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Research Article

Estrogen Receptors: Role in Breast Cancer

Pages 325-347 | Published online: 10 Oct 2008

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Sarbajit Ray, Suchetana Gupta, Gayatri Panda, Prarthana Chatterjee, Anoushka Das, Purvi Patawri, Parisa Hosseinzadeh, Arjun Ray & Satarupa Banerjee. (2023) Identification of pseudobaptigenin as a novel polyphenol-based multi-target antagonist of different hormone receptors for breast cancer therapeutics. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-13.
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Ram Sharma & Vikas Jaitak. (2020) Asparagus racemosus (Shatavari) targeting estrogen receptor α: - An in-vitro and in-silico mechanistic study. Natural Product Research 34:11, pages 1571-1574.
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Michael J. Duffy & John Crown. (2014) Precision treatment for cancer: Role of prognostic and predictive markers. Critical Reviews in Clinical Laboratory Sciences 51:1, pages 30-45.
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Kelly T Huynh, Kelly K Chong, Edward S Greenberg & Dave SB Hoon. (2012) Epigenetics of estrogen receptor-negative primary breast cancer. Expert Review of Molecular Diagnostics 12:4, pages 371-382.
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Articles from other publishers (65)

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Muhammed Gömeç, Koray Sayin, Mustafa Özkaraca & Hüseyin Özden. (2022) Synthesis, in silico and investigation of anti-breast cancer activity of new diphenyl urea derivatives: Experimental and computational study. Journal of Molecular Structure 1265, pages 133414.
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Xi Chen, Xu Shi, Andrew F. Neuwald, Leena Hilakivi-Clarke, Robert Clarke & Jianhua Xuan. (2021) ChIP-BIT2: a software tool to detect weak binding events using a Bayesian integration approach. BMC Bioinformatics 22:1.
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Inamul Haque, Arnab Ghosh, Seth Acup, Snigdha Banerjee, Kakali Dhar, Amitabha Ray, Sandipto Sarkar, Suman Kambhampati & Sushanta K. Banerjee. (2018) Leptin-induced ER-α-positive breast cancer cell viability and migration is mediated by suppressing CCN5-signaling via activating JAK/AKT/STAT-pathway. BMC Cancer 18:1.
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Xuan Li, Danian Dai, Bo Chen, Hailin Tang, Xiaoming Xie & Weidong Wei. (2018) Clinicopathological and Prognostic Significance of Cancer Antigen 15-3 and Carcinoembryonic Antigen in Breast Cancer: A Meta-Analysis including 12,993 Patients. Disease Markers 2018, pages 1-15.
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Yasset Perez-Riverol, Max Kuhn, Juan Antonio Vizcaíno, Marc-Phillip Hitz & Enrique Audain. (2017) Accurate and fast feature selection workflow for high-dimensional omics data. PLOS ONE 12:12, pages e0189875.
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G. E. Morozevich, N. I. Kozlova, O. Y. Susova, A. Y. Lupatov & A. E. Berman. (2017) Hyperexpression of integrin α5β1 promotes resistance of MCF-7 human breast carcinoma cells to doxorubicin via ERK protein kinase down-regulation. Biochemistry (Moscow) 82:9, pages 1017-1024.
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Michael J. Duffy, Siun Walsh, Enda W. McDermott & John Crown. 2015. 1 23 .
Matthew Brennan & Bora Lim. 2015. Advances in Cancer Biomarkers. Advances in Cancer Biomarkers 327 337 .
Lei Zhang, Yantao Han, Qixiao Jiang, Chunbo Wang, Xuehong Chen, Xiaoguang Li, Fuming Xu, Yuqi Jiang, Qiang Wang & Wenfang Xu. (2015) Trend of Histone Deacetylase Inhibitors in Cancer Therapy: Isoform Selectivity or Multitargeted Strategy. Medicinal Research Reviews 35:1, pages 63-84.
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Michael J Duffy, Patricia M McGowan, Nadia Harbeck, Christoph Thomssen & Manfred Schmitt. (2014) uPA and PAI-1 as biomarkers in breast cancer: validated for clinical use in level-of-evidence-1 studies. Breast Cancer Research 16:4.
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Crossref
Nicholas C. Dracopoli & Katie Streicher. 2014. Genomic Biomarkers for Pharmaceutical Development. Genomic Biomarkers for Pharmaceutical Development 23 49 .
RUPNINDER SANDHU, ASHLEY G. RIVENBARK & WILLIAM B. COLEMAN. (2012) Loss of post-transcriptional regulation of DNMT3b by microRNAs: A possible molecular mechanism for the hypermethylation defect observed in a subset of breast cancer cell lines. International Journal of Oncology 41:2, pages 721-732.
Crossref
Asit K Paul & Richard B Schwab. (2012) Efficacy and pharmacogenomic biomarkers in breast cancer. Biomarkers in Medicine 6:2, pages 211-221.
Crossref
A. Phinyomark, S. Jitaree, P. Phukpattaranont & P. Boonyapiphat. (2012) Texture Analysis of Breast Cancer Cells in Microscopic Images Using Critical Exponent Analysis Method. Procedia Engineering 32, pages 232-238.
Crossref
Rupninder Sandhu, Ashley G. Rivenbark & William B. Coleman. (2011) Enhancement of chemotherapeutic efficacy in hypermethylator breast cancer cells through targeted and pharmacologic inhibition of DNMT3b. Breast Cancer Research and Treatment 131:2, pages 385-399.
Crossref
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Crossref
Emily Sonestedt & Elisabet Wirfält. (2010) Enterolactone and breast cancer: methodological issues may contribute to conflicting results in observational studies. Nutrition Research 30:10, pages 667-677.
Crossref
Maria P Pavlou, Vathany Kulasingam, Edward R Sauter, Beth Kliethermes & Eleftherios P Diamandis. (2010) Nipple Aspirate Fluid Proteome of Healthy Females and Patients with Breast Cancer. Clinical Chemistry 56:5, pages 848-855.
Crossref
Sondes Karray-Chouayekh, Fatma Trifa, Abdelmajid Khabir, Nouredine Boujelbane, Tahia Sellami-Boudawara, Jamel Daoud, Mounir Frikha, Rachid Jlidi, Ali Gargouri & Raja Mokdad-Gargouri. (2009) Aberrant methylation of RASSF1A is associated with poor survival in Tunisian breast cancer patients. Journal of Cancer Research and Clinical Oncology 136:2, pages 203-210.
Crossref
Hugo Arias-Pulido, Harriet O. Smith, Nancy E. Joste, Therese Bocklage, Clifford R. Qualls, Allison Chavez, Eric R. Prossnitz & Claire F. Verschraegen. (2009) Estrogen and progesterone receptor status and outcome in epithelial ovarian cancers and low malignant potential tumors. Gynecologic Oncology 114:3, pages 480-485.
Crossref
Mirjam Froehlicher, Anja Liedtke, Ksenia Groh, Hernán López-Schier, Stephan C.F. Neuhauss, Helmut Segner & Rik I.L. Eggen. (2009) Estrogen receptor subtype β2 is involved in neuromast development in zebrafish (Danio rerio) larvae. Developmental Biology 330:1, pages 32-43.
Crossref
Emily Sonestedt, Malin I.L. Ivarsson, Sophia Harlid, Ulrika Ericson, Bo Gullberg, Joyce Carlson, Håkan Olsson, Herman Adlercreutz & Elisabet Wirfält. (2009) The Protective Association of High Plasma Enterolactone with Breast Cancer Is Reasonably Robust in Women with Polymorphisms in the Estrogen Receptor α and β Genes. The Journal of Nutrition 139:5, pages 993-1001.
Crossref
Sondes Karray-Chouayekh, Fatma Trifa, Abdelmajid Khabir, Nouredine Boujelbane, Tahia Sellami-Boudawara, Jamel Daoud, Mounir Frikha, Ali Gargouri & Raja Mokdad-Gargouri. (2009) Clinical Significance of Epigenetic Inactivation of hMLH1 and BRCA1 in Tunisian Patients with Invasive Breast Carcinoma. Journal of Biomedicine and Biotechnology 2009, pages 1-7.
Crossref
Catharine M Sturgeon, Michael J Duffy, Ulf-Håkan Stenman, Hans Lilja, Nils Brünner, Daniel W Chan, Richard Babaian, Robert C BastJr.Jr., Barry Dowell, Francisco J Esteva, Caj Haglund, Nadia Harbeck, Daniel F Hayes, Mads Holten-Andersen, George G Klee, Rolf Lamerz, Leendert H Looijenga, Rafael Molina, Hans Jørgen Nielsen, Harry Rittenhouse, Axel Semjonow, Ie-Ming Shih, Paul Sibley, György Sölétormos, Carsten Stephan, Lori Sokoll, Barry R Hoffman & Eleftherios P Diamandis. (2008) National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines for Use of Tumor Markers in Testicular, Prostate, Colorectal, Breast, and Ovarian Cancers. Clinical Chemistry 54:12, pages e11-e79.
Crossref
Michael J Duffy & John Crown. (2008) A Personalized Approach to Cancer Treatment: How Biomarkers Can Help. Clinical Chemistry 54:11, pages 1770-1779.
Crossref
Emily Sonestedt, Signe Borgquist, Ulrika Ericson, Bo Gullberg, Håkan Olsson, Herman Adlercreutz, Göran Landberg & Elisabet Wirfält. (2008) Enterolactone Is Differently Associated with Estrogen Receptor β–Negative and –Positive Breast Cancer in a Swedish Nested Case-Control Study. Cancer Epidemiology, Biomarkers & Prevention 17:11, pages 3241-3251.
Crossref
E McKiernan, K O'Brien, N Grebenchtchikov, A Geurts-Moespot, A M Sieuwerts, J W M Martens, V Magdolen, D Evoy, E McDermott, J Crown, F C G J Sweep & M J Duffy. (2008) Protein kinase Cδ expression in breast cancer as measured by real-time PCR, western blotting and ELISA. British Journal of Cancer 99:10, pages 1644-1650.
Crossref
P Lagiou, C-C Hsieh, D Trichopoulos, H-O Adami, P Hall, L Chie & A Ekbom. (2008) Neonatal growth and breast cancer risk in adulthood. British Journal of Cancer 99:9, pages 1544-1548.
Crossref
E. Sonestedt, S. Borgquist, U. Ericson, B. Gullberg, G. Landberg, H. Olsson & E. Wirfalt. (2008) Plant foods and oestrogen receptor  - and  -defined breast cancer: observations from the Malmo Diet and Cancer cohort. Carcinogenesis 29:11, pages 2203-2209.
Crossref
Dmitry A. Turbin, Samuel Leung, Maggie C. U. Cheang, Hagen A. Kennecke, Kelli D. Montgomery, Steven McKinney, Diana O. Treaba, Niki Boyd, Lynn C. Goldstein, Sunil Badve, Allen M. Gown, Matt van de Rijn, Torsten O. Nielsen, C. Blake Gilks & David G. Huntsman. (2007) Automated quantitative analysis of estrogen receptor expression in breast carcinoma does not differ from expert pathologist scoring: a tissue microarray study of 3,484 cases. Breast Cancer Research and Treatment 110:3, pages 417-426.
Crossref
Eiji Sunami, Masaru Shinozaki, Myung-Shin Sim, Sandy L Nguyen, Anh-Thu Vu, Armando E Giuliano & Dave SB Hoon. (2008) Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors. Breast Cancer Research 10:3.
Crossref
P.M. McGowan, E. McKiernan, F. Bolster, B.M. Ryan, A.D.K. Hill, E.W. McDermott, D. Evoy, N. O'Higgins, J. Crown & M.J. Duffy. (2008) ADAM-17 predicts adverse outcome in patients with breast cancer. Annals of Oncology 19:6, pages 1075-1081.
Crossref
Claudia Casarsa, Saro Oriana & Danila Coradini. (2008) The Controversial Clinicobiological Role of Breast Cancer Stem Cells. Journal of Oncology 2008, pages 1-12.
Crossref
Marcia S. Driscoll & Jane M. Grant-Kels. (2007) Hormones, nevi, and melanoma: An approach to the patient. Journal of the American Academy of Dermatology 57:6, pages 919-931.
Crossref
K.J. Pawlak & J.P. Wiebe. (2007) Regulation of estrogen receptor (ER) levels in MCF-7 cells by progesterone metabolites. The Journal of Steroid Biochemistry and Molecular Biology 107:3-5, pages 172-179.
Crossref
Michael J. Duffy. (2007) Role of tumor markers in patients with solid cancers: A critical review. European Journal of Internal Medicine 18:3, pages 175-184.
Crossref
Abhik Bandyopadhyay, Long Wang, Shiau Hui Chin & Lu-Zhe Sun. (2007) Inhibition of Skeletal Metastasis by Ectopic ERα Expression in ERα-Negative Human Breast Cancer Cell Lines. Neoplasia 9:2, pages 113-118.
Crossref

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