226
Views
38
CrossRef citations to date
0
Altmetric
Research Article

Apoptotic Cell Death Induced by Low-Dose Radiation in Male Germ Cells: Hormesis and Adaptation

, , , , &
Pages 587-605 | Published online: 10 Oct 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Victor Udo Nna, Ainul Bahiyah Abu Bakar, Azlina Ahmad & Mahaneem Mohamed. (2020) Diabetes-induced testicular oxidative stress, inflammation, and caspase-dependent apoptosis: the protective role of metformin. Archives of Physiology and Biochemistry 126:5, pages 377-388.
Read now
Sema Yilmaz Rakici, Ali Irfan Guzel, Levent Tumkaya, Hatice Sevim Nalkiran & Tolga Mercantepe. (2020) Pelvic Radiation-Induced Testicular Damage: An Experimental Study at 1 Gray. Systems Biology in Reproductive Medicine 66:2, pages 89-98.
Read now
Yuguang Zhao, Hongguang Zhao, Xujie Zhai, Junying Dai, Xin Jiang, Guanjun Wang, Wei Li & Lu Cai. (2013) Effects of Zn deficiency, antioxidants, and low-dose radiation on diabetic oxidative damage and cell death in the testis. Toxicology Mechanisms and Methods 23:1, pages 42-47.
Read now

Articles from other publishers (35)

Dietrich Averbeck & Claire Rodriguez-Lafrasse. (2021) Role of Mitochondria in Radiation Responses: Epigenetic, Metabolic, and Signaling Impacts. International Journal of Molecular Sciences 22:20, pages 11047.
Crossref
Hongyan Li, Weihong Zhang, Hong Zhang, Yi Xie, Chao Sun, Cuixia Di, Jing Si, Lu Gan & Junfang Yan. (2019) Mitochondrial proteomics reveals the mechanism of spermatogenic cells apoptosis induced by carbon ion radiation in zebrafish. Journal of Cellular Physiology 234:12, pages 22439-22449.
Crossref
Victor Udo Nna, Ainul Bahiyah Abu Bakar, Azlina Ahmad, Chinedum Ogbonnaya Eleazu & Mahaneem Mohamed. (2019) Oxidative Stress, NF-κB-Mediated Inflammation and Apoptosis in the Testes of Streptozotocin–Induced Diabetic Rats: Combined Protective Effects of Malaysian Propolis and Metformin. Antioxidants 8:10, pages 465.
Crossref
Rana Keyhanmanesh, Gholamreza Hamidian, Mohammad Reza Alipour & Hajar Oghbaei. (2019) Beneficial treatment effects of dietary nitrate supplementation on testicular injury in streptozotocin-induced diabetic male rats. Reproductive BioMedicine Online 39:3, pages 357-371.
Crossref
Junling Zhang, Dan Yao, Jianghong Zhang, Yimeng Song, Fang Mo, Xiaofei Chu, Yan Pan, Yang Bai & Chunlin Shao. (2019) TGF-β mediates thoracic radiation-induced abscopal effects of testis injury in rat. Biochemical and Biophysical Research Communications 514:3, pages 678-683.
Crossref
Bobby R. Scott & Sujeenthar Tharmalingam. (2019) The LNT model for cancer induction is not supported by radiobiological data. Chemico-Biological Interactions 301, pages 34-53.
Crossref
Kaihua Ji, Yan Wang, Liqing Du, Chang Xu, Yang Liu, Ningning He, Jinhan Wang & Qiang Liu. (2019) Research Progress on the Biological Effects of Low-Dose Radiation in China. Dose-Response 17:1, pages 155932581983348.
Crossref
Witawat Jangiam, Chatchanok Udomtanakunchai, Paiboon Reungpatthanaphong, Montree Tungjai, Louise Honikel, Chris R. Gordon & Kanokporn Noy Rithidech. (2018) Late Effects of Low-Dose Radiation on the Bone Marrow, Lung, and Testis Collected From the Same Exposed BALB/cJ Mice. Dose-Response 16:4, pages 155932581881503.
Crossref
Katherine E. Chapman, George R. Hoffmann, Shareen H. Doak & Gareth J.S. Jenkins. (2017) Investigation of J-shaped dose-responses induced by exposure to the alkylating agent N -methyl- N -nitrosourea. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 819, pages 38-46.
Crossref
M. Al. Meselmani, M. M. Bakuev, R. K. Shakhbanov & T. M. Dibirov. (2017) The impact of single external γ-irradiation on morphology of rat testis. Problemy reproduktsii 23:6, pages 12.
Crossref
Fangfang Zhang, Xiufei Lin, Lechu Yu, Weihua Li, Dingliang Qian, Peng Cheng, Luqing He, Hong Yang & Chi Zhang. (2016) Low‐dose radiation prevents type 1 diabetes‐induced cardiomyopathy via activation of AKT mediated anti‐apoptotic and anti‐oxidant effects . Journal of Cellular and Molecular Medicine 20:7, pages 1352-1366.
Crossref
Yuguang Zhao, Chuipeng Kong, Xiao Chen, Zhenyu Wang, Zhiqiang Wan, Lin Jia, Qiuju Liu, Yuehui Wang, Wei Li, Jiuwei Cui, Fujun Han & Lu Cai. (2016) Repetitive exposure to low-dose X-irradiation attenuates testicular apoptosis in type 2 diabetic rats, likely via Akt-mediated Nrf2 activation. Molecular and Cellular Endocrinology 422, pages 203-210.
Crossref
Minglong ShaoLechu YuFangfang ZhangXuemian LuXiaokun LiPeng ChengXiufei LinLuqing HeShunzi Jin, Yi Tan, Hong YangChi ZhangLu Cai. (2015) Additive protection by LDR and FGF21 treatment against diabetic nephropathy in type 2 diabetes model. American Journal of Physiology-Endocrinology and Metabolism 309:1, pages E45-E54.
Crossref
V. A. Tronov, Yu. V. Vinogradova, V. A. Poplinskaya, E. I. Nekrasova & M. A. Ostrovskii. (2015) Radiation preconditioning in vivo increases the resistance of mouse retina to genotoxic exposure and stimulates its regeneration. Cell and Tissue Biology 9:3, pages 198-207.
Crossref
V. Seco-Rovira, E. Beltrán-Frutos, C. Ferrer, F. J. Saez, J. F. Madrid, M. Canteras & L. M. Pastor. (2015) Testicular histomorphometry and the proliferative and apoptotic activities of the seminiferous epithelium in Syrian hamster ( Mesocricetus auratus ) during regression owing to short photoperiod . Andrology 3:3, pages 598-610.
Crossref
Natasha R. Catlin, Susan M. Huse & Kim Boekelheide. (2014) The Stage-specific Testicular Germ Cell Apoptotic Response to Low-dose Radiation and 2,5-hexanedione Combined Exposure. II. Toxicologic Pathology 42:8, pages 1229-1237.
Crossref
Melissa Skibba, Chi Zhang, Xin Jiang, Ying Xin & Lu Cai. (2014) Preventive effect of non-mitogenic acidic fibroblast growth factor on diabetes-induced testicular cell death. Reproductive Toxicology 49, pages 136-144.
Crossref
Minglong Shao, Xuemian Lu, Weitao Cong, Xiao Xing, Yi Tan, Yunqian Li, Xiaokun Li, Litai Jin, Xiaojie Wang, Juancong Dong, Shunzi Jin, Chi Zhang & Lu Cai. (2014) Multiple Low-Dose Radiation Prevents Type 2 Diabetes-Induced Renal Damage through Attenuation of Dyslipidemia and Insulin Resistance and Subsequent Renal Inflammation and Oxidative Stress. PLoS ONE 9:3, pages e92574.
Crossref
Hideaki Yamashiro, Yasuyuki Abe, Tomokazu Fukuda, Yasushi Kino, Isao Kawaguchi, Yoshikazu Kuwahara, Motoi Fukumoto, Shintaro Takahashi, Masatoshi Suzuki, Jin Kobayashi, Emi Uematsu, Bin Tong, Takahisa Yamada, Satoshi Yoshida, Eimei Sato, Hisashi Shinoda, Tsutomu Sekine, Emiko Isogai & Manabu Fukumoto. (2013) Effects of radioactive caesium on bull testes after the Fukushima nuclear plant accident. Scientific Reports 3:1.
Crossref
Zhi-cheng Wang, Jian-feng Wang, Yan-bo Li, Cai-xia Guo, Yang Liu, Fang Fang & Shou-liang Gong. (2013) Involvement of endoplasmic reticulum stress in apoptosis of testicular cells induced by low-dose radiation. Journal of Huazhong University of Science and Technology [Medical Sciences] 33:4, pages 551-558.
Crossref
Wu-Gang Hou, Jie Zhao, Zhen Li, Wei Li, Teng Li, Li-Ze Xiong & Yuan-Qiang Zhang. (2012) Effects of Electromagnetic Pulse Irradiation on the Mouse Blood-testicle Barrier. Urology 80:1, pages 225.e1-225.e6.
Crossref
G. L. Russo, I. Tedesco, M. Russo, A. Cioppa, M. G. Andreassi & E. Picano. (2011) Cellular adaptive response to chronic radiation exposure in interventional cardiologists. European Heart Journal 33:3, pages 408-414.
Crossref
Kanokporn Noy Rithidech, Xianyin Lai, Louise Honikel, Paiboon Reungpatthanaphong & Frank A. Witzmann. (2012) IDENTIFICATION OF PROTEINS SECRETED INTO THE MEDIUM BY HUMAN LYMPHOCYTES IRRADIATED IN VITRO WITH OR WITHOUT ADAPTIVE ENVIRONMENTS. Health Physics 102:1, pages 39-53.
Crossref
Chi Zhang, Shunzi Jin, Weiying Guo, Cai Li, Xiaokun Li, Madhavi J. Rane, Guanjun Wang & Lu Cai. (2011) Attenuation of Diabetes-Induced Cardiac Inflammation and Pathological Remodeling by Low-Dose Radiation. Radiation Research 175:3, pages 307-321.
Crossref
LM Pastor, A Zuasti, C Ferrer, CM Bernal‐Mañas, E Morales, E Beltrán‐Frutos & V Seco‐Rovira. (2011) Proliferation and Apoptosis in Aged and Photoregressed Mammalian Seminiferous Epithelium, with Particular Attention to Rodents and Humans. Reproduction in Domestic Animals 46:1, pages 155-164.
Crossref
Yuguang Zhao, Yi Tan, Junying Dai, Bing Li, Luping Guo, Jiuwei Cui, Guanjun Wang, Xue Shi, Xiang Zhang, Nicholas Mellen, Wei Li & Lu Cai. (2011) Exacerbation of diabetes-induced testicular apoptosis by zinc deficiency is most likely associated with oxidative stress, p38 MAPK activation, and p53 activation in mice. Toxicology Letters 200:1-2, pages 100-106.
Crossref
Wei-Ying Guo, Guan-Jun Wang, Ping Wang, Qiang Chen, Yi Tan & Lu Cai. (2010) Acceleration of Diabetic Wound Healing by Low-Dose Radiation is Associated with Peripheral Mobilization of Bone Marrow Stem Cells. Radiation Research 174:4, pages 467-479.
Crossref
Chi Zhang, Xiaokun Li & Lu Cai. (2010) Reply to “Letter to the Editor: ‘Low-dose whole body irradiation: a potential therapeutic modality’”. American Journal of Physiology-Endocrinology and Metabolism 299:1, pages E138-E140.
Crossref
Hongguang Zhao, Songbai Xu, Zhicheng Wang, Yanbo Li, Wei Guo, Chenghe Lin, Shouliang Gong, Cai Li, Guanjun Wang & Lu Cai. (2010) Repetitive exposures to low-dose X-rays attenuate testicular apoptotic cell death in streptozotocin-induced diabetes rats. Toxicology Letters 192:3, pages 356-364.
Crossref
Paula Toni Del Giudice, Samira Barbosa Lima, Marcos Antonio Cenedeze, Álvaro Pacheco-Silva, Ricardo Pimenta Bertolla & Agnaldo Pereira Cedenho. (2010) Expression of the Fas-ligand gene in ejaculated sperm from adolescents with and without varicocele. Journal of Assisted Reproduction and Genetics 27:2-3, pages 103-109.
Crossref
Chi ZhangYi TanWeiying GuoCai LiShunzi JiXiaokun Li & Lu Cai. (2009) Attenuation of diabetes-induced renal dysfunction by multiple exposures to low-dose radiation is associated with the suppression of systemic and renal inflammation. American Journal of Physiology-Endocrinology and Metabolism 297:6, pages E1366-E1377.
Crossref
A. Hassan, E. M. El-Nashar & T. Mostafa. (2009) Programmed cell death in varicocele-bearing testes. Andrologia 41:1, pages 39-45.
Crossref
M.-J. Guerquin, C. Duquenne, H. Coffigny, V. Rouiller-Fabre, R. Lambrot, M. Bakalska, R. Frydman, R. Habert & G. Livera. (2008) Sex-specific differences in fetal germ cell apoptosis induced by ionizing radiation. Human Reproduction 24:3, pages 670-678.
Crossref
D.M. Nejad, J.S. Rad, L. Roshankar, M. Karimipor, A.A. Ghanbari, A. Aazami & M.R. Valilou. (2008) A Study on the Effect of Thiotepa on Mice SpermatogenesisUsing Light and Electronic Microscope. Pakistan Journal of Biological Sciences 11:15, pages 1929-1934.
Crossref
Marina Zemskova, Eva Sahakian, Svetlana Bashkirova & Michael Lilly. (2008) The PIM1 Kinase Is a Critical Component of a Survival Pathway Activated by Docetaxel and Promotes Survival of Docetaxel-treated Prostate Cancer Cells. Journal of Biological Chemistry 283:30, pages 20635-20644.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.