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Isolation and Characterization of Peptides with Antihypertensive Activity in Foodstuffs

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Keval Chopada, Bethsheba Basaiawmoit, Amar A. Sakure, Ruchika Maurya, Mahendra Bishnoi, Kanthi Kiran Kondepudi, Divyang Solanki, B. P. Singh, Srichandan Padhi, Amit Kumar Rai, Zhenbin Liu, B. K. Mishra & Subrota Hati. (2023) Purification and Characterization of Novel Antihypertensive and Antioxidative Peptides From Whey Protein Fermentate: In Vitro, In Silico, and Molecular Interactions Studies. Journal of the American Nutrition Association 42:6, pages 598-617.
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Chaudhari Hiralben Mansinhbhai, Amar Sakure, Zhenbin Liu, Ruchika Maurya, Sujit Das, Bethsheba Basaiawmoit, Mahendra Bishnoi, Kanthi Kiran Kondepudi, Srichandan Padhi, Amit Kumar Rai, Birendra K. Mishra & Subrota Hati. (2023) Anti-Inflammatory, ACE Inhibitory, Antioxidative Activities and Release of Novel Antihypertensive and Antioxidative Peptides from Whey Protein Hydrolysate with Molecular Interactions. Journal of the American Nutrition Association 42:4, pages 371-385.
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Sima Maleki & Seyed Hadi Razavi. (2021) Pulses’ germination and fermentation: Two bioprocessing against hypertension by releasing ACE inhibitory peptides. Critical Reviews in Food Science and Nutrition 61:17, pages 2876-2893.
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Ji Yeon Kim, Doram Kim & Oran Kwon. (2016) Effective screening for the anti-hypertensive of selected herbs used in the traditional Korean medicines. Applied Biological Chemistry 59:4, pages 525-532.
Crossref
Taskeen Niaz, Saima Shabbir, Shahid Manzoor, Asma Rehman, Abdur Rahman, Habib Nasir & Muhammad Imran. (2016) Antihypertensive nano-ceuticales based on chitosan biopolymer: Physico-chemical evaluation and release kinetics. Carbohydrate Polymers 142, pages 268-274.
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Rong He, Abraham T. Girgih, Elodie Rozoy, Laurent Bazinet, Xing-Rong Ju & Rotimi E. Aluko. (2016) Selective separation and concentration of antihypertensive peptides from rapeseed protein hydrolysate by electrodialysis with ultrafiltration membranes. Food Chemistry 197, pages 1008-1014.
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Mohsen Mazidi, Peyman Rezaie, Andre Pascal Kengne, Majid Ghayour Mobarhan & Gordon A. Ferns. (2016) Gut microbiome and metabolic syndrome. Diabetes & Metabolic Syndrome: Clinical Research & Reviews 10:2, pages S150-S157.
Crossref
M.C. García, J.M. Orellana & M.L. Marina. 2016. Protein Byproducts. Protein Byproducts 193 211 .
Manuel Nuñez & Margarita Medina. 2016. Reference Module in Food Science. Reference Module in Food Science.
Estefanía González-García, Patrycja Puchalska, María Luisa Marina & María Concepción García. (2015) Fractionation and identification of antioxidant and angiotensin-converting enzyme-inhibitory peptides obtained from plum (Prunus domestica L.) stones. Journal of Functional Foods 19, pages 376-384.
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Anna Arnoldi, Giovanna Boschin, Chiara Zanoni & Carmen Lammi. (2015) The health benefits of sweet lupin seed flours and isolated proteins. Journal of Functional Foods 18, pages 550-563.
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Carmen Lammi, Chiara Zanoni, Anna Arnoldi & Giulio Vistoli. (2015) Two Peptides from Soy β-Conglycinin Induce a Hypocholesterolemic Effect in HepG2 Cells by a Statin-Like Mechanism: Comparative in Vitro and in Silico Modeling Studies. Journal of Agricultural and Food Chemistry 63:36, pages 7945-7951.
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Ravi Kumar, Kumardeep Chaudhary, Jagat Singh Chauhan, Gandharva Nagpal, Rahul Kumar, Minakshi Sharma & Gajendra P.S. Raghava. (2015) An in silico platform for predicting, screening and designing of antihypertensive peptides. Scientific Reports 5:1.
Crossref
Luca Dellafiora, Sara Paolella, Chiara Dall’Asta, Arnaldo Dossena, Pietro Cozzini & Gianni Galaverna. (2015) Hybrid in Silico/in Vitro Approach for the Identification of Angiotensin I Converting Enzyme Inhibitory Peptides from Parma Dry-Cured Ham. Journal of Agricultural and Food Chemistry 63:28, pages 6366-6375.
Crossref
Xueran Geng, Guoting Tian, Weiwei Zhang, Yongchang Zhao, Liyan Zhao, Mansok Ryu, Hexiang Wang & Tzi Ng. (2015) Isolation of an Angiotensin I-Converting Enzyme Inhibitory Protein with Antihypertensive Effect in Spontaneously Hypertensive Rats from the Edible Wild Mushroom Leucopaxillus tricolor. Molecules 20:6, pages 10141-10153.
Crossref
María Concepción García, Jochan Endermann, Estefanía González-García & María Luisa Marina. (2015) HPLC-Q-TOF-MS Identification of Antioxidant and Antihypertensive Peptides Recovered from Cherry ( Prunus cerasus L.) Subproducts . Journal of Agricultural and Food Chemistry 63:5, pages 1514-1520.
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