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Original Articles

Caffeine Use in Sports, Pharmacokinetics in Man, and Cellular Mechanisms of Action

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Pages 535-562 | Published online: 18 Jan 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (27)

Alisson H. Marinho, Jaqueline S. Gonçalves, Palloma K. Araújo, Adriano E. Lima-Silva, Thays Ataide-Silva & Gustavo G. de Araujo. (2023) Effects of creatine and caffeine ingestion in combination on exercise performance: A systematic review. Critical Reviews in Food Science and Nutrition 63:20, pages 4785-4798.
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Jaime González-García, Millán Aguilar-Navarro, Verónica Giráldez-Costas & Blanca Romero-Moraleda. (2023) Time Course of Jump Recovery and Performance After Velocity-Based Priming and Concurrent Caffeine Intake. Research Quarterly for Exercise and Sport 94:3, pages 655-667.
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Houda Bougrine, Moncef Cherif, Hamdi Chtourou & Nizar Souissi. (2022) Can caffeine supplementation reverse the impact of time of day on cognitive and short-term high intensity performances in young female handball players?. Chronobiology International 39:8, pages 1144-1155.
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Alisson Henrique Marinho, João Paulo Lopes-Silva, Gislaine Cristina-Souza, Filipe Antônio de Barros Sousa, Thays Ataide-Silva, Adriano Eduardo Lima-Silva, Gustavo Gomes de Araujo & Marcos David Silva‑Cavalcante. (2022) Effects of caffeine ingestion on cardiopulmonary responses during a maximal graded exercise test: a systematic review with meta-analysis and meta-regression. Critical Reviews in Food Science and Nutrition 0:0, pages 1-13.
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Beatriz Redondo, Jesús Vera, George-Alex Koulieris, Rubén Molina-Romero & Raimundo Jiménez. (2022) Short-term effects of caffeine intake on binocular accommodative facility: a quantitative and qualitative analysis. Clinical and Experimental Optometry 105:5, pages 534-538.
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Vincent Grémain, Lucie Chevillard, Elodie Saussereau, Guillaume Schnell & Bruno Mégarbane. (2021) Massive suicidal ingestion of caffeine: a case report with investigation of the cardiovascular effect/concentration relationships. Clinical Toxicology 59:10, pages 937-941.
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Aleksandra Filip-Stachnik, Michal Wilk, Michal Krzysztofik, Ewelina Lulińska, James J. Tufano, Adam Zajac, Petr Stastny & Juan Del Coso. (2021) The effects of different doses of caffeine on maximal strength and strength‐endurance in women habituated to caffeine. Journal of the International Society of Sports Nutrition 18:1.
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Nanci S. Guest, Trisha A. VanDusseldorp, Michael T. Nelson, Jozo Grgic, Brad J. Schoenfeld, Nathaniel D. M. Jenkins, Shawn M. Arent, Jose Antonio, Jeffrey R. Stout, Eric T. Trexler, Abbie E. Smith-Ryan, Erica R. Goldstein, Douglas S. Kalman & Bill I. Campbell. (2021) International society of sports nutrition position stand: caffeine and exercise performance. Journal of the International Society of Sports Nutrition 18:1.
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Juan José Salinero, Beatriz Lara & Juan Del Coso. (2019) Effects of acute ingestion of caffeine on team sports performance: a systematic review and meta-analysis. Research in Sports Medicine 27:2, pages 238-256.
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Vikash K. Sonu, Imocha Rajkumar, Kaushik Bhattacharjee, S.R. Joshi & Sivaprasad Mitra. (2019) Interaction of caffeine and sulfadiazine with lysozyme adsorbed at colloidal metal nanoparticle interface: influence on drug transport ability and antibacterial activity. Journal of Biomolecular Structure and Dynamics 37:2, pages 321-335.
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Krzysztof Durkalec-Michalski, Paulina M. Nowaczyk, Natalia Główka & Aleksandra Grygiel. (2019) Dose-dependent effect of caffeine supplementation on judo-specific performance and training activity: a randomized placebo-controlled crossover trial. Journal of the International Society of Sports Nutrition 16:1.
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M. K. Ranchordas, H. Pratt, M. Parsons, A. Parry, C. Boyd & A. Lynn. (2019) Effect of caffeinated gum on a battery of rugby-specific tests in trained university-standard male rugby union players. Journal of the International Society of Sports Nutrition 16:1.
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Michal Wilk, Michal Krzysztofik, Adam Maszczyk, Jakub Chycki & Adam Zajac. (2019) The acute effects of caffeine intake on time under tension and power generated during the bench press movement. Journal of the International Society of Sports Nutrition 16:1.
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Chanaka N. Kahathuduwa, Tharaka L. Dassanayake, A. M. Tissa Amarakoon & Vajira S. Weerasinghe. (2017) Acute effects of theanine, caffeine and theanine–caffeine combination on attention. Nutritional Neuroscience 20:6, pages 369-377.
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Francisco Javier Diaz-Lara, Juan Del Coso, Jose Manuel García, Luis J. Portillo, Francisco Areces & Javier Abián-Vicén. (2016) Caffeine improves muscular performance in elite Brazilian Jiu-jitsu athletes. European Journal of Sport Science 16:8, pages 1079-1086.
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Mark Glaister, Daniel Muniz-Pumares, Stephen D. Patterson, Paul Foley & Gillian McInnes. (2015) Caffeine supplementation and peak anaerobic power output. European Journal of Sport Science 15:5, pages 400-406.
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Pablo Abian, Juan Del Coso, Juan José Salinero, Cesar Gallo-Salazar, Francisco Areces, Diana Ruiz-Vicente, Beatriz Lara, Lidon Soriano, Victor Muñoz & Javier Abian-Vicen. (2015) The ingestion of a caffeinated energy drink improves jump performance and activity patterns in elite badminton players. Journal of Sports Sciences 33:10, pages 1042-1050.
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Fahad Ali, Hiba Rehman, Zaruhi Babayan, Dwight Stapleton & Divya-Devi Joshi. (2015) Energy drinks and their adverse health effects: A systematic review of the current evidence. Postgraduate Medicine 127:3, pages 308-322.
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Juan Del Coso, Juan José Salinero, Cristina González-Millán, Javier Abián-Vicén & Benito Pérez-González. (2012) Dose response effects of a caffeine-containing energy drink on muscle performance: a repeated measures design. Journal of the International Society of Sports Nutrition 9:1.
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Frederico SC Franco, Neuza MB Costa, Susana A Ferreira, Miguel A Carneiro-Junior & Antônio J Natali. (2011) The effects of a high dosage of creatine and caffeine supplementation on the lean body mass composition of rats submitted to vertical jumping training. Journal of the International Society of Sports Nutrition 8:1.
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Erin Duchan, Neil D. Patel & Cynthia Feucht. (2010) Energy Drinks: A Review of Use and Safety for Athletes. The Physician and Sportsmedicine 38:2, pages 171-179.
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SimonP. Roberts, KeithA. Stokes, Grant Trewartha, Jenny Doyle, Patrick Hogben & Dylan Thompson. (2010) Effects of carbohydrate and caffeine ingestion on performance during a rugby union simulation protocol. Journal of Sports Sciences 28:8, pages 833-842.
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Erica R Goldstein, Tim Ziegenfuss, Doug Kalman, Richard Kreider, Bill Campbell, Colin Wilborn, Lem Taylor, Darryn Willoughby, Jeff Stout, B Sue Graves, Robert Wildman, John L Ivy, Marie Spano, Abbie E Smith & Jose Antonio. (2010) International society of sports nutrition position stand: caffeine and performance. Journal of the International Society of Sports Nutrition 7:1.
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Abbie E Smith, David H Fukuda, Kristina L Kendall & Jeffrey R Stout. (2010) The effects of a pre-workout supplement containing caffeine, creatine, and amino acids during three weeks of high-intensity exercise on aerobic and anaerobic performance. Journal of the International Society of Sports Nutrition 7:1.
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RN Rodseth & BM Biccard. (2009) Living longer as an anaesthetist: The ‘magic’ lifestyle or the ‘lifestyle polypill’. Southern African Journal of Anaesthesia and Analgesia 15:4, pages 5-10.
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Ashley A Walter, Trent J Herda, Eric D Ryan, Pablo B Costa, Katherine M Hoge, Travis W Beck, Jeffery R Stout & Joel T Cramer. (2009) Acute effects of a thermogenic nutritional supplement on cycling time to exhaustion and muscular strength in college-aged men. Journal of the International Society of Sports Nutrition 6:1.
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David F. Carrageta, Tânia R. Dias, Ivana Jarak, Marco G. Alves, Pedro F. Oliveira, Mietha M. Van der Walt, Gisella Terre'Blanche, Mariana P. Monteiro & Branca M. Silva. (2018) 8-(3-phenylpropyl)-1,3,7-triethylxanthine is a synthetic caffeine substitute with stronger metabolic modulator activity. Toxicology in Vitro 53, pages 114-120.
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Jason Tallis, Matthew F. Higgins, Val M. Cox, Michael J. Duncan & Rob S. James. (2018) An exercise-induced improvement in isolated skeletal muscle contractility does not affect the performance-enhancing benefit of 70 µmol l−1 caffeine treatment. Journal of Experimental Biology 221:21.
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Mayur K. Ranchordas, George King, Mitchell Russell, Anthony Lynn & Mark Russell. (2018) Effects of Caffeinated Gum on a Battery of Soccer-Specific Tests in Trained University-Standard Male Soccer Players. International Journal of Sport Nutrition and Exercise Metabolism 28:6, pages 629-634.
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B.A. Dearlove, K.L. Kind, K.L. Gatford & W.H.E.J. van Wettere. (2018) Oral caffeine administered during late gestation increases gestation length and piglet temperature in naturally farrowing sows. Animal Reproduction Science 198, pages 160-166.
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Leah M. Panek-Shirley, Carol DeNysschen, Erin O’Brien & Jennifer L. Temple. (2018) Caffeine Transiently Affects Food Intake at Breakfast. Journal of the Academy of Nutrition and Dietetics 118:10, pages 1832-1843.
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Kyle Southward, Kay J. Rutherfurd-Markwick & Ajmol Ali. (2018) Correction to: The Effect of Acute Caffeine Ingestion on Endurance Performance: A Systematic Review and Meta-Analysis. Sports Medicine 48:10, pages 2425-2441.
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Jacob Fulton, Petros Dinas, Andres Carrillo, Jason Edsall, Emily Ryan & Edward Ryan. (2018) Impact of Genetic Variability on Physiological Responses to Caffeine in Humans: A Systematic Review. Nutrients 10:10, pages 1373.
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