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Leukemia & Lymphoma Volume 62, 2021 - Issue 3
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Original Articles

Impact of combinations of single-nucleotide polymorphisms of anthracycline transporter genes upon the efficacy and toxicity of induction chemotherapy in acute myeloid leukemia

Juan Eduardo Megías-Vericata Grupo de Farmacogenética, Instituto Investigación Sanitaria La Fe and Área del Medicamento, Hospital Universitari i Politècnic, Valencia, Spain;b Servicio de Farmacia, Área del Medicamento. Hospital Universitari i Politècnic, Valencia, SpainCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-0369-5341View further author information
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David Martínez-Cuadrónc Servicio de Hematología y Hemoterapia. Hospital Universitari i Politècnic, Valencia, Spain;d CIBERONC, Instituto Carlos III, Madrid, SpainORCID Iconhttps://orcid.org/0000-0001-7540-4091View further author information
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María José Herreroa Grupo de Farmacogenética, Instituto Investigación Sanitaria La Fe and Área del Medicamento, Hospital Universitari i Politècnic, Valencia, Spain;e Departamento Farmacología, Facultad de Medicina, Universidad de Valencia, Valencia, SpainView further author information
,
Rebeca Rodríguez-Veigac Servicio de Hematología y Hemoterapia. Hospital Universitari i Politècnic, Valencia, Spain;d CIBERONC, Instituto Carlos III, Madrid, SpainView further author information
,
Antonio Solana-Altabellab Servicio de Farmacia, Área del Medicamento. Hospital Universitari i Politècnic, Valencia, SpainORCID Iconhttps://orcid.org/0000-0002-8804-3878View further author information
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Blanca Boludac Servicio de Hematología y Hemoterapia. Hospital Universitari i Politècnic, Valencia, Spain;d CIBERONC, Instituto Carlos III, Madrid, SpainORCID Iconhttps://orcid.org/0000-0002-1785-5561View further author information
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Octavio Ballesta-Lópezb Servicio de Farmacia, Área del Medicamento. Hospital Universitari i Politècnic, Valencia, SpainORCID Iconhttps://orcid.org/0000-0002-5444-5836View further author information
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Isabel Canoc Servicio de Hematología y Hemoterapia. Hospital Universitari i Politècnic, Valencia, Spain;d CIBERONC, Instituto Carlos III, Madrid, SpainView further author information
,
Evelyn Acuña-Cruzc Servicio de Hematología y Hemoterapia. Hospital Universitari i Politècnic, Valencia, Spain;d CIBERONC, Instituto Carlos III, Madrid, SpainView further author information
,
José Cerverac Servicio de Hematología y Hemoterapia. Hospital Universitari i Politècnic, Valencia, Spain;d CIBERONC, Instituto Carlos III, Madrid, SpainView further author information
,
José Luis Povedab Servicio de Farmacia, Área del Medicamento. Hospital Universitari i Politècnic, Valencia, SpainView further author information
,
MiguelÁngel Sanzc Servicio de Hematología y Hemoterapia. Hospital Universitari i Politècnic, Valencia, Spain;d CIBERONC, Instituto Carlos III, Madrid, SpainORCID Iconhttps://orcid.org/0000-0003-1489-1177View further author information
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Salvador F. Aliñoa Grupo de Farmacogenética, Instituto Investigación Sanitaria La Fe and Área del Medicamento, Hospital Universitari i Politècnic, Valencia, Spain;e Departamento Farmacología, Facultad de Medicina, Universidad de Valencia, Valencia, Spain;f Unidad de Farmacología Clínica, Área del Medicamento. Hospital Universitari I Politècnic, Valencia, SpainView further author information
&
Pau Montesinosc Servicio de Hematología y Hemoterapia. Hospital Universitari i Politècnic, Valencia, Spain;d CIBERONC, Instituto Carlos III, Madrid, SpainORCID Iconhttps://orcid.org/0000-0002-3275-5593View further author information
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Pages 659-668 | Received 03 Jun 2020, Accepted 13 Oct 2020, Published online: 02 Nov 2020

Citations (9)

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Nadeen Anabtawi, Thomas Drabison, Shuiying Hu, Alex Sparreboom & Zahra Talebi. (2022) The role of OATP1B1 and OATP1B3 transporter polymorphisms in drug disposition and response to anticancer drugs: a review of the recent literature. Expert Opinion on Drug Metabolism & Toxicology 18:7-8, pages 459-468.
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Articles from other publishers (8)

Ming‐Ming Ni, Ju‐Fei Yang, Jing Miao & Jin Xu. (2023) Association between genetic variants of transmembrane transporters and susceptibility to anthracycline‐induced cardiotoxicity: Current understanding and existing evidence. Clinical Genetics.
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Yuyan Wu, Mingying Li, Guangqiang Meng, Yuechan Ma, Jingjing Ye, Tao Sun & Chunyan Ji. (2023) Immune checkpoint‐related gene polymorphisms are associated with acute myeloid leukemia . Cancer Medicine.
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Blanca Boluda, Antonio Solana-Altabella, Isabel Cano, David Martínez-Cuadrón, Evelyn Acuña-Cruz, Laura Torres-Miñana, Rebeca Rodríguez-Veiga, Irene Navarro-Vicente, David Martínez-Campuzano, Raquel García-Ruiz, Pilar Lloret, Pedro Asensi, Ana Osa-Sáez, Jaume Aguero, María Rodríguez-Serrano, Francisco Buendía-Fuentes, Juan Eduardo Megías-Vericat, Beatriz Martín-Herreros, Eva Barragán, Claudia Sargas, Maribel Salas, Margaret Wooddell, Charles Dharmani, Miguel A. Sanz, Javier De la Rubia & Pau Montesinos. (2023) Incidence and Risk Factors for Development of Cardiac Toxicity in Adult Patients with Newly Diagnosed Acute Myeloid Leukemia. Cancers 15:8, pages 2267.
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Ofra Barnett‐Griness, Gad Rennert, Flavio Lejbkowicz, Mila Pinchev, Walid Saliba & Naomi Gronich. (2023) Association Between ABCG2 , ABCB1 , ABCC2 Efflux Transporter Single‐Nucleotide Variants and Irinotecan Adverse Effects in Patients With Colorectal Cancer: A Real‐Life Study . Clinical Pharmacology & Therapeutics 113:3, pages 704-711.
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Luz K. Yunis, Adriana Linares‐Ballesteros, Nelson Aponte, Gisela Barros, Johnny García, Laura Niño, Gloria Uribe, Edna Quintero & Juan J. Yunis. (2022) Pharmacogenetics of ABCB1 , CDA , DCK , GSTT1 , GSTM1 and outcomes in a cohort of pediatric acute myeloid leukemia patients from Colombia . Cancer Reports 6:3.
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Habiba Abdelhalim, Asude Berber, Mudassir Lodi, Rihi Jain, Achuth Nair, Anirudh Pappu, Kush Patel, Vignesh Venkat, Cynthia Venkatesan, Raghu Wable, Matthew Dinatale, Allyson Fu, Vikram Iyer, Ishan Kalove, Marc Kleyman, Joseph Koutsoutis, David Menna, Mayank Paliwal, Nishi Patel, Thirth Patel, Zara Rafique, Rothela Samadi, Roshan Varadhan, Shreyas Bolla, Sreya Vadapalli & Zeeshan Ahmed. (2022) Artificial Intelligence, Healthcare, Clinical Genomics, and Pharmacogenomics Approaches in Precision Medicine. Frontiers in Genetics 13.
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Juan Eduardo Megías-Vericat, David Martínez-Cuadrón, Antonio Solana-Altabella, José Luis Poveda & Pau Montesinos. (2022) Systematic Review of Pharmacogenetics of ABC and SLC Transporter Genes in Acute Myeloid Leukemia. Pharmaceutics 14:4, pages 878.
Crossref
Álvaro Pinto-Merino, Jorge Labrador, Pablo Zubiaur, Raquel Alcaraz, María José Herrero, Pau Montesinos, Francisco Abad-Santos & Miriam Saiz-Rodríguez. (2022) Role of Pharmacogenetics in the Treatment of Acute Myeloid Leukemia: Systematic Review and Future Perspectives. Pharmaceutics 14:3, pages 559.
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