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International Journal of Radiation Biology Volume 61, 1992 - Issue 4
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Original Article

Haematological Effects of RhGM-CSF in Dogs Exposed to Total-body Irradiation with a Dose of 2·4 Gy

W. Nothdurft Institute of Occupational and Social Medicine, University of Ulm, Ulm, Federal Republic of Germany
,
C. Selig Research Laboratories of Behringwerke AG, Marburg, Federal Republic of Germany
,
T.M. Fliedner Institute of Occupational and Social Medicine, University of Ulm, Ulm, Federal Republic of Germany
,
P. Hintz-Obertreis Research Laboratories of Behringwerke AG, Marburg, Federal Republic of Germany
,
L. Kreja Institute of Occupational and Social Medicine, University of Ulm, Ulm, Federal Republic of Germany
,
D. Krumwieh Research Laboratories of Behringwerke AG, Marburg, Federal Republic of Germany
,
R. Kurrle Institute of Occupational and Social Medicine, University of Ulm, Ulm, Federal Republic of Germany
,
F.R. Seiler Research Laboratories of Behringwerke AG, Marburg, Federal Republic of Germany
&
W. Weinsheimer Institute of Occupational and Social Medicine, University of Ulm, Ulm, Federal Republic of Germany
 show all
Pages 519-531 | Received 11 Apr 1991, Accepted 07 Oct 1991, Published online: 03 Jul 2009

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Read on this site (4)

Vijay K. Singh & Thomas M. Seed. (2021) Radiation countermeasures for hematopoietic acute radiation syndrome: growth factors, cytokines and beyond. International Journal of Radiation Biology 97:11, pages 1526-1547.
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Vijay K. Singh, Melissa Garcia & Thomas M. Seed. (2017) A review of radiation countermeasures focusing on injury-specific medicinals and regulatory approval status: part II. Countermeasures for limited indications, internalized radionuclides, emesis, late effects, and agents demonstrating efficacy in large animals with or without FDA IND status. International Journal of Radiation Biology 93:9, pages 870-884.
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Vijay K. Singh & Thomas M. Seed. (2017) A review of radiation countermeasures focusing on injury-specific medicinals and regulatory approval status: part I. Radiation sub-syndromes, animal models and FDA-approved countermeasures. International Journal of Radiation Biology 93:9, pages 851-869.
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Vijay K Singh, Victoria L Newman, Patricia LP Romaine, Stephen Y Wise & Thomas M Seed. (2014) Radiation countermeasure agents: an update (2011 – 2014). Expert Opinion on Therapeutic Patents 24:11, pages 1229-1255.
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Articles from other publishers (17)

M. V. Vasin & I. B. Ushakov. (2020) Potential Ways to Increase Body Resistance to Damaging Action of Ionizing Radiation with Radiomitigators. Biology Bulletin Reviews 9:6, pages 503-519.
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Y. Zhang, S. Axiak-Bechtel, C. Friedman Cowan, J. Amorim, K. Tsuruta & A. E. DeClue. (2017) Evaluation of immunomodulatory effect of recombinant human granulocyte-macrophage colony-stimulating factor on polymorphonuclear cell from dogs with cancer in vitro . Veterinary and Comparative Oncology 15:3, pages 968-979.
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Merriline Satyamitra, Vidya P. Kumar, Shukla Biswas, Lynnette Cary, Leonora Dickson, Srinivasan Venkataraman & Sanchita P. Ghosh. (2017) Impact of Abbreviated Filgrastim Schedule on Survival and Hematopoietic Recovery after Irradiation in Four Mouse Strains with Different Radiosensitivity. Radiation Research 187:6, pages 659.
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Vijay K. Singh, Victoria L. Newman & Thomas M. Seed. (2015) Colony-stimulating factors for the treatment of the hematopoietic component of the acute radiation syndrome (H-ARS): A review. Cytokine 71:1, pages 22-37.
Crossref
Kazuhide NAKAGAKI, Yuka NUNOMURA, Kanji UCHIDA, Koh NAKATA & Ryushi TAZAWA. (2014) Up-Regulation of Cluster of Differentiation (CD) 11b Expression on the Surface of Canine Granulocytes with Human Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF). Journal of Veterinary Medical Science 76:8, pages 1173-1176.
Crossref
Maria Moroni, Barbara F. Ngudiankama, Christine Christensen, Cara H. Olsen, Rossitsa Owens, Eric D. Lombardini, Rebecca K. Holt & Mark H. Whitnall. (2013) The Gottingen Minipig Is a Model of the Hematopoietic Acute Radiation Syndrome: G-Colony Stimulating Factor Stimulates Hematopoiesis and Enhances Survival From Lethal Total-Body ?-Irradiation. International Journal of Radiation Oncology*Biology*Physics 86:5, pages 986-992.
Crossref
Maria Moroni, Eric Lombardini, Rudolph Salber, Mehdi Kazemzedeh, Vitaly Nagy, Cara Olsen & Mark H. Whitnall. (2011) Hematological Changes as Prognostic Indicators of Survival: Similarities Between Gottingen Minipigs, Humans, and Other Large Animal Models. PLoS ONE 6:9, pages e25210.
Crossref
Werner Klingler, Ludwika Kreja, Wilhelm Nothdurft & Christoph Selig. (2002) Influence of different radioprotective compounds on radiotolerance and cell cycle distribution of human progenitor cells of granulocytopoiesis in vitro . British Journal of Haematology 119:1, pages 244-254.
Crossref
David Murray & William H. McBride. 2001. Kirk-Othmer Encyclopedia of Chemical Technology. Kirk-Othmer Encyclopedia of Chemical Technology.
XUETAO CAO, RONG CAI, DIAN WEN JU, QUN TAO, YIZHI YU & JIANLI WANG. (1998) Augmentation of Hematopoiesis by Fibroblast-Mediated Interleukin-6 Gene Therapy in Mice with Chemotherapy. Journal of Interferon & Cytokine Research 18:4, pages 227-233.
Crossref
Xuetao Cao, Rong Cai, Dian Wen Ju, Qun Tao, Yizhi Yu & Jianli Wang. (1998) ACCELERATED RECOVERY OF IRRADIATION-INDUCED BONE MARROW DEPRESSION BY FIBROBLAST-MEDIATED INTERLEUKIN 6 GENE THERAPY IN COMBINATION WITH BONE MARROW TRANSPLANTATION IN MICE1. Transplantation 65:3, pages 325-331.
Crossref
Wilhelm Nothdurft, Ludwika Kreja & Christoph Selig. (1997) Acceleration of hemopoietic recovery in dogs after extended-field partial-body irradiation by treatment with colony-stimulating factors: rhG-CSF and rhGM-CSF. International Journal of Radiation Oncology*Biology*Physics 37:5, pages 1145-1154.
Crossref
C SeligW Nothdurft. (1995) Cytokines and progenitor cells of granulocytopoiesis in peripheral blood of patients with bacterial infections. Infection and Immunity 63:1, pages 104-109.
Crossref
T.M. Fliedner, W. Nothdurft, B. Tibken, E. Hofer, M. Weiss & H. Kindler. (1994) Haemopoietic cell renewal in radiation fields. Advances in Space Research 14:10, pages 541-554.
Crossref
Heinz Schmidberger, Clemens F Hess, Wolfgang Hoffmann, Monika A Reuss-Borst & Michael Bamberg. (1993) Granulocyte colony-stimulating factor treatment of leucopenia during fractionated radiotherapy. European Journal of Cancer 29:14, pages 1927-1931.
Crossref
F. von Bruchhausen, S. Ebel, E. Hackenthal, G. Dannhardt, A. W. Frahm, U. Holzgrabe, K. Keller, E. Nürnberg, H. Rimpler, G. Schneider, P. Surmann, H. U. Wolf & G. Wurm. 1993. Hagers Handbuch der Pharmazeutischen Praxis. Hagers Handbuch der Pharmazeutischen Praxis 319 399 .
Katharina H. I. Philipp, Patrick R. Gavin, Juan Casado, Axel Siefert, Raymond L. Moss & René Huiskamp. 1993. Advances in Neutron Capture Therapy. Advances in Neutron Capture Therapy 571 574 .

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