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Original Article

The Irradiation of V79 Mammalian Cells by Protons with Energies below 2 MeV

Part I: Experimental Arrangement and Measurements of Cell Survival

, , , , &
Pages 221-237 | Received 06 Feb 1989, Accepted 06 May 1989, Published online: 03 Jul 2009

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Tordis J. Dahle, Anne Marit Rykkelid, Camilla H. Stokkevåg, Andrea Mairani, Andreas Görgen, Nina J. Edin, Eivind Rørvik, Lars Fredrik Fjæra, Eirik Malinen & Kristian S. Ytre-Hauge. (2017) Monte Carlo simulations of a low energy proton beamline for radiobiological experiments. Acta Oncologica 56:6, pages 779-786.
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Venkata S. K. Manem, Mohammad Kohandel, David C. Hodgson, Michael B. Sharpe & Siv Sivaloganathan. (2015) The effect of radiation quality on the risks of second malignancies. International Journal of Radiation Biology 91:3, pages 209-217.
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Brita Singers Sørensen, Jens Overgaard & Niels Bassler. (2011) In vitro RBE-LET dependence for multiple particle types. Acta Oncologica 50:6, pages 757-762.
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C Leloup, G Garty, G Assaf, A Cristovão, A Breskin, R Chechik, S Shchemelinin, T Paz-Elizur, Z Livneh, RW Schulte, V Bashkirov, JR Milligan & B Grosswendt. (2005) Evaluation of lesion clustering in irradiated plasmid DNA. International Journal of Radiation Biology 81:1, pages 41-54.
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M. FOLKARD. (1996) Inactivation of V79 cells by low-energy protons, deuterons and helium-3 ions. International Journal of Radiation Biology 69:6, pages 729-738.
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M.R. Raju. (1995) Proton Radiobiology, Radiosurgery and Radiotherapy. International Journal of Radiation Biology 67:3, pages 237-259.
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M. Belli, F. Cera, R. Cherubini, F. Ianzini, G. Moschini, O. Sapora, G. Simone, M.A. Tabocchini & P. Tiveron. (1994) DNA Double-strand Breaks Induced by Low Energy Protons in V79 Cells. International Journal of Radiation Biology 65:5, pages 529-536.
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K.M. Prise. (1994) Use of Radiation Quality as a Probe for DNA Lesion Complexity. International Journal of Radiation Biology 65:1, pages 43-48.
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D.E. Charlton & B.J. Allen. (1993) Monte Carlo Calculations of Ion Passages Through Brain Endothelial Nuclei During Boron Neutron Capture Therapy. International Journal of Radiation Biology 64:6, pages 739-747.
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M. Belli, F. Cera, R. Cherubini, A.M.I. Haque, F. Ianzini, G. Moschini, O. Sapora, G. Simone, M.A. Tabocchini & P. Tiveron. (1993) Inactivation and Mutation Induction in V79 Cells by Low Energy Protons: Re-evaluation of the Results at the LNL Facility. International Journal of Radiation Biology 63:3, pages 331-337.
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T.J. Jenner, M. Belli, D.T. Goodhead, F. Ianzini, G. Simone & M.A. Tabocchini. (1992) Direct Comparison of Biological Effectiveness of Protons and Alpha-particles of the Same LET. III. Initial Yield of DNA Double-strand Breaks in V79 Cells. International Journal of Radiation Biology 61:5, pages 631-637.
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M. Belli, D.T. Goodhead, F. Ianzini, G. Simone & M.A. Tabocchini. (1992) Direct Comparison of Biological Effectiveness of Protons and Alpha-particles of the Same LET. II. Mutation Induction at the HPRT Locus in V79 Cells. International Journal of Radiation Biology 61:5, pages 625-629.
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D.T. Goodhead, M. Belli, A.J. Mill, D.A. Bance, L.A. Allens, S.C. Hall, F. Ianzani, G. Simone, D.L. Stevens, A. Stretch, M.A. Tabocchini & R.E. Wilkinson. (1992) Direct Comparison between Protons and Alpha-particles of the Same LET: I. Irradiation Methods and Inactivation of Asynchronous V79, HeLa and C3H 10T½ Cells. International Journal of Radiation Biology 61:5, pages 611-624.
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M. Belli, F. Cera, R. Cherubini, F. Ianzini, G. Moschini, O. Sapora, G. Simone, M.A. Tabocchini & P. Tiveron. (1991) Mutation Induction and RBE-LET Relationship of Low-energy Protons in V79 Cells. International Journal of Radiation Biology 59:2, pages 459-465.
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J.Y. Ostashevsky. (1990) Prediction of Cell Survival Curves from DNA Double-strand Break Repair Data for Low- and High-LET Radiation. International Journal of Radiation Biology 57:3, pages 523-536.
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K.M. Prise, M. Folkard, S. Davies & B.D. Michael. (1990) The Irradiation of V79 Mammalian Cells by Protons with Energies below 2 MeV. Part II. Measurement of Oxygen Enhancement Ratios and DNA Damage. International Journal of Radiation Biology 58:2, pages 261-277.
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