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Original Article

Effects of Hyperthermia on the Repair of X-ray-induced DNA Double Strand Breaks in Mouse L Cells

Pages 551-557 | Received 17 Jun 1982, Accepted 30 Dec 1982, Published online: 03 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (24)

Stefan M. Routt, Ju Zhu, Jeffrey M Zaleski & Joseph R Dynlacht. (2011) Potentiation of metalloenediyne cytotoxicity by hyperthermia. International Journal of Hyperthermia 27:5, pages 435-444.
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B. Nevaldine, J. A. Longo & P. J. Hahn. (1994) Hyperthermia inhibits the repair of DNA double-strand breaks induced by ionizing radiation as determined by pulsed-field gel electrophoresis. International Journal of Hyperthermia 10:3, pages 381-388.
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V. V. Deorukhakar, K. B. Anjaria & B. S. Rao. (1993) Modification of radiation-induced damage by hyperthermia—role of repair processes. International Journal of Hyperthermia 9:6, pages 803-810.
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M. Flentje, B. Asadpour, D. Latz & K.J. Weber. (1993) Sensitivity of Neutral Filter Elution but Not PFGE Can Be Modified by Non-dsb Chromatin Damage. International Journal of Radiation Biology 63:6, pages 715-724.
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R.L. Warters. (1993) Persistence of Radiation-induced Double-strand Breaks in the DNA of Heated CHO Cells. International Journal of Radiation Biology 64:6, pages 669-676.
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E. Dikomey & J. Franzke. (1992) Effect of Heat on Induction and Repair of DNA Strand Breaks in X-irradiated CHO Cells. International Journal of Radiation Biology 61:2, pages 221-233.
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Raymond L. Warters & JoAnn Axtell. (1992) Repair of DNA Strand Breaks at Hyperthermic Temperatures in Chinese Hamster Ovary Cells. International Journal of Radiation Biology 61:1, pages 43-48.
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U. Weissenborn & G. Obe. (1991) Modification of X-ray Induced Chromosome Aberration Frequency by Pre- and Postirradiation Hyperthermia of Human Peripheral Lymphocytes. International Journal of Radiation Biology 59:4, pages 973-984.
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E. Dikomey & H. Jung. (1991) Thermal Radiosensitization in CHO Cells by Prior Heating at 41–46°C. International Journal of Radiation Biology 59:3, pages 815-825.
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Ian R. Radford & Sam Broadhurst. (1988) Aphidicolin Synchronization of Mouse L Cells Perturbs the Relationship between Cell Killing and DNA Double-strand Breakage after X-irradiation. International Journal of Radiation Biology 53:2, pages 205-215.
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Ian R. Radford. (1987) Effect of Cell-cycle Position and Dose on the Kinetics of DNA Double-strand Breakage Repair in X-irradiated Chinese Hamster Cells. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 52:4, pages 555-563.
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F.H.A. Schneeweiss, G. Tisljar-Lentulis, K. Haustein & L.E. Feinendegen. (1987) ‘Periodical’ Pattern of Kinetics of DNA Strand Break Repair Following γ-irradiation of Human T1-cells. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 52:3, pages 491-493.
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Ian R. Radford & George S. Hodgson. (1987) Effect of Ploidy on the Response of V79 Cells to Ionizing Radiation. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 51:5, pages 765-778.
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R.L. Warters, B.W. Lyons & J. Axtell-Bartlett. (1987) Inhibition of Repair of Radiation-induced DNA Damage by Thermal Shock in Chinese Hamster Ovary Cells. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 51:3, pages 505-517.
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Therese M. Coquerelle, Karl F. Weibezahn & Christine Lücke-Huhle. (1987) Rejoining of Double Strand Breaks in Normal Human and Ataxia-telangiectasia Fibroblasts after Exposure to 60Co γ-rays, 241Am α-particles or Bleomycin. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 51:2, pages 209-218.
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Ekkehard Dikomey & Jochen Franzke. (1986) Three Classes of DNA Strand Breaks Induced by X-irradiation and Internal β-rays. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 50:5, pages 893-908.
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Ian R. Radford. (1985) Effect of Radiomodifying Agents on the Ratios of X-ray-induced Lesions in Cellular DNA: Use in Lethal Lesion Determination. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 49:4, pages 621-637.
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Ian R. Radford. (1985) Evidence for a General Relationship between the Induced Level of DNA Double-strand Breakage and Cell-killing after X-irradiation of Mammalian Cells. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 49:4, pages 611-620.
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Ian R. Radford & George S. Hodgson. (1985) 125I-induced DNA Double Strand Breaks: Use in Calibration of the Neutral Filter Elution Technique and Comparison with X-ray Induced Breaks. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 48:4, pages 555-566.
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Ian R. Radford. (1985) The Level of Induced DNA Double-strand Breakage Correlates with Cell Killing after X-irradiation. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 48:1, pages 45-54.
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Articles from other publishers (19)

Joy E. Garrett, Joy E. Garrett, Erin Metzger, Katelyn Schmitt, Sarai Soto, Samantha Northern, Laura Kryah, Misbah Irfan, Susan Rice, Mary Brown, Jeffrey M. Zaleski & Joseph R. Dynlacht. (2019) Enhancement of Cytotoxicity of Enediyne Compounds by Hyperthermia: Effects of Various Metal Complexes on Tumor Cells. Radiation Research 193:2, pages 107.
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Eric J. Keller, Meghan Porter, Joy E. Garrett, Meredith Varie, Haiyan Wang, Karen E. Pollok, John J. Turchi, Jeffrey M. Zaleski & Joseph R. Dynlacht. (2018) Characterization of Thermally Activated Metalloenediyne Cytotoxicity in Human Melanoma Cells. Radiation Research 190:2, pages 107-116.
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Defeng Qi, Yuan Hu, Jinhui Li, Tao Peng, Jialin Su, Yun He & Weidong Ji. (2015) Hyperthermia Induces Apoptosis of 786-O Cells through Suppressing Ku80 Expression. PLOS ONE 10:4, pages e0122977.
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Bogdan I. Gerashchenko, Gerirose Gooding & Joseph R. Dynlacht. (2010) Hyperthermia alters the interaction of proteins of the Mre11 complex in irradiated cells. Cytometry Part A 77A:10, pages 940-952.
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Joshua D. Seno & Joseph R. Dynlacht. (2004) Intracellular redistribution and modification of proteins of the Mre11/Rad50/Nbs1 DNA repair complex following irradiation and heat-shock. Journal of Cellular Physiology 199:2, pages 157-170.
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Masanobu HAYASHI, Taku HAMASU, Daiji ENDOH, Ai KAWANA, Minako MATSUMOTO & Toyo OKUI. (2004) High Sensitivity of Fibroblast Cell Lines Derived from LEC Rats to Heat Treatment. Journal of Veterinary Medical Science 66:10, pages 1177-1182.
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Joseph R. Dynlacht, M. Eric Bittner, Jody A. Bethel & Brian D. Beck. (2003) The non‐homologous end‐joining pathway is not involved in the radiosensitization of mammalian cells by heat shock. Journal of Cellular Physiology 196:3, pages 557-564.
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Björn Cedervall, Margareta R. Edgren & Rolf Lewensohn. (2003) X-Ray-Induced DNA Double-Strand Breaks in Mouse L1210 Cells: A New Computational Method for Analyzing Neutral Filter Elution Data. Radiation Research 159:4, pages 495-501.
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Wei-Guo Zhu, Joshua D. Seno, Brian D. Beck & Joseph R. Dynlacht. (2001) Translocation of MRE11 from the Nucleus to the Cytoplasm as a Mechanism of Radiosensitization by Heat 1 . Radiation Research 156:1, pages 95-102.
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E. Dikomey. 1994. Advances in Mutagenesis Research. Advances in Mutagenesis Research 135 163 .
M. Frankenberg-Schwager. 1993. Biological Effects and Physics of Solar and Galactic Cosmic Radiation. Biological Effects and Physics of Solar and Galactic Cosmic Radiation 1 31 .
M. R. Horsman & J. Overgaard. 1992. Interstitial Hyperthermia. Interstitial Hyperthermia 11 33 .
Michael C. Elia, John G. DeLuca & Matthews O. Bradley. (1991) Significance and measurement of DNA double strand breaks in mammalian cells. Pharmacology & Therapeutics 51:3, pages 291-327.
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C. Streffer. 1990. Biological Basis of Oncologic Thermotherapy. Biological Basis of Oncologic Thermotherapy 1 71 .
William D. Wright, Ryuji Higashikubo & Joseph L. Roti Roti. (1989) Flow cytometric studies of the nuclear matrix. Cytometry 10:3, pages 303-311.
Crossref
Ruth C. Moore, Chris Randell & M.A. Bender. (1988) An investigation using inhibition of G2 repair of the molecular basis of lesions which result in chromosomal aberrations. Mutation Research/Environmental Mutagenesis and Related Subjects 199:1, pages 229-233.
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Ruth C. Moore, Chris Randell & M.A. Bender. (1988) An investigation using inhibition of G2 repair of the molecular basis of lesions which result in chromosomal aberrations. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 199:1, pages 229-233.
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G.P. Raaphorst & E.I. Azzam. (1986) Thermotolerance and thermal sensitization in a differentiating murine erythroleukemia cell line. Journal of Thermal Biology 11:1, pages 17-23.
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G.P. Raaphorst & E.I. Azzam. (1985) Hyperthermia enhances x ray cell killing in normal and homozygous and heterozygous ataxia telangiectasia human cells. International Journal of Radiation Oncology*Biology*Physics 11:4, pages 855-859.
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