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Research Article

Immunotoxicity of Perfluorooctanoic Acid and Perfluorooctane Sulfonate and the Role of Peroxisome Proliferator-Activated Receptor Alpha

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Pages 76-94 | Published online: 08 Jan 2009

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Rachel P. Frawley, Matthew Smith, Mark F. Cesta, Schantel Hayes-Bouknight, Chad Blystone, Grace E. Kissling, Shawn Harris & Dori Germolec. (2018) Immunotoxic and hepatotoxic effects of perfluoro-n-decanoic acid (PFDA) on female Harlan Sprague–Dawley rats and B6C3F1/N mice when administered by oral gavage for 28 days. Journal of Immunotoxicology 15:1, pages 41-52.
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Ellen T. Chang, Hans-Olov Adami, Paolo Boffetta, H. James Wedner & Jack S. Mandel. (2016) A critical review of perfluorooctanoate and perfluorooctanesulfonate exposure and immunological health conditions in humans. Critical Reviews in Toxicology 46:4, pages 279-331.
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Qixiao Jiang, Robert M. Lust & Jamie C. DeWitt. (2013) Perfluorooctanoic Acid Induced-Developmental Cardiotoxicity: Are Peroxisome Proliferator Activated Receptor α (PPARα) and Bone Morphorgenic Protein 2 (BMP2) Pathways Involved?. Journal of Toxicology and Environmental Health, Part A 76:11, pages 635-650.
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Jennifer Franko, B. J. Meade, H. Frederick Frasch, Ana M. Barbero & Stacey E. Anderson. (2012) Dermal Penetration Potential of Perfluorooctanoic Acid (PFOA) in Human and Mouse Skin. Journal of Toxicology and Environmental Health, Part A 75:1, pages 50-62.
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Patricia A. Fair, Erin Driscoll, Meagan A. M. Mollenhauer, Sarah G. Bradshaw, Se Hun Yun, Kurunthachalam Kannan, Gregory D. Bossart, Deborah E. Keil & Margie M. Peden-Adams. (2011) Effects of environmentally-relevant levels of perfluorooctane sulfonate on clinical parameters and immunological functions in B6C3F1 mice. Journal of Immunotoxicology 8:1, pages 17-29.
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MeaganA.M. Mollenhauer, SarahG. Bradshaw, PatriciaA. Fair, W. David McGuinn & MargieM. Peden-Adams. (2011) Effects of perfluorooctane sulfonate (PFOS) exposure on markers of inflammation in female B6C3F1 mice. Journal of Environmental Science and Health, Part A 46:2, pages 97-108.
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Yong Qian, Alan Ducatman, Rebecca Ward, Steve Leonard, Valerie Bukowski, Nancy Lan Guo, Xianglin Shi, Val Vallyathan & Vincent Castranova. (2010) Perfluorooctane Sulfonate (PFOS) Induces Reactive Oxygen Species (ROS) Production in Human Microvascular Endothelial Cells: Role in Endothelial Permeability. Journal of Toxicology and Environmental Health, Part A 73:12, pages 819-836.
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