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Research Article

Transport of Chitosan Microparticles for Mucosal Vaccine Delivery in a Human Intestinal M-cell Model

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Pages 449-456 | Published online: 30 Sep 2008

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Read on this site (10)

Kwame G. Yeboah, Janet Akande, Richard T. Addo, Rodney C. Siwale, Kwesi Aninkorah-Yeboah & Aladin Siddig. (2014) In vitro and ex vivo characterization of lectin-labeled Mycobacterium tuberculosis antigen-containing microspheres for enhanced oral delivery. Journal of Drug Targeting 22:1, pages 34-47.
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Mohammad Ariful Islam, Jannatul Firdous, Yun-Jaie Choi, Cheol-Heui Yun & Chong-Su Cho. (2012) Design and application of chitosan microspheres as oral and nasal vaccine carriers: an updated review. International Journal of Nanomedicine 7, pages 6077-6093.
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Valentina Iannuccelli, Monica Montanari, Davide Bertelli, Federica Pellati & Gilberto Coppi. (2011) Microparticulate polyelectrolyte complexes for gentamicin transport across intestinal epithelia. Drug Delivery 18:1, pages 26-37.
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Barbara C. Baudner & Derek T. O’Hagan. (2010) Bioadhesive delivery systems for mucosal vaccine delivery. Journal of Drug Targeting 18:10, pages 752-770.
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Janet Akande, Kwame G. Yeboah, Richard T. Addo, Aladin Siddig, Carl W. Oettinger & Martin J. D'Souza. (2010) Targeted delivery of antigens to the gut-associated lymphoid tissues: 2. Ex vivo evaluation of lectin-labelled albumin microspheres for targeted delivery of antigens to the M-cells of the Peyer's patches. Journal of Microencapsulation 27:4, pages 325-336.
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Yin Hwa Lai & Martin J. D'Souza. (2008) Microparticle transport in the human intestinal M cell model. Journal of Drug Targeting 16:1, pages 36-42.
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Jaleh Varshosaz. (2007) The promise of chitosan microspheres in drug delivery systems. Expert Opinion on Drug Delivery 4:3, pages 263-273.
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Gilberto Coppi, Nicoletta Sala, Moreno Bondi, Santo Sergi & Valentina Iannuccelli. (2006) Ex-vivo evaluation of alginate microparticles for Polymyxin B oral administration. Journal of Drug Targeting 14:9, pages 599-606.
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Monjed Shakweh, Gilles Ponchel & Elias Fattal. (2004) Particle uptake by Peyer’s patches: a pathway for drug and vaccine delivery. Expert Opinion on Drug Delivery 1:1, pages 141-163.
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H. Oya Alpar. (2003) Strategies for Vaccine Delivery. Journal of Drug Targeting 11:8-10, pages 459-461.
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Ludivine Delon, Rachel J. Gibson, Clive A Prestidge & Benjamin Thierry. (2022) Mechanisms of uptake and transport of particulate formulations in the small intestine. Journal of Controlled Release 343, pages 584-599.
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Ashwin C. Parenky, Archana Akalkotkar, Nihal S. Mulla & Martin J. D'Souza. (2019) Harnessing T-cell activity against prostate cancer: A therapeutic microparticulate oral cancer vaccine. Vaccine 37:41, pages 6085-6092.
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Mohammad Ariful Islam, Jannatul Firdous, Abu Zayed Md Badruddoza, Emma Reesor, Mohammad Azad, Anwarul Hasan, Michael Lim, Wuji Cao, Simon Guillemette & Chong Su Cho. (2019) M cell targeting engineered biomaterials for effective vaccination. Biomaterials 192, pages 75-94.
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Puwich Chaikhumwang, Dachrit Nilubol, Angkana Tantituvanont & Pithi Chanvorachote. (2017) A new cell-to-cell interaction model for epithelial microfold cell formation and the enhancing effect of epidermal growth factor. European Journal of Pharmaceutical Sciences 106, pages 49-61.
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Estefanía Blanco-García, Florentina Guerrero-Callejas, José Blanco-Méndez, Hipólito Gómez-Couso & Asteria Luzardo-Álvarez. (2016) Development of particulate drug formulation against C. parvum: Formulation, characterization and in vivo efficacy. European Journal of Pharmaceutical Sciences 92, pages 74-85.
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Ankitkumar S. Jain, Vivek V. Dhawan, Bruno Sarmento & Mangal S. Nagarsenker. (2016) In Vitro and Ex Vivo Evaluations of Lipid Anti-Cancer Nanoformulations: Insights and Assessment of Bioavailability Enhancement. AAPS PharmSciTech 17:3, pages 553-571.
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Yufei Xia, Qingze Fan, Dongxia Hao, Jie Wu, Guanghui Ma & Zhiguo Su. (2015) Chitosan-based mucosal adjuvants: Sunrise on the ocean. Vaccine 33:44, pages 5997-6010.
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Richard T. Addo, Kwame G. Yeboah, Rodney C. Siwale, Aladin Siddig, Alphia Jones, Ruhi V. Ubale, Janet Akande, Henry Nettey, Neil J. Patel, Evelyn Addo & Martin J. D’Souza. (2015) Formulation and Characterization of Atropine Sulfate in Albumin–Chitosan Microparticles for In Vivo Ocular Drug Delivery. Journal of Pharmaceutical Sciences 104:5, pages 1677-1690.
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Sergio A Bucarey, Myriam Pujol, Joaquín Poblete, Ignacio Nuñez, Cecilia V Tapia, Andrónico Neira-Carrillo, Jonatán Martinez & Oliver Bassa. (2014) Chitosan microparticles loaded with yeast-derived PCV2 virus-like particles elicit antigen-specific cellular immune response in mice after oral administration. Virology Journal 11:1.
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Vanessa Liévin-Le Moal & Alain L. Servin. (2013) Pathogenesis of Human Enterovirulent Bacteria: Lessons from Cultured, Fully Differentiated Human Colon Cancer Cell Lines. Microbiology and Molecular Biology Reviews 77:3, pages 380-439.
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Christophe Casteleyn, Wim Van den Broeck, Andreas Gebert, Bart R. Tambuyzer, Steven Van Cruchten & Chris Van Ginneken. (2013) M cell specific markers in man and domestic animals: Valuable tools in vaccine development. Comparative Immunology, Microbiology and Infectious Diseases 36:4, pages 353-364.
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Filipa Antunes, Fernanda Andrade, Francisca Araújo, Domingos Ferreira & Bruno Sarmento. (2013) Establishment of a triple co-culture in vitro cell models to study intestinal absorption of peptide drugs. European Journal of Pharmaceutics and Biopharmaceutics 83:3, pages 427-435.
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Asteria Luzardo Álvarez, Estefanía Blanco García, Florentina Guerrero Callejas, Hipólito Gómez Couso & José Blanco Méndez. (2012) In vitro evaluation of the suppressive effect of chitosan/poly(vinyl alcohol) microspheres on attachment of C. parvum to enterocytic cells. European Journal of Pharmaceutical Sciences 47:1, pages 215-227.
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Yihua Loo, Christopher L. Grigsby, Yvonne J. Yamanaka, Malathi K. Chellappan, Xuan Jiang, Hai-Quan Mao & Kam W. Leong. (2012) Comparative study of nanoparticle-mediated transfection in different GI epithelium co-culture models. Journal of Controlled Release 160:1, pages 48-56.
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Gerrit Borchard, Farnaz Esmaeili & Simon Heuking. 2012. Chitosan‐Based Systems for Biopharmaceuticals. Chitosan‐Based Systems for Biopharmaceuticals 211 224 .
Jinrong Peng, Tingting Qi, Jinfeng Liao, Min Fan, Feng Luo, He Li & Zhiyong Qian. (2012) Synthesis and characterization of novel dual-responsive nanogels and their application as drug delivery systems. Nanoscale 4:8, pages 2694.
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Katharine E. Carr, Sharon H. Smyth, Melissa T. McCullough, John F. Morris & Siobhan M. Moyes. (2012) Morphological aspects of interactions between microparticles and mammalian cells: intestinal uptake and onward movement. Progress in Histochemistry and Cytochemistry 46:4, pages 185-252.
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Yuliang Xiao, Jiangfeng Zhu & Lianyin Zheng. 2011. Chitosan-Based Hydrogels. Chitosan-Based Hydrogels 315 338 .
Manjusha Rani, Anuja Agarwal & Yuvraj Singh Negi. (2011) Characterization and Biodegradation Studies for Interpenetrating Polymeric Network (IPN) of Chitosan-Amino Acid Beads. Journal of Biomaterials and Nanobiotechnology 02:01, pages 71-84.
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S.S. DHADWAR, J. KIERNAN, J. WEN & G. HORTELANO. (2010) Repeated oral administration of chitosan/DNA nanoparticles delivers functional FVIII with the absence of antibodies in hemophilia A mice. Journal of Thrombosis and Haemostasis 8:12, pages 2743-2750.
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Suresh Vyas, Rishi Paliwal & Shivani Paliwal. 2010. Chitin, Chitosan, Oligosaccharides and Their Derivatives. Chitin, Chitosan, Oligosaccharides and Their Derivatives 339 356 .
Filippos Kesisoglou, Phyllissa Schmiedlin-Ren, David Fleisher & Ellen M. Zimmermann. (2010) Adenoviral Transduction of Enterocytes and M-Cells Using in Vitro Models Based on Caco-2 Cells: The Coxsackievirus and Adenovirus Receptor (CAR) Mediates Both Apical and Basolateral Transduction . Molecular Pharmaceutics 7:3, pages 619-629.
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S.M. Moyes, J.F. Morris & K.E. Carr. (2010) Culture conditions and treatments affect Caco-2 characteristics and particle uptake. International Journal of Pharmaceutics 387:1-2, pages 7-18.
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Irina Kadiyala, Yihua Loo, Krishnendu Roy, Janet Rice & Kam W. Leong. (2010) Transport of chitosan–DNA nanoparticles in human intestinal M-cell model versus normal intestinal enterocytes. European Journal of Pharmaceutical Sciences 39:1-3, pages 103-109.
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H. Onishi. (2010) Chitosan microparticles. Journal of Drug Delivery Science and Technology 20:1, pages 15-22.
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Niels Hagenaars, Enrico Mastrobattista, Rolf J. Verheul, Imke Mooren, Harrie L. Glansbeek, Jacco G. M. Heldens, Han van den Bosch & Wim Jiskoot. (2009) Physicochemical and Immunological Characterization of N,N,N-Trimethyl Chitosan-Coated Whole Inactivated Influenza Virus Vaccine for Intranasal Administration. Pharmaceutical Research 26:6, pages 1353-1364.
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XingYi Li, XiangYe Kong, Shuai Shi, XiuLing Zheng, Gang Guo, YuQuan Wei & ZhiYong Qian. (2008) Preparation of alginate coated chitosan microparticles for vaccine delivery. BMC Biotechnology 8:1.
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Mallika DasHong ZhangEugenia Kumacheva. (2006) MICROGELS: Old Materials with New Applications. Annual Review of Materials Research 36:1, pages 117-142.
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Saraporn Harikarnpakdee, Vimolmas Lipipun, Narueporn Sutanthavibul & Garnpimol C. Ritthidej. (2017) Spray-dried mucoadhesive microspheres: Preparation and transport through nasal cell monolayer. AAPS PharmSciTech 7:1, pages E79-E88.
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Nadja Knop & Erich Knop. (2005) Ultrastructural anatomy of CALT follicles in the rabbit reveals characteristics of M-cells, germinal centres and high endothelial venules. Journal of Anatomy 207:4, pages 409-426.
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Franziska Roth-Walter, Barbara Bohle, Isabella Schöll, Eva Untersmayr, Otto Scheiner, George Boltz-Nitulescu, Franz Gabor, David J. Brayden & Erika Jensen-Jarolim. (2005) Targeting antigens to murine and human M-cells with Aleuria aurantia lectin-functionalized microparticles. Immunology Letters 100:2, pages 182-188.
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David J. Brayden, Mark A. Jepson & Alan W. Baird. (2005) Keynote review: Intestinal Peyer's patch M cells and oral vaccine targeting. Drug Discovery Today 10:17, pages 1145-1157.
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Mika Hori, Hiraku Onishi & Yoshiharu Machida. (2005) Evaluation of Eudragit-coated chitosan microparticles as an oral immune delivery system. International Journal of Pharmaceutics 297:1-2, pages 223-234.
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Isabella Schöll, George Boltz-Nitulescu & Erika Jensen-Jarolim. (2005) Review of novel particulate antigen delivery systems with special focus on treatment of type I allergy. Journal of Controlled Release 104:1, pages 1-27.
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George T. MercierJacquelyn A. CampbellJames D. ChappellThilo StehleTerence S. DermodyMichael A. Barry. (2004) A chimeric adenovirus vector encoding reovirus attachment protein σ1 targets cells expressing junctional adhesion molecule 1. Proceedings of the National Academy of Sciences 101:16, pages 6188-6193.
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Mark A. Jepson, M.Ann Clark & Barry H. Hirst. (2004) M cell targeting by lectins: a strategy for mucosal vaccination and drug delivery. Advanced Drug Delivery Reviews 56:4, pages 511-525.
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