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Journal of Asian Natural Products Research Volume 13, 2011 - Issue 9
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Original Articles

Two new casbane diterpenoids from the roots of Euphorbia pekinensis

Feng-Guang Shao School of Traditional Chinese Materia Medica 49#, Shenyang Pharmaceutical University, Shenyang, 110016, China; School of Pharmacy, Inner Mongolia Medical College, Hohhot, 010110, China
,
Ren Bu School of Pharmacy, Inner Mongolia Medical College, Hohhot, 010110, China
,
Cui Zhang School of Traditional Chinese Materia Medica 49#, Shenyang Pharmaceutical University, Shenyang, 110016, China
,
Chao-Jun Chen School of Pharmacy, Inner Mongolia Medical College, Hohhot, 010110, China
,
Jian Huang School of Traditional Chinese Materia Medica 49#, Shenyang Pharmaceutical University, Shenyang, 110016, China; Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, China
&
Jin-Hui Wang School of Traditional Chinese Materia Medica 49#, Shenyang Pharmaceutical University, Shenyang, 110016, China; School of Pharmacy, Inner Mongolia Medical College, Hohhot, 010110, China; Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, China; School of Pharmacy, Shihezi University, Shihezi, 832002, ChinaCorrespondence[email protected]
Pages 805-810 | Received 02 Apr 2011, Accepted 10 Jun 2011, Published online: 10 Aug 2011

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Zhenzhen Liu, Yan Zeng & Pengyi Hou. (2018) Metabolomic evaluation of Euphorbia pekinensis induced nephrotoxicity in rats. Pharmaceutical Biology 56:1, pages 145-153.
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Xiao-Xue Liu, Lei Shang, Chao Huang, Xue-Song Feng, Wen Li, Yi Sha, Jian Huang & Jin-Hui Wang. (2016) Four new diterpenoids isolated from the Euphorbia rapulum. Journal of Asian Natural Products Research 18:9, pages 823-830.
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Fu-Hu Fang, Wen-Hai Li, Zheng-Zhi Han, Wen-Jun Huang, Dong-Xu Li, Sha Zhao, Min-Hao Tang & Cheng-Shan Yuan. (2015) Terpenoids from Euphorbia pekinensis. Journal of Asian Natural Products Research 17:12, pages 1213-1219.
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Kuilong Wang, Hongli Yu, Hao Wu, Xinzhi Wang, Yaozong Pan, Yeqing Chen, Liping Liu, Yangping Jin & Chenchao Zhang. (2015) A new casbane diterpene from Euphorbia pekinensis. Natural Product Research 29:15, pages 1456-1460.
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Articles from other publishers (22)

Christian Bailly. (2023) Yuexiandajisu diterpenoids from Euphorbia ebracteolata Hayata (Langdu roots): An overview. Phytochemistry 213, pages 113784.
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Shi-Peng Guan, Ying Yang, Mao Sun, Min Cai, Xue-Xue Pu, Jian-Yi Huang, Ping Yi, Lin Liu, Ming-Rui Yuan, Yuan-Yuan Cheng & Ying-Tong Di. (2023) Euphpepluone S, a new lathyrane diterpenoid with anti-inflammatory activity from Euphorbia peplus L.. Phytochemistry Letters 55, pages 61-66.
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Smail Amtaghri, Mourad Akdad, Miloudia Slaoui & Mohamed Eddouks. (2022) Traditional Uses, Pharmacological, and Phytochemical Studies of Euphorbia : A Review . Current Topics in Medicinal Chemistry 22:19, pages 1553-1570.
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Ana Laura V. Alves, Luciane S. da Silva, Camila A. Faleiros, Viviane A. O. Silva & Rui M. Reis. (2022) The Role of Ingenane Diterpenes in Cancer Therapy: From Bioactive Secondary Compounds to Small Molecules. Natural Product Communications 17:7, pages 1934578X2211056.
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Wei-ni Qin, Kai-cheng Zhang, Ting Geng, Fang-fang Cheng, Pei-dong Chen, Wei-feng Yao, Li Zhang & Yu-dan Cao. (2021) The toxicity mechanism of toxic compounds from Euphorbiae pekinensis Radix on zebrafish embryos. Biomedicine & Pharmacotherapy 138, pages 111521.
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Lidia A. Maslovskaya, Andrei I. Savchenko, Elizabeth H. Krenske, Sharon Chow, Victoria A. Gordon, Paul W. Reddell, Carly J. Pierce, Peter G. Parsons, Glen M. Boyle & Craig M. Williams. (2020) EBC‐342: A Novel Tetrahydrofuran Moiety Containing Casbane from the Australian Rainforest. European Journal of Organic Chemistry 2020:8, pages 1042-1045.
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Lidiya A. Maslovskaya, Andrei I. Savchenko, Carly J. Pierce, Glen M. Boyle, Victoria A. Gordon, Paul W. Reddell, Peter G. Parsons & Craig M. Williams. (2019) New Casbanes and the First trans -Cyclopropane seco -Casbane from the Australian Rainforest Plant Croton insularis . Chemistry - A European Journal 25:6, pages 1525-1534.
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Hongli Yu, Lian Liu, Kuilong Wang, Hao Wu, Wei Wang, Xingde Zhang, Guojing Cui, Xiaobing Cui & Jianyu Huang. (2018) Upregulation of aquaporin 3 expression by diterpenoids in Euphorbia pekinensis is associated with activation of the NF-κB signaling pathway in the co-culture system of HT-29 and RAW 264.7 cells. Biochimie 144, pages 153-159.
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Xiaoying Cao, Fangzhou Zhang, Bo Yuan, Laisheng Meng, Xuqin Yang & Jihong Jiang. (2017) De novo transcriptome sequencing and analysis of Euphorbia pekinensis Rupr. and identification of genes involved in diterpenoid biosynthesis. Plant Gene 12, pages 33-42.
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Lu Fan, Qingling Xiao, Yanyan Chen, Gang Chen, Jinao Duan & Weiwei Tao. (2017) Pekinenin E Inhibits the Growth of Hepatocellular Carcinoma by Promoting Endoplasmic Reticulum Stress Mediated Cell Death. Frontiers in Pharmacology 8.
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Kuilong Wang, Lian Liu, Jianyu Huang, Hongli Yu, Hao Wu, Yu Duan, Xiaobing Cui, Xingde Zhang, Liping Liu & Wei Wang. (2017) Laxative Effects of Total Diterpenoids Extracted from the Roots of Euphorbia pekinensis Are Attributable to Alterations of Aquaporins in the Colon. Molecules 22:3, pages 465.
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Lidiya A. Maslovskaya, Andrei I. Savchenko, Victoria A. Gordon, Paul W. Reddell, Carly J. Pierce, Peter G. Parsons & Craig M. Williams. (2017) The First Casbane Hydroperoxides EBC-304 and EBC-320 from the Australian Rainforest. Chemistry - A European Journal 23:3, pages 537-540.
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Timothy J. Vanden Berg, David M. Pinkerton & Craig M. Williams. (2017) 7-Step total synthesis of (+)-EBC-329: Photoisomerisation reveals new seco-casbane family member. Organic & Biomolecular Chemistry 15:34, pages 7102-7105.
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Rui-Ying Tian, Yan Lu & Dao-Feng Chen. (2016) Four New Diterpenoids from the Roots of Euphorbia pekinensis . Chemistry & Biodiversity 13:10, pages 1404-1409.
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Yudan Cao, Fangfang Cheng, Weifeng Yao, Beihua Bao, Kaicheng Zhang, Li Zhang & Anwei Ding. (2016) Toxicity of Pekinenin C from Euphorbia Pekinensis Radix on Rat Small Intestinal Crypt Epithelial Cell and Its Apoptotic Mechanism. International Journal of Molecular Sciences 17:6, pages 850.
Crossref
Jie Gao, Qi-Bin Chen, Yong-Qiang Liu, Xue-Lei Xin, Ablimiti Yili & Haji Akber Aisa. (2016) Diterpenoid constituents of Euphorbia macrorrhiza. Phytochemistry 122, pages 246-253.
Crossref
Chun-Shuai Huang, Shi-Hong Luo, Yao-Lan Li, Chun-Huan Li, Juan Hua, Yan Liu, Shu-Xi Jing, Ying Wang, Min-Jie Yang & Sheng-Hong Li. (2014) Antifeedant and Antiviral Diterpenoids from the Fresh Roots of Euphorbia jolkinii. Natural Products and Bioprospecting 4:2, pages 91-100.
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María Jesús Durán-Peña, José Manuel Botubol Ares, Isidro G. Collado & Rosario Hernández-Galán. (2014) Biologically active diterpenes containing a gem-dimethylcyclopropane subunit: an intriguing source of PKC modulators. Nat. Prod. Rep. 31:7, pages 940-952.
Crossref
Wei-Wei Tao, Jin-Ao Duan, Yu-Ping Tang, Nian-Yun Yang, Jian-Ping Li & Ye-Fei Qian. (2013) Casbane diterpenoids from the roots of Euphorbia pekinensis. Phytochemistry 94, pages 249-253.
Crossref
Pengyi Hou, Yan Zeng, Bingjie Ma, Kaishun Bi & Xiaohui Chen. (2013) A new cytotoxic cembrane diterpene from the roots of Euphorbia pekinensis Rupr. Fitoterapia 90, pages 10-13.
Crossref
Pengyi Hou, Yan Zeng, Bingjie Ma, Xiaofan Wang, Zhenzhen Liu, Lu Li, Kankan Qu, Kaishun Bi & Xiaohui Chen. (2013) A fast, sensitive, and high-throughput method for the simultaneous quantitation of three ellagitannins from Euphorbiae pekinensis Radix in rat plasma by ultra-HPLC-MS/MS . Journal of Separation Science 36:15, pages 2544-2551.
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Jian Yin, Min Zhao, Minshan Ma, Yuping Xu, Zheng Xiang, Yuepiao Cai, Jianyong Dong, Xinxiang Lei, Kexin Huang & Pengcheng Yan. (2013) New Casbane Diterpenoids from a South China Sea Soft Coral, Sinularia sp.. Marine Drugs 11:12, pages 455-465.
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