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Research Article

Nucleobase transporters

Pages 75-94 | Published online: 09 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

James Leung, Alexander D Cameron, George Diallinas & Bernadette Byrne. (2013) Stabilizing the heterologously expressed uric acid-xanthine transporter UapA from the lower eukaryote . Molecular Membrane Biology 30:1, pages 32-42.
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Sotiris Amillis, Zsuzsanna Hamari, Sotiris Amillis, Zsuzsanna Hamari, Katerina Roumelioti, Claudio Scazzocchio & George Diallinas. (2007) Regulation of expression and kinetic modeling of substrate interactions of a uracil transporter in Aspergillus nidulans. Molecular Membrane Biology 24:3, pages 206-214.
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Sophia Goudela, Panayiota Karatza, Marina Koukaki, Stathis Frillingos & George Diallinas. (2005) Comparative substrate recognition by bacterial and fungal purine transporters of the NAT/NCS2 family. Molecular Membrane Biology 22:3, pages 263-275.
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Panayiota Karatza & Stathis Frillingos. (2005) Cloning and functional characterization of two bacterial members of the NAT/NCS2 family in Escherichia coli. Molecular Membrane Biology 22:3, pages 251-261.
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Soumyajit Majumdar, Sreeraj Macha, Dhananjay Pal & Ashim Mitra. (2004) Mechanism of ganciclovir uptake by rabbit retina and human retinal pigmented epithelium cell line ARPE-19. Current Eye Research 29:2-3, pages 127-136.
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Ralph J. Hyde, Carol E. Cass, James D. Young & James D. Stephen A. Baldwin. (2001) The ENT family of eukaryote nucleoside and nucleobase transporters: recent advances in the investigation of structure/function relationships and the identification of novel isoforms. Molecular Membrane Biology 18:1, pages 53-63.
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Marjan Ghasemi, Pulak Chandra Debnath, Byungjoo Kim, Marzieh Pournoury, Reza Khazaeinezhad, Sahar Hosseinzadeh Kassani, Dong-Il Yeom & Kyunghwan Oh. (2023) Highly nonlinear optic nucleic acid thin-solid film to generate short pulse laser. Scientific Reports 13:1.
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Lixue GUO, Lanjie ZHAO, Xuke LU, Xiugui CHEN, Shuai WANG, Junjuan WANG, Delong WANG, Zujun YIN, Chao CHEN, Yapeng FAN, Yuexin ZHANG & Wuwei YE. (2022) Characters and structures of the nucleobase–ascorbate transporters (NAT) family genes in Gossypium hirsutum and their roles in responding to salt and drought stresses. Journal of Cotton Research 5:1.
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Adeel Riaz, Fenglin Deng, Guang Chen, Wei Jiang, Qingfeng Zheng, Bisma Riaz, Michelle Mak, Fanrong Zeng & Zhong-Hua Chen. (2022) Molecular Regulation and Evolution of Redox Homeostasis in Photosynthetic Machinery. Antioxidants 11:11, pages 2085.
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Caitlin E Hatton, Deborah H Brotherton, Mahalah Spencer & Alexander D Cameron. (2022) Structure of cytosine transport protein CodB provides insight into nucleobase‐cation symporter 1 mechanism. The EMBO Journal 41:16.
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Manal J. Natto, Yukiko Miyamoto, Jane C. Munday, Tahani A. AlSiari, Mohammed I. Al‐Salabi, Neils B. Quashie, Anthonius A. Eze, Lars Eckmann & Harry P. De Koning. (2021) Comprehensive characterization of purine and pyrimidine transport activities in Trichomonas vaginalis and functional cloning of a trichomonad nucleoside transporter . Molecular Microbiology 116:6, pages 1489-1511.
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Wenlong Cai & Covadonga R. Arias. (2021) Deciphering the Molecular Basis for Attenuation of Flavobacterium columnare Strain Fc1723 Used as Modified Live Vaccine against Columnaris Disease. Vaccines 9:11, pages 1370.
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I.T. Gatchell, R.B. Huntley, N.P. Schultes & G.S. Mourad. (2020) The guanine–hypoxanthine permease GhxP of Erwinia amylovora facilitates the influx of the toxic guanine derivative 6‐thioguanine . Journal of Applied Microbiology 130:6, pages 2018-2028.
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Tingting Sun, Tingting Pei, Lulu Yang, Zhijun Zhang, Mingjun Li, Yuerong Liu, Fengwang Ma & Changhai Liu. (2021) Exogenous application of xanthine and uric acid and nucleobase-ascorbate transporter MdNAT7 expression regulate salinity tolerance in apple. BMC Plant Biology 21:1.
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Sho Wada, Norikazu Matsunaga & Ikumi Tamai. (2020) Mathematical modeling analysis of hepatic uric acid disposition using human sandwich-cultured hepatocytes. Drug Metabolism and Pharmacokinetics 35:5, pages 432-440.
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Hiroaki Yuasa, Tomoya Yasujima & Katsuhisa Inoue. (2020) Current Understanding of the Intestinal Absorption of Nucleobases and Analogs. Biological and Pharmaceutical Bulletin 43:9, pages 1293-1300.
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Risa Takenaka, Tomoya Yasujima, Junji Furukawa, Yosuke Hishikawa, Takahiro Yamashiro, Kinya Ohta, Katsuhisa Inoue & Hiroaki Yuasa. (2020) Functional Analysis of the Role of Equilibrative Nucleobase Transporter 1 (ENBT1/SLC43A3) in Adenine Transport in HepG2 Cells. Journal of Pharmaceutical Sciences 109:8, pages 2622-2628.
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Christine H. FoyerTina KyndtRobert D. Hancock. (2020) Vitamin C in Plants: Novel Concepts, New Perspectives, and Outstanding Issues. Antioxidants & Redox Signaling 32:7, pages 463-485.
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Barbara A. Fox & David J. Bzik. 2020. Toxoplasma gondii. Toxoplasma gondii 397 449 .
Sofia Dimou, Anezia Kourkoulou, Sotiris Amillis, Riccardo Percudani & George Diallinas. (2019) The peroxisomal SspA protein is redundant for purine utilization but essential for peroxisome localization in septal pores in Aspergillus nidulans. Fungal Genetics and Biology 132, pages 103259.
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Thomas Cheviet, Isabelle Lefebvre-Tournier, Sharon Wein & Suzanne Peyrottes. (2019) Plasmodium Purine Metabolism and Its Inhibition by Nucleoside and Nucleotide Analogues. Journal of Medicinal Chemistry 62:18, pages 8365-8391.
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Pratibha, Manjulika Shukla, Grace Kaul, Sidharth Chopra & Sandeep Verma. (2019) Nucleobase Soft Metallogel Composites with Antifouling Activities against ESKAPE Pathogens. ChemistrySelect 4:5, pages 1834-1839.
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Scott M. Jackson, Ekaterina Ivanova, Antonio N. Calabrese, Anna Polyakova, David J. Sharples, Tatsuro Shimamura, Florian Brueckner, Katie J. Simmons, Michelle Sahai, Homa Majd, Edmund Kunji, Irshad Ahmad, Simone Weyand, Shun’ichi Suzuki, Alison E. Ashcroft, Maria Kokkinidou, Arwen Pearson, Oliver Beckstein, Stephen A. Baldwin, So Iwata, Alexander D. Cameron & Peter J. F. Henderson. 2019. Encyclopedia of Biophysics. Encyclopedia of Biophysics 1 12 .
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Simon G Patching. (2018) Recent developments in nucleobase cation symporter-1 (NCS1) family transport proteins from bacteria, archaea, fungi and plants. Journal of Biosciences 43:4, pages 797-815.
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Wenbo Chai, Xiaojian Peng, Bin Liu, Jing Wang, Zhan Zhu, Yin Liu, Kai Zhao, Beijiu Cheng, Weina Si & Haiyang Jiang. (2018) Comparative Genomics, Whole-Genome Re-sequencing and Expression Profile Analysis of Nucleobase:Cation Symporter 2 (NCS2) Genes in Maize. Frontiers in Plant Science 9.
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Ioannis F. Kalampokis, George C. Kapetanakis, Konstantinos A. Aliferis & George Diallinas. (2018) Multiple nucleobase transporters contribute to boscalid sensitivity in Aspergillus nidulans. Fungal Genetics and Biology 115, pages 52-63.
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Li Qiu, Steven E. Patterson, Laurent F. Bonnac & Robert J. Geraghty. (2018) Nucleobases and corresponding nucleosides display potent antiviral activities against dengue virus possibly through viral lethal mutagenesis. PLOS Neglected Tropical Diseases 12:4, pages e0006421.
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Hiroshi Ashihara, Claudio Stasolla, Tatsuhito Fujimura & Alan Crozier. (2018) Purine salvage in plants. Phytochemistry 147, pages 89-124.
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Gustavo D. Campagnaro, Khalid J. Alzahrani, Jane C. Munday & Harry P. De Koning. (2018) Trypanosoma brucei bloodstream forms express highly specific and separate transporters for adenine and hypoxanthine; evidence for a new protozoan purine transporter family?. Molecular and Biochemical Parasitology 220, pages 46-56.
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Georgia F Papadaki, Sotiris Amillis & George Diallinas. (2017) Substrate Specificity of the FurE Transporter Is Determined by Cytoplasmic Terminal Domain Interactions. Genetics 207:4, pages 1387-1400.
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Katsuhisa Inoue. (2017) Molecular Basis of Nucleobase Transport Systems in Mammals. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 40:8, pages 1130-1138.
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Georgia Sioupouli, George Lambrinidis, Emmanuel Mikros, Sotiris Amillis & George Diallinas. (2017) Cryptic purine transporters in Aspergillus nidulans reveal the role of specific residues in the evolution of specificity in the NCS1 family . Molecular Microbiology 103:2, pages 319-332.
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Manuel Daumann, Philippe Golfier, Nathalie Knüppel, Matthias Hahn & Torsten Möhlmann. (2016) Botrytis cinerea can import and utilize nucleosides in salvage and catabolism and BcENT functions as high affinity nucleoside transporter. Fungal Biology 120:8, pages 904-916.
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Micah Rapp, Jessica Schein, Kevin A. Hunt, Vamsi Nalam, George S. Mourad & Neil P. Schultes. (2015) The solute specificity profiles of nucleobase cation symporter 1 (NCS1) from Zea mays and Setaria viridis illustrate functional flexibility. Protoplasma 253:2, pages 611-623.
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Tingting Sun, Dongfeng Jia, Linlin Huang, Yun Shao & Fengwang Ma. (2016) Comprehensive genomic identification and expression analysis of the nucleobase-ascorbate transporter (NAT) gene family in apple. Scientia Horticulturae 198, pages 473-481.
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Emilia Krypotou, Thomas Evangelidis, Jacob Bobonis, Alexandros A. Pittis, Toni Gabaldón, Claudio Scazzocchio, Emmanuel Mikros & George Diallinas. (2015) Origin, diversification and substrate specificity in the family of NCS1/FUR transporters. Molecular Microbiology 96:5, pages 927-950.
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Weike Duan, Xiaoming Song, Tongkun Liu, Zhinan Huang, Jun Ren, Xilin Hou, Jianchang Du & Ying Li. (2015) Patterns of Evolutionary Conservation of Ascorbic Acid-Related Genes Following Whole-Genome Triplication in Brassica rapa. Genome Biology and Evolution 7:1, pages 299-313.
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Christopher Girke, Manuel Daumann, Sandra Niopek-Witz & Torsten Möhlmann. (2014) Nucleobase and nucleoside transport and integration into plant metabolism. Frontiers in Plant Science 5.
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Emilia Krypotou, George Lambrinidis, Thomas Evangelidis, Emmanuel Mikros & George Diallinas. (2014) Modelling, substrate docking and mutational analysis identify residues essential for function and specificity of the major fungal purine transporter AzgA. Molecular Microbiology 93:1, pages 129-145.
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George Diallinas. (2013) Allopurinol and xanthine use different translocation mechanisms and trajectories in the fungal UapA transporter. Biochimie 95:9, pages 1755-1764.
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Emilia Krypotou, Vasiliki Kosti, Sotiris Amillis, Vassilios Myrianthopoulos, Emmanuel Mikros & George Diallinas. (2012) Modeling, Substrate Docking, and Mutational Analysis Identify Residues Essential for the Function and Specificity of a Eukaryotic Purine-Cytosine NCS1 Transporter. Journal of Biological Chemistry 287:44, pages 36792-36803.
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George S. Mourad, Julie Tippmann-Crosby, Kevin A. Hunt, Yvonne Gicheru, Kaely Bade, Tyler A. Mansfield & Neil P. Schultes. (2012) Genetic and molecular characterization reveals a unique nucleobase cation symporter 1 in Arabidopsis. FEBS Letters 586:9, pages 1370-1378.
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Zsuzsanna Hamari, Sotiris Amillis, Christine Drevet, Angeliki Apostolaki, Csaba Vágvölgyi, George Diallinas & Claudio Scazzocchio. (2009) Convergent evolution and orphan genes in the Fur4p-like family and characterization of a general nucleoside transporter in Aspergillus nidulans . Molecular Microbiology 73:1, pages 43-57.
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Anna Vlanti & George Diallinas. (2008) The Aspergillus nidulans FcyB cytosine-purine scavenger is highly expressed during germination and in reproductive compartments and is downregulated by endocytosis. Molecular Microbiology 68:4, pages 959-977.
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Sotiris Amillis, Marina Koukaki & George Diallinas. (2001) Substitution F569S converts UapA, a specific uric acid-xanthine transporter, into a broad specificity transporter for purine-related solutes. Journal of Molecular Biology 313:4, pages 765-774.
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