Advanced search
Publication Cover
Molecular Membrane Biology Volume 22, 2005 - Issue 4
Journal homepage
1,470
Views
56
CrossRef citations to date
0
Altmetric
Original

Characterization of the human SLC2A11 (GLUT11) gene: alternative promoter usage, function, expression, and subcellular distribution of three isoforms, and lack of mouse orthologue

Andrea Scheepers Department of Pharmacology, German Institute of Human Nutrition, Potsdam-Rehbruecke, Germany
,
Stefan Schmidt Department of Pharmacology, German Institute of Human Nutrition, Potsdam-Rehbruecke, Germany
,
Andrei Manolescu Department of Physiology, University of Alberta, Edmonton, Canada
,
Chris I. Cheeseman Department of Physiology, University of Alberta, Edmonton, Canada
,
Andreas Bell Institute of Pharmacology and Toxicology, Medical Faculty, Technical University of Aachen, Germany
,
Claudia Zahn Department of Pharmacology, German Institute of Human Nutrition, Potsdam-Rehbruecke, Germany
,
Hans-Georg Joost Department of Pharmacology, German Institute of Human Nutrition, Potsdam-Rehbruecke, Germany
&
Dr Annette Schürmann Department of Pharmacology, German Institute of Human Nutrition, Potsdam-Rehbruecke, GermanyCorrespondence[email protected]
 show all
Pages 339-351 | Received 07 Feb 2005, Published online: 09 Jul 2009

Citations (56)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Thomas Amann & Claus Hellerbrand. (2009) GLUT1 as a therapeutic target in hepatocellular carcinoma. Expert Opinion on Therapeutic Targets 13:12, pages 1411-1427.
Read now
Andrei R. Manolescu, Robert Augustin, Kelle Moley & Chris Cheeseman. (2007) A highly conserved hydrophobic motif in the exofacial vestibule of fructose transporting SLC2A proteins acts as a critical determinant of their substrate selectivity. Molecular Membrane Biology 24:5-6, pages 455-463.
Read now

Articles from other publishers (54)

Abdelrahman Ismail & Marina Tanasova. (2022) Importance of GLUT Transporters in Disease Diagnosis and Treatment. International Journal of Molecular Sciences 23:15, pages 8698.
Crossref
De-Dong Li, Chetan V. Jawale, Chunsheng Zhou, Li Lin, Giraldina J. Trevejo-Nunez, Syed A. Rahman, Steven J. Mullet, Jishnu Das, Stacy G. Wendell, Greg M. Delgoffe, Michail S. Lionakis, Sarah L. Gaffen & Partha S. Biswas. (2022) Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity. Cell Host & Microbe 30:4, pages 530-544.e6.
Crossref
Anil Gupta. 2022. Understanding Insulin and Insulin Resistance. Understanding Insulin and Insulin Resistance 179 201 .
Ragnhild Inderberg Vestrum, Torunn Forberg, Birgit Luef, Ingrid Bakke, Per Winge, Yngvar Olsen & Olav Vadstein. (2021) Commensal and Opportunistic Bacteria Present in the Microbiota in Atlantic Cod (Gadus morhua) Larvae Differentially Alter the Hosts’ Innate Immune Responses. Microorganisms 10:1, pages 24.
Crossref
Aleksandra Sędzikowska & Leszek Szablewski. (2021) Human Glucose Transporters in Renal Glucose Homeostasis. International Journal of Molecular Sciences 22:24, pages 13522.
Crossref
O. Petteri Hirvonen, Heikki Kyröläinen, Maarit Lehti & Heikki Kainulainen. (2021) Randomized Trial: D-Glyceric Acid Activates Mitochondrial Metabolism in 50–60-Year-Old Healthy Humans. Frontiers in Aging 2.
Crossref
M. Annandale, L. J. Daniels, X. Li, J. P. H. Neale, A. H. L. Chau, H. A. Ambalawanar, S. L. James, P. Koutsifeli, L. M. D. Delbridge & K. M. Mellor. (2021) Fructose Metabolism and Cardiac Metabolic Stress. Frontiers in Pharmacology 12.
Crossref
Xiaotong Chen, Yunshuo Zhao, Yanfeng Gao, Yuanming Qi & Jiangfeng Du. (2021) GLUT1: a promising drug target for cancer treatment. Anti-Cancer Drugs 32:4, pages 345-364.
Crossref
Pedro Andrade, Małgorzata A. Gazda, Pedro M. Araújo, Sandra Afonso, Jacob. A. Rasmussen, Cristiana I. Marques, Ricardo J. Lopes, M. Thomas P. Gilbert. & Miguel Carneiro. (2021) Molecular parallelisms between pigmentation in the avian iris and the integument of ectothermic vertebrates. PLOS Genetics 17:2, pages e1009404.
Crossref
Guilherme Pegas Teixeira & Robson Xavier Faria. (2021) Influence of purinergic signaling on glucose transporters: A possible mechanism against insulin resistance?. European Journal of Pharmacology 892, pages 173743.
Crossref
Paweł Jan Stanirowski, Michał Lipa, Dorota Bomba-Opoń & Mirosław Wielgoś. 2021. 95 131 .
Tiannan Wang, Jing Wang, Xinge Hu, Xianju Huang & Guo-Xun Chen. (2020) Current understanding of glucose transporter 4 expression and functional mechanisms. World Journal of Biological Chemistry 11:3, pages 76-98.
Crossref
Geoffrey D. Holman. (2020) Structure, function and regulation of mammalian glucose transporters of the SLC2 family. Pflügers Archiv - European Journal of Physiology 472:9, pages 1155-1175.
Crossref
Constantin Berger & Daniela Zdzieblo. (2020) Glucose transporters in pancreatic islets. Pflügers Archiv - European Journal of Physiology 472:9, pages 1249-1272.
Crossref
Jean-Marc Jeckelmann & Bernhard Erni. (2020) Transporters of glucose and other carbohydrates in bacteria. Pflügers Archiv - European Journal of Physiology 472:9, pages 1129-1153.
Crossref
Cesar A. Martinez & Claudio Scafoglio. (2020) Heterogeneity of Glucose Transport in Lung Cancer. Biomolecules 10:6, pages 868.
Crossref
Sanaz Dastghaib, Abbas Afkhami, Pooneh Mokarram, Tayyebeh Madrakian & Mazaher Ahmadi. 2020. Smart Nanocontainers. Smart Nanocontainers 251 269 .
Ban Liu, Yuliang Wang, Yangyang Zhang & Biao Yan. (2019) Mechanisms of Protective Effects of SGLT2 Inhibitors in Cardiovascular Disease and Renal Dysfunction. Current Topics in Medicinal Chemistry 19:20, pages 1818-1849.
Crossref
Jessica I. Selig, D. Margriet Ouwens, Silja Raschke, G. Hege Thoresen, Jens W. Fischer, Artur Lichtenberg, Payam Akhyari & Mareike Barth. (2019) Impact of hyperinsulinemia and hyperglycemia on valvular interstitial cells – A link between aortic heart valve degeneration and type 2 diabetes. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1865:9, pages 2526-2537.
Crossref
Elizabeth A. Hausner, Susan A. Elmore & Xi Yang. (2019) Overview of the Components of Cardiac Metabolism. Drug Metabolism and Disposition 47:6, pages 673-688.
Crossref
Rafaela Salgado Ferreira, Jean-Luc Pons & Gilles Labesse. (2019) Insights into Substrate and Inhibitor Selectivity among Human GLUT Transporters through Comparative Modeling and Molecular Docking. ACS Omega 4:3, pages 4748-4760.
Crossref
Daniela Carreño, Néstor Corro, Verónica Torres-Estay, Loreto P. Véliz, Rodrigo Jaimovich, Pedro Cisternas, Ignacio F. San Francisco, Paula C. Sotomayor, Marina Tanasova, Nibaldo C. Inestrosa & Alejandro S. Godoy. (2018) Fructose and prostate cancer: toward an integrated view of cancer cell metabolism. Prostate Cancer and Prostatic Diseases 22:1, pages 49-58.
Crossref
Jie Zhang, Shan Jiang, Jin Wei, Kay-Pong Yip, Lei Wang, En Yin Lai & Ruisheng Liu. (2018) Glucose dilates renal afferent arterioles via glucose transporter-1. American Journal of Physiology-Renal Physiology 315:1, pages F123-F129.
Crossref
Julia S. Gauer, Sarka Tumova, Jonathan D. Lippiat, Asimina Kerimi & Gary Williamson. (2018) Differential patterns of inhibition of the sugar transporters GLUT2, GLUT5 and GLUT7 by flavonoids. Biochemical Pharmacology 152, pages 11-20.
Crossref
Paweł Jan Stanirowski, Dariusz Szukiewicz, Monika Pazura-Turowska, Włodzimierz Sawicki & Krzysztof Cendrowski. (2018) Placental Expression of Glucose Transporter Proteins in Pregnancies Complicated by Gestational and Pregestational Diabetes Mellitus. Canadian Journal of Diabetes 42:2, pages 209-217.
Crossref
Shawna L. McMillin, Denise L. Schmidt, Barbara B. Kahn & Carol A. Witczak. (2017) GLUT4 Is Not Necessary for Overload-Induced Glucose Uptake or Hypertrophic Growth in Mouse Skeletal Muscle. Diabetes 66:6, pages 1491-1500.
Crossref
Mary Shannon Byers, Christianna Howard & Xiaofei Wang. (2017) Avian and Mammalian Facilitative Glucose Transporters. Microarrays 6:2, pages 7.
Crossref
Leszek Szablewski. (2017) Glucose transporters in healthy heart and in cardiac disease. International Journal of Cardiology 230, pages 70-75.
Crossref
Sarah A. Oppelt, Wanming Zhang & Dean R. Tolan. (2017) Specific regions of the brain are capable of fructose metabolism. Brain Research 1657, pages 312-322.
Crossref
Christopher P. Kovach, Dolly Al Koborssy, Zhenbo Huang, Brandon M. Chelette, James M. Fadool & Debra A. Fadool. (2016) Mitochondrial Ultrastructure and Glucose Signaling Pathways Attributed to the Kv1.3 Ion Channel. Frontiers in Physiology 7.
Crossref
Archana M. Navale & Archana N. Paranjape. (2016) Glucose transporters: physiological and pathological roles. Biophysical Reviews 8:1, pages 5-9.
Crossref
Carly C. Barron, Philip J. Bilan, Theodoros Tsakiridis & Evangelia Tsiani. (2016) Facilitative glucose transporters: Implications for cancer detection, prognosis and treatment. Metabolism 65:2, pages 124-139.
Crossref
Dan Shao & Rong Tian. 2011. Comprehensive Physiology. Comprehensive Physiology 331 351 .
Bjørnar Hassel, Ahmed Elsais, Anne-Sofie Frøland, Erik Taubøll, Leif Gjerstad, Yi Quan, Raymond Dingledine & Frode Rise. (2015) Uptake and metabolism of fructose by rat neocortical cells in vivo and by isolated nerve terminals in vitro . Journal of Neurochemistry 133:4, pages 572-581.
Crossref
Andr?s Szarka & Tibor Balogh. (2015) In silico aided thoughts on mitochondrial vitamin C transport. Journal of Theoretical Biology 365, pages 181-189.
Crossref
Anthony M. Carter. (2012) Evolution of Placental Function in Mammals: The Molecular Basis of Gas and Nutrient Transfer, Hormone Secretion, and Immune Responses. Physiological Reviews 92:4, pages 1543-1576.
Crossref
Samuel K. McBrayer, Javelin C. Cheng, Seema Singhal, Nancy L. Krett, Steven T. Rosen & Mala Shanmugam. (2012) Multiple myeloma exhibits novel dependence on GLUT4, GLUT8, and GLUT11: implications for glucose transporter-directed therapy. Blood 119:20, pages 4686-4697.
Crossref
Karin Reinicke, Paula Sotomayor, Pedro Cisterna, Carolina Delgado, Francisco Nualart & Alejandro Godoy. (2012) Cellular distribution of Glut-1 and Glut-5 in benign and malignant human prostate tissue. Journal of Cellular Biochemistry 113:2, pages 553-562.
Crossref
Kimberley M. Mellor, James R. Bell, Igor R. Wendt, Amy J. Davidoff, Rebecca H. Ritchie & Lea M. D. Delbridge. (2011) Fructose Modulates Cardiomyocyte Excitation-Contraction Coupling and Ca2+ Handling In Vitro. PLoS ONE 6:9, pages e25204.
Crossref
Midori Edamatsu, Yasuhiro Kondo & Motonori Ando. (2011) Multiple expression of glucose transporters in the lateral wall of the cochlear duct studied by quantitative real-time PCR assay. Neuroscience Letters 490:1, pages 72-77.
Crossref
Kristin P. Bibee, Nicholas P. Illsley & Kelle H. Moley. (2011) Asymmetric Syncytial Expression of GLUT9 Splice Variants in Human Term Placenta and Alterations in Diabetic Pregnancies. Reproductive Sciences 18:1, pages 20-27.
Crossref
Kimberley M. MellorRebecca H. RitchieAmy J. DavidoffLea M.D. Delbridge. (2010) Elevated dietary sugar and the heart: experimental models and myocardial remodeling. Canadian Journal of Physiology and Pharmacology 88:5, pages 525-540.
Crossref
Bernard Thorens & Mike Mueckler. (2010) Glucose transporters in the 21st Century. American Journal of Physiology-Endocrinology and Metabolism 298:2, pages E141-E145.
Crossref
Moisés Blanco Calvo, Angélica Figueroa, Enrique Grande Pulido, Rosario García Campelo & Luís Antón Aparicio. (2010) Potential Role of Sugar Transporters in Cancer and Their Relationship with Anticancer Therapy. International Journal of Endocrinology 2010, pages 1-14.
Crossref
Chris I. Cheeseman. 2010. Epithelial Transport Physiology. Epithelial Transport Physiology 323 352 .
Robert Augustin. (2010) The protein family of glucose transport facilitators: It's not only about glucose after all. IUBMB Life, pages NA-NA.
Crossref
J. R. Aschenbach, K. Steglich, G. Gäbel & K. U. Honscha. (2009) Expression of mRNA for glucose transport proteins in jejunum, liver, kidney and skeletal muscle of pigs. Journal of Physiology and Biochemistry 65:3, pages 251-266.
Crossref
Y. Izumi & C.F. Zorumski. (2009) Glial–neuronal interactions underlying fructose utilization in rat hippocampal slices. Neuroscience 161:3, pages 847-854.
Crossref
Amparo Romero, Olga Gomez, Jose Terrado & Jose E. Mesonero. (2009) Expression of GLUT8 in mouse intestine: Identification of alternative spliced variants. Journal of Cellular Biochemistry 106:6, pages 1068-1078.
Crossref
Angela Döring, Christian Gieger, Divya Mehta, Henning Gohlke, Holger Prokisch, Stefan Coassin, Guido Fischer, Kathleen Henke, Norman Klopp, Florian Kronenberg, Bernhard Paulweber, Arne Pfeufer, Dieter Rosskopf, Henry Völzke, Thomas Illig, Thomas Meitinger, H-Erich Wichmann & Christa Meisinger. (2008) SLC2A9 influences uric acid concentrations with pronounced sex-specific effects. Nature Genetics 40:4, pages 430-436.
Crossref
Andrei R. Manolescu, Kate Witkowska, Adam Kinnaird, Tara Cessford & Chris Cheeseman. (2007) Facilitated Hexose Transporters: New Perspectives on Form and Function. Physiology 22:4, pages 234-240.
Crossref
Michael Gaster. (2008) Fibre Type Dependent Expression of Glucose Transporters in Human Skeletal Muscles. APMIS 115, pages 1-48.
Crossref
Michael Gaster. (2007) Fibre Type Dependent Expression of Glucose Transporters in Human Skeletal Muscles. APMIS 115:s121, pages 1-48.
Crossref
Chithra KeembiyehettyRobert AugustinMary O. CarayannopoulosSarah SteerAndrei Manolescu, Chris I. Cheeseman & Kelle H. Moley. (2006) Mouse Glucose Transporter 9 Splice Variants Are Expressed in Adult Liver and Kidney and Are Up-Regulated in Diabetes. Molecular Endocrinology 20:3, pages 686-697.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.