cells Toward Low-LET Photon and High-LET p(66)/Be Neutron Irradiation. American Journal of Clinical Oncology 26:3, pages e1-e6.
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Laurent Gros, Murat K Saparbaev & Jacques Laval. (2002) Enzymology of the repair of free radicals-induced DNA damage. Oncogene 21:58, pages 8905-8925.
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Lynn Harrison & Svitlana Malyarchuk. (2002) Can DNA repair cause enhanced cell killing following treatment with ionizing radiation?. Pathophysiology 8:3, pages 149-159.
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BETSY M. SUTHERLAND, PAULA V. BENNETT, NELA CINTRON-TORRES, MEGUMI HADA, JOHN TRUNK, DENISE MONTELEONE, JOHN C. SUTHERLAND, JACQUES LAVAL, MARISHA STANISLAUS & ALAN GEWIRTZ. (2002) Clustered DNA Damages Induced in Human Hematopoietic Cells by Low Doses of Ionizing Radiation. Journal of Radiation Research 43:S, pages S149-S152.
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M. Weinfeld, A. Rasouli-Nia, M. A. Chaudhry & R. A. Britten. (2001) Response of Base Excision Repair Enzymes to Complex DNA Lesions. Radiation Research 156:5, pages 584-589.
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Stéphane Vispé & Masahiko S. Satoh. (2000) DNA Repair Patch-mediated Double Strand DNA Break Formation in Human Cells. Journal of Biological Chemistry 275:35, pages 27386-27392.
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Iwona Gr??dzka, Janusz Skierski & Irena Szumiel. (1998) DNA repair, cell cycle progression and cell death following camptothecin treatment in two murine lymphoma L5178Y sublines. Cell Biochemistry and Function 16:4, pages 239-252.
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M. Ahmad Chaudhry & Michael Weinfeld. (1997) Reactivity of Human Apurinic/Apyrimidinic Endonuclease andEscherichia coli Exonuclease III with Bistranded Abasic Sites in DNA. Journal of Biological Chemistry 272:25, pages 15650-15655.
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Christopher S. Lange, Arthur Cole & Joseph Y. Ostashevsky. 1993. Advances in Radiation Biology - DNA and Chromatin Damage Caused by Radiation. Advances in Radiation Biology - DNA and Chromatin Damage Caused by Radiation 261 421 .
George Lliakis. (2005) The role of DNA double strand breaks in lonizing radiation‐induced killing of eukaryotic cells. BioEssays 13:12, pages 641-648.
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Kunio Shinohara & Atsushi Ito. (2011) Radiation damage in soft X‐ray microscopy of live mammalian cells. Journal of Microscopy 161:3, pages 463-472.
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K. Kishi. (1987) Effects of repair inhibition in the G1 phase of clastogen-treated human lymphocytes on the frequencies of chromosome-type and chromatid-type aberrations and sister-chromatid exchanges. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 176:1, pages 105-116.
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Y. Ejima & M. Sasaki. (1986) Enhanced expression of X-ray- and UV-induced chromosome aberrations by cytosine arabinoside in ataxia telangiectasia cells. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 159:1-2, pages 117-123.
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O. Sapora, A. Maggi & M. Quintiliani. 1986. Radiation Carcinogenesis and DNA Alterations. Radiation Carcinogenesis and DNA Alterations 331 337 .
Dietrich Schulte Frohlinde. 1986. Mechanisms of DNA Damage and Repair. Mechanisms of DNA Damage and Repair 19 27 .
Peter E. Bryant. 1986. Mechanisms of DNA Damage and Repair. Mechanisms of DNA Damage and Repair 171 180 .
B. Ogorek & P.E. Bryant. (1985) Repair of DNA single-strand breaks in X-irradiated yeast. Mutation Research/DNA Repair Reports 146:1, pages 55-61.
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J. Patrick O'Neill & Kimberly B. Flint. (1985) X-ray induction of 6-thioguanine-resistant mutants in division arrested, G0/G1 phase Chinese hamster ovary cells. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 150:1-2, pages 443-450.
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L. Fabry & C. Coton. (1985) Study on the repair of the radioinduced lesions involved in the formation of chromosomal aberrations in G0 human lymphocytes after exposure to γ-rays and fast neutrons. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 149:3, pages 475-483.
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DIETRICH SCHULTE-FROHLINDE & CLEMENS VON SONNTAG. 1985. Oxidative Stress. Oxidative Stress 11 40 .
George Iliakis. (1984) The influence of conditions affecting repair and fixation of potentially lethal damage on the induction of 6-thioguanine resistance after exposure of mammalian cells to X-rays. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 126:2, pages 215-225.
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Peter E. Bryant, Regina Warring & Gunnar Ahnström. (1984) DNA repair kinetics after low doses of X-rays. Mutation Research/DNA Repair Reports 131:1, pages 19-26.
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R. Julian Preston. 1984. Individual Susceptibility to Genotoxic Agents in the Human Population. Individual Susceptibility to Genotoxic Agents in the Human Population 201 210 .

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