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Original Articles

The Effects of Sucrose on Metabolic Health: A Systematic Review of Human Intervention Studies in Healthy Adults

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Pages 591-614 | Published online: 05 Apr 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Stein Egil Kolderup Hervik, Astrid Kolderup Hervik & Miranda Thurston. (2022) From science to sensational headline: a critical examination of the “sugar as toxic” narrative. Food, Culture & Society 25:3, pages 505-519.
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Carolina Gabriela Plazas Guerrero, Selene De Jesús Acosta Cota, Francisco Humberto Castro Sánchez, Marcela De Jesús Vergara Jiménez, Efrén Rafael Ríos Burgueño, Juan Ignacio Sarmiento Sánchez, Lorenzo Antonio Picos Corrales & Ulises Osuna Martínez. (2021) Evaluation of sucrose-enriched diet consumption in the development of risk factors associated to type 2 diabetes, atherosclerosis and non-alcoholic fatty liver disease in a murine model. International Journal of Environmental Health Research 31:6, pages 651-669.
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Articles from other publishers (30)

Ramsheela Vishwakarma, Bina Gidwani, Ravindra Kumar Pandey & Shiv Shankar Shukla. (2023) Analytical Method, Chemistry and Properties of Fructose, Sucrose and Ascorbic Acid in Pear Fruit Juice. International Journal of Pharmaceutical Research and Allied Sciences 12:3, pages 28-45.
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Dimas Rahadian Aji Muhammad, Muhammad Zukhrufuz Zaman & Achmad Ridwan Ariyantoro. 2023. Sustainable Development and Pathways for Food Ecosystems. Sustainable Development and Pathways for Food Ecosystems 147 182 .
Dingze Mang, Kasubuchi Mayu, Tomoko Toyama, Takayuki Yamagishi & Ryoichi Sato. (2022) BmGr4 responds to sucrose and glucose and expresses in tachykinin-related peptide-secreting enteroendocrine cells. Insect Biochemistry and Molecular Biology 150, pages 103858.
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Chinmoy Sarkar, Ka Yan Lai, Rong Zhang, Michael Y. Ni & Chris Webster. (2022) The association between workplace built environment and metabolic health: A systematic review and meta-analysis. Health & Place 76, pages 102829.
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Pamela Mattar, Lilian Toledo‐Valenzuela, María Paz Hernández‐Cáceres, Daniel Peña‐Oyarzún, Eugenia Morselli & Claudio Perez‐Leighton. (2022) Integrating the effects of sucrose intake on the brain and white adipose tissue: Could autophagy be a possible link?. Obesity 30:6, pages 1143-1155.
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Camila V.M. Silva, Joana R.C. Santos, M. Melia Rodrigo, Ana C.F. Ribeiro, Artur J.M. Valente, Paulo E. Abreu, Jorge M.C. Marques & Miguel A. Esteso. (2022) On the transport and dynamics of disaccharides: H-bonding effect in sucrose and sucralose. Journal of Molecular Liquids 345, pages 117855.
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Margaux R. Mora & Robin Dando. (2021) The sensory properties and metabolic impact of natural and synthetic sweeteners. Comprehensive Reviews in Food Science and Food Safety 20:2, pages 1554-1583.
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Lucía Camacho-Barcia, Jesús García-Gavilán, Christopher Papandreou, Thea T. Hansen, Jo A. Harrold, Graham Finlayson, John E. Blundell, Anders Sjödin, Jason C. G. Halford & Mònica Bulló. (2021) Circulating Metabolites Associated with Postprandial Satiety in Overweight/Obese Participants: The SATIN Study. Nutrients 13:2, pages 549.
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Marion Valle, Philippe St-Pierre, Geneviève Pilon & André Marette. (2020) Differential Effects of Chronic Ingestion of Refined Sugars versus Natural Sweeteners on Insulin Resistance and Hepatic Steatosis in a Rat Model of Diet-Induced Obesity. Nutrients 12:8, pages 2292.
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Anh N. Nguyen, Susana Santos, Kim V. E. Braun & Trudy Voortman. (2020) Carbohydrate Intake in Early Childhood and Body Composition and Metabolic Health: Results from the Generation R Study. Nutrients 12:7, pages 1940.
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Sabine Weiskirchen, Katharina Weiper, René H. Tolba & Ralf Weiskirchen. (2020) All You Can Feed: Some Comments on Production of Mouse Diets Used in Biomedical Research with Special Emphasis on Non-Alcoholic Fatty Liver Disease Research. Nutrients 12:1, pages 163.
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Peter Clifton. (2019) Metabolic Syndrome—Role of Dietary Fat Type and Quantity. Nutrients 11:7, pages 1438.
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Riccardo Baschetti. (2019) Evolutionary physiology shows the need for an unprecedented study on sugar. Clinical Nutrition ESPEN 31, pages 23-27.
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Owen Kelly, Jennifer Gilman & Jasminka Ilich. (2019) Utilizing Dietary Nutrient Ratios in Nutritional Research: Expanding the Concept of Nutrient Ratios to Macronutrients. Nutrients 11:2, pages 282.
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David J Tybor, Andrew R Beauchesne, Ruijia Niu, Marissa M Shams-White & Mei Chung. (2018) An Evidence Map of Research Linking Dietary Sugars to Potentially Related Health Outcomes. Current Developments in Nutrition 2:11, pages nzy059.
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Aya Fujiwara, Kentaro Murakami, Keiko Asakura, Ken Uechi, Minami Sugimoto, Han-Chieh Wang, Shizuko Masayasu & Satoshi Sasaki. (2018) Estimation of Starch and Sugar Intake in a Japanese Population Based on a Newly Developed Food Composition Database. Nutrients 10:10, pages 1474.
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Sweety Mathew, Anna Halama, Sara Abdul Kader, Minkyung Choe, Robert P. Mohney, Joel A. Malek & Karsten Suhre. (2018) Metabolic changes of the blood metabolome after a date fruit challenge. Journal of Functional Foods 49, pages 267-276.
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. (2018) Protocol for the scientific opinion on the Tolerable Upper Intake Level of dietary sugars. EFSA Journal 16:8.
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Eva Gatineau, Sergio Polakof, Dominique Dardevet & Laurent Mosoni. (2017) Similarities and interactions between the ageing process and high chronic intake of added sugars. Nutrition Research Reviews 30:2, pages 191-207.
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Hailin Feng, Zhiyi Huang, Xiongwei Lou, Jian Li & Guohua Hui. (2016) Study of a Sucrose Sensor by Functional Cu Foam Material and Its Applications in Commercial Beverages. Food Analytical Methods 10:2, pages 407-418.
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Ulrike Schuhmacher-Wolz, Jens-Uwe Voss & Klaus Schneider. (2017) Case study with natural substances on the various options to identify and categorise endocrine disruptors. Journal of Toxicology and Health 4:1, pages 2.
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Bruno Araújo Serra Pinto, Thamys Marinho Melo, Karla Frida Torres Flister, Lucas Martins França, Daniela Kajihara, Leonardo Yuji Tanaka, Francisco Rafael Martins Laurindo & Antonio Marcus de Andrade Paes. (2016) Early and sustained exposure to high-sucrose diet triggers hippocampal ER stress in young rats. Metabolic Brain Disease 31:4, pages 917-927.
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Kara R. Goldfein & Joanne L. Slavin. (2015) Why Sugar Is Added to Food: Food Science 101. Comprehensive Reviews in Food Science and Food Safety 14:5, pages 644-656.
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B. A. Griffin. (2015) Relevance of liver fat to the impact of dietary extrinsic sugars on lipid metabolism. Proceedings of the Nutrition Society 74:3, pages 208-214.
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Vanessa Ha, Adrian I Cozma, Vivian LW Choo, Sonia Blanco Mejia, Russell J de Souza & John L Sievenpiper. (2015) Do Fructose-Containing Sugars Lead to Adverse Health Consequences? Results of Recent Systematic Reviews and Meta-analyses. Advances in Nutrition 6:4, pages 504-511.
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Miloslava Hodúlová, Lucie Šedová, Drahomíra Křenová, František Liška, Michaela Krupková, Ludmila Kazdová, Johanne Tremblay, Pavel Hamet, Vladimír Křen & Ondřej Šeda. (2014) Genomic Determinants of Triglyceride and Cholesterol Distribution into Lipoprotein Fractions in the Rat. PLoS ONE 9:10, pages e109983.
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Erik Arnesen. (2014) “Søtt og farlig” av Robert Lustig. Norsk tidsskrift for ernæring 12:3, pages 44-49.
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M. Murphy. (2014) Dietary guidelines: Scientific substantiation and public health impact. Nutrition Bulletin 39:3, pages 290-304.
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Lisa A Te Morenga, Alex J Howatson, Rhiannon M Jones & Jim Mann. (2014) Dietary sugars and cardiometabolic risk: systematic review and meta-analyses of randomized controlled trials of the effects on blood pressure and lipids,,. The American Journal of Clinical Nutrition 100:1, pages 65-79.
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John L. Sievenpiper. 2014. Fructose, High Fructose Corn Syrup, Sucrose and Health. Fructose, High Fructose Corn Syrup, Sucrose and Health 113 123 .