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Original Articles

Studies on cytotoxic constituents from the skin of the toad Bufo bufo gargarizans

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Pages 793-800 | Received 02 Feb 2010, Accepted 28 Jun 2010, Published online: 13 Sep 2010

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Lingjie Meng, Sanhua Li, Qinghong Kong, Mei Wang, Xiaoke Zhang, Xinting Zhu, Wei Yu, Nian Jiang, Zeli Chun, Nian Li & Yun Liu. (2021) Two new 19-hydroxy bufadienolides with cytotoxic activity from the skins of Bufo melanosticus. Natural Product Research 35:23, pages 4894-4900.
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Ying-Hui Dai, An-Dong Wang, Yu-Lin Chen, Ming-Yu Xia, Xin-Yi Shao, Dong-Chun Liu & Dong Wang. (2018) A new indole alkaloid from the traditional Chinese medicine Chansu. Journal of Asian Natural Products Research 20:6, pages 581-585.
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Xiu-Lan Xin, Pei-Pei Dong, Xiao-Hong Sun, Sa Deng, Ning Zhang, Chao Wang, Xiao-Kui Huo, Ye Li, Rong Lan, Liang Chen & Guang-Jun Fan. (2016) Identification of the hydroxylated derivatives of bufalin: phase I metabolites in rats. Journal of Asian Natural Products Research 18:3, pages 239-247.
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Fu-Kai Wu, Ying-Kun Qiu, Hu-Yi Zhao, Zhen Wu, Fa-Mei Li, Yong-Tao Jiang & Ji-Yong Chen. (2011) Cytotoxic constituents from the skin of the toad Bufo bufo gargarizans . Journal of Asian Natural Products Research 13:2, pages 111-116.
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Li-Wen Zhu, Bao-Ying Xie, Shun-Zhi Liu, Yi-Hong Wu, Guo-Gang Zhang & Ying-Kun Qiu. (2023) Development of an On-Line Two-dimensional Normal Phase Liquid Chromatography System for Analysis of Weakly Polar Samples. Chromatographia 86:4, pages 285-293.
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Candelario Rodriguez, Roberto Ibáñez, Luis Mojica, Michelle Ng, Carmenza Spadafora, Armando A. Durant-Archibold & Marcelino Gutiérrez. (2021) Bufadienolides from the Skin Secretions of the Neotropical Toad Rhinella alata (Anura: Bufonidae): Antiprotozoal Activity against Trypanosoma cruzi. Molecules 26:14, pages 4217.
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Shinsuke Shimizu, Koichi Hagiwara, Hiroaki Itoh & Masayuki Inoue. (2020) Unified Total Synthesis of Five Bufadienolides. Organic Letters 22:21, pages 8652-8657.
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Takato Inoue, Ryu Nakata, Alan H. Savitzky, Naoko Yoshinaga, Akira Mori & Naoki Mori. (2020) Variation in Bufadienolide Composition of Parotoid Gland Secretion From Three Taxa of Japanese Toads. Journal of Chemical Ecology 46:10, pages 997-1009.
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Xiang Zhan, Huan Wu, Hong Wu, Rong Wang, Chuan Luo, Bo Gao, Zhiwu Chen & Qinglin Li. (2020) Metabolites from Bufo gargarizans (Cantor, 1842): A review of traditional uses, pharmacological activity, toxicity and quality control. Journal of Ethnopharmacology 246, pages 112178.
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Lingjie Meng, Nian Jiang, Changyan Yu, Sanhua Li, Zeli Chun, Xinting Zhu, Changwei Song, Yi Xiao, Jing Hui, Ying Qin & Yun Liu. (2019) Bufadienolides from the skins of Bufo melanosticus and their cytotoxic activity. Phytochemistry Letters 31, pages 73-77.
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Wen-Long Wei, Jin-Jun Hou, Xia Wang, Yang Yu, Hao-Jv Li, Zhen-Wei Li, Zi-Jin Feng, Hua Qu, Wan-Ying Wu & De-An Guo. (2019) Venenum bufonis: An overview of its traditional use, natural product chemistry, pharmacology, pharmacokinetics and toxicology. Journal of Ethnopharmacology 237, pages 215-235.
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Zheng Wang, Ting-Ting Xie, Xia Yan, Shi Xue, Jing-Wei Chen, Zhen Wu & Ying-Kun Qiu. (2018) Gradual Gradient Two-Dimensional Preparative Liquid Chromatography System for Preparative Separation of Complex Natural Products. Chromatographia 82:2, pages 543-552.
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Hui Liu, Si-Yu Chen, Jia-Ying Guo, Pei Su, Ying-Kun Qiu, Cai-Huan Ke & Dan-Qing Feng. (2018) Effective natural antifouling compounds from the plant Nerium oleander and testing. International Biodeterioration & Biodegradation 127, pages 170-177.
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Syeda H. Afroze, Jenna Sloan, Grace-Ann C. Osuji, Nathan Drever, Kimberly Pilkinton, David C. Zawieja, Thomas J. Kuehl & M. Nasir Uddin. (2016) Cinobufotalin impedes Sw.71 cytotrophoblast cell line function via cell cycle arrest and apoptotic signaling. Molecular and Cellular Biochemistry 422:1-2, pages 189-196.
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Herbert Budzikiewicz. 2015. Progress in the Chemistry of Organic Natural Products 100. Progress in the Chemistry of Organic Natural Products 100 77 221 .
Xiaolong Li, Yanfang Liu, Aijin Shen, Chaoran Wang, Jingyu Yan, Weijie Zhao & Xinmiao Liang. (2014) Efficient purification of active bufadienolides by a class separation method based on hydrophilic solid-phase extraction and reversed-phase high performance liquid chromatography. Journal of Pharmaceutical and Biomedical Analysis 97, pages 54-64.
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Xiaolong Li, Zhimou Guo, Chaoran Wang, Aijin Shen, Yanfang Liu, Xiuli Zhang, Weijie Zhao & Xinmiao Liang. (2014) Purification of bufadienolides from the skin of Bufo bufo gargarizans Cantor with positively charged C18 column. Journal of Pharmaceutical and Biomedical Analysis 92, pages 105-113.
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Ying-Kun Qiu, Xia Yan, Mei-Juan Fang, Lin Chen, Zhen Wu & Yu-Fen Zhao. (2014) Two-dimensional countercurrent chromatography × high performance liquid chromatography for preparative isolation of toad venom. Journal of Chromatography A 1331, pages 80-89.
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Z Sun, X Cao, M-M Jiang, Y Qiu, H Zhou, L Chen, B Qin, H Wu, F Jiang, J Chen, J Liu, Y Dai, H-F Chen, Q-Y Hu, Z Wu, J-Z Zeng, X-S Yao & X-K Zhang. (2011) Inhibition of β-catenin signaling by nongenomic action of orphan nuclear receptor Nur77. Oncogene 31:21, pages 2653-2667.
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