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Critical Reviews in Toxicology Volume 50, 2020 - Issue 9
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Review Articles

Towards a mechanism-based approach for the prediction of nongenotoxic carcinogenic potential of agrochemicals

Harm Heusinkvelda Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, the NetherlandsCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-3269-5586
ORCID Icon,
Hedwig Braakhuisa Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands
,
Robin Gommansa Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands
,
Phil Bothamb Syngenta Crop Protection, Bracknell, UK;
,
Marco Corvaroc Corteva Agriscience, Rome, ItalyORCID Iconhttps://orcid.org/0000-0002-3215-9820
ORCID Icon,
Jan Willem van der Laand Medicines Evaluation Board, Utrecht, the NetherlandsORCID Iconhttps://orcid.org/0000-0003-2963-6136
ORCID Icon,
Dick Lewisb Syngenta Crop Protection, Bracknell, UK;
,
Federica Madiae European Commission, Joint Research Centre (JRC), Ispra, ItalyORCID Iconhttps://orcid.org/0000-0002-8438-0957
ORCID Icon,
Irene Manouf European Partnership for Alternative Approaches to Animal Testing (EPAA), Brussels, Belgium
,
Frédéric Schorschg Bayer SAS, Lyon, France;
,
Gerrit Wolterinkh Centre for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment (RIVM), Bilthoven, the NetherlandsORCID Iconhttps://orcid.org/0000-0001-8825-984X
ORCID Icon,
Ruud Wouterseni TNO Quality of Life, Zeist, and Wageningen University & Research, Wageningen, the Netherlands
,
Raffaella Corvie European Commission, Joint Research Centre (JRC), Ispra, Italy
,
Jyotigna Mehtaj ADAMA Agricultural Solutions Ltd, Reading, UKORCID Iconhttps://orcid.org/0000-0002-4705-0158
ORCID Icon &
Mirjam Luijtena Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, the NetherlandsORCID Iconhttps://orcid.org/0000-0002-5277-1443
ORCID Icon show all
Pages 725-739 | Received 02 Jul 2020, Accepted 21 Oct 2020, Published online: 25 Nov 2020

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Tomoya Yamada, Brian G. Lake & Samuel M. Cohen. (2022) Evaluation of the human hazard of the liver and lung tumors in mice treated with permethrin based on mode of action. Critical Reviews in Toxicology 52:1, pages 1-31.
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Susan P. Felter, Virunya S. Bhat, Philip A. Botham, David A. Bussard, Warren Casey, A. Wallace Hayes, Gina M. Hilton, Kelly A. Magurany, Ursula G. Sauer & Edward V. Ohanian. (2021) Assessing chemical carcinogenicity: hazard identification, classification, and risk assessment. Insight from a Toxicology Forum state-of-the-science workshop. Critical Reviews in Toxicology 51:8, pages 653-694.
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Tomoya Yamada, Samuel M. Cohen & Brian G. Lake. (2021) Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR). Critical Reviews in Toxicology 51:5, pages 373-394.
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