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Cucurmin, anticancer, & antitumor perspectives: A comprehensive review

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Muhammad Imran, Farhan Saeed, Suliman A. Alsagaby, Ali Imran, Ishtiaque Ahmad, Ahmad H. El Ghorab, Mohamed A. Abdelgawad, Tahira Batool Qaisrani, Tahir Mehmood, Maryam Umar, Muhammad Arslan Mumtaz, Arfaa Sajid, Qaisar Manzoor, Muzzamal Hussain, Waleed Al Abdulmonem & Entessar Al Jbawi. (2023) Curcumin: recent updates on gastrointestinal cancers. CyTA - Journal of Food 21:1, pages 502-513.
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Ming-Hsien Chien, Pei-Chun Shih, Yi-Fang Ding, Li-Hsin Chen, Feng-Koo Hsieh, Meng-Ying Tsai, Pei-Yi Li, Chiao-Wen Lin & Shun-Fa Yang. (2022) Curcumin analog, GO-Y078, induces HO-1 transactivation-mediated apoptotic cell death of oral cancer cells by triggering MAPK pathways and AP-1 DNA-binding activity. Expert Opinion on Therapeutic Targets 26:4, pages 375-388.
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Xusheng Li, Zilan Yao, Xinwei Jiang, Jianxia Sun, Guojing Ran, Xuan Yang, Yaqi Zhao, Ying Yan, Zisheng Chen, Lingmin Tian & Weibin Bai. (2020) Bioactive compounds from Cudrania tricuspidata: A natural anticancer source. Critical Reviews in Food Science and Nutrition 60:3, pages 494-514.
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Amlan Kumar Patra, Salah Amasheh & Jörg Rudolf Aschenbach. (2019) Modulation of gastrointestinal barrier and nutrient transport function in farm animals by natural plant bioactive compounds – A comprehensive review. Critical Reviews in Food Science and Nutrition 59:20, pages 3237-3266.
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Malleswara Rao Peram, Sunil Jalalpure, Vijay Kumbar, Sachin Patil, Sumit Joshi, Kishore Bhat & Prakash Diwan. (2019) Factorial design based curcumin ethosomal nanocarriers for the skin cancer delivery: in vitro evaluation. Journal of Liposome Research 29:3, pages 291-311.
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Xin Yin, Muhammad Aslam Khan, Paul Van der Meeren, Shuai Feng, Yongchao Wang & Li Liang. (2023) pH-driven preparation of caseinate-chitosan complex coacervation for co-encapsulation of hydrophobic curcumin and hydrophilic l-ascorbate: Stability and in vitro release properties. Food Bioscience 56, pages 103420.
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Rasanpreet Kaur, Alok Bhardwaj & Saurabh Gupta. (2023) Cancer treatment therapies: traditional to modern approaches to combat cancers. Molecular Biology Reports 50:11, pages 9663-9676.
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Dong Xu, Xingzhi Feng, Yuxin Wan, Lanlan Yang, Qianling Gao, Zihuan Yang & Chang Du. (2023) Curcumin nano-prodrug induces multi-phase cell cycle arrest in colorectal cancer through suppression of CDKs and specific down-regulation of PLK1. Smart Materials in Medicine 4, pages 648-660.
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Abigail L. Flint, David W. Hansen, LaVauria D. Brown, Laura E. Stewart, Eduardo Ortiz & Siva S. Panda. (2022) Modified Curcumins as Potential Drug Candidates for Breast Cancer: An Overview. Molecules 27:24, pages 8891.
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Yijing Zhang, Jingyi Zhu, Haitao Sun & Jingchao Li. (2022) Modulation of tumor hypoxia and redox microenvironment using nanomedicines for enhanced cancer photodynamic therapy. Applied Materials Today 29, pages 101687.
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Maria Younes, Rita Mardirossian, Liza Rizk, Tia Fazlian, Jean Paul Khairallah, Christopher Sleiman, Hassan Y. Naim & Sandra Rizk. (2022) The Synergistic Effects of Curcumin and Chemotherapeutic Drugs in Inhibiting Metastatic, Invasive and Proliferative Pathways. Plants 11:16, pages 2137.
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Maryam Safi, Habib Onsori & Mohammad Rahmati. (2022) Investigation of the Anti-Cancer Effects of Free and PLGA-PAA Encapsulated Hydroxytyrosol on the MCF-7 Breast Cancer Cell Line. Current Molecular Medicine 22:7, pages 657-662.
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Michael Flanders & William M. Gramlich. (2022) Water-Soluble and Degradation-Resistant Curcumin Copolymers from Reversible Addition–Fragmentation Chain (RAFT) Copolymerization. Macromolecules 55:10, pages 4064-4075.
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Wensen Zhang, Na Cui, Jin Ye, Bingyou Yang, Yanping Sun & Haixue Kuang. (2022) Curcumin's prevention of inflammation-driven early gastric cancer and its molecular mechanism. Chinese Herbal Medicines 14:2, pages 244-253.
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Li Xue, Yuhua Tao, Yanjuan Yuan, Wei Qu & Wei Wang. (2021) Curcumin suppresses renal carcinoma tumorigenesis by regulating circ-FNDC3B/miR-138-5p/IGF2 axis. Anti-Cancer Drugs 32:7, pages 734-744.
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Jianran Hu, Ping Li, Baozhong Shi & Jun Tie. (2021) Effects and Mechanisms of Saikosaponin D Improving the Sensitivity of Human Gastric Cancer Cells to Cisplatin. ACS Omega 6:29, pages 18745-18755.
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Keerti Mishra & Akhlesh K. Jain. (2021) Liposomes: An Emerging Approach for the Treatment of Cancer. Current Pharmaceutical Design 27:20, pages 2398-2414.
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Yong Xia, Ruijiao Chen, Guangzhen Lu, Changlin Li, Sen Lian, Taek-Won Kang & Young Do Jung. (2021) Natural Phytochemicals in Bladder Cancer Prevention and Therapy. Frontiers in Oncology 11.
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Samrajya Lakshmi Yeruva, Prashant Kumar, Seetharam Deepa & Anand K Kondapi. (2021) Lactoferrin nanoparticles coencapsulated with curcumin and tenofovir improve vaginal defense against HIV-1 infection. Nanomedicine 16:7, pages 569-586.
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Xian-ting Liang, Yan-yan Wang, Xiao-yu Hu & Shao-bo Wang. (2021) The Protective Effects of Water Extracts of Compound Turmeric Recipe on Acute Alcoholism: An Experimental Research Using a Mouse Model. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-13.
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Fei Mo, Yinan Xiao, Hao Zeng, Dian Fan, Jinen Song, Xiaobei Liu, Meng Luo & Xuelei Ma. (2021) Curcumin-Induced Global Profiling of Transcriptomes in Small Cell Lung Cancer Cells. Frontiers in Cell and Developmental Biology 8.
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Dejene Tolossa Debela, Seke GY Muzazu, Kidist Digamo Heraro, Maureen Tayamika Ndalama, Betelhiem Woldemedhin Mesele, Dagimawi Chilot Haile, Sophia Khalayi Kitui & Tsegahun Manyazewal. (2021) New approaches and procedures for cancer treatment: Current perspectives. SAGE Open Medicine 9, pages 205031212110343.
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Yun Hsuan Lin & Ching-Yi Chen. (2020) Folate-Targeted Curcumin-Encapsulated Micellar Nanosystem for Chemotherapy and Curcumin-Mediated Photodynamic Therapy. Polymers 12:10, pages 2280.
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Thimmasandra Narayan Ramesh, Manoj Paul, Kurnegala Manikanta & Kesturu S. Girish. (2020) Structure and morphological studies of curcuminoids and curcuminoid mixture. Journal of Crystal Growth 547, pages 125812.
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Hui LiWenhua XuXuying LiuJunli YePeijie LiFangfang ShangXiaoling Yu. (2020) Curcumin Alleviates the Side Effects of Cisplatin on Gastric Emptying of Mice by Inhibiting the Signal Changes of Acetylcholine and Interstitial Cells of Cajal. Journal of Medicinal Food 23:9, pages 920-927.
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Jiasheng Wu, Jie Sha, Chuangli Zhang, Weimin Liu, Xiuli Zheng & Pengfei Wang. (2020) Recent advances in theranostic agents based on natural products for photodynamic and sonodynamic therapy. View 1:3, pages 20200090.
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Dangquan Zhang & Arun Kanakkanthara. (2020) Beyond the Paclitaxel and Vinca Alkaloids: Next Generation of Plant-Derived Microtubule-Targeting Agents with Potential Anticancer Activity. Cancers 12:7, pages 1721.
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Adhimoolam Karthikeyan, Natesan Senthil & Taesun Min. (2020) Nanocurcumin: A Promising Candidate for Therapeutic Applications. Frontiers in Pharmacology 11.
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Bruna Girardi, Maria Pricci, Floriana Giorgio, Mariano Piazzolla, Andrea Iannone, Giuseppe Losurdo, Mariabeatrice Principi, Michele Barone, Enzo Ierardi & Alfredo Di Leo. (2020) Silymarin, boswellic acid and curcumin enriched dietetic formulation reduces the growth of inherited intestinal polyps in an animal model. World Journal of Gastroenterology 26:14, pages 1601-1612.
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Nurul Azwa Abd. Wahab, Nordin H. Lajis, Faridah Abas, Iekhsan Othman & Rakesh Naidu. (2020) Mechanism of Anti-Cancer Activity of Curcumin on Androgen-Dependent and Androgen-Independent Prostate Cancer. Nutrients 12:3, pages 679.
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Qiong-Qiong Yang, Arakkaveettil Kabeer Farha, Gowoon Kim, Khalid Gul, Ren-You Gan & Harold Corke. (2020) Antimicrobial and anticancer applications and related mechanisms of curcumin-mediated photodynamic treatments. Trends in Food Science & Technology 97, pages 341-354.
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Leila Dinparast, Salar Hemmati, Ali Akbar Alizadeh, Gokhan Zengin, Hossein Samadi Kafil, Mir Babak Bahadori & Siavoush Dastmalchi. (2020) An efficient, catalyst-free, one-pot synthesis of 4H-chromene derivatives and investigating their biological activities and mode of interactions using molecular docking studies. Journal of Molecular Structure 1203, pages 127426.
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Zhongtao Zhang, Ruyi Wang, Xiaoxian Huang, Renjie Luo, Jingwei Xue, Jing Gao, Wenyuan Liu, Fulei Liu, Feng Feng & Wei Qu. (2020) Self-Delivered and Self-Monitored Chemo-Photodynamic Nanoparticles with Light-Triggered Synergistic Antitumor Therapies by Downregulation of HIF-1α and Depletion of GSH. ACS Applied Materials & Interfaces 12:5, pages 5680-5694.
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Muhammad J. Iqbal, Masood S. Butt, Muhammad Sohail & Hafiz A.R. Suleria. (2020) The Antioxidant Potential of Black Cumin (Nigella sativa L.) Extracts Through Different Extraction Methods. Current Bioactive Compounds 15:6, pages 623-630.
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Iahtisham‐Ul‐Haq, Masood Sadiq Butt, Muhammad Atif Randhawa & Muhammad Shahid. (2019) Hepatoprotective effects of red beetroot‐based beverages against CCl 4 ‐induced hepatic stress in Sprague Dawley rats . Journal of Food Biochemistry 43:12.
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Arash Karimi, Ramin Ghodsi, Fateme Kooshki, Mozhdeh Karimi, Vahid Asghariazar & Ali Tarighat‐Esfanjani. (2019) Therapeutic effects of curcumin on sepsis and mechanisms of action: A systematic review of preclinical studies. Phytotherapy Research 33:11, pages 2798-2820.
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