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Research Article

Xenobiotic-Metabolizing Cytochrome P450 Enzymes in the Human Feto-Placental Unit: Role in Intrauterine Toxicity

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Pages 35-72 | Published online: 29 Sep 2008

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Ji Soo Lee, Roberto Romero, Yu Mi Han, Hee Chan Kim, Chong Jai Kim, Joon-Seok Hong & Dongeun Huh. (2016) Placenta-on-a-chip: a novel platform to study the biology of the human placenta. The Journal of Maternal-Fetal & Neonatal Medicine 29:7, pages 1046-1054.
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Constantinos Giaginis, Stamatios Theocharis & Anna Tsantili-Kakoulidou. (2012) Current toxicological aspects on drug and chemical transport and metabolism across the human placental barrier. Expert Opinion on Drug Metabolism & Toxicology 8:10, pages 1263-1275.
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Janne Hukkanen. (2012) Induction of cytochrome P450 enzymes: a view on human in vivo findings. Expert Review of Clinical Pharmacology 5:5, pages 569-585.
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Shakil Ahmed Saghir, Sarosh Ahmed Khan & Alene Theresa McCoy. (2012) Ontogeny of mammalian metabolizing enzymes in humans and animals used in toxicological studies. Critical Reviews in Toxicology 42:5, pages 323-357.
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Katalin Monostory, Jean-Marc Pascussi, László Kóbori & Zdenek Dvorak. (2009) Hormonal regulation of CYP1A expression. Drug Metabolism Reviews 41:4, pages 547-572.
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Jos V Castell, Ramiro Jover, Celia P Martnez-Jimnez & Mara Jos Gmez-Lechn. (2006) Hepatocyte cell lines: their use, scope and limitations in drug metabolism studies. Expert Opinion on Drug Metabolism & Toxicology 2:2, pages 183-212.
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M Strolin Benedetti, R Whomsley & E L Baltes. (2005) Differences in absorption, distribution, metabolism and excretion of xenobiotics between the paediatric and adult populations. Expert Opinion on Drug Metabolism & Toxicology 1:3, pages 447-471.
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K. Gross-Steinmeyer, P. L. Stapleton, J. H. Tracy, T. K. Bammler, T. Lehman, S. C. Strom & D. L. Eaton. (2005) Influence of Matrigel-overlay on constitutive and inducible expression of nine genes encoding drug-metabolizing enzymes in primary human hepatocytes. Xenobiotica 35:5, pages 419-438.
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Anna Makri, Michelle Goveia, John Balbus & Rebecca Parkin. (2004) CHILDREN's SUSCEPTIBILITY TO CHEMICALS: A REVIEW BY DEVELOPMENTAL STAGE. Journal of Toxicology and Environmental Health, Part B 7:6, pages 417-435.
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James B. Knaak, Curt C. Dary, Fred Power, Carol B. Thompson & Jerry N. Blancato. (2004) Physicochemical and Biological Data for the Development of Predictive Organophosphorus Pesticide QSARs and PBPK/PD Models for Human Risk Assessment. Critical Reviews in Toxicology 34:2, pages 143-207.
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J. W. Rodriguez, M. J. Kohan, L. C. King & W. G. Kirlin. (2002) DETECTION OF DNA ADDUCTS IN DEVELOPING CD4+CD8+ THYMOCYTES AND SPLENOCYTES FOLLOWING IN UTERO EXPOSURE TO BENZO[a]PYRENE. Immunopharmacology and Immunotoxicology 24:3, pages 365-381.
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Slobodan Rendic. (2002) Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metabolism Reviews 34:1-2, pages 83-448.
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Daria Pereg, Jean Lagueux, Éric Dewailly, Guy G. Poirier & Pierre Ayotte. (2001) Cigarette smoking during pregnancy: comparison of biomarkers for inclusion in epidemiological studies. Biomarkers 6:2, pages 161-173.
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Daniel Sinnett, Maja Krajinovic & Damian Labuda. (2000) Genetic Susceptibility to Childhood Acute Lymphoblastic Leukemia. Leukemia & Lymphoma 38:5-6, pages 447-462.
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