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Review Article

Role of resveratrol in the management of insulin resistance and related conditions: Mechanism of action

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Pages 267-293 | Received 28 Feb 2017, Accepted 13 Jun 2017, Published online: 13 Jul 2017

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Read on this site (7)

Zhenfeng Xie & Xing Chen. (2023) Healthy benefits and edible delivery systems of resveratrol: a review. Food Reviews International 39:7, pages 3879-3905.
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Linyi Shu, Hang Zhao, Wenli Huang, Guangsen Hou, Guangyao Song & Huijuan Ma. (2020) Resveratrol Upregulates mmu-miR-363-3p via the PI3K-Akt Pathway to Improve Insulin Resistance Induced by a High-Fat Diet in Mice. Diabetes, Metabolic Syndrome and Obesity 13, pages 391-403.
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Roohollah Mohseni, Zahra Arab Sadeghabadi, Mohammad Taghi Goodarzi & Jamshid Karimi. (2019) Co-administration of resveratrol and beta-aminopropionitrile attenuates liver fibrosis development via targeting lysyl oxidase in CCl4-induced liver fibrosis in rats. Immunopharmacology and Immunotoxicology 41:6, pages 644-651.
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Abbas Ali Sangouni, Shima Abdollahi & Hassan Mozaffari-Khosravi. (2022) Effect of resveratrol supplementation on hepatic steatosis and cardiovascular indices in overweight subjects with type 2 diabetes: a double-blind, randomized controlled trial. BMC Cardiovascular Disorders 22:1.
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Fereshteh Mehri, Akram Ranjbar, Naghmeh Shirafkan, Sara S. Asl & Maryam Esfahani. (2022) The protective effect of resveratrol on diazinon‐induced oxidative stress and glucose hemostasis disorder in rats' liver. Journal of Biochemical and Molecular Toxicology 36:7.
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Bean bu Kang & Been huang Chiang. (2022) A novel phenolic formulation for treating hepatic and peripheral insulin resistance by regulating GLUT4-mediated glucose uptake. Journal of Traditional and Complementary Medicine 12:2, pages 195-205.
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Zhihong Liu, Zhimei Zhang, Guangyao Song, Xing Wang, Hanying Xing & Chao Wang. (2022) Resveratrol Alleviates Skeletal Muscle Insulin Resistance by Downregulating Long Noncoding RNA. International Journal of Endocrinology 2022, pages 1-16.
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Ke-Xue Li, Miao-Jin Ji & Hai-Jian Sun. (2021) An updated pharmacological insight of resveratrol in the treatment of diabetic nephropathy. Gene 780, pages 145532.
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Jay Jay Thaung Zaw, Peter RC. Howe & Rachel HX. Wong. (2021) Long-term effects of resveratrol on cognition, cerebrovascular function and cardio-metabolic markers in postmenopausal women: A 24-month randomised, double-blind, placebo-controlled, crossover study. Clinical Nutrition 40:3, pages 820-829.
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Keryn G. Woodman, Chantal A. Coles, Shireen R. Lamandé & Jason D. White. (2021) Resveratrol Promotes Hypertrophy in Wildtype Skeletal Muscle and Reduces Muscle Necrosis and Gene Expression of Inflammatory Markers in Mdx Mice. Molecules 26:4, pages 853.
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Marco A. Perrone, Jagadish Babu Dasari, Alfredo Intorcia, Paola Gualtieri, Massimo Marche, Marco Di Luozzo, Giuseppe Merra, Sergio Bernardini, Francesco Romeo & Domenico Sergi. (2020) Phenotypic classification and biochemical profile of obesity for cardiovascular prevention. Gazzetta Medica Italiana Archivio per le Scienze Mediche 179:5.
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Vanesa Cepas, Massimo Collino, Juan C. Mayo & Rosa M. Sainz. (2020) Redox Signaling and Advanced Glycation Endproducts (AGEs) in Diet-Related Diseases. Antioxidants 9:2, pages 142.
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Mahshid Hodjat, Madiha Khalid, Mona Asghari, Sepideh Atri, Mahban Rahimifard, Solmaz Mohammadi Nejad & Maryam Baeeri. 2020. Nutrients and Nutraceuticals for Active & Healthy Ageing. Nutrients and Nutraceuticals for Active & Healthy Ageing 63 109 .
Roohollah Mohseni, Zahra ArabSadeghabadi, Nasrin Ziamajidi, Roghayeh Abbasalipourkabir & Azam RezaeiFarimani. (2019) Oral Administration of Resveratrol-Loaded Solid Lipid Nanoparticle Improves Insulin Resistance Through Targeting Expression of SNARE Proteins in Adipose and Muscle Tissue in Rats with Type 2 Diabetes. Nanoscale Research Letters 14:1.
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Maryam Bahmanzadeh, Mohammad Taghi Goodarzi, Azam Rezaei Farimani, Nasibeh Fathi & Zohreh Alizadeh. (2019) Resveratrol supplementation improves DNA integrity and sperm parameters in streptozotocin–nicotinamide‐induced type 2 diabetic rats. Andrologia 51:8.
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Fatemeh Mirzaei, Mozafar Khazaei, Alireza Komaki, Iraj Amiri & Cyrus Jalili. (2019) Multitarget Effects of Coconut Oil (Virgin Type) on Aβ-Induced Alzheimer’s Disease Animal Model. Archives of Neuroscience In Press:In Press.
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Jongdee Nopparat, Aekkaraj Nualla-ong & Amornrat Phongdara. (2019) Ethanolic extracts of Pluchea indica (L.) leaf pretreatment attenuates cytokine-induced β-cell apoptosis in multiple low-dose streptozotocin-induced diabetic mice. PLOS ONE 14:2, pages e0212133.
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Chahinez Houacine & Kamalinder K. Singh. 2018. NanoNutraceuticals. NanoNutraceuticals 165 182 .
S. Salehi, MR. Bayatiani, P. Yaghmaei, S. Rajabi, MT. Goodarzi & F. Jalali Mashayekhi. (2018) Protective effects of resveratrol against X-ray irradiation by regulating antioxidant defense system. Radioprotection 53:4, pages 293-298.
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Rachel Wong & Peter Howe. (2018) Resveratrol Counteracts Insulin Resistance—Potential Role of the Circulation. Nutrients 10:9, pages 1160.
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Zülbiye Yılmaz, Esra Betül Kalaz, A. Fatih Aydın, Vakur Olgaç, Semra Doğru-Abbasoğlu, Müjdat Uysal & Necla Koçak-Toker. (2018) The effect of resveratrol on glycation and oxidation products in plasma and liver of chronic methylglyoxal-treated rats. Pharmacological Reports 70:3, pages 584-590.
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Dong Kwon Yang & Hyung-Sub Kang. (2018) Anti-Diabetic Effect of Cotreatment with Quercetin and Resveratrol in Streptozotocin-Induced Diabetic Rats. Biomolecules & Therapeutics 26:2, pages 130-138.
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Shaojian Ji, Amir Fattahi, Nathalie Raffel, Inge Hoffmann, Matthias W. Beckmann, Ralf Dittrich & Michael Schrauder. (2017) Antioxidant effect of aqueous extract of four plants with therapeutic potential on gynecological diseases; Semen persicae, Leonurus cardiaca, Hedyotis diffusa, and Curcuma zedoaria. European Journal of Medical Research 22:1.
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