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Original Articles

Garcinia mangostana: a source of potential anti-cancer lead compounds against CEM-SS cell line

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Pages 475-479 | Received 08 Oct 2007, Accepted 08 Jan 2008, Published online: 27 Jul 2010

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Eun-Bin KwonDong-Oh MoonEun Sol OhYu Na SongJi-Yoon ParkHyung Won RyuDoo-Young KimYoung-Won ChinHyun-Sun LeeSu Ui LeeMun-Ock Kim. (2023) Garcinia mangostana Suppresses Triacylglycerol Synthesis in Hepatocytes and Enterocytes . Journal of Medicinal Food 26:10, pages 732-738.
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Manzar Alam, Summya Rashid, Kisa Fatima, Mohd Adnan, Alaa Shafie, Mohammad Salman Akhtar, A.H. Ganie, Sayed M. Eldin, Asimul Islam, Ilyas Khan & Md. Imtaiyaz Hassan. (2023) Biochemical features and therapeutic potential of α-Mangostin: Mechanism of action, medicinal values, and health benefits. Biomedicine & Pharmacotherapy 163, pages 114710.
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Lindsay S. Kalick, Hamaad A. Khan, Erica Maung, Yasmany Baez, Alexa N. Atkinson, Carly E. Wallace, Faith Day, Blake E. Delgadillo, Arijit Mondal, Ramida Watanapokasin, Sandra M. Barbalho & Anupam Bishayee. (2023) Mangosteen for malignancy prevention and intervention: Current evidence, molecular mechanisms, and future perspectives. Pharmacological Research 188, pages 106630.
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Roghayeh Rashidi, Fatemeh Forouzanfar, Mohammad Soukhtanloo, Shirin Ghasemian & Seyed Hadi Mousavi. (2022) Cytotoxic Effects of Garcinia mangostana Pericarp Extract on Cancer Cell Lines . Current Drug Discovery Technologies 19:2.
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Mirielle C. Nauman & Jeremy J. Johnson. (2022) The purple mangosteen (Garcinia mangostana): Defining the anticancer potential of selected xanthones. Pharmacological Research 175, pages 106032.
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Aihong Yang, Qiao Yu, Hui Ju, Lulu Song, Xiaodi Kou & Rui Shen. (2020) Design, Synthesis and Biological Evaluation of Xanthone Derivatives for Possible Treatment of Alzheimer's Disease Based on Multi‐Target Strategy. Chemistry & Biodiversity 17:10.
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Thao T.D. Tran & Phuong H.L. Tran. (2020) Lead Compounds in the Context of Extracellular Vesicle Research. Pharmaceutics 12:8, pages 716.
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Minh H. Nguyen, Dat T. Nguyen & Phuong T.M. Nguyen. (2020) Apoptosis induction by α-mangostin-loaded nanoparticles in human cervical carcinoma cells. Zeitschrift für Naturforschung C 75:5-6, pages 145-151.
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Nguyen Thi Mai Phuong, Ngo Van Quang, Ta Thu Mai, Nguyen Vu Anh, Chutima Kuhakarn, Vichai Reutrakul & Albert Bolhuis. (2017) Antibiofilm activity of α-mangostin extracted from Garcinia mangostana L. against Staphylococcus aureus. Asian Pacific Journal of Tropical Medicine 10:12, pages 1154-1160.
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Xiaohong Yang, Shengnan Wang, Ying Ouyang, Yaling Tu, Anmin Liu, Yinghong Tian, Mingliang He & Rongbiao Pi. (2016) Garcinone D, a natural xanthone promotes C17.2 neural stem cell proliferation: Possible involvement of STAT3/Cyclin D1 pathway and Nrf2/HO-1 pathway. Neuroscience Letters 626, pages 6-12.
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Hélio M. T. Albuquerque, Clementina M. M. Santos, José A. S. Cavaleiro & Artur M. S. Silva. (2015) ( E )‐2‐(4‐Arylbut‐1‐en‐3‐yn‐1‐yl)chromones as Synthons for the Synthesis of Xanthone‐1,2,3‐triazole Dyads . European Journal of Organic Chemistry 2015:21, pages 4732-4743.
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Phuong Thi Mai Nguyen, Megan L. Falsetta, Geelsu Hwang, Mireya Gonzalez-Begne & Hyun Koo. (2014) α-Mangostin Disrupts the Development of Streptococcus mutans Biofilms and Facilitates Its Mechanical Removal. PLoS ONE 9:10, pages e111312.
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Irene See, Gwendoline Ee, Soek Teh, Arifah Kadir & Shaari Daud. (2014) Two New Chemical Constituents from the Stem Bark of Garcinia mangostana. Molecules 19:6, pages 7308-7316.
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Sakina M. Petiwala, Gongbo Li, Atulkumar Ramaiya, Anoop Kumar, Ravinder K. Gill, Seema Saksena & Jeremy J. Johnson. (2014) Pharmacokinetic characterization of mangosteen (Garcinia mangostana) fruit extract standardized to α-mangostin in C57BL/6 mice. Nutrition Research 34:4, pages 336-345.
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Jing J. Wang, Barbara J.S. Sanderson & Wei Zhang. (2011) Cytotoxic effect of xanthones from pericarp of the tropical fruit mangosteen (Garcinia mangostana Linn.) on human melanoma cells. Food and Chemical Toxicology 49:9, pages 2385-2391.
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M. Hemshekhar, K. Sunitha, M. Sebastin Santhosh, S. Devaraja, K. Kemparaju, B. S. Vishwanath, S. R. Niranjana & K. S. Girish. (2011) An overview on genus garcinia: phytochemical and therapeutical aspects. Phytochemistry Reviews 10:3, pages 325-351.
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Phuong T. M. NguyenRobert E. Marquis. (2011) Antimicrobial actions of α-mangostin against oral streptococci. Canadian Journal of Microbiology 57:3, pages 217-225.
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Ramida Watanapokasin, Faongchat Jarinthanan, Alan Jerusalmi, Sunit Suksamrarn, Yukio Nakamura, Supawadee Sukseree, Wanlaya Uthaisang-Tanethpongtamb, Piniti Ratananukul & Takeshi Sano. (2010) Potential of Xanthones from Tropical Fruit Mangosteen as Anti-cancer Agents: Caspase-Dependent Apoptosis Induction In Vitro and in Mice. Applied Biochemistry and Biotechnology 162:4, pages 1080-1094.
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Clementina M.M. Santos, Marisa Freitas, Daniela Ribeiro, Ana Gomes, Artur M.S. Silva, José A.S. Cavaleiro & Eduarda Fernandes. (2010) 2,3-Diarylxanthones as strong scavengers of reactive oxygen and nitrogen species: A structure–activity relationship study. Bioorganic & Medicinal Chemistry 18:18, pages 6776-6784.
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