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Research Article

Current and Potential Rodent Screens and Tests for Thyroid Toxicants

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Pages 55-95 | Published online: 10 Oct 2008

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Yin-Feng Zhang, Hai-Ming Xu, Fei Yu, Hong-Yu Yang, Dong-Dong Jia & Pei-Feng Li. (2019) Comparison the sensitivity of amphibian metamorphosis assays with NF 48 stage and NF 51 stage Xenopus laevis tadpoles. Toxicology Mechanisms and Methods 29:6, pages 421-427.
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Virunya S. Bhat, Jennifer L. Durham, Gwendolyn L. Ball & J. Caroline English. (2014) Derivation of an Oral Reference Dose (RfD) for the Nonphthalate Alternative Plasticizer 1,2-Cyclohexane Dicarboxylic Acid, Di-Isononyl Ester (DINCH). Journal of Toxicology and Environmental Health, Part B 17:2, pages 63-94.
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R. Thomas Zoeller & Shirlee W. Tan. (2007) Implications of Research on Assays to Characterize Thyroid Toxicants. Critical Reviews in Toxicology 37:1-2, pages 195-210.
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F. M. Anne McNabb. (2007) The Hypothalamic-Pituitary-Thyroid (HPT) Axis in Birds and Its Role in Bird Development and Reproduction. Critical Reviews in Toxicology 37:1-2, pages 163-193.
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Shirlee W. Tan, Gary E. Timm & Patric Amcoff. (2007) History and Genesis of the Detailed Review of Thyroid Hormone Disruption Assays. Critical Reviews in Toxicology 37:1-2, pages 1-4.
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Valentina Guarnotta, Roberta Amodei, Francesco Frasca, Antonio Aversa & Carla Giordano. (2022) Impact of Chemical Endocrine Disruptors and Hormone Modulators on the Endocrine System. International Journal of Molecular Sciences 23:10, pages 5710.
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Shengnan Zhang, Xiaochun Guo, Shaoyong Lu, Jia He, Qin Wu, Xiaohui Liu, Zhenyang Han & Ping Xie. (2022) Perfluorohexanoic acid caused disruption of the hypothalamus-pituitary-thyroid axis in zebrafish larvae. Ecotoxicology and Environmental Safety 232, pages 113283.
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Jinbo Li, Yuanyuan Li, Min Zhu, Shilin Song & Zhanfen Qin. (2022) A Multiwell-Based Assay for Screening Thyroid Hormone Signaling Disruptors Using thibz Expression as a Sensitive Endpoint in Xenopus laevis. Molecules 27:3, pages 798.
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Jiefeng Tan, Hongxing Chen, Shanduo Chen, Junjie Hu, Xiaolan Wang, Yifan Wang, Shuling Liao, Peixian Chen, Chuyan Liang, Menglin Dai, Qianping Du & Liping Hou. (2022) The interactive effects of ethinylestradiol and progesterone on transcriptional expression of genes along the hypothalamus–pituitary–thyroid axis in embryonic zebrafish (Danio rerio). Science of The Total Environment 805, pages 150371.
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Fengxiao Hu, Yixin Zhao, Yuan Yuan, Li Yin, Feilong Dong, Weini Zhang & Xinhua Chen. (2021) Effects of environmentally relevant concentrations of tris (2-chloroethyl) phosphate (TCEP) on early life stages of zebrafish (Danio rerio). Environmental Toxicology and Pharmacology 83, pages 103600.
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Parth Pandya, Pragna Parikh & Ankita Ambegaonkar. (2020) Evaluating the toxic potential of agrochemicals on the hypothalamic‐pituitary‐thyroid axis in tilapia (Oreochromis mossambicus) . Journal of Applied Ichthyology 36:2, pages 203-211.
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Luyin Wu, Huijun Ru, Zhaohui Ni, Xiaoxin Zhang, Huaxiao Xie, Fan Yao, He Zhang, Yunfeng Li & Liqiao Zhong. (2019) Comparative thyroid disruption by o,p’-DDT and p,p’-DDE in zebrafish embryos/larvae. Aquatic Toxicology 216, pages 105280.
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Ruediger Bartsch, Britta Brinkmann, Gunnar Jahnke, Britta Laube, Ruth Lohmann, Sandra Michaelsen, Ingrid Neumann & Helmut Greim. (2018) Human relevance of follicular thyroid tumors in rodents caused by non-genotoxic substances. Regulatory Toxicology and Pharmacology 98, pages 199-208.
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Oddvar Myhre, Marit Låg, Gro D. Villanger, Bente Oftedal, Johan Øvrevik, Jørn A. Holme, Heidi Aase, Ragnhild E. Paulsen, Anna Bal-Price & Hubert Dirven. (2018) Early life exposure to air pollution particulate matter (PM) as risk factor for attention deficit/hyperactivity disorder (ADHD): Need for novel strategies for mechanisms and causalities. Toxicology and Applied Pharmacology 354, pages 196-214.
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Yaling Sun, Yingwen Li, Zhihao Liu & Qiliang Chen. (2018) Environmentally relevant concentrations of mercury exposure alter thyroid hormone levels and gene expression in the hypothalamic–pituitary–thyroid axis of zebrafish larvae. Fish Physiology and Biochemistry 44:4, pages 1175-1183.
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Shengnan Zhang, Xiaochun Guo, Shaoyong Lu, Nan Sang, Guangyu Li, Ping Xie, Chunsheng Liu, Liguo Zhang & Yi Xing. (2018) Exposure to PFDoA causes disruption of the hypothalamus-pituitary-thyroid axis in zebrafish larvae. Environmental Pollution 235, pages 974-982.
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Larry P. Sheets & William SlikkerJr.Jr.. 2018. Handbook of Developmental Neurotoxicology. Handbook of Developmental Neurotoxicology 527 538 .
A. C. GoreV. A. ChappellS. E. FentonJ. A. FlawsA. NadalG. S. PrinsJ. ToppariR. T. Zoeller. (2015) EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals. Endocrine Reviews 36:6, pages E1-E150.
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Tianle Tang, Yang Yang, Yawen Chen, Wenhao Tang, Fuqiang Wang & Xiaoping Diao. (2015) Thyroid Disruption in Zebrafish Larvae by Short-Term Exposure to Bisphenol AF. International Journal of Environmental Research and Public Health 12:10, pages 13069-13084.
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Yinfeng Zhang, Yuanyuan Li, Zhanfen Qin, Huili Wang & Jianzhong Li. (2015) A screening assay for thyroid hormone signaling disruption based on thyroid hormone-response gene expression analysis in the frog Pelophylax nigromaculatus. Journal of Environmental Sciences 34, pages 143-154.
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Yan-Qiu Liang, Guo-Yong Huang, Guang-Guo Ying, Shuang-Shuang Liu, Yu-Xia Jiang & Shan Liu. (2015) Progesterone and norgestrel alter transcriptional expression of genes along the hypothalamic–pituitary–thyroid axis in zebrafish embryos-larvae. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 167, pages 101-107.
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David S. Sharlin. 2015. Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders. Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders 167 192 .
Katie B. Paul, Joan M. Hedge, Chitralekha Macherla, Dayne L. Filer, Emily Burgess, Steven O. Simmons, Kevin M. Crofton & Michael W. Hornung. (2013) Cross-species analysis of thyroperoxidase inhibition by xenobiotics demonstrates conservation of response between pig and rat. Toxicology 312, pages 97-107.
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R. Thomas Zoeller, T. R. Brown, L. L. Doan, A. C. Gore, N. E. Skakkebaek, A. M. Soto, T. J. Woodruff & F. S. Vom Saal. (2012) Endocrine-Disrupting Chemicals and Public Health Protection: A Statement of Principles from The Endocrine Society. Endocrinology 153:9, pages 4097-4110.
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Demetrio Raldúa, Benedicte Thienpont & Patrick J. Babin. (2012) Zebrafish eleutheroembryos as an alternative system for screening chemicals disrupting the mammalian thyroid gland morphogenesis and function. Reproductive Toxicology 33:2, pages 188-197.
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Joseph G. Schnitzler, Niko Celis, Peter H.M. Klaren, Ronny Blust, Alin C. Dirtu, Adrian Covaci & Krishna Das. (2011) Thyroid dysfunction in sea bass (Dicentrarchus labrax): Underlying mechanisms and effects of polychlorinated biphenyls on thyroid hormone physiology and metabolism. Aquatic Toxicology 105:3-4, pages 438-447.
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Gro D. Villanger, Bjørn M. Jenssen, Rita R. Fjeldberg, Robert J. Letcher, Derek C.G. Muir, Maja Kirkegaard, Christian Sonne & Rune Dietz. (2011) Exposure to mixtures of organohalogen contaminants and associative interactions with thyroid hormones in East Greenland polar bears (Ursus maritimus). Environment International 37:4, pages 694-708.
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Liqin Yu, Jun Deng, Xiongjie Shi, Chunsheng Liu, Ke Yu & Bingsheng Zhou. (2010) Exposure to DE-71 alters thyroid hormone levels and gene transcription in the hypothalamic–pituitary–thyroid axis of zebrafish larvae. Aquatic Toxicology 97:3, pages 226-233.
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Mark D. Miller, Kevin M. Crofton, Deborah C. Rice & R. Thomas Zoeller. (2009) Thyroid-Disrupting Chemicals: Interpreting Upstream Biomarkers of Adverse Outcomes. Environmental Health Perspectives 117:7, pages 1033-1041.
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Simona De Angelis, Roberta Tassinari, Francesca Maranghi, Agostino Eusepi, Antonio Di Virgilio, Flavia Chiarotti, Laura Ricceri, Aldina Venerosi Pesciolini, Enzo Gilardi, Gabriele Moracci, Gemma Calamandrei, Antonella Olivieri & Alberto Mantovani. (2009) Developmental Exposure to Chlorpyrifos Induces Alterations in Thyroid and Thyroid Hormone Levels Without Other Toxicity Signs in Cd1 Mice. Toxicological Sciences 108:2, pages 311-319.
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Guillaume Pelletier, Sheila Masson, Mike J. Wade, Jamie Nakai, Ramona Alwis, Susantha Mohottalage, Premkumari Kumarathasan, Paleah Black, Wayne J. Bowers, Ih Chu & Renaud Vincent. (2009) Contribution of methylmercury, polychlorinated biphenyls and organochlorine pesticides to the toxicity of a contaminant mixture based on Canadian Arctic population blood profiles. Toxicology Letters 184:3, pages 176-185.
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