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Review Article

Building up and breaking down: mechanisms controlling recombination during replication

ORCID Icon & ORCID Icon
Pages 381-394 | Received 07 Feb 2017, Accepted 06 Mar 2017, Published online: 22 Mar 2017

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Crossref
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Crossref
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Crossref
Karl-Uwe Reusswig & Boris Pfander. (2019) Control of Eukaryotic DNA Replication Initiation—Mechanisms to Ensure Smooth Transitions. Genes 10:2, pages 99.
Crossref
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Crossref
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Crossref
Takuya Abe, Ryotaro Kawasumi, Michele Giannattasio, Sabrina Dusi, Yui Yoshimoto, Keiji Miyata, Koyuki Umemura, Kouji Hirota & Dana Branzei. (2018) AND-1 fork protection function prevents fork resection and is essential for proliferation. Nature Communications 9:1.
Crossref
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Crossref
Lepakshi Ranjha, Sean M. Howard & Petr Cejka. (2018) Main steps in DNA double-strand break repair: an introduction to homologous recombination and related processes. Chromosoma 127:2, pages 187-214.
Crossref
Dana Branzei & Michele Giannattasio. (2018) SIRFing the replication fork: Assessing protein interactions with nascent DNA. Journal of Cell Biology 217:4, pages 1177-1179.
Crossref
Kyle Kaniecki, Luisina De Tullio & Eric C. Greene. (2017) A change of view: homologous recombination at single-molecule resolution. Nature Reviews Genetics 19:4, pages 191-207.
Crossref
Tricia A Windgassen, Sarah R Wessel, Basudeb Bhattacharyya & James L Keck. (2018) Mechanisms of bacterial DNA replication restart. Nucleic Acids Research 46:2, pages 504-519.
Crossref
Luisina De Tullio, Kyle Kaniecki & Eric C. Greene. 2018. Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination. Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination 407 437 .
Kyle Kaniecki, Luisina De Tullio, Bryan Gibb, Youngho Kwon, Patrick Sung & Eric C. Greene. (2017) Dissociation of Rad51 Presynaptic Complexes and Heteroduplex DNA Joints by Tandem Assemblies of Srs2. Cell Reports 21:11, pages 3166-3177.
Crossref
Luisina De Tullio, Kyle Kaniecki, Youngho Kwon, J. Brooks Crickard, Patrick Sung & Eric C. Greene. (2017) Yeast Srs2 Helicase Promotes Redistribution of Single-Stranded DNA-Bound RPA and Rad52 in Homologous Recombination Regulation. Cell Reports 21:3, pages 570-577.
Crossref