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Original Article

Hydroxyl Radical-induced Strand Break Formation of Poly(U) in Anoxic Solution. Effect of Dithiothreitol and Tetranitromethane

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Pages 319-330 | Received 23 May 1986, Accepted 18 Aug 1986, Published online: 03 Jul 2009

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Miral Dizdaroglu & Pawel Jaruga. (2012) Mechanisms of free radical-induced damage to DNA. Free Radical Research 46:4, pages 382-419.
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S.A. Grachev, E.V. Kropachev & G.I. Litvjakova. (1995) Formation of 5-hydroxy-5,6-dihydrouracil and Release of Undamaged Uracil as a Result of Poly(U) Irradiation in N2O-saturated Aqueous Solution. International Journal of Radiation Biology 68:5, pages 543-551.
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H.C. Box, E.E. Budzinski, H.G. Freund, M.S. Evans, H.B. Patrzyc, J.C. Wallace & A.E. Maccubbin. (1993) Vicinal Lesions in X-irradiated DNA?. International Journal of Radiation Biology 64:3, pages 261-263.
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L. Denison, A. Haigh, G. D'cunha & R.F. Martin. (1992) DNA Ligands as Radioprotectors: Molecular Studies with Hoechst 33342 and Hoechst 33258. International Journal of Radiation Biology 61:1, pages 69-81.
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M. Liphard, E. Bothe & D. Schulte-Frohlinde. (1990) The Influence of Glutathione on Single-strand Breakage in Single-stranded DNA Irradiated in Aqueous Solution in the Absence and Presence of Oxygen. International Journal of Radiation Biology 58:4, pages 589-602.
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G.D.D. Jones & P. O'Neill. (1990) The Kinetics of Radiation-induced Strand Breakage in Polynucleotides in the Presence of Oxygen: A Time-resolved Light-scattering Study. International Journal of Radiation Biology 57:6, pages 1123-1139.
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Eberhard Bothe, Mundra Adinarayana & Dietrich Schulte-Frohlinde. (1989) Rate and Yield of Oh-Induced Strand Break Formation of Polynucleotides and DNA. Free Radical Research Communications 6:2-3, pages 139-139.
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K. Hildenbrand & D. Schulte-Frohlinde. (1989) E.s.r. Studies on the Mechanism of Hydroxyl Radical-induced Strand Breakage of Polyuridylic Acid. International Journal of Radiation Biology 55:5, pages 725-738.
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A.M. Önal, D.G.E. Lemaire, E. Bothe & D. Schulte-Frohlinde. (1988) γ-Radiolysis of Poly(A) in Aqueous Solution: Efficiency of Strand Break Formation by Primary Water Radicals. International Journal of Radiation Biology 53:5, pages 787-796.
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Ian R. Radford. (1987) Use of ‘Nuclear Monolayers’ to Identify Factors Influencing DNA Double-Strand Breakage by X-rays. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine 52:6, pages 853-858.
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Articles from other publishers (22)

Rakesh Paul & Marc M. Greenberg. (2016) Mechanistic Studies on RNA Strand Scission from a C2′-Radical. The Journal of Organic Chemistry 81:19, pages 9199-9205.
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Marino J. E. Resendiz, Venkata Pottiboyina, Michael D. Sevilla & Marc M. Greenberg. (2012) Direct Strand Scission in Double Stranded RNA via a C5-Pyrimidine Radical. Journal of the American Chemical Society 134:8, pages 3917-3924.
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Harold C Box, Jean B Dawidzik & Edwin E Budzinski. (2001) Free radical-induced double lesions in DNA. Free Radical Biology and Medicine 31:7, pages 856-868.
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Marc M. Greenberg. 1999. Comprehensive Natural Products Chemistry. Comprehensive Natural Products Chemistry 371 425 .
P. O'Neill. (1994) The role of hydration and radiation quality in the induction of DNA damage-chemical aspects. Advances in Space Research 14:10, pages 221-234.
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Piotr Ulanski, Eberhard Bothe, Janusz M. Rosiak & Clemens von Sonntag. (2003) OH‐radical‐induced crosslinking and strand breakage of poly(vinyl alcohol) in aqueous solution in the absence and presence of oxygen. A pulse radiolysis and product study. Macromolecular Chemistry and Physics 195:4, pages 1443-1461.
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Peter O'neill & E. Martin Fielden. 1993. Advances in Radiation Biology - DNA and Chromatin Damage Caused by Radiation. Advances in Radiation Biology - DNA and Chromatin Damage Caused by Radiation 53 120 .
Helmut Görner, Malgorzata Wala & Dietrich Schulte‐Frohlinde. (2008) STRAND BREAKAGE IN POLY(C), POLY(A), SINGLE‐AND DOUBLE‐STRANDED DNA INDUCED BY NANOSECOND LASER EXCITATION AT 193 nm*. Photochemistry and Photobiology 55:2, pages 173-184.
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Clemens von Sonntag & Heinz‐Peter Schuchmann. (2003) The Elucidation of Peroxyl Radical Reactions in Aqueous Solution with the Help of Radiation‐Chemical Methods. Angewandte Chemie International Edition in English 30:10, pages 1229-1253.
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Clemens von Sonntag & Heinz-Peter Schuchmann. (1991) Aufklärung von Peroxyl-Radikalreaktionen in wäßriger Lösung mit strahlenchemischen Techniken. Angewandte Chemie 103:10, pages 1255-1279.
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Peter Wardman. 1991. The Early Effects of Radiation on DNA. The Early Effects of Radiation on DNA 249 264 .
Roman Osman, Karol Miaskiewicz & Harel Weinstein. 1992. Physical and Chemical Mechanisms in Molecular Radiation Biology. Physical and Chemical Mechanisms in Molecular Radiation Biology 423 452 .
Clemens von Sonntag. 1991. Physical and Chemical Mechanisms in Molecular Radiation Biology. Physical and Chemical Mechanisms in Molecular Radiation Biology 287 321 .
D. Schulte-Frohlinde, M. G. Simic & H. Görner. (1990) LASER-INDUCED STRAND BREAK FORMATION IN DNA and POLYNUCLEOTIDES. Photochemistry and Photobiology 52:6, pages 1137-1151.
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Eberhard Bothe, Helmut Gorner, Joachim Opitz, Dietrich Schulte‐Frohlinde, Aslam Siddiqi & Malgorzata Wala. (2008) SINGLE‐ and DOUBLE‐STRAND BREAK FORMATION IN DOUBLE‐STRANDED DNA UPON NANOSECOND LASER‐INDUCED PHOTOIONIZATION. Photochemistry and Photobiology 52:5, pages 949-959.
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Małgorzata Wala, Eberhard Bothe, Helmut Görner & Dietrich Schulte-Frohlinde. (1990) Quantum yields for the generation of hydrated electrons and single-strand breaks in poly(C), poly(A) and single-stranded DNA in aqueous solution on 20 ns laser excitation at 248 nm. Journal of Photochemistry and Photobiology A: Chemistry 53:1, pages 87-108.
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Clemens von Sonntag & Heinz-Peter Schuchmann. 1990. Sulfur-Centered Reactive Intermediates in Chemistry and Biology. Sulfur-Centered Reactive Intermediates in Chemistry and Biology 409 414 .
Alessandro B. Tossi, Helmut Görner & Dietrich Schulte‐Frohlinde. (2008) PHOTOSENSITIZED REACTIONS OF POLY(U) WITH TRIS(2,2′ BIPYRIDYL)RUTHENIUM(II) AND PEROXYDISULFATE. Photochemistry and Photobiology 50:5, pages 585-597.
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S. A. Grachev, E. V. Kropachev & G. I. Litvyakova. (1988) Hydrogen atom transfer reactions from the SH group of thiols to OH adducts to uracil during radiolysis. Bulletin of the Academy of Sciences of the USSR Division of Chemical Science 37:12, pages 2472-2477.
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E. Bothe, M. Adinarayana & D. Schulte-Frohlinde. 1988. Organic Free Radicals. Organic Free Radicals 11 11 .
Joachim Opitz & Dietrich Schulte-Frohlinde. (1987) Laser-induced photoionization and single-strand break formation for polynucleotides and single-stranded DNA in aqueous solution: model studies for the direct effect of high energy radiation on DNA. Journal of Photochemistry 39:1, pages 145-163.
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Peter Wardman. (1987) The mechanism of radiosensitization by electron-affinic compounds. International Journal of Radiation Applications and Instrumentation. Part C. Radiation Physics and Chemistry 30:5-6, pages 423-432.
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