Advanced search
Publication Cover
Leukemia & Lymphoma Volume 58, 2017 - Issue 4
Submit an article Journal homepage
859
Views
15
CrossRef citations to date
0
Altmetric
Reviews

Pegaspargase hypersensitivity reactions: intravenous infusion versus intramuscular injection – a review

Lynda Kwon BeaupinRoswell Park Cancer Institute, Buffalo, NY, USA; Correspondence[email protected]
,
Bruce BostromChildren’s Minnesota, Minneapolis, MN, USA;
,
Matthew J. BarthRoswell Park Cancer Institute, Buffalo, NY, USA;
,
Irene FranklinSigma-Tau Pharmaceuticals, Gaithersburg, MD, USA;
,
Raven JaegerSigma-Tau Pharmaceuticals, Gaithersburg, MD, USA;
,
Priyanka KamathSigma-Tau Pharmaceuticals, Gaithersburg, MD, USA;
,
Brian SchreiberSigma-Tau Pharmaceuticals, Gaithersburg, MD, USA;
&
Archie BleyerOregon Health and Science University, Portland, OR, USA
 show all
Pages 766-772 | Received 01 Feb 2016, Accepted 24 Jul 2016, Published online: 19 Sep 2016

Citations (15)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Krishna R Juluri, Chloe Siu & Ryan D Cassaday. (2022) Asparaginase in the Treatment of Acute Lymphoblastic Leukemia in Adults: Current Evidence and Place in Therapy. Blood and Lymphatic Cancer: Targets and Therapy 12, pages 55-79.
Read now

Articles from other publishers (14)

Hind Salama, Saleem Eldadah, Mohamed H. Omer, Ayman Alhejazi, Luluh Bin Dayil, Ayman Almozaini, Roaa Reda Khalil, Areej Al Mugairi, Mohammed Snnallah, Moussab Damlaj, Ahmed Alaskar, Ahmad Alsaeed, Mohammed Mosa Bakkar, Bader Alahmari, Mohsen Alzahrani, Ihab Elhemaidi, Majed Alahmadi, Sameer Alamoudi, Walaa Rajkhan, Manar Khalil, Solaf Sami Kanfar, Abdullah S. Al Saleh, Abdulrahman Al Raizah, Ayman Ibrahim & Ahmed Absi. (2023) Comparison of a modified pediatric protocol versus a hyper-CVAD protocol in adolescents and young adults with Philadelphia-negative acute lymphoblastic leukemia: A multicenter retrospective analysis. Leukemia Research 130, pages 107316.
Crossref
Line Stensig Lynggaard, Cecilie U Rank, Bodil Als-Nielsen, Sofie G Hoejfeldt, Mats Heyman, Kjeld Schmiegelow & Birgitte K Albertsen. (2023) PEG-asparaginase treatment regimens for acute lymphoblastic leukaemia in children: a network meta-analysis. Cochrane Database of Systematic Reviews 2023:5.
Crossref
Mohamed Ibrahim, Eslam Ramadan, Nehal E. Elsadek, Sherif E. Emam, Taro Shimizu, Hidenori Ando, Yu Ishima, Omar Helmy Elgarhy, Hatem A. Sarhan, Amal K. Hussein & Tatsuhiro Ishida. (2022) Polyethylene glycol (PEG): The nature, immunogenicity, and role in the hypersensitivity of PEGylated products. Journal of Controlled Release 351, pages 215-230.
Crossref
Kjeld Schmiegelow, Cecilie Utke Rank, Wendy Stock, Emily Dworkin & Inge van der Sluis. (2021) SOHO State of the Art Updates and Next Questions: Management of Asparaginase Toxicity in Adolescents and Young Adults with Acute Lymphoblastic Leukemia. Clinical Lymphoma Myeloma and Leukemia 21:11, pages 725-733.
Crossref
Kathleen Busack. (2021) Pegaspargase: Two Pediatric Case Studies of Delayed Urticaria Preceding Anaphylactic Reactions Postadministration. Clinical Journal of Oncology Nursing 25:5, pages 511-513.
Crossref
Meghan McCormick, Jillian Lapinski, Erika Friehling & Kenneth Smith. (2021) Premedication prior to PEG‐asparaginase is cost‐effective in pediatric patients with acute lymphoblastic leukemia. Pediatric Blood & Cancer 68:8.
Crossref
Line Stensig Lynggaard, Cecilie U Rank, Bodil Als-Nielsen, Sofie G Hoejfeldt, Mats Heyman, Kjeld Schmiegelow & Birgitte K Albertsen. (2021) PEG-asparaginase treatment for acute lymphoblastic leukaemia in children: a network meta-analysis. Cochrane Database of Systematic Reviews 2021:6.
Crossref
Alexander Karachunskiy, Gesche Tallen, Julia Roumiantseva, Svetlana Lagoiko, Almira Chervova, Arend von Stackelberg, Olga Aleinikova, Oleg Bydanov, Lyudmila Bajdun, Tatiana Nasedkina, Natalia Korepanova, Sergei Kuznetsov, Galina Novichkova, Marina Goroshkova, Dmitry Litvinov, Natalia Myakova, Natalia Ponomareva, Evgeniya Inyushkina, Konstantin Kondratchik, Julia Abugova, Larisa Fechina, Oleg Arakaev, Alexander Karelin, Vladimir Lebedev, Natalia Judina, Gusel Scharapova, Irina Spichak, Anastasia Shamardina, Olga Ryskal, Alexander Shapochnik, Alexander Rumjanzew, Joachim Boos & Günter Henze. (2019) Reduced vs. standard dose native E. coli-asparaginase therapy in childhood acute lymphoblastic leukemia: long-term results of the randomized trial Moscow–Berlin 2002. Journal of Cancer Research and Clinical Oncology 145:4, pages 1001-1012.
Crossref
Sofie G. Højfeldt, Benjamin O. Wolthers, Morten Tulstrup, Jonas Abrahamsson, Ramneek Gupta, Arja Harila-Saari, Mats Heyman, Louise T. Henriksen, Òlafur G. Jónsson, Päivi M. Lähteenmäki, Bendik Lund, Kaie Pruunsild, Goda Vaitkeviciene, Kjeld Schmiegelow & Birgitte K. Albertsen. (2019) Genetic predisposition to PEG-asparaginase hypersensitivity in children treated according to NOPHO ALL2008. British Journal of Haematology 184:3, pages 405-417.
Crossref
Michael Losasso, Bruce Bostrom & Yoav Messinger. (2020) Retrospective cohort study monitoring PEG-asparaginase activity in acute lymphoblastic leukemia patients with and without premedication. F1000Research 8, pages 1007.
Crossref
Michael Losasso, Bruce Bostrom & Yoav Messinger. (2019) Retrospective cohort study monitoring PEG-asparaginase activity in acute lymphoblastic leukemia patients with and without premedication. F1000Research 8, pages 1007.
Crossref
Haroon Hasan, Omar Mohammad Shaikh, Shahrad Rod Rassekh, A. Fuchsia Howard & Karen Goddard. (2018) Reply to: Comment on: Comparison of hypersensitivity rates to intravenous and intramuscular PEG-asparaginase in children with acute lymphoblastic leukemia: A meta-analysis and systematic review. Pediatric Blood & Cancer 65:8, pages e27106.
Crossref
Hetal G. Dholaria, Amy Davies, Rishi S. Kotecha, Nicholas G. Gottardo & Thomas Walwyn. (2018) Comment on: Comparison of hypersensitivity rates to intravenous and intramuscular PEG-asparaginase in children with acute lymphoblastic leukemia: A meta-analysis and systematic review. Pediatric Blood & Cancer 65:8, pages e27065.
Crossref
Claudia Lanvers-Kaminsky. (2017) Asparaginase pharmacology: challenges still to be faced. Cancer Chemotherapy and Pharmacology 79:3, pages 439-450.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.