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Research Article

Celecoxib Incorporated Chitosan Microspheres: In Vitro and In Vivo Evaluation

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Pages 549-557 | Received 19 May 2004, Accepted 01 Sep 2004, Published online: 03 Oct 2008

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Dalia M. Ghorab, Maha Mohamed Amin, Omneya M. Khowessah & Mina Ibrahim Tadros. (2011) Colon-targeted celecoxib-loaded Eudragit® S100-coated poly-ϵ-caprolactone microparticles: Preparation, characterization and in vivo evaluation in rats. Drug Delivery 18:7, pages 523-535.
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Miha Homar, Nathalie Ubrich, Fatima El Ghazouani, Julijana Kristl, Janez Kerč & Philippe Maincent. (2007) Influence of polymers on the bioavailability of microencapsulated celecoxib. Journal of Microencapsulation 24:7, pages 621-633.
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Nagwa H. Foda, Hanan M. El-laithy & Mina I. Tadros. (2007) Implantable Biodegradable Sponges: Effect of Interpolymer Complex Formation of Chitosan With Gelatin on the Release Behavior of Tramadol Hydrochloride. Drug Development and Industrial Pharmacy 33:1, pages 7-17.
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Ying Lu, Guoqing Zhang, Duxin Sun & Yanqiang Zhong$suffix/text()$suffix/text(). (2007) Preparation and evaluation of biodegradable flubiprofen gelatin micro-spheres for intra-articular administration. Journal of Microencapsulation 24:6, pages 515-524.
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. (2005) Literature Alerts. Drug Delivery 12:4, pages 237-248.
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Brittany D. Partain, Mythreyi Unni, Carlos Rinaldi & Kyle D. Allen. (2020) The clearance and biodistribution of magnetic composite nanoparticles in healthy and osteoarthritic rat knees. Journal of Controlled Release 321, pages 259-271.
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Timothy K. Mwangi, Ian M. Berke, Eduardo H. Nieves, Richard D. Bell, Samuel B. Adams & Lori A. Setton. (2018) Intra-articular clearance of labeled dextrans from naive and arthritic rat knee joints. Journal of Controlled Release 283, pages 76-83.
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Juanjuan Yi, Cuilin Cheng, Shubin Li, Dong Wang, Lu Wang & Zhenyu Wang. (2018) Preparation optimization and protective effect on 60Co-γ radiation damage of Pinus koraiensis pinecone polyphenols microspheres. International Journal of Biological Macromolecules 113, pages 583-591.
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Jing-Wen Guo, Pei-Pei Guan, Wei-Yan Ding, Si-Ling Wang, Xue-Shi Huang, Zhan-You Wang & Pu Wang. (2017) Erythrocyte membrane-encapsulated celecoxib improves the cognitive decline of Alzheimer's disease by concurrently inducing neurogenesis and reducing apoptosis in APP/PS1 transgenic mice. Biomaterials 145, pages 106-127.
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Mayur M. Patel. (2017) Formulation and development of di-dependent microparticulate system for colon-specific drug delivery. Drug Delivery and Translational Research 7:2, pages 312-324.
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Lívia M. D. Loiola, Pablo R. Cortez Tornello, Gustavo A. Abraham & Maria I. Felisberti. (2017) Amphiphilic electrospun scaffolds of PLLA–PEO–PPO block copolymers: preparation, characterization and drug-release behaviour. RSC Advances 7:1, pages 161-172.
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Maria J. Sandker, Luisa F. Duque, Everaldo M. Redout, Alan Chan, Ivo Que, Clemens W.G.M. Löwik, Evelien C. Klijnstra, Nicole Kops, Rob Steendam, Rene van Weeren, Wim E. Hennink & Harrie Weinans. (2017) Degradation, intra-articular retention and biocompatibility of monospheres composed of [PDLLA-PEG-PDLLA]-b-PLLA multi-block copolymers. Acta Biomaterialia 48, pages 401-414.
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Maarten Janssen, Ufuk Tan Timur, Nina Woike, Tim J.M. Welting, Guy Draaisma, Marion Gijbels, Lodewijk W. van Rhijn, George Mihov, Jens Thies & Pieter J. Emans. (2016) Celecoxib-loaded PEA microspheres as an auto regulatory drug-delivery system after intra-articular injection. Journal of Controlled Release 244, pages 30-40.
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Hend Abd-Allah, Amany O. Kamel & Omaima A. Sammour. (2016) Injectable long acting chitosan/tripolyphosphate microspheres for the intra-articular delivery of lornoxicam: Optimization and in vivo evaluation. Carbohydrate Polymers 149, pages 263-273.
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R. S Acharya & R. V. P Reddy. (2015) GLUTATHIONE CONJUGATED PLGA NANOPARTICLES FOR ENHANCED BRAIN TARGETED DELIVERY OF A FLUORESCENT MARKER. INDIAN DRUGS 52:10, pages 23-33.
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Timothy K. Mwangi, Robby D. Bowles, David M. Tainter, Richard D. Bell, David L. Kaplan & Lori A. Setton. (2015) Synthesis and characterization of silk fibroin microparticles for intra-articular drug delivery. International Journal of Pharmaceutics 485:1-2, pages 7-14.
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Hsiao-yin Yang, Maarten van Dijk, Ruud Licht, Michiel Beekhuizen, Mattie van Rijen, Martina Källrot Janstål, F. Cumhur Öner, Wouter J. A. Dhert, Detlef Schumann & Laura B. Creemers. (2014) Applicability of a Newly Developed Bioassay for Determining Bioactivity of Anti-Inflammatory Compounds in Release Studies − Celecoxib and Triamcinolone Acetonide Released from Novel PLGA-Based Microspheres. Pharmaceutical Research 32:2, pages 680-690.
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Maarten Janssen, George Mihov, Tim Welting, Jens Thies & Pieter Emans. (2014) Drugs and Polymers for Delivery Systems in OA Joints: Clinical Needs and Opportunities. Polymers 6:3, pages 799-819.
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Laurent Bédouet, Laurence Moine, Florentina Pascale, Van-Nga Nguyen, Denis Labarre & Alexandre Laurent. (2014) Synthesis of hydrophilic intra-articular microspheres conjugated to ibuprofen and evaluation of anti-inflammatory activity on articular explants. International Journal of Pharmaceutics 459:1-2, pages 51-61.
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Laurent Bédouet, Florentina Pascale, Laurence Moine, Michel Wassef, Saïda H. Ghegediban, Van-Nga Nguyen, Michel Bonneau, Denis Labarre & Alexandre Laurent. (2013) Intra-articular fate of degradable poly(ethyleneglycol)-hydrogel microspheres as carriers for sustained drug delivery. International Journal of Pharmaceutics 456:2, pages 536-544.
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Carmela Cannavà, Silvana Tommasini, Rosanna Stancanelli, Venera Cardile, Felisa Cilurzo, Ignazio Giannone, Giovanni Puglisi & Cinzia Anna Ventura. (2013) Celecoxib-loaded PLGA/cyclodextrin microspheres: Characterization and evaluation of anti-inflammatory activity on human chondrocyte cultures. Colloids and Surfaces B: Biointerfaces 111, pages 289-296.
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Maria J. Sandker, Audrey Petit, Everaldo M. Redout, Michiel Siebelt, Benno Müller, Peter Bruin, Ronald Meyboom, Tina Vermonden, Wim E. Hennink & Harrie Weinans. (2013) In situ forming acyl-capped PCLA–PEG–PCLA triblock copolymer based hydrogels. Biomaterials 34:32, pages 8002-8011.
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Shachar Patchornik, Edward Ram, Noah Ben Shalom, Zvi Nevo & Dror Robinson. (2012) Chitosan-Hyaluronate Hybrid Gel Intraarticular Injection Delays Osteoarthritis Progression and Reduces Pain in a Rat Meniscectomy Model as Compared to Saline and Hyaluronate Treatment. Advances in Orthopedics 2012, pages 1-5.
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N. Mennini, S. Furlanetto, M. Cirri & P. Mura. (2012) Quality by design approach for developing chitosan-Ca-alginate microspheres for colon delivery of celecoxib-hydroxypropyl-β-cyclodextrin-PVP complex. European Journal of Pharmaceutics and Biopharmaceutics 80:1, pages 67-75.
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J. Pradal, O. Jordan & E. Allémann. (2012) Intra-articular drug delivery for arthritis diseases: the value of extended release and targeting strategies. Journal of Drug Delivery Science and Technology 22:5, pages 409-419.
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Sanjay B. Patil, Ankur Kaul, Anil Babbar, Rashi Mathur, Anil Mishra & Krutika K. Sawant. (2012) In vivo evaluation of alginate microspheres of carvedilol for nasal delivery. Journal of Biomedical Materials Research Part B: Applied Biomaterials 100B:1, pages 249-255.
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Adam Bohr, Jakob Kristensen, Eleanor Stride, Mark Dyas & Mohan Edirisinghe. (2011) Preparation of microspheres containing low solubility drug compound by electrohydrodynamic spraying. International Journal of Pharmaceutics 412:1-2, pages 59-67.
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S. Jose, M.T. Prema, A.J. Chacko, A. Cinu Thomas & E.B. Souto. (2011) Colon specific chitosan microspheres for chronotherapy of chronic stable angina. Colloids and Surfaces B: Biointerfaces 83:2, pages 277-283.
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Venkatachalam Natarajan, Natarajan Krithica, Balaraman Madhan & Praveen Kumar Sehgal. (2011) Formulation and Evaluation of Quercetin Polycaprolactone Microspheres for the Treatment of Rheumatoid Arthritis. Journal of Pharmaceutical Sciences 100:1, pages 195-205.
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Asli Deniz, Asli Sade, Feride Severcan, Dilek Keskin, Aysen Tezcaner & Sreeparna Banerjee. (2010) Celecoxib-loaded liposomes: effect of cholesterol on encapsulation and in vitro release characteristics . Bioscience Reports 30:5, pages 365-373.
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Heidi M. Mansour, MinJi Sohn, Abeer Al-Ghananeem & Patrick P. DeLuca. (2010) Materials for Pharmaceutical Dosage Forms: Molecular Pharmaceutics and Controlled Release Drug Delivery Aspects. International Journal of Molecular Sciences 11:9, pages 3298-3322.
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Claus Larsen, Jesper Østergaard, Susan W. Larsen, Henrik Jensen, Stine Jacobsen, Casper Lindegaard & Pia H. Andersen. (2008) Intra‐articular depot formulation principles: Role in the management of postoperative pain and arthritic disorders. Journal of Pharmaceutical Sciences 97:11, pages 4622-4654.
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Helawe Betre, Wenge Liu, Michael R. Zalutsky, Ashutosh Chilkoti, Virginia B. Kraus & Lori A. Setton. (2006) A thermally responsive biopolymer for intra-articular drug delivery. Journal of Controlled Release 115:2, pages 175-182.
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