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Leukemia & Lymphoma Volume 59, 2018 - Issue 12
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Original Article: Research

Src family kinase inhibitor bosutinib enhances retinoic acid-induced differentiation of HL-60 leukemia cells

Robert J. MacDonaldDepartment of Biomedical Sciences, Cornell University, Ithaca, NY, USA;
,
Rodica P. BunaciuDepartment of Biomedical Sciences, Cornell University, Ithaca, NY, USA;
,
Victoria IpDepartment of Biomedical Sciences, Cornell University, Ithaca, NY, USA;
,
David DaiRobert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY, USA
,
David TranDepartment of Biomedical Sciences, Cornell University, Ithaca, NY, USA;
,
Jeffrey D. VarnerRobert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY, USA
&
Andrew YenDepartment of Biomedical Sciences, Cornell University, Ithaca, NY, USA; Correspondence[email protected]
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Pages 2941-2951 | Received 22 Dec 2017, Accepted 10 Mar 2018, Published online: 23 Mar 2018

Citations (12)

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Noor Kazim & Andrew Yen. (2021) Evidence of off-target effects of bosutinib that promote retinoic acid-induced differentiation of non-APL AML cells. Cell Cycle 20:24, pages 2638-2651.
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Articles from other publishers (11)

Chen Wang, Ravi Nistala, Min Cao, Yi Pan, Madelaine Behrens, Donald Doll, Richard D. Hammer, Puja Nistala, Hui-Ming Chang, Edward T.H. Yeh & XunLei Kang. (2023) Dipeptidylpeptidase 4 promotes survival and stemness of acute myeloid leukemia stem cells. Cell Reports 42:2, pages 112105.
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Kaiyuan Zhu, Noor Kazim, Jianbo Yue & Andrew Yen. (2022) Vacuolin-1 enhances RA-induced differentiation of human myeloblastic leukemia cells: evidence for involvement of a CD11b/FAK/LYN/SLP-76 axis subject to endosomal regulation that drives late differentiation steps. Cell & Bioscience 12:1.
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Fernanda Marconi Roversi, Maura Lima Pereira Bueno, Juliete Aparecida Francisco da Silva, Guilherme Rossi Assis-Mendonça, Cristiane Okuda Torello, Rodrigo Nato Shiraishi, Fernando Viera Pericole, Karla Priscila Ferro, Adriana Santos Silva Duarte, Eduardo Magalhães Rego & Sara Teresinha Olalla Saad. (2022) Novel inhibitor of hematopoietic cell kinase as a potential therapeutic agent for acute myeloid leukemia. Cancer Immunology, Immunotherapy 71:8, pages 1909-1921.
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Abhiruchi Biyanee, Maria V. Yusenko & Karl-Heinz Klempnauer. (2022) Src-Family Protein Kinase Inhibitors Suppress MYB Activity in a p300-Dependent Manner. Cells 11:7, pages 1162.
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Shinichiro Takahashi. (2022) Kinase Inhibitors and Interferons as Other Myeloid Differentiation Inducers in Leukemia Therapy. Acta Haematologica 145:2, pages 113-121.
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Noor Kazim & Andrew Yen. (2021) Role for Fgr and Numb in retinoic acid-induced differentiation and G0 arrest of non-APL AML cells. Oncotarget 12:12, pages 1147-1164.
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Edwige Voisset, Fabienne Brenet, Sophie Lopez & Paulo de Sepulveda. (2020) SRC-Family Kinases in Acute Myeloid Leukaemia and Mastocytosis. Cancers 12:7, pages 1996.
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Asif Rashid, Xin Duan, Feng Gao, Mengsu Yang & Andrew Yen. (2020) Roscovitine enhances All-trans retinoic acid (ATRA)-induced leukemia cell differentiation: Novel effects on signaling molecules for a putative Cdk2 inhibitor. Cellular Signalling 71, pages 109555.
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Kaiyuan Zhu, Jianbo Yue & Andrew Yen. (2020) Depleting interferon regulatory factor‐1(IRF‐1) with CRISPR/Cas9 attenuates inducible oxidative metabolism without affecting RA‐induced differentiation in HL‐60 human AML cells. FASEB BioAdvances 2:6, pages 354-364.
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Asif Rashid, Xin Duan, Feng Gao, Mengsu Yang & Andrew Yen. (2020) Roscovitine enhances all- trans retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signaling molecules and augments ATRA-induced myeloid cell differentiation . Oncotarget 11:12, pages 1017-1036.
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Cheorl-Ho KimCheorl-Ho Kim. 2020. GM3 Signaling. GM3 Signaling 115 131 .

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