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Original Article

Mechanism of Radiosensitization by Halogenated Pyrimidines: The Contribution of Excess DNA and Chromosome Damage in BrdU Radiosensitization may be Minimal in Plateau-phase Cells

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Pages 133-142 | Received 13 Dec 1993, Accepted 29 Mar 1994, Published online: 03 Jul 2009

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Emran Heshmati, Parviz Abdolmaleki, Hossein Mozdarani & Amir Sabet Sarvestani. (2009) Effects of halogen substitution on Watson–Crick base pairing: A possible mechanism for radiosensitivity. Bioorganic & Medicinal Chemistry Letters 19:17, pages 5256-5260.
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Natalia D. Sumption, Dudley T. Goodhead & Rhona M. Anderson. (2006) No increase in radiation-induced chromosome aberration complexity detected by m-FISH after culture in the presence of 5′-bromodeoxyuridine. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 594:1-2, pages 30-38.
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Jean-Philippe Pignol, Eileen Rakovitch, David Beachey & Claude Le Sech. (2003) Clinical significance of atomic inner shell ionization (ISI) and Auger cascade for radiosensitization using IUdR, BUdR, platinum salts, or gadolinium porphyrin compounds. International Journal of Radiation Oncology*Biology*Physics 55:4, pages 1082-1091.
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Luka Milas, Kathryn A. Mason, Zhongxing Liao & Kian K. Ang. (2002) Chemoradiotherapy: Emerging treatment improvement strategies. Head & Neck 25:2, pages 152-167.
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Matthew M. Poggi, C.Norman Coleman & James B. Mitchell. (2001) Sensitizers and protectors of radiation and chemotherapy. Current Problems in Cancer 25:6, pages 334-411.
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NICOLAAS A. P. FRANKEN, CHRIS VAN BREE, MARTIJN A. T. VELTMAAT, HANS M. RODERMOND, JAAP HAVEMAN & GERRIT W. BARENDSEN. (2001) Radiosensitization by Bromodeoxyuridine and Hyperthermia: Analysis of Linear and Quadratic Parameters of Radiation Survival Curves of Two Human Tumor Cell Lines. Journal of Radiation Research 42:2, pages 179-190.
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Scott J Karnas, Edward Yu, Ronald C McGarry & Jerry J Battista. (1999) Optimal photon energies for IUdR K-edge radiosensitization with filtered x-ray and radioisotope sources. Physics in Medicine and Biology 44:10, pages 2537-2549.
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Chris Van Bree, Nicolaas A.P. Franken, Piet J.M. Bakker, Liana J. Klomp-Tukker, Gerrit W. Barendsen & J.Bart A. Kipp. (1997) Hyperthermia and incorporation of halogenated pyrimidines: Radiosensitization in cultured rodent and human tumor cells. International Journal of Radiation Oncology*Biology*Physics 39:2, pages 489-496.
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