893
Views
26
CrossRef citations to date
0
Altmetric
Original

Aminopeptidase N (APN)/CD13-dependent CXCR4 downregulation is associated with diminished cell migration, proliferation and invasion

, , &
Pages 72-82 | Received 20 Nov 2006, Published online: 09 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Karthikeyan Subbarayan, Chiara Massa, Sandra Leisz, André Steven, Daniel Bethmann, Katharina Biehl, Claudia Wickenhauser & Barbara Seliger. (2022) Biglycan as a potential regulator of tumorgenicity and immunogenicity in K-RAS-transformed cells. OncoImmunology 11:1.
Read now
Karthikeyan Subbarayan, Sandra Leisz, Claudia Wickenhauser, Daniel Bethmann, Chiara Massa, André Steven & Barbara Seliger. (2018) Biglycan-mediated upregulation of MHC class I expression in HER-2/neu-transformed cells. OncoImmunology 7:4.
Read now

Articles from other publishers (24)

Guang Tan, Bing Li, YiJun Zhang, RengYin Zhang, Lin Wang, Fengjun Liu & Fei Shan. (2021) Targeted Fluorescence Imaging and Anti-Tumor Effects of QDs-NGR Nanoparticles on Pancreatic Cancer Cells. Science of Advanced Materials 13:12, pages 2475-2482.
Crossref
Yang Lu, Guangda Luo, Songbiao Zhu, Xu Wang, Yuling Chen, ZhouHuan Dong, Shiyu Wang, Jie Ma, Haiteng Deng, Di Wu & Jun Dong. (2020) The different expression of glycogen phosphorylases in renal clear cell renal carcinoma and chromophobe renal carcinoma. Clinical Proteomics 17:1.
Crossref
Dorian Forte, Daria Sollazzo, Martina Barone, Marisole Allegri, Angela di Martella Orsi, Marco Romano, Barbara Sinigaglia, Giuseppe Auteri, Nicola Vianelli, Michele Cavo, Francesca Palandri & Lucia Catani. (2018) Mobilized Peripheral Blood versus Cord Blood: Insight into the Distinct Role of Proinflammatory Cytokines on Survival, Clonogenic Ability, and Migration of CD34 + Cells . Mediators of Inflammation 2018, pages 1-14.
Crossref
Han-Yuan Liu, Hannah Grant, Hung-Lun Hsu, Raya Sorkin, Filip Bošković, Gijs Wuite & Susan Daniel. (2017) Supported Planar Mammalian Membranes as Models of in Vivo Cell Surface Architectures. ACS Applied Materials & Interfaces 9:41, pages 35526-35538.
Crossref
Astrid Veß, Ulrich Blache, Laura Leitner, Angela R. M. Kurz, Anja Ehrenpfordt, Michael Sixt & Guido Posern. (2017) A dual phenotype of MDA-MB-468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity. Journal of Cell Science 130:13, pages 2172-2184.
Crossref
Angelo Corti, Martina Fiocchi & Flavio Curnis. 2017. Next-Generation Therapies and Technologies for Immune-Mediated Inflammatory Diseases. Next-Generation Therapies and Technologies for Immune-Mediated Inflammatory Diseases 101 122 .
André Steven, Max Heiduk, Christian V. Recktenwald, Bernhard Hiebl, Claudia Wickenhauser, Chiara Massa & Barbara Seliger. (2015) Colorectal Carcinogenesis: Connecting K-RAS–Induced Transformation and CREB Activity In Vitro and In Vivo . Molecular Cancer Research 13:8, pages 1248-1262.
Crossref
Sandra Leisz, Kristin Schulz, Susanne Erb, Peter Oefner, Katja Dettmer, Dimitrios Mougiakakos, Ena Wang, Francesco M. Marincola, Franziska Stehle & Barbara Seliger. (2015) Distinct von Hippel-Lindau gene and hypoxia-regulated alterations in gene and protein expression patterns of renal cell carcinoma and their effects on metabolism. Oncotarget 6:13, pages 11395-11406.
Crossref
Rachel Morgan, Judith Endres, Nilofar Behbahani-Nejad, Kristine Phillips, Jeffrey H. Ruth, Sean C. Friday, Gautam Edhayan, Thomas Lanigan, Andrew Urquhart, Kevin C. Chung & David A. Fox. (2015) Expression and Function of Aminopeptidase N/CD13 Produced by Fibroblast-like Synoviocytes in Rheumatoid Arthritis: Role of CD13 in Chemotaxis of Cytokine-Activated T Cells Independent of Enzymatic Activity. Arthritis & Rheumatology 67:1, pages 74-85.
Crossref
André Steven, Sandra Leisz, Chiara Massa, Manuela Iezzi, Rossano Lattanzio, Alessia Lamolinara, Jürgen Bukur, Anja Müller, Bernhard Hiebl, Hans-Jürgen Holzhausen & Barbara Seliger. (2013) HER-2/neu Mediates Oncogenic Transformation via Altered CREB Expression and Function. Molecular Cancer Research 11:11, pages 1462-1477.
Crossref
H. Pitman, B. A. Innes, S. C. Robson, J. N. Bulmer & G. E. Lash. (2013) Altered expression of interleukin-6, interleukin-8 and their receptors in decidua of women with sporadic miscarriage. Human Reproduction 28:8, pages 2075-2086.
Crossref
Christian V. Recktenwald, Sandra Leisz, André Steven, Kousaku Mimura, Anja Müller, Jens Wulfänger, Rolf Kiessling & Barbara Seliger. (2012) HER-2/neu-mediated Down-regulation of Biglycan Associated with Altered Growth Properties. Journal of Biological Chemistry 287:29, pages 24320-24329.
Crossref
Jianhui Zhu, Jintang He, Yashu Liu, Diane M. Simeone & David M. Lubman. (2012) Identification of Glycoprotein Markers for Pancreatic Cancer CD24 + CD44 + Stem-like Cells Using Nano-LC–MS/MS and Tissue Microarray . Journal of Proteome Research 11:4, pages 2272-2281.
Crossref
Jens Wulfänger, Heike Schneider, Peter Wild, Kristian Ikenberg, Monica Rodolfo, Licia Rivoltini, Stefanie Meyer, Dagmar Riemann & Barbara Seliger. (2012) Promoter methylation of aminopeptidase N/CD13 in malignant melanoma. Carcinogenesis 33:4, pages 781-790.
Crossref
Amy Lai, Abdi Ghaffari, Yunyuan Li & Aziz Ghahary. (2012) Microarray-based identification of aminopeptidase N target genes in keratinocyte conditioned medium-stimulated dermal fibroblasts. Journal of Cellular Biochemistry 113:3, pages 1061-1068.
Crossref
Jian-Jun Gao, Xia Xue, Zu-Hua Gao, Shu-Xiang Cui, Yan-Na Cheng, Wen-Fang Xu, Wei Tang & Xian-Jun Qu. (2011) LYP, a bestatin dimethylaminoethyl ester, inhibited cancer angiogenesis both in vitro and in vivo. Microvascular Research 82:2, pages 122-130.
Crossref
Jian-Jun Gao, Zu-Hua Gao, Cui-Rong Zhao, Yi Yuan, Shu-Xiang Cui, Xiao-Fan Zhang, Yan-Na Cheng, Wen-Fang Xu, Wei Tang & Xian-Jun Qu. (2010) LYP, a novel bestatin derivative, inhibits cell growth and suppresses APN/CD13 activity in human ovarian carcinoma cells more potently than bestatin. Investigational New Drugs 29:4, pages 574-582.
Crossref
Malin Wickström, Rolf Larsson, Peter Nygren & Joachim Gullbo. (2011) Aminopeptidase N (CD13) as a target for cancer chemotherapy. Cancer Science 102:3, pages 501-508.
Crossref
Paola Di Matteo, Gian Luigi Arrigoni, Luca Alberici, Angelo Corti, Corrado Gallo-Stampino, Catia Traversari, Claudio Doglioni & Gian-Paolo Rizzardi. (2011) Enhanced Expression of CD13 in Vessels of Inflammatory and Neoplastic Tissues. Journal of Histochemistry & Cytochemistry 59:1, pages 47-59.
Crossref
Amy Lai, Abdi Ghaffari & Aziz Ghahary. (2010) Inhibitory effect of anti-aminopeptidase N/CD13 antibodies on fibroblast migration. Molecular and Cellular Biochemistry 343:1-2, pages 191-199.
Crossref
Juergen Bukur, Dennis Loeffler, Chiara Massa, Lutz Mueller, Dagmar Riemann, Hans-Joachim Schmoll & Barbara Seliger. (2008) “Tumor immunology meets oncology IV”, 23rd and 24th May 2008 Martin Luther University Halle-Wittenberg, Halle, Germany. Cancer Immunology, Immunotherapy 59:6, pages 955-962.
Crossref
Xuejian Wang, Lei Zhang, Kanghui Yang, Cai Zhang, Jian Zhang, Hao Fang & Wenfang Xu. (2010) The Effect of Different Species Aminopeptidase N Structure on the Activity Screening of Aminopeptidase N Inhibitor. Biological & Pharmaceutical Bulletin 33:10, pages 1658-1665.
Crossref
Wendy Ann Peer, Fazeeda N. Hosein, Anindita Bandyopadhyay, Srinivas N. Makam, Marisa S. Otegui, Gil-Je Lee, Joshua J. Blakeslee, Yan Cheng, Boosaree Titapiwatanakun, Bahktiyor Yakubov, Bharat Bangari & Angus S. Murphy. (2009) Mutation of the Membrane-Associated M1 Protease APM1 Results in Distinct Embryonic and Seedling Developmental Defects in Arabidopsis     . The Plant Cell 21:6, pages 1693-1721.
Crossref
Paola Mina-Osorio. (2008) The moonlighting enzyme CD13: old and new functions to target. Trends in Molecular Medicine 14:8, pages 361-371.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.