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Original Article

Radiosensitization of Chinese Hamster Cells by Oxygen and Misonidazole at Low X-ray Doses

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Pages 1009-1021 | Received 17 Mar 1986, Accepted 01 Jul 1986, Published online: 03 Jul 2009

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Alexandru Daşu & Iuliana Toma-Daşu. (2008) Treatment modelling: The influence of micro-environmental conditions. Acta Oncologica 47:5, pages 896-905.
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P. Lambin, B. Marples, B. Fertil, E.P. Malaise & M.C. Joiner. (1993) Hypersensitivity of a Human Tumour Cell Line to Very Low Radiation Doses. International Journal of Radiation Biology 63:5, pages 639-650.
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R.J. Hodgkiss, E. Kelleher & J. Parrick. (1992) Hypoxia-specific Inhibition of Recovery from Radiation Damage by a Novel 2-nitroimidazole with a Theophylline Side Chain. International Journal of Radiation Biology 61:6, pages 797-803.
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I. Spadinger & B. Palcic. (1992) The Relative Biological Effectiveness of 60Co γ-rays, 55 kVp X-rays, 250 kVp X-rays, and 11 MeV Electrons at Low Doses. International Journal of Radiation Biology 61:3, pages 345-353.
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O. Sapora, F. Barone, M. Belli, A. Maggi, M. Quintiliani & M.A. Tabocchini. (1991) Relationships Between Cell Killing, Mutation Induction and DNA Damage in X-irradiated V79 Cells: The Influence of Oxygen and DMSO. International Journal of Radiation Biology 60:3, pages 467-482.
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M.E. Watts, M.F. Dennis & I.J. Roberts. (1990) Radiosensitization by Misonidazole, Pimonidazole and Azomycin and Intracellular Uptake in Human Tumour Cell Lines. International Journal of Radiation Biology 57:2, pages 361-372.
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Articles from other publishers (32)

Chun-Chieh Chan, Fang-Hsin Chen, Kuang-Lung Hsueh & Ya-Yun Hsiao. (2022) The Effect of Hypoxia on Relative Biological Effectiveness and Oxygen Enhancement Ratio for Cells Irradiated with Grenz Rays. Cancers 14:5, pages 1262.
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Hongyu Zhu, Junli Li, Xiaowu Deng, Rui Qiu, Zhen Wu & Hui Zhang. (2021) Development of a DNA damage model that accommodates different cellular oxygen concentrations and radiation qualities. Medical Physics 48:9, pages 5511-5521.
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Chaoming Wang, An Sun, Yong Qiao, Peipei Zhang, Liyuan Ma & Ming Su. (2015) Cationic surface modification of gold nanoparticles for enhanced cellular uptake and X-ray radiation therapy. J. Mater. Chem. B 3:37, pages 7372-7376.
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Tatiana Wenzl & Jan J Wilkens. (2011) Theoretical analysis of the dose dependence of the oxygen enhancement ratio and its relevance for clinical applications. Radiation Oncology 6:1.
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Robert D. Stewart, Victor K. Yu, Alexandros G. Georgakilas, Constantinos Koumenis, Joo Han Park & David J. Carlson. (2011) Effects of Radiation Quality and Oxygen on Clustered DNA Lesions and Cell Death. Radiation Research 176:5, pages 587-602.
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Tatiana Wenzl & Jan J Wilkens. (2011) Modelling of the oxygen enhancement ratio for ion beam radiation therapy. Physics in Medicine and Biology 56:11, pages 3251-3268.
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Grant D. Stewart, Jyoti Nanda, Elad Katz, Karen J. Bowman, Jill G. Christie, D.J. Gordon Brown, Duncan B. McLaren, Antony C.P. Riddick, James A. Ross, George D.D. Jones & Fouad K. Habib. (2011) DNA strand breaks and hypoxia response inhibition mediate the radiosensitisation effect of nitric oxide donors on prostate cancer under varying oxygen conditions. Biochemical Pharmacology 81:2, pages 203-210.
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P. Wardman. (2007) Chemical Radiosensitizers for Use in Radiotherapy. Clinical Oncology 19:6, pages 397-417.
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Peter Wardman, Kai Rothkamm, Lisa K. Folkes, Michael Woodcock & Peter J. Johnston. (2007) Radiosensitization by Nitric Oxide at Low Radiation Doses. Radiation Research 167:4, pages 475-484.
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J Z Wang, X A Li & N A Mayr. (2006) Dose escalation to combat hypoxia in prostate cancer: a radiobiological study on clinical data. The British Journal of Radiology 79:947, pages 905-911.
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Alexandru Daşu & Juliana Denekamp. (2000) Inducible Repair and Intrinsic Radiosensitivity: A Complex but Predictable Relationship?. Radiation Research 153:3, pages 279-288.
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Alexandru Daşu & Juliana Denekamp. (1999) Superfractionation as a potential hypoxic cell radiosensitizer: prediction of an optimum dose per fraction. International Journal of Radiation Oncology*Biology*Physics 43:5, pages 1083-1094.
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Juliana Denekamp, Alexandru DaŞu, Anthony Waites & Bo Littbrand. (1998) Hyperfractionation as an effective way of overcoming radioresistance. International Journal of Radiation Oncology*Biology*Physics 42:4, pages 705-709.
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Alexandru Daşu & Juliana Denekamp. (1998) New insights into factors influencing the clinically relevant oxygen enhancement ratio. Radiotherapy and Oncology 46:3, pages 269-277.
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Kirsten A. Skov & Susan Macphail. (1994) Low concentrations of nitroimidazoles: Effective radiosensitizers at low doses. International Journal of Radiation Oncology*Biology*Physics 29:1, pages 87-93.
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K. Ono, S. Masunaga, K. Akuta & M. Akaboshi. (1994) Middle dose rate irradiation in combination with carbogen inhalation selectively and more markedly increases the responses of SCCVII tumors. International Journal of Radiation Oncology*Biology*Physics 29:1, pages 81-85.
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Kirsten Skov & Brian Marples. (2006) Increased radioresistance at clinical doses: Investigations from the survival perspective . Radiation Oncology Investigations 2:5, pages 201-211.
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Kirsten A. Skov, Cameron J. Koch & Brian Marples. (2006) Effect of etanidazole on absolute sensitivity and increased radioresistance in hypoxic cells at low doses. Radiation Oncology Investigations 2:4, pages 164-170.
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Yee-Min Jen & Jolyon H. Hendry. (1993) Dose-fractionation sensitivity of mouse kidney clonogens measured using different interfraction intervals and postirradiation assay times. Radiotherapy and Oncology 26:2, pages 117-124.
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M. C. Joiner, B. Marples & H. Johns. 1993. Current Topics in Clinical Radiobiology of Tumors. Current Topics in Clinical Radiobiology of Tumors 51 66 .
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Kirsten A. Skov & H. Susan MacPhail. (1992) Effect of bso on the radiation response at low (0–4 Gy) doses. International Journal of Radiation Oncology*Biology*Physics 22:3, pages 533-536.
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M. E. Watts & M. Woodcock. (1991) Radiosensitization of Chinese hamster cells by pimonidazole (Ro 03–8799) at low X-ray doses. The British Journal of Radiology 64:766, pages 971-974.
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Kirsten Skov & Susan Macphail. (1991) Interaction of platinum drugs with clinically relevant X-ray doses in mammalian cells: A comparison of cisplatin, carboplatin, iproplatin, and tetraplatin. International Journal of Radiation Oncology*Biology*Physics 20:2, pages 221-225.
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O. C. A. Scott. (1990) Mathematical models of repopulation and reoxygenation in radiotherapy. The British Journal of Radiology 63:754, pages 821-823.
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R.G. Bristow, P.A. Hardy & R.P. Hill. (1990) Comparison between in vitro radiosensitivity and in vivo radioresponse of murine tumor cell lines I: parameters of in vitro radiosensitivity and endogenous cellular glutathione levels. International Journal of Radiation Oncology*Biology*Physics 18:1, pages 133-145.
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R. J. Yaes. (1988) The linear-quadratic model. The British Journal of Radiology 61:728, pages 703-704.
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Helen B. Stone. (1988) Misonidazole in fractionated radiotheraphy of a murine mammary carcinoma: Comparison of tumor and normal tissue response. International Journal of Radiation Oncology*Biology*Physics 14:5, pages 957-962.
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John E Moulder, Jean Dutreix, Sara Rockwell & Dietmar W Siemann. (1988) Applicability of animal tumor data to cancer therapy in humans. International Journal of Radiation Oncology*Biology*Physics 14:5, pages 913-927.
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Peter Wardman. (1987) The mechanism of radiosensitization by electron-affinic compounds. International Journal of Radiation Applications and Instrumentation. Part C. Radiation Physics and Chemistry 30:5-6, pages 423-432.
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