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Research Article

Ku Autoantigen: A Multifunctional DNA-Binding Protein

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Pages 1-33 | Published online: 29 Sep 2008

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Read on this site (9)

Kevin W. Trotter, Heather A. King & Trevor K. Archer. (2015) Glucocorticoid Receptor Transcriptional Activation via the BRG1-Dependent Recruitment of TOP2β and Ku70/86. Molecular and Cellular Biology 35:16, pages 2799-2817.
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Gloria C. Li, Fuqiu He & C. Clifton Ling. (2006) Hyperthermia and gene therapy: Potential use of MicroPET imaging. International Journal of Hyperthermia 22:3, pages 215-221.
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Laurent Miccoli, Isabelle Frouin, Olivia Novac, Domenic Di Paola, Francis Harper, Maria Zannis-Hadjopoulos, Giovanni Maga, Denis S. F. Biard & Jaime F. Angulo. (2005) The Human Stress-Activated Protein kin17 Belongs to the Multiprotein DNA Replication Complex and Associates In Vivo with Mammalian Replication Origins. Molecular and Cellular Biology 25:9, pages 3814-3830.
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Carsten Müller-Tidow, Ping Ji, Sven Diederichs, Jenny Potratz, Nicole Bäumer, Gabriele Köhler, Thomas Cauvet, Chunaram Choudary, Tiffany van der Meer, Wan-Yu Iris Chan, Conrad Nieduszynski, William H. Colledge, Mark Carrington, H. Phillip Koeffler, Anja Restle, Lisa Wiesmüller, Joëlle Sobczak-Thépot, Wolfgang E. Berdel & Hubert Serve. (2004) The Cyclin A1-CDK2 Complex Regulates DNA Double-Strand Break Repair. Molecular and Cellular Biology 24:20, pages 8917-8928.
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Carmen C. Sucharov, Steve M. Helmke, Stephen J. Langer, M. Benjamin Perryman, Michael Bristow & Leslie Leinwand. (2004) The Ku Protein Complex Interacts with YY1, Is Up-Regulated in Human Heart Failure, and Represses α Myosin Heavy-Chain Gene Expression. Molecular and Cellular Biology 24:19, pages 8705-8715.
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Kyungjae Myung, Goutam Ghosh, Farjana J. Fattah, Gang Li, Haeyoung Kim, Amalia Dutia, Evgenia Pak, Stephanie Smith & Eric A. Hendrickson. (2004) Regulation of Telomere Length and Suppression of Genomic Instability in Human Somatic Cells by Ku86. Molecular and Cellular Biology 24:11, pages 5050-5059.
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Jianhua Yu, Kelly Marshall, Miyuki Yamaguchi, James E. Haber & Clifford F. Weil. (2004) Microhomology-Dependent End Joining and Repair of Transposon-Induced DNA Hairpins by Host Factors in Saccharomyces cerevisiae. Molecular and Cellular Biology 24:3, pages 1351-1364.
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Yun Sok Lee, Hae‐Young Koh, Sang Dai Park & Jae Bum Kim. (2004) Identification of Ku70/Ku80 as ADD1/SREBP1c interacting proteins. Korean Journal of Biological Sciences 8:1, pages 49-55.
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Narendra Tuteja. (2000) Plant Cell and Viral Helicases: Essential Enzymes for Nucleic Acid Transactions. Critical Reviews in Plant Sciences 19:5, pages 449-478.
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Mark L. Gonzalgo & Alan Keith Meeker. 2012. Campbell-Walsh Urology. Campbell-Walsh Urology 530 567.e16 .
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Manabu Koike, Yasutomo Yutoku & Aki Koike. (2011) KARP-1 works as a heterodimer with Ku70, but the function of KARP-1 cannot perfectly replace that of Ku80 in DSB repair. Experimental Cell Research 317:16, pages 2267-2275.
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Alice Tianbu Zhang, Alexander R. Langley, Christo P. Christov, Eyemen Kheir, Thomas Shafee, Timothy J. Gardiner & Torsten Krude. (2011) Dynamic interaction of Y RNAs with chromatin and initiation proteins during human DNA replication. Journal of Cell Science 124:12, pages 2058-2069.
Crossref
Yingfeng Zheng, Zhujun Ao, Binchen Wang, Kallesh Danappa Jayappa & Xiaojian Yao. (2011) Host Protein Ku70 Binds and Protects HIV-1 Integrase from Proteasomal Degradation and Is Required for HIV Replication. Journal of Biological Chemistry 286:20, pages 17722-17735.
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C.-C. Chen, Y.-C. Yang, W.-H. Wang, C.-S. Chen & L.-K. Chang. (2010) Enhancement of Zta-activated lytic transcription of Epstein-Barr virus by Ku80. Journal of General Virology 92:3, pages 661-668.
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Ankita Shahi, Jung-Hee Lee, Yoonsung Kang, Sung Haeng Lee, Jin-Won Hyun, In-Youb Chang, Jae-Yeoul Jun & Ho Jin You. (2011) Mismatch-repair protein MSH6 is associated with Ku70 and regulates DNA double-strand break repair. Nucleic Acids Research 39:6, pages 2130-2143.
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David C. Zappulla, Karen J. Goodrich, Julian R. Arthur, Lisa A. Gurski, Elizabeth M. Denham, Anne E. Stellwagen & Thomas R. Cech. (2011) Ku can contribute to telomere lengthening in yeast at multiple positions in the telomerase RNP. RNA 17:2, pages 298-311.
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Eleni P Mimitou & Lorraine S Symington. (2010) Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2. The EMBO Journal 29:19, pages 3358-3369.
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Muneyasu Urano, Fuqiu He, Akiko Minami, C. Clifton Ling & Gloria C. Li. (2010) Response to Multiple Radiation Doses of Human Colorectal Carcinoma Cells Infected With Recombinant Adenovirus Containing Dominant-Negative Ku70 Fragment. International Journal of Radiation Oncology*Biology*Physics 77:3, pages 877-885.
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Crossref
Jong-Pil HongMi Young ByunKyungsook AnSae-Jun YangGynheung AnWoo Taek Kim. (2010) OsKu70 Is Associated with Developmental Growth and Genome Stability in Rice      . Plant Physiology 152:1, pages 374-387.
Crossref
Pei Xiong Liew, Feng Ge, Charles Gullo, Gerrard KH Teoh & William YK Hwang. (2009) Use of Phage Display to Isolate Specific Human Monoclonal Antibody Fragments Against a Potential Target for Multiple Myeloma. Annals of the Academy of Medicine, Singapore 38:7, pages 621-629.
Crossref
Giuseppina Turturici, Fabiana Geraci, Maria E. Candela, Giulio Cossu, Giovanni Giudice & Gabriella Sconzo. (2009) Hsp70 is required for optimal cell proliferation in mouse A6 mesoangioblast stem cells. Biochemical Journal 421:2, pages 193-200.
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My-Hang Huynh & Vern B. Carruthers. (2009) Tagging of Endogenous Genes in a Toxoplasma gondii Strain Lacking Ku80 . Eukaryotic Cell 8:4, pages 530-539.
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Daifeng Jiang, YanWen Zhou, Robert A. Moxley & Harry W. Jarrett. (2008) Purification and Identification of Positive Regulators Binding to a Novel Element in the c-Jun Promoter. Biochemistry 47:35, pages 9318-9334.
Crossref
Susanna Cogoi, Manikandan Paramasivam, Barbara Spolaore & Luigi E. Xodo. (2008) Structural polymorphism within a regulatory element of the human KRAS promoter: formation of G4-DNA recognized by nuclear proteins. Nucleic Acids Research 36:11, pages 3765-3780.
Crossref
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Emmanouil Rampakakis, Domenic Di Paola & Maria Zannis-Hadjopoulos. (2008) Ku is involved in cell growth, DNA replication and G1-S transition. Journal of Cell Science 121:5, pages 590-600.
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Manabu Koike & Aki Koike. (2008) Accumulation of Ku80 proteins at DNA double-strand breaks in living cells. Experimental Cell Research 314:5, pages 1061-1070.
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H. Kim. (2006) DNA repair Ku proteins in gastric cancer cells and pancreatic acinar cells. Amino Acids 34:2, pages 195-202.
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Qing-Shan YANG, Jin-Long GU, Li-Qing DU, Li-Li JIA, Li-Li QIN, Yong WANG & Fei-Yue FAN. (2008) ShRNA-mediated Ku80 Gene Silencing Inhibits Cell Proliferation and Sensitizes to γ-radiation and Mitomycin C-induced Apoptosis in Esophageal Squamous Cell Carcinoma Lines. Journal of Radiation Research 49:4, pages 399-407.
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Wen-Chi Chang, Yung-Kai Wang, Pei-Feng Liu, Yu-Fang Tsai, Lih-Ren Kong, Chi-Kai Lin, Chang-Hsien Yang & Rong-Long Pan. (2008) Regulation of Ku gene promoters in Arabidopsis by hormones and stress. Functional Plant Biology 35:4, pages 265.
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Iraimoudi S. Ayene, John E. Biaglow, Alexander V. Kachur, Thomas D. Stamato & Cameron J. Koch. (2008) Mutation in G6PD gene leads to loss of cellular control of protein glutathionylation: Mechanism and implication. Journal of Cellular Biochemistry 103:1, pages 123-135.
Crossref
Maria Zannis‐Hadjopoulos. 2005. Encyclopedia of Life Sciences. Encyclopedia of Life Sciences.
Josefa Cabrero, Rogelio J. Palomino-Morales & Juan Pedro M. Camacho. (2007) The DNA-repair Ku70 protein is located in the nucleus and tail of elongating spermatids in grasshoppers. Chromosome Research 15:8, pages 1093-1100.
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Pei-Feng Liu, Wen-Chi Chang, Yung-Kai Wang, Suresh-Babu Munisamy, Shen-Hsing Hsu, Hwan-You Chang, Shu-Hsing Wu & Rong-Long Pan. (2007) Differential regulation of Ku gene expression in etiolated mung bean hypocotyls by auxins. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1769:7-8, pages 443-454.
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Fuqiu He, Ligeng Li, Dooha Kim, Bixiu Wen, Xuelong Deng, Philip H. Gutin, Clifton C. Ling & Gloria C. Li. (2007) Adenovirus-Mediated Expression of a Dominant Negative Ku70 Fragment Radiosensitizes Human Tumor Cells under Aerobic and Hypoxic Conditions. Cancer Research 67:2, pages 634-642.
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Chan MoonHyung Yoon MoonChul Sung Kim. (2007) The Expressions of p53, γ-H2AX and Ku70 /Ku80 That was Caused by Hydronephrosis in the Kidney of Rats. Korean Journal of Urology 48:9, pages 976.
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Melissa L. Fishel, Michael R. Vasko & Mark R. Kelley. (2007) DNA repair in neurons: So if they don’t divide what's to repair?. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 614:1-2, pages 24-36.
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Ramune Reliene, Marry E.P. Goad & Robert H. Schiestl. (2006) Developmental cell death in the liver and newborn lethality of Ku86 deficient mice suppressed by antioxidant N-acetyl-cysteine. DNA Repair 5:11, pages 1392-1397.
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Charles Gullo, Melvin Au, Ge Feng & Gerrard Teoh. (2006) The biology of Ku and its potential oncogenic role in cancer. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1765:2, pages 223-234.
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Moran Finkel & Haim Cohen. (2005) Models of acetylation and the regulation of longevity: From yeast to humans. Drug Discovery Today: Disease Models 2:4, pages 265-271.
Crossref
Jing An, Qing-Zhi Xu, Jian-Li Sui, Bei Bai & Ping-Kun Zhou. (2005) Downregulation of c-myc protein by siRNA-mediated silencing of DNA-PKcs in HeLa cells. International Journal of Cancer 117:4, pages 531-537.
Crossref
Jill Kuglin Schweitzer & Crislyn D'Souza-Schorey. (2005) A requirement for ARF6 during the completion of cytokinesis. Experimental Cell Research 311:1, pages 74-83.
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Timothy S. Fisher & Virginia A. Zakian. (2005) Ku: A multifunctional protein involved in telomere maintenance. DNA Repair 4:11, pages 1215-1226.
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Shyh-Jen Shih, Tara Erbele & Allan Y. Chen. (2005) Ku86 Modulates DNA Topoisomerase I–Mediated Radiosensitization, but not Cytotoxicity, in Mammalian Cells. Cancer Research 65:20, pages 9194-9199.
Crossref
Maria Zannis‐Hadjopoulos & Gerald B Price. 2005. Encyclopedia of Life Sciences. Encyclopedia of Life Sciences.
Sahar Sibani, Gerald B. Price & Maria Zannis-Hadjopoulos. (2005) Decreased origin usage and initiation of DNA replication in haploinsufficient HCT116 Ku80+/- cells. Journal of Cell Science 118:15, pages 3247-3261.
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Crossref
Sahar Sibani, Gerald B. Price & Maria Zannis-Hadjopoulos. (2005) Ku80 Binds to Human Replication Origins Prior to the Assembly of the ORC Complex. Biochemistry 44:21, pages 7885-7896.
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Manabu Koike & Aki Koike. (2005) The Ku70-binding site of Ku80 is required for the stabilization of Ku70 in the cytoplasm, for the nuclear translocation of Ku80, and for Ku80-dependent DNA repair. Experimental Cell Research 305:2, pages 266-276.
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Riccardo Sgarra, Michela A. Tessari, Julie Di Bernardo, Alessandra Rustighi, Paola Zago, Sabrina Liberatori, Alessandro Armini, Luca Bini, Vincenzo Giancotti & Guidalberto Manfioletti. (2005) Discovering high mobility group A molecular partners in tumour cells. PROTEOMICS 5:6, pages 1494-1506.
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Hannah Elisabeth Mischo, Peter Hemmerich, Frank Grosse & Suisheng Zhang. (2005) Actinomycin D Induces Histone γ-H2AX Foci and Complex Formation of γ-H2AX with Ku70 and Nuclear DNA Helicase II. Journal of Biological Chemistry 280:10, pages 9586-9594.
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Qiaoqiao Wang, Zuo Zhang, Katherine Blackwell & Gordon G. Carmichael. (2005) Vigilins Bind to Promiscuously A-to-I-Edited RNAs and Are Involved in the Formation of Heterochromatin. Current Biology 15:4, pages 384-391.
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Thomas T. MacDonald & Robert D. Miller. 2005. Mucosal Immunology. Mucosal Immunology 323 334 .
Shani Waninger, Kelli Kuhen, Xiuyuan Hu, Jon E. Chatterton, Flossie Wong-Staal & Hengli Tang. (2004) Identification of Cellular Cofactors for Human Immunodeficiency Virus Replication via a Ribozyme-Based Genomics Approach. Journal of Virology 78:23, pages 12829-12837.
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Uğur Saygili, Ilknur Bilkay Gorkay, Meral Koyuncuoglu, Mert Gol, Turhan Uslu & Oktay Erten. (2004) The relationship between expression of Ku70 and survival in irradiated patients with endometrial carcinoma. Gynecologic Oncology 95:3, pages 518-522.
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Habib Boukerche, Zao-Zhong Su, Dong-Chul Kang & Paul B. Fisher. (2004) Identification and cloning of genes displaying elevated expression as a consequence of metastatic progression in human melanoma cells by rapid subtraction hybridization. Gene 343:1, pages 191-201.
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Zuzana Dudášová, Andrej Dudáš & Miroslav Chovanec. (2004) Non-homologous end-joining factors of Saccharomyces cerevisiae . FEMS Microbiology Reviews 28:5, pages 581-601.
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Hongwen MaJoseph ThibaultYali LuCarson WhitingShinong LongGlen LindwallKrista BennettLynn TruongRonald T. AimesFlossie Wong-Staal. (2004) The Development and Applications of Nonradioactive Plate-Formatted DNA-Binding Assay for Ku70/80, a Multifunctional DNA-Binding Protein Complex. ASSAY and Drug Development Technologies 2:5, pages 483-495.
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Elsa Callén & Jordi Surrallés. (2004) Telomere dysfunction in genome instability syndromes. Mutation Research/Reviews in Mutation Research 567:1, pages 85-104.
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Lauren B. Murata, Mark S. Dodson & Jennifer D. Hall. (2004) A Human Cellular Protein Activity (OF-1), Which Binds Herpes Simplex Virus Type 1 Origin, Contains the Ku70/Ku80 Heterodimer. Journal of Virology 78:14, pages 7839-7842.
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Bruno CalabrettaDanilo Perrotti. (2004) The biology of CML blast crisis. Blood 103:11, pages 4010-4022.
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Hong Wang, Ruihua Fang, Je-Yoel Cho, Towia A. Libermann & Peter Oettgen. (2004) Positive and Negative Modulation of the Transcriptional Activity of the ETS Factor ESE-1 through Interaction with p300, CREB-binding Protein, and Ku 70/86. Journal of Biological Chemistry 279:24, pages 25241-25250.
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Clifford L. Wang & Matthias Wabl. (2004) DNA Acrobats of the Ig Class Switch. The Journal of Immunology 172:10, pages 5815-5821.
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David A Somers & Irina Makarevitch. (2004) Transgene integration in plants: poking or patching holes in promiscuous genomes?. Current Opinion in Biotechnology 15:2, pages 126-131.
Crossref
Haim Y Cohen, Siva Lavu, Kevin J Bitterman, Brian Hekking, Thomas A Imahiyerobo, Christine Miller, Roy Frye, Hidde Ploegh, Benedikt M Kessler & David A Sinclair. (2004) Acetylation of the C Terminus of Ku70 by CBP and PCAF Controls Bax-Mediated Apoptosis. Molecular Cell 13:5, pages 627-638.
Crossref
Velen L. Nelson-DeGrave, Jessica K. Wickenheisser, Jennifer E. Cockrell, Jennifer R. Wood, Richard S. Legro, Jerome F. Strauss & Jan M. McAllister. (2004) Valproate Potentiates Androgen Biosynthesis in Human Ovarian Theca Cells. Endocrinology 145:2, pages 799-808.
Crossref
JOANN SEKIGUCHI, FREDERICK W. ALT & MARJORIE OETTINGER. 2004. Molecular Biology of B Cells. Molecular Biology of B Cells 61 82 .
Anne E. Stellwagen, Zara W. Haimberger, Joshua R. Veatch & Daniel E. Gottschling. (2003) Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends. Genes & Development 17:19, pages 2384-2395.
Crossref
Kevin D. Mills, David O. Ferguson & Frederick W. Alt. (2003) The role of DNA breaks in genomic instability and tumorigenesis. Immunological Reviews 194:1, pages 77-95.
Crossref
Andrew D. Smith, Roy F. Collaco & James P. Trempe. (2003) Enhancement of Recombinant Adeno-Associated Virus Type 2-Mediated Transgene Expression in a Lung Epithelial Cell Line by Inhibition of the Epidermal Growth Factor Receptor. Journal of Virology 77:11, pages 6394-6404.
Crossref
András Schaffer, Edmund C. Kim, Xiaoping Wu, Hong Zan, Lucia Testoni, Szilvia Salamon, Andrea Cerutti & Paolo Casali. (2003) Selective Inhibition of Class Switching to IgG and IgE by Recruitment of the HoxC4 and Oct-1 Homeodomain Proteins and Ku70/Ku86 to Newly Identified ATTT cis-Elements. Journal of Biological Chemistry 278:25, pages 23141-23150.
Crossref
John Thacker & Małgorzata Z. Zdzienicka. (2003) The mammalian XRCC genes: their roles in DNA repair and genetic stability. DNA Repair 2:6, pages 655-672.
Crossref
Caroline Schild-PoulterDiamanto Matheos, Olivia Novac, Bo Cui, Ward Giffin, Marcia T. Ruiz, Gerald B. Price, Maria Zannis-Hadjopoulos & Robert J.G. Haché. (2003) Differential DNA Binding of Ku Antigen Determines Its Involvement in DNA Replication. DNA and Cell Biology 22:2, pages 65-78.
Crossref
Diamanto Matheos, Olivia Novac, Gerald B. Price & Maria Zannis-Hadjopoulos. (2003) Analysis of the DNA replication competence of the xrs -5 mutant cells defective in Ku86 . Journal of Cell Science 116:1, pages 111-124.
Crossref
Jesse Bertinato, Julianna J Tomlinson, Caroline Schild-Poulter & Robert J.G Haché. (2003) Evidence implicating Ku antigen as a structural factor in RNA polymerase II-mediated transcription. Gene 302:1-2, pages 53-64.
Crossref
Weihang Chai, Lance P. Ford, Lisa Lenertz, Woodring E. Wright & Jerry W. Shay. (2002) Human Ku70/80 Associates Physically with Telomerase through Interaction with hTERT. Journal of Biological Chemistry 277:49, pages 47242-47247.
Crossref
Joo Weon Lim, Hyeyoung Kim & Kyung Hwan Kim. (2002) Expression of Ku70 and Ku80 Mediated by NF-κB and Cyclooxygenase-2 Is Related to Proliferation of Human Gastric Cancer Cells. Journal of Biological Chemistry 277:48, pages 46093-46100.
Crossref
Sergei K. Svitashev, Wojciech P. Pawlowski, Irina Makarevitch, David W. Plank & David A. Somers. (2002) Complex transgene locus structures implicate multiple mechanisms for plant transgene rearrangement. The Plant Journal 32:4, pages 433-445.
Crossref
David M. Willis, Arleen P. Loewy, Nichole Charlton-Kachigian, Jian-Su Shao, David M. Ornitz & Dwight A. Towler. (2002) Regulation of Osteocalcin Gene Expression by a Novel Ku Antigen Transcription Factor Complex. Journal of Biological Chemistry 277:40, pages 37280-37291.
Crossref
Diamanto Matheos, Marcia T Ruiz, Gerald B Price & Maria Zannis-Hadjopoulos. (2002) Ku antigen, an origin-specific binding protein that associates with replication proteins, is required for mammalian DNA replication. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1578:1-3, pages 59-72.
Crossref
Eun Kyung Choi, Yeon Hee Lee, Yong Seok Choi, Hyock Man Kwon, Mi Sun Choi, Jae Y. Ro, Su-Kil Park & Eunsil Yu. (2002) Heterogeneous expression of Ku70 in human tissues is associated with morphological and functional alterations of the nucleus. The Journal of Pathology 198:1, pages 121-130.
Crossref
Marcia T. Ruiz, Amanda Nichols, Gerald B. Price & Maria Zannis-Hadjopoulos. (2002) DNA-PKcs-OBA/Ku associate in the absence of DNA, as revealed by two-dimensional capillary gel electromobility shift assay. ELECTROPHORESIS 23:15, pages 2485-2489.
Crossref
Michelle L DuBois, Zara W Haimberger, Martin W McIntosh & Daniel E Gottschling. (2002) A Quantitative Assay for Telomere Protection in Saccharomyces cerevisiae . Genetics 161:3, pages 995-1013.
Crossref
Shigenari Omori, Yuichi Takiguchi, Akira Suda, Takaaki Sugimoto, Hiroshi Miyazawa, Yasuo Takiguchi, Nobuhiro Tanabe, Koichiro Tatsumi, Hiroshi Kimura, Paige E. Pardington, Fanqing Chen, David J. Chen & Takayuki Kuriyama. (2002) Suppression of a DNA double-strand break repair gene, Ku70, increases radio- and chemosensitivity in a human lung carcinoma cell line. DNA Repair 1:4, pages 299-310.
Crossref
Katsunori Tamura, Yugo Adachi, Keiko Chiba, Keiko Oguchi & Hideo Takahashi. (2002) Identification of Ku70 and Ku80 homologues in Arabidopsis thaliana : evidence for a role in the repair of DNA double‐strand breaks . The Plant Journal 29:6, pages 771-781.
Crossref
Gang Li, Caron Nelsen & Eric A. Hendrickson. (2002) Ku86 is essential in human somatic cells. Proceedings of the National Academy of Sciences 99:2, pages 832-837.
Crossref
David Alvarez, Olivia Novac, Mario Callejo, Marcia T. Ruiz, Gerald B. Price & Maria Zannis-Hadjopoulos. (2002) 14-3-3? is a cruciform DNA binding protein and associates in vivo with origins of DNA replication. Journal of Cellular Biochemistry 87:2, pages 194-207.
Crossref
Olivia Novac, Diamanto Matheos, Felipe D. Araujo, Gerald B. Price & Maria Zannis-Hadjopoulos. (2001) In Vivo Association of Ku with Mammalian Origins of DNA Replication. Molecular Biology of the Cell 12:11, pages 3386-3401.
Crossref
Å. Larsson, G. Henriksson, R. Manthorpe, A. Sallmyr & A. Bredberg. (2001) Ku Protein and DNA Strand Breaks in Lip Glands of Normal and Primary Sjögren's Syndrome Subjects: Lack of Correlation with Apoptosis. Scandinavian Journal of Immunology 54:3, pages 328-334.
Crossref
V.De Fonzo, E. Bersani, F. Aluffi-Pentini & V. Parisi. (2001) DNA quadruplexes and dynamical genetics. Medical Hypotheses 57:1, pages 103-111.
Crossref
Olga G. ZatsepinaVera V. VelikodvorskaiaVasilii B. MolodtsovDavid GarbuzDaniel N. Lerman, Brian R. Bettencourt, Martin E. Feder & Michael B. Evgenev. (2001) A DROSOPHILA MELANOGASTER Strain From Sub-Equatorial Africa Has Exceptional Thermotolerance But Decreased Hsp70 Expression . Journal of Experimental Biology 204:11, pages 1869-1881.
Crossref
Marika Häkli, Ulla Karvonen, Olli A. Jänne & Jorma J. Palvimo. (2001) The RING Finger Protein SNURF Is a Bifunctional Protein Possessing DNA Binding Activity. Journal of Biological Chemistry 276:26, pages 23653-23660.
Crossref
Caroline Schild-Poulter, Louise Pope, Ward Giffin, Jeff C. Kochan, Johnny K. Ngsee, Maya Traykova-Andonova & Robert J.G. Haché. (2001) The Binding of Ku Antigen to Homeodomain Proteins Promotes Their Phosphorylation by DNA-dependent Protein Kinase. Journal of Biological Chemistry 276:20, pages 16848-16856.
Crossref
Soo‐Hwang Teo & Stephen P Jackson. (2001) Telomerase subunit overexpression suppresses telomere‐specific checkpoint activation in the yeast yku80 mutant . EMBO reports 2:3, pages 197-202.
Crossref
JOHN Y.H. CHAN, LUNG-KUN CHEN, JUI-FENG CHANG, HUI-MIN TING, CHRISTINE GOY, JUI-LIN CHEN, JENG-JONG HWANG, FU-DU CHEN, DAVID J. CHEN & FRANK Q.H. NGO. (2001) Differential Gene Expression in a DNA Double-strand-break Repair Mutant XRS-5 Defective in Ku80: Analysis by cDNA Microarray. Journal of Radiation Research 42:4, pages 371-371.
Crossref
Suzanne E. Peterson, Anne E. Stellwagen, Scott J. Diede, Miriam S. Singer, Zara W. Haimberger, Catherine O. Johnson, Monika Tzoneva & Daniel E. Gottschling. (2001) The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku. Nature Genetics 27:1, pages 64-67.
Crossref
Mark P. Mattson, Weiming Fu & Peisu Zhang. 2001. Telomerase, Aging and Disease. Telomerase, Aging and Disease 131 150 .
Xuan Hoi Pham, Malireddy Kodandarami Reddy, Nasreen Z. Ehtesham, Bharati Matta & Narendra Tuteja. (2001) A DNA helicase from Pisum sativum is homologous to translation initiation factor and stimulates topoisomerase I activity . The Plant Journal 24:2, pages 219-229.
Crossref
Moez Hanin, Tesfaye Mengiste, Augustyn Bogucki & Jerzy Paszkowski. (2001) Elevated levels of intrachromosomal homologous recombination in Arabidopsis overexpressing the MIM gene . The Plant Journal 24:2, pages 183-189.
Crossref
M.L. DUBOIS, S.J. DIEDE, A.E. STELLWAGEN & D.E. GOTTSCHLING. (2000) All Things Must End: Telomere Dynamics in Yeast. Cold Spring Harbor Symposia on Quantitative Biology 65:0, pages 281-296.
Crossref
Richard H. Shafer & Ivan Smirnov. (2000) Biological aspects of DNA/RNA quadruplexes. Biopolymers 56:3, pages 209-227.
Crossref

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